CO4700418A1 - INHIBITION OF THE PHOTODESCOMPOSITION OF 2-OXYDOLES 3-SUSTI- TIDES - Google Patents

INHIBITION OF THE PHOTODESCOMPOSITION OF 2-OXYDOLES 3-SUSTI- TIDES

Info

Publication number
CO4700418A1
CO4700418A1 CO96019210A CO96019210A CO4700418A1 CO 4700418 A1 CO4700418 A1 CO 4700418A1 CO 96019210 A CO96019210 A CO 96019210A CO 96019210 A CO96019210 A CO 96019210A CO 4700418 A1 CO4700418 A1 CO 4700418A1
Authority
CO
Colombia
Prior art keywords
susti
photodescomposition
oxydoles
tides
inhibition
Prior art date
Application number
CO96019210A
Other languages
Spanish (es)
Inventor
Willard C Newlin Jr
Sharon M Laughlin
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CO4700418A1 publication Critical patent/CO4700418A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4883Capsule finishing, e.g. dyeing, aromatising, polishing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Polymerisation Methods In General (AREA)
  • Macromonomer-Based Addition Polymer (AREA)

Abstract

Un procedimiento para inhibir la fotodescomposición de uncompuesto de la fórmula (ver recuadro) y la forma enólica del mismo o una sal de bases farmacéuticamente aceptable del mismo, en la que X es H, Cl o F; Y es H o Cl; y R es bencilo o tienilo, cada uno opcionalmente sustituido con Cl o F; resultando dicha fotodescomposición de una luz que procede de una fuente luminosa, que comprende introducir un medio fotoabsorbente entre dicho compuesto y dicha fuente luminosa.A method of inhibiting photodecomposition of a compound of the formula (see box) and the enolic form thereof or a pharmaceutically acceptable base salt thereof, wherein X is H, Cl or F; Y is H or Cl; and R is benzyl or thienyl, each optionally substituted with Cl or F; said photo-decomposition resulting in a light coming from a light source, which comprises introducing a photo-absorbent medium between said compound and said light source.

CO96019210A 1995-04-24 1996-04-22 INHIBITION OF THE PHOTODESCOMPOSITION OF 2-OXYDOLES 3-SUSTI- TIDES CO4700418A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB1995/000287 WO1996033701A1 (en) 1995-04-24 1995-04-24 Inhibiting photodecomposition of 3-substituted-2-oxindoles

Publications (1)

Publication Number Publication Date
CO4700418A1 true CO4700418A1 (en) 1998-12-29

Family

ID=36997502

Family Applications (1)

Application Number Title Priority Date Filing Date
CO96019210A CO4700418A1 (en) 1995-04-24 1996-04-22 INHIBITION OF THE PHOTODESCOMPOSITION OF 2-OXYDOLES 3-SUSTI- TIDES

Country Status (30)

Country Link
EP (1) EP0827399A1 (en)
JP (1) JPH10506635A (en)
KR (1) KR100189585B1 (en)
CN (1) CN1053667C (en)
AP (1) AP607A (en)
AR (1) AR002728A1 (en)
AU (1) AU692378B2 (en)
BG (1) BG100531A (en)
BR (1) BR9602024A (en)
CO (1) CO4700418A1 (en)
FI (1) FI973988A (en)
HR (1) HRP960194A2 (en)
HU (1) HU216544B (en)
IL (1) IL117969A0 (en)
IS (1) IS4339A (en)
MA (1) MA23848A1 (en)
NO (1) NO961622L (en)
NZ (1) NZ286432A (en)
OA (1) OA10286A (en)
PE (1) PE34397A1 (en)
RO (1) RO113305B1 (en)
RU (1) RU2109510C1 (en)
SG (1) SG64924A1 (en)
SI (1) SI9600133A (en)
SK (1) SK51296A3 (en)
TR (1) TR199600300A2 (en)
UA (1) UA42739C2 (en)
WO (1) WO1996033701A1 (en)
YU (1) YU25096A (en)
ZA (1) ZA963210B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111526730B (en) 2017-12-29 2024-02-23 卡夫食品集团品牌有限责任公司 Improved oxidative stability of oil-in-water emulsions using natural stabilizers

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT59592A (en) * 1990-07-20 1992-06-29 Egyt Gyogyszervegyeszeti Gyar Process for the preparation of solid medical products
TW438798B (en) * 1992-10-07 2001-06-07 Pfizer 3-substituted 2-oxindole-1-carboxamide pharmaceutical compositions

Also Published As

Publication number Publication date
HU216544B (en) 1999-07-28
JPH10506635A (en) 1998-06-30
UA42739C2 (en) 2001-11-15
BG100531A (en) 1997-06-30
HUP9601057A2 (en) 1997-04-28
AP9600787A0 (en) 1996-04-30
KR960037656A (en) 1996-11-19
CN1139110A (en) 1997-01-01
RU2109510C1 (en) 1998-04-27
AU692378B2 (en) 1998-06-04
WO1996033701A1 (en) 1996-10-31
TR199600300A2 (en) 1996-11-21
AR002728A1 (en) 1998-04-29
SI9600133A (en) 1996-10-31
EP0827399A1 (en) 1998-03-11
KR100189585B1 (en) 1999-06-01
BR9602024A (en) 1998-10-06
PE34397A1 (en) 1997-09-29
HUP9601057A3 (en) 1997-05-28
FI973988A0 (en) 1997-10-17
CN1053667C (en) 2000-06-21
ZA963210B (en) 1997-10-23
IS4339A (en) 1996-10-25
YU25096A (en) 1998-08-14
NO961622L (en) 1996-10-25
IL117969A0 (en) 1996-08-04
AU5085196A (en) 1996-11-07
MA23848A1 (en) 1996-12-31
AP607A (en) 1997-08-27
NO961622D0 (en) 1996-04-23
OA10286A (en) 1997-09-19
RO113305B1 (en) 1998-06-30
FI973988A (en) 1997-10-17
NZ286432A (en) 1998-05-27
SK51296A3 (en) 1997-04-09
HRP960194A2 (en) 1998-02-28
HU9601057D0 (en) 1996-06-28
SG64924A1 (en) 1999-05-25

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