CO2023011603A2 - Aplicación del inhibidor de apoptosis 5 (api5) para la restitución epitelial - Google Patents
Aplicación del inhibidor de apoptosis 5 (api5) para la restitución epitelialInfo
- Publication number
- CO2023011603A2 CO2023011603A2 CONC2023/0011603A CO2023011603A CO2023011603A2 CO 2023011603 A2 CO2023011603 A2 CO 2023011603A2 CO 2023011603 A CO2023011603 A CO 2023011603A CO 2023011603 A2 CO2023011603 A2 CO 2023011603A2
- Authority
- CO
- Colombia
- Prior art keywords
- api5
- recombinant
- proteins
- application
- apoptosis inhibitor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente descripción proporciona, entre otras cosas, proteínas API5 recombinantes y ácidos nucleicos aislados que las codifican. También se proporcionan vectores que comprenden los ácidos nucleicos y células hospedadoras que comprenden los vectores o ácidos nucleicos que codifican las proteínas API5 recombinantes. Además, se proporcionan composiciones que comprenden dichas proteínas recombinantes, y métodos de uso de estas proteínas recombinantes para la restitución epitelial y el tratamiento de enfermedades y trastornos relacionados.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202163157225P | 2021-03-05 | 2021-03-05 | |
PCT/US2022/019138 WO2022187738A1 (en) | 2021-03-05 | 2022-03-07 | Application of apoptosis inhibitor 5 (api5) for epithelial restitution |
Publications (1)
Publication Number | Publication Date |
---|---|
CO2023011603A2 true CO2023011603A2 (es) | 2023-09-18 |
Family
ID=83154664
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CONC2023/0011603A CO2023011603A2 (es) | 2021-03-05 | 2023-08-31 | Aplicación del inhibidor de apoptosis 5 (api5) para la restitución epitelial |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP4301471A1 (es) |
JP (1) | JP2024509540A (es) |
CN (1) | CN118159569A (es) |
AU (1) | AU2022229921A1 (es) |
BR (1) | BR112023017843A2 (es) |
CA (1) | CA3210274A1 (es) |
CO (1) | CO2023011603A2 (es) |
MX (1) | MX2023010078A (es) |
WO (1) | WO2022187738A1 (es) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8076309B2 (en) * | 2008-04-30 | 2011-12-13 | New York University | USP47 inhibtors and methods to induce apoptosis |
CA2938470C (en) * | 2014-02-17 | 2022-08-30 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Antiapoptotic protein aac-11 derived peptides for the treatment of cancer |
US20160202242A1 (en) * | 2014-12-26 | 2016-07-14 | Nitto Denko Corporation | Cell death-inducing agent, cell growth-inhibiting agent, and pharmaceutical composition for treatment of disease caused by abnormal cell growth |
-
2022
- 2022-03-07 CA CA3210274A patent/CA3210274A1/en active Pending
- 2022-03-07 WO PCT/US2022/019138 patent/WO2022187738A1/en active Application Filing
- 2022-03-07 BR BR112023017843A patent/BR112023017843A2/pt unknown
- 2022-03-07 MX MX2023010078A patent/MX2023010078A/es unknown
- 2022-03-07 EP EP22764216.2A patent/EP4301471A1/en active Pending
- 2022-03-07 AU AU2022229921A patent/AU2022229921A1/en active Pending
- 2022-03-07 JP JP2023553403A patent/JP2024509540A/ja active Pending
- 2022-03-07 CN CN202280019355.8A patent/CN118159569A/zh active Pending
-
2023
- 2023-08-31 CO CONC2023/0011603A patent/CO2023011603A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
EP4301471A1 (en) | 2024-01-10 |
CA3210274A1 (en) | 2022-09-09 |
WO2022187738A1 (en) | 2022-09-09 |
AU2022229921A1 (en) | 2023-09-14 |
JP2024509540A (ja) | 2024-03-04 |
MX2023010078A (es) | 2023-11-09 |
CN118159569A (zh) | 2024-06-07 |
BR112023017843A2 (pt) | 2023-12-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CL2022000300A1 (es) | Muteínas de interleucina 21 y sus usos para tratar tumores sólidos (divisional de la solicitud no. 202000252) | |
NI201800121A (es) | Proteínas de fusión gdf15 y usos de estas | |
MX2020011257A (es) | Ácidos nucleicos recombinantes que codifican una o más proteínas cosméticas para usos estéticos. | |
BR112021022874A2 (pt) | Proteínas de ligação epcam e métodos de uso | |
UY38613A (es) | Inhibidores de la proteína tirosina fosfatasa y mètodos de uso de los mismos | |
ECSP22063238A (es) | Inhibidores de péptidos del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias | |
CO2019002609A2 (es) | Proteínas de unión recombinantes y sus usos | |
AR115389A1 (es) | Anticuerpo antagonista de cd73 | |
CO2020009402A2 (es) | Proteínas de fusión fc il-22 y métodos de uso | |
CO2022001210A2 (es) | Conjugados de il-2 y métodos de uso para tratar enfermedades autoinmunes | |
CO2020003187A2 (es) | Rnai variante | |
EA202092459A1 (ru) | Гибридные белки интерлейкина 12, композиции и способы терапевтического применения, которые их включают | |
CO2022006014A2 (es) | Terapia de tumores sólidos cd70+ utilizando linfocitos t genomodificados dirigidos a cd70 referencia cruzada a solicitudes relacionadas | |
CO2020013050A2 (es) | Enzimas quinureninasa humanas y sus usos | |
CR20170507A (es) | Fusiones de variante iii del receptor de factor de crecimiento epidérmico-mesotelina y métodos para usar los mismos. | |
CO2023011603A2 (es) | Aplicación del inhibidor de apoptosis 5 (api5) para la restitución epitelial | |
MX2020003672A (es) | Proteinas de fusion inmunomoduladora. | |
BR112022006842A2 (pt) | Construtos de igf2 variante | |
CL2020002246A1 (es) | Expresión de proteína de superficie a neumocócica (pspa) | |
BR112023022367A2 (pt) | Anticorpos anti-tigit e métodos de uso dos mesmos | |
BR112022006923A2 (pt) | Polipeptídeos recombinantes para localização celular regulável | |
BR112023003265A2 (pt) | Inibidores de secreção de proteínas | |
CO2020012484A2 (es) | Inhibidores de secreción de proteínas basados en triazaciclododecansulfonamida ("tcd") | |
AR114282A1 (es) | Inhibidores de secreción de proteínas basados en triazaciclododecansulfonamida (“tcd”) | |
AR120358A1 (es) | Proteínas cdkl5 recombinantes, terapia génica y métodos de producción |