CO5080825A1 - Sistema de terapia con genes suicidas para el tratamiento de tumores cerebrales - Google Patents

Sistema de terapia con genes suicidas para el tratamiento de tumores cerebrales

Info

Publication number
CO5080825A1
CO5080825A1 CO99016563A CO99016563A CO5080825A1 CO 5080825 A1 CO5080825 A1 CO 5080825A1 CO 99016563 A CO99016563 A CO 99016563A CO 99016563 A CO99016563 A CO 99016563A CO 5080825 A1 CO5080825 A1 CO 5080825A1
Authority
CO
Colombia
Prior art keywords
treatment
brain tumors
therapy system
suicide genes
container contains
Prior art date
Application number
CO99016563A
Other languages
English (en)
Inventor
Marta Izquierdo
Maria Luisa Cortes
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of CO5080825A1 publication Critical patent/CO5080825A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2445—Beta-glucosidase (3.2.1.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01021—Beta-glucosidase (3.2.1.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Estuche para el tratamiento de tumores cerebrales, en el que un primer recipiente contiene la preparación con la molécula de ácido nucleico que codifica la glicosidasa, y en el que un segundo recipiente contiene el substrato cianogénico.
CO99016563A 1998-03-17 1999-03-17 Sistema de terapia con genes suicidas para el tratamiento de tumores cerebrales CO5080825A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98104756A EP0943680A1 (en) 1998-03-17 1998-03-17 Suicide gene therapy system for the treatment of brain tumours

Publications (1)

Publication Number Publication Date
CO5080825A1 true CO5080825A1 (es) 2001-09-25

Family

ID=8231598

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99016563A CO5080825A1 (es) 1998-03-17 1999-03-17 Sistema de terapia con genes suicidas para el tratamiento de tumores cerebrales

Country Status (8)

Country Link
EP (2) EP0943680A1 (es)
JP (1) JP2002506885A (es)
AR (1) AR014733A1 (es)
AU (1) AU3329999A (es)
CA (1) CA2323897A1 (es)
CO (1) CO5080825A1 (es)
WO (1) WO1999047653A1 (es)
ZA (1) ZA992063B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2304276B1 (es) * 2005-12-23 2009-07-28 Universidad Autonoma De Madrid Uam Efecto sinergico entre un sistema cianogenico y otro inductor oxidativo para el tratamiento de tumores.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9001641D0 (en) * 1990-01-24 1990-03-21 Imp Cancer Res Tech Compounds
US5529774A (en) * 1991-08-13 1996-06-25 The Regents Of The University Of California In vivo transfer of the HSV-TK gene implanted retroviral producer cells
WO1994028127A1 (en) * 1993-05-24 1994-12-08 Imperial Cancer Research Technology Limited Cancer treatment
JPH09248182A (ja) * 1996-03-15 1997-09-22 Oyo Seikagaku Kenkyusho プラスミド包埋多重膜リポソーム
US6027721A (en) * 1996-05-20 2000-02-22 Cytotherapeutics, Inc. Device and method for encapsulated gene therapy

Also Published As

Publication number Publication date
CA2323897A1 (en) 1999-09-23
AR014733A1 (es) 2001-03-28
EP1062328A1 (en) 2000-12-27
AU3329999A (en) 1999-10-11
ZA992063B (en) 1999-09-17
EP0943680A1 (en) 1999-09-22
JP2002506885A (ja) 2002-03-05
WO1999047653A1 (en) 1999-09-23

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