CO4940425A1 - FORMULA I TETRAHYDROPYRIDINE COMPOUNDS AND THE MEDICINAL PRODUCT CONTAINING THEM - Google Patents
FORMULA I TETRAHYDROPYRIDINE COMPOUNDS AND THE MEDICINAL PRODUCT CONTAINING THEMInfo
- Publication number
- CO4940425A1 CO4940425A1 CO98016265A CO98016265A CO4940425A1 CO 4940425 A1 CO4940425 A1 CO 4940425A1 CO 98016265 A CO98016265 A CO 98016265A CO 98016265 A CO98016265 A CO 98016265A CO 4940425 A1 CO4940425 A1 CO 4940425A1
- Authority
- CO
- Colombia
- Prior art keywords
- hydrogen
- alkoxy
- 4alkoxy
- substituents
- signifies
- Prior art date
Links
Abstract
La presente invención se relaciona con compuestos de lafórmula Ien la cual R1 significa alquilo C1-4 R2 significa alquilo C1-4 o hidroxi-alquilo C1-4, R3 significa hidrógeno o halógeno, uno de los sustituyentes R4a y R4b significa hidrógeno, y el otro significa hidrógeno, hidroxi, alcoxi C1-4, alcoxi C1-4-alcoxi C1-4 o alquil C1-4-carboniloxi o en la cual R4a y R4b juntos representan O (oxígeno), uno de los sustituyentes R5a y R5b significa hidrógeno, y el otro significa hidrógeno, hidroxi, alcoxi C1-4, alcoxi C1-4-alcoxi C1-4 o alquil C1-4-carboniloxi, o en la cual R5a y R5b juntos representan O (oxígeno), o en la cual uno de los sustituyentes R4a y R4b por otra parte y uno de los sustituyentes R5a y R5b por parte significan en cada caso hidrógeno, y los otros sustituyentes en cada caso forman juntos un radical metilenodioxi (-O-CH2-O-) o un radical etilenodioxi (-O-CH2-CH2-O-), donde R4a, R4b, R5a y R5b no tienen simultáneamente el significado de hidrógeno, R6 significa hidrógeno, halógeno, alquilo C1-4, alcoxi C1-4, alcoxi C1-4-carnonilamino, alcoxi C1-4- alcoxi C1-4-carbonilamino o trifluorometilo y R7 significa hidrógeno, halógeno, alquilo C1-4 o alcoxi C1-4, y sus sales. Adicionalmente también se relaciona con un medicamento que contiene un compuesto de acuerdo con la reivindicación 1 y/o una de sus sales farmacológicamente compatibles, junto con materiales adyuvantes y/o vehículos farmacéuticos convencionales.The present invention relates to compounds of the formula I in which R1 signifies C1-4 alkyl R2 signifies C1-4 alkyl or hydroxy-C1-4 alkyl, R3 signifies hydrogen or halogen, one of the substituents R4a and R4b signifies hydrogen, and the other means hydrogen, hydroxy, C1-4 alkoxy, C1-4 alkoxy-C1-4 alkoxy or C1-4alkylcarbonyloxy or in which R4a and R4b together represent O (oxygen), one of the substituents R5a and R5b stands for hydrogen , and the other means hydrogen, hydroxy, C1-4 alkoxy, C1-4 alkoxy-C1-4 alkoxy, or C1-4alkylcarbonyloxy, or in which R5a and R5b together represent O (oxygen), or in which one of the substituents R4a and R4b on the other hand and one of the substituents R5a and R5b on the other hand signify hydrogen, and the other substituents in each case together form a methylenedioxy radical (-O-CH2-O-) or an ethylenedioxy radical (-O-CH2-CH2-O-), where R4a, R4b, R5a and R5b do not simultaneously have the meaning of hydrogen, R6 means hydrogen, halogen, C1-4alkyl, C1-4alkoxy, C1-4alkoxy-carnynylamino, C1-4alkoxy-C1-4alkoxy-carbonylamino or trifluoromethyl and R7 means hydrogen, halogen, C1-4alkyl or C1-4alkoxy , and its salts. Additionally, it is also related to a medicine that contains a compound according to claim 1 and / or one of its pharmacologically compatible salts, together with adjuvant materials and / or conventional pharmaceutical vehicles.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19712322 | 1997-03-24 | ||
| DE19747929 | 1997-10-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO4940425A1 true CO4940425A1 (en) | 2000-07-24 |
Family
ID=26035179
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO98016265A CO4940425A1 (en) | 1997-03-24 | 1998-03-24 | FORMULA I TETRAHYDROPYRIDINE COMPOUNDS AND THE MEDICINAL PRODUCT CONTAINING THEM |
Country Status (8)
| Country | Link |
|---|---|
| AR (1) | AR011460A1 (en) |
| CO (1) | CO4940425A1 (en) |
| GE (1) | GEP20012445B (en) |
| HR (1) | HRP980147B1 (en) |
| MY (1) | MY116727A (en) |
| PE (1) | PE61999A1 (en) |
| SA (1) | SA98190059B1 (en) |
| TW (1) | TW593320B (en) |
-
1998
- 1998-03-16 MY MYPI9801137 patent/MY116727A/en unknown
- 1998-03-19 TW TW87104064A patent/TW593320B/en not_active IP Right Cessation
- 1998-03-19 GE GEAP19984985A patent/GEP20012445B/en unknown
- 1998-03-20 PE PE00020198A patent/PE61999A1/en not_active Application Discontinuation
- 1998-03-20 HR HRP980147 patent/HRP980147B1/en not_active IP Right Cessation
- 1998-03-24 CO CO98016265A patent/CO4940425A1/en unknown
- 1998-03-24 AR ARP980101329 patent/AR011460A1/en active IP Right Grant
- 1998-05-12 SA SA98190059A patent/SA98190059B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SA98190059B1 (en) | 2006-08-12 |
| HRP980147B1 (en) | 2002-08-31 |
| PE61999A1 (en) | 1999-06-19 |
| MY116727A (en) | 2004-03-31 |
| AR011460A1 (en) | 2000-08-16 |
| GEP20012445B (en) | 2001-05-25 |
| HRP980147A2 (en) | 1999-02-28 |
| TW593320B (en) | 2004-06-21 |
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