CO4700299A1 - DERIVATIVES OF PIPERAZINE, MEDICINES CONTAINING THESE COMPOUNDS, THEIR USE AND PROCEDURE FOR THE PREPARATION - Google Patents

DERIVATIVES OF PIPERAZINE, MEDICINES CONTAINING THESE COMPOUNDS, THEIR USE AND PROCEDURE FOR THE PREPARATION

Info

Publication number
CO4700299A1
CO4700299A1 CO95061206A CO95061206A CO4700299A1 CO 4700299 A1 CO4700299 A1 CO 4700299A1 CO 95061206 A CO95061206 A CO 95061206A CO 95061206 A CO95061206 A CO 95061206A CO 4700299 A1 CO4700299 A1 CO 4700299A1
Authority
CO
Colombia
Prior art keywords
compounds
preparation
piperazine
derivatives
procedure
Prior art date
Application number
CO95061206A
Other languages
Spanish (es)
Inventor
Helmut Pieper
Frank Himmelsbach
Gunter Linz
Brian Guth
Johannes Weisenberg
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of CO4700299A1 publication Critical patent/CO4700299A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A DERIVADOS DE PIPERAZINA DE LA FORMULA GENERAL: FIGURA 1 SUS TAUTOMEROS, SUS ESTEREOISOMEROS, INCLUIDAS SUS MEZCLAS Y SUS SALES, EN PARTICULAR SUS SALES CON ACIDOS O BASES FISIOLOGICAMENTE COMPATIBLES QUE PRESENTAN VALIOSAS PROPIEDADES FARMACOLOGI- CAS, PREFERIBLEMENTE EFECTOS INHIBIDORES DE LA AGREGACION, A MEDICAMENTOS QUE ESTOS COMPUESTOS Y A SU EMPLEO, ASI COMO A PROCEDIMIENTOS PARA SU PREPARACION.THE PRESENT INVENTION REFERS TO PIPERAZINE DERIVATIVES OF THE GENERAL FORMULA: FROM THE AGGREGATION, TO MEDICINES THAT THESE COMPOUNDS AND TO THEIR USE, AS WELL AS PROCEDURES FOR THEIR PREPARATION.

CO95061206A 1994-12-23 1995-12-22 DERIVATIVES OF PIPERAZINE, MEDICINES CONTAINING THESE COMPOUNDS, THEIR USE AND PROCEDURE FOR THE PREPARATION CO4700299A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19944446301 DE4446301A1 (en) 1994-12-23 1994-12-23 New 1-heterocyclyl-piperazine derivs.
DE19526678A DE19526678A1 (en) 1994-12-23 1995-07-21 New heterocyclic substd. piperazine derivs.
DE1995133639 DE19533639A1 (en) 1994-12-23 1995-09-12 Piperazine derivatives, pharmaceutical compositions containing them, their use and processes for their preparation

Publications (1)

Publication Number Publication Date
CO4700299A1 true CO4700299A1 (en) 1998-12-29

Family

ID=6536919

Family Applications (1)

Application Number Title Priority Date Filing Date
CO95061206A CO4700299A1 (en) 1994-12-23 1995-12-22 DERIVATIVES OF PIPERAZINE, MEDICINES CONTAINING THESE COMPOUNDS, THEIR USE AND PROCEDURE FOR THE PREPARATION

Country Status (5)

Country Link
KR (1) KR987000970A (en)
CO (1) CO4700299A1 (en)
DE (3) DE4446301A1 (en)
PE (1) PE63996A1 (en)
YU (1) YU78695A (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6069143A (en) * 1994-12-20 2000-05-30 Smithkline Beecham Corporation Fibrinogen receptor antagonists
US5889006A (en) * 1995-02-23 1999-03-30 Schering Corporation Muscarinic antagonists
US5990107A (en) * 1996-06-28 1999-11-23 Merck & Co., Inc. Fibrinogen receptor antagonist prodrugs
US5854245A (en) * 1996-06-28 1998-12-29 Merck & Co., Inc. Fibrinogen receptor antagonists
AU721130B2 (en) * 1996-06-28 2000-06-22 Merck & Co., Inc. Fibrinogen receptor antagonists
US5932582A (en) * 1996-06-28 1999-08-03 Merck & Co., Inc. Fibrinogen receptor antagonist prodrugs
US5945545A (en) * 1996-12-13 1999-08-31 Merck & Co., Inc. Fibrinogen receptor antagonists
EP1070712A4 (en) * 1998-04-09 2005-01-05 Meiji Seika Kaisha Nitrogen-containing heterocyclic compounds having antiplatelet aggregation effect and medicinal use thereof

Also Published As

Publication number Publication date
DE19533639A1 (en) 1997-03-13
KR987000970A (en) 1998-04-30
PE63996A1 (en) 1997-01-24
DE4446301A1 (en) 1996-06-27
YU78695A (en) 1998-09-18
DE19526678A1 (en) 1997-01-23

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