CO2017009515A2 - Análogos de ferruginol como agentes antivirales - Google Patents
Análogos de ferruginol como agentes antiviralesInfo
- Publication number
- CO2017009515A2 CO2017009515A2 CONC2017/0009515A CO2017009515A CO2017009515A2 CO 2017009515 A2 CO2017009515 A2 CO 2017009515A2 CO 2017009515 A CO2017009515 A CO 2017009515A CO 2017009515 A2 CO2017009515 A2 CO 2017009515A2
- Authority
- CO
- Colombia
- Prior art keywords
- ferruginol
- analogs
- antiviral agents
- alkylamide
- stereochemistry
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
- C07C39/17—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings containing other rings in addition to the six-membered aromatic rings, e.g. cyclohexylphenol
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Análogos de Ferruginol como agentes antivirales La presente invención se refiere a un análogo de ferruginol de fórmula (I) en la que R1, R2 R3 y X tienen independientemente el significado siguiente: - R1 es CH2-ftalimido, CH2-succinimido, CH2-maleimido, CH2-NHCOCH3, CH2-NHCOCF3, CHO, CH2OH, (C1-C6)carboxiester, o CH3 y donde R1 tiene cualquier estereoquímica, - R2 es H, OH, F, Cl, Br, NO2, NH2, (C1-C6)alquilamino, di(C1-C6)alquilamino, (C1-C6)alquilamida o di(C1-C6)alquilamida, - R3 es H o OH, - X es H2, O, OH o NOH, donde X puede tener cualquier esteroquímica en el caso apropiado, como cuando es OH, incluyendo cualquier estereoisómero, para su uso como antiviral, especialmente para su uso contra virus envueltos, y de forma especialmente preferida contra el virus del dengue y herpes.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES201530320A ES2586505B1 (es) | 2015-03-12 | 2015-03-12 | Análogos de ferruginol como agentes antivirales |
| PCT/ES2016/070164 WO2016142568A1 (es) | 2015-03-12 | 2016-03-14 | Análogos de ferruginol como agentes antivirales |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO2017009515A2 true CO2017009515A2 (es) | 2018-01-16 |
Family
ID=56879247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CONC2017/0009515A CO2017009515A2 (es) | 2015-03-12 | 2017-09-20 | Análogos de ferruginol como agentes antivirales |
Country Status (3)
| Country | Link |
|---|---|
| CO (1) | CO2017009515A2 (es) |
| ES (1) | ES2586505B1 (es) |
| WO (1) | WO2016142568A1 (es) |
-
2015
- 2015-03-12 ES ES201530320A patent/ES2586505B1/es active Active
-
2016
- 2016-03-14 WO PCT/ES2016/070164 patent/WO2016142568A1/es active Application Filing
-
2017
- 2017-09-20 CO CONC2017/0009515A patent/CO2017009515A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2586505B1 (es) | 2017-07-13 |
| WO2016142568A1 (es) | 2016-09-15 |
| ES2586505A1 (es) | 2016-10-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CR20150337A (es) | Derivados de pirimidinona y su uso en el tratamiento, mejora o prevencion de una enfermedad viral | |
| CL2018000952A1 (es) | Compuestos útiles como inmunomoduladores | |
| CO2018010748A2 (es) | Agentes antivirales contra la hepatitis b | |
| GT201600086A (es) | Pirrolo[12-f][1,2,4]triazinas útiles para tratar infecciones por el virus sincitial respiratorio | |
| CR20160337A (es) | Nuevas heteroarildihidropirimidinas 6-fusionadas para el tratamiento y la profilaxis de la infección por virus de la hepatitis b | |
| CR20160241A (es) | Nuevas dihidroquinolizinonas para el tratamiento y profilaxis de la infección por virus de la hepatitis b | |
| GT201500005A (es) | Composiciones de vacuna para la prevencion contra la infeccion por el virus del dengue | |
| CR20180232A (es) | Macrociclos peptídicos contra acinetobacter baumannii | |
| BR112016028773A2 (pt) | processos para preparação de compostos antivirais | |
| CR20210079A (es) | Sulfamoilarilamidas y su uso como medicamentos para el tratamiento de la hepatitis b | |
| CL2018001192A1 (es) | Análogos de saponina triterpeno | |
| UY35237A (es) | Composiciones que comprenden un compuesto de triazol | |
| BR112017022209A2 (pt) | composição aquosa que compreende éster de ácido omega- aminocarboxílico e álcool graxo e seu uso | |
| UY35238A (es) | Composiciones que comprenden un compuesto de triazol | |
| ECSP17057131A (es) | Desacetoxitubulisina h y análogos de esta | |
| CR20150231A (es) | Composiciones herbicidas de baja volatilidad | |
| DOP2011000268A (es) | Vacuna inactivada del virus del dengue con un adjuvante libre de aluminio | |
| BR112015027432A2 (pt) | 3-(4-isobutil-2-metilfenil)propanal como ingrediente de perfume | |
| MX2012013564A (es) | Composicion de pantalla solar. | |
| BR112017002478A2 (pt) | aminas com baixo teor de voc como um componente surfactante em dispersões | |
| UY35446A (es) | 2?((4?AMINO?3?(3?FLUOR?5?HIDROXIFENIL)?1H?PIRAZOLO[3,4?D]PIRIMIDIN?1?IL)METIL)?5?(3?(2?(2?METOXIETOXI)ETOXI)PROP?1?IN?1?IL)?3?(2?(TRIFLUORMETIL)BENCIL)QUINAZOLIN?4(3H)?ONA COMO INHIBIDOR DUAL DE PI3K d/g | |
| BR112013020719A2 (pt) | composições de derivados de bimatoprost tipo éster e métodos | |
| GT201500247A (es) | Imidazopiridazinas sustituidas | |
| ECSP14004595A (es) | 2-tiopirimidinonas | |
| BR112017004197A2 (pt) | composições de vacina contra doenças do vírus da dengue |