CO4970832A1 - NEW FORMULATIONS AND PROCESSES FOR ITS MANUFACTURE - Google Patents

NEW FORMULATIONS AND PROCESSES FOR ITS MANUFACTURE

Info

Publication number
CO4970832A1
CO4970832A1 CO98068459A CO98068459A CO4970832A1 CO 4970832 A1 CO4970832 A1 CO 4970832A1 CO 98068459 A CO98068459 A CO 98068459A CO 98068459 A CO98068459 A CO 98068459A CO 4970832 A1 CO4970832 A1 CO 4970832A1
Authority
CO
Colombia
Prior art keywords
manufacture
processes
paroxetine
new formulations
solution
Prior art date
Application number
CO98068459A
Other languages
Spanish (es)
Inventor
Ahmad Ghazawi
Stanley Leonard Graham
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of CO4970832A1 publication Critical patent/CO4970832A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Abstract

Una cápsula oral tragable, que contiene paroxetina disuelta en un vehículo. Una cápsula oral tragable, que comprende una cubierta de cápsula que contiene paroxetina como la base libre o una sal o solvato farmacéuticamente aceptable de la misma, en disolución en un vehículo líquido o sólido. 1Una formulación farmacéutica, que comprende una disolución de paroxetina en una mezcla de un agente solubilizante y un lípido y/o aceite.A swallowable oral capsule, containing paroxetine dissolved in a vehicle. A swallowable oral capsule, comprising a capsule shell containing paroxetine as the free base or a pharmaceutically acceptable salt or solvate thereof, in solution in a liquid or solid vehicle. 1A pharmaceutical formulation, comprising a solution of paroxetine in a mixture of a solubilizing agent and a lipid and / or oil.

CO98068459A 1997-11-21 1998-11-20 NEW FORMULATIONS AND PROCESSES FOR ITS MANUFACTURE CO4970832A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9724544.3A GB9724544D0 (en) 1997-11-21 1997-11-21 Novel Formulation

Publications (1)

Publication Number Publication Date
CO4970832A1 true CO4970832A1 (en) 2000-11-07

Family

ID=10822374

Family Applications (1)

Application Number Title Priority Date Filing Date
CO98068459A CO4970832A1 (en) 1997-11-21 1998-11-20 NEW FORMULATIONS AND PROCESSES FOR ITS MANUFACTURE

Country Status (24)

Country Link
EP (1) EP1033986A1 (en)
JP (1) JP2001523718A (en)
KR (1) KR20010032320A (en)
CN (1) CN1279608A (en)
AP (1) AP2000001821A0 (en)
AR (1) AR015485A1 (en)
AU (1) AU1168099A (en)
BG (1) BG104527A (en)
BR (1) BR9814220A (en)
CO (1) CO4970832A1 (en)
DZ (1) DZ2658A1 (en)
EA (1) EA200000552A1 (en)
GB (1) GB9724544D0 (en)
HU (1) HUP0100580A3 (en)
IL (1) IL136106A0 (en)
MA (1) MA24704A1 (en)
NO (1) NO20002590L (en)
OA (1) OA11385A (en)
PE (1) PE20000381A1 (en)
PL (1) PL340555A1 (en)
SK (1) SK7342000A3 (en)
TR (1) TR200001423T2 (en)
WO (1) WO1999026625A1 (en)
ZA (1) ZA9810637B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9810180D0 (en) * 1998-05-13 1998-07-08 Smithkline Beecham Plc Novel formulation
EP1161241B1 (en) 1999-03-12 2005-12-07 Aesica Pharmaceuticals Ltd. Stable pharmaceutical application form for paroxetin anhydrate
DK1109806T3 (en) 1999-07-01 2003-12-22 Italfarmaco Spa Complexes of paroxetine with cyclodextrins or cyclodextrin derivatives
DE19930454A1 (en) * 1999-07-02 2001-01-04 Knoll Ag Solid paroxetine-containing preparations
US6720003B2 (en) 2001-02-16 2004-04-13 Andrx Corporation Serotonin reuptake inhibitor formulations
CA2466868C (en) * 2001-12-21 2010-06-22 Shire Laboratories Inc. Oral capsule formulation with increased physical stability
SE0200475D0 (en) * 2002-02-15 2002-02-15 Ltp Lipid Technologies Provide Oral pharmaceutical preparation
WO2006119779A2 (en) * 2005-05-10 2006-11-16 Lifecycle Pharma A/S A pharmaceutical composition comprising an aldosterone antagonist in form of solid solution
CN102740841A (en) * 2009-12-08 2012-10-17 株式会社一和 Solid dispersions containing 20-O-beta-D-glucopyranosyl-20(S)-protopanaxadiol
GB201020032D0 (en) * 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
CN103961333B (en) * 2014-05-07 2020-02-21 浙江华海药业股份有限公司 Paroxetine mesylate capsule and preparation method thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0818990A1 (en) * 1995-04-03 1998-01-21 Abbott Laboratories Homogeneous mixtures of low temperature-melting drugs and additives for controlled release
EP0952831A1 (en) * 1997-01-15 1999-11-03 Smithkline Beecham Plc Paroxetine compositions

Also Published As

Publication number Publication date
SK7342000A3 (en) 2000-12-11
PL340555A1 (en) 2001-02-12
NO20002590L (en) 2000-07-19
PE20000381A1 (en) 2000-05-07
BG104527A (en) 2001-04-30
JP2001523718A (en) 2001-11-27
CN1279608A (en) 2001-01-10
NO20002590D0 (en) 2000-05-19
TR200001423T2 (en) 2000-10-23
EA200000552A1 (en) 2000-10-30
HUP0100580A3 (en) 2002-05-28
AR015485A1 (en) 2001-05-02
GB9724544D0 (en) 1998-01-21
BR9814220A (en) 2001-12-26
AP2000001821A0 (en) 2000-06-30
HUP0100580A2 (en) 2002-04-29
OA11385A (en) 2004-01-27
WO1999026625A1 (en) 1999-06-03
AU1168099A (en) 1999-06-15
KR20010032320A (en) 2001-04-16
IL136106A0 (en) 2001-05-20
EP1033986A1 (en) 2000-09-13
DZ2658A1 (en) 2003-03-22
ZA9810637B (en) 2000-05-22
MA24704A1 (en) 1999-07-01

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