CO2017010659A2 - Emulsiones para formulaciones inyectables - Google Patents

Emulsiones para formulaciones inyectables

Info

Publication number
CO2017010659A2
CO2017010659A2 CONC2017/0010659A CO2017010659A CO2017010659A2 CO 2017010659 A2 CO2017010659 A2 CO 2017010659A2 CO 2017010659 A CO2017010659 A CO 2017010659A CO 2017010659 A2 CO2017010659 A2 CO 2017010659A2
Authority
CO
Colombia
Prior art keywords
emulsions
emulsifier
emulsifiers
injectable formulations
vaccine formulations
Prior art date
Application number
CONC2017/0010659A
Other languages
English (en)
Inventor
Edna Fernandes
Roberta Ondei
Original Assignee
Croda Int Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Croda Int Plc filed Critical Croda Int Plc
Publication of CO2017010659A2 publication Critical patent/CO2017010659A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59

Abstract

Emulsionantes para formulaciones de vacuna en emulsiones y uso de una emulsión de agua-en-aceite para formulaciones de vacuna como emulsionante. El emulsionante es un poliol o una poliamina alcoxilados que están opcionalmente terminados con acilo. También se proporciona un método de formación de la formulación de vacuna. Los emulsionantes proporcionan emulsiones que pueden necesitar menos emulsionante que los emulsionantes conocidos y proporcionan emulsiones estables.
CONC2017/0010659A 2015-04-23 2017-10-19 Emulsiones para formulaciones inyectables CO2017010659A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1506948.7A GB201506948D0 (en) 2015-04-23 2015-04-23 Emulsions for injectable formulations
PCT/GB2016/050952 WO2016170302A1 (en) 2015-04-23 2016-04-04 Emulsions for injectable formulations

Publications (1)

Publication Number Publication Date
CO2017010659A2 true CO2017010659A2 (es) 2018-01-05

Family

ID=53488558

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2017/0010659A CO2017010659A2 (es) 2015-04-23 2017-10-19 Emulsiones para formulaciones inyectables

Country Status (10)

Country Link
US (1) US10888614B2 (es)
EP (1) EP3285802B1 (es)
AR (1) AR104196A1 (es)
AU (1) AU2016252222B2 (es)
BR (1) BR112017022701A2 (es)
CO (1) CO2017010659A2 (es)
ES (1) ES2886567T3 (es)
GB (1) GB201506948D0 (es)
HU (1) HUE055659T2 (es)
WO (1) WO2016170302A1 (es)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2649013B1 (fr) * 1989-07-03 1991-10-25 Seppic Sa Vaccins et vecteurs de principes actifs fluides contenant une huile metabolisable
US20060034937A1 (en) 1999-11-23 2006-02-16 Mahesh Patel Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
ES2331058T3 (es) 2001-02-28 2009-12-21 Intervet International Bv Emulsiones de agua en aceite inyectables.
FR2824279B1 (fr) 2001-05-04 2004-05-28 Seppic Sa Emulsion e/h concentree
WO2006061827A1 (en) * 2004-12-06 2006-06-15 Nutralease Ltd. Microemulsion comprising carbamazepine having solubility
CL2008001806A1 (es) * 2007-06-20 2008-09-05 Wyeth Corp Composicion de vacuna en emulsion agua en aceite que comprende un antigeno y un adyuvante en la fase acuosa; y metodo de elaboracion.
GB2485327A (en) 2009-08-12 2012-05-09 Sigmoid Pharma Ltd Immunomodulatory compositions comprising a polymer matrix and an oil phase
ES2688798T3 (es) 2010-03-17 2018-11-07 Croda, Inc. Tensioactivo polimérico

Also Published As

Publication number Publication date
EP3285802A1 (en) 2018-02-28
AU2016252222A1 (en) 2017-10-26
GB201506948D0 (en) 2015-06-10
HUE055659T2 (hu) 2021-12-28
US20180104329A1 (en) 2018-04-19
AR104196A1 (es) 2017-07-05
AU2016252222B2 (en) 2021-07-29
EP3285802B1 (en) 2021-06-16
US10888614B2 (en) 2021-01-12
WO2016170302A1 (en) 2016-10-27
ES2886567T3 (es) 2021-12-20
BR112017022701A2 (pt) 2018-07-17

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