CO2017007322A1 - Hard acid-resistant capsules with low content of gelling aids - Google Patents
Hard acid-resistant capsules with low content of gelling aidsInfo
- Publication number
- CO2017007322A1 CO2017007322A1 CONC2017/0007322A CO2017007322A CO2017007322A1 CO 2017007322 A1 CO2017007322 A1 CO 2017007322A1 CO 2017007322 A CO2017007322 A CO 2017007322A CO 2017007322 A1 CO2017007322 A1 CO 2017007322A1
- Authority
- CO
- Colombia
- Prior art keywords
- range
- mixture
- gelling agents
- polymer
- gellana
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención pertenece al campo farmacéutico; revela una cápsula dura para administración oral con propiedades ácido-resistentes, compuesta por un polímero principal de celulosa o gelatina, dispersantes y plastificantes, y por una mezcla de agentes gelificantes en proporciones mínimas, apta para transportar productos farmacéuticos, veterinarios, nutracéuticos y suplementos dietarios. El polímero principal se selecciona del grupo de las celulosas, preferiblemente hipromelosa, carboximetilcelulosa, o del grupo de las gelatinas, preferiblemente de carnaza mientras que la mezcla de agentes gelificantes puede comprender gomas del tipo gellana, guar, tragacanto, carrageninas, agar, alginato y peptina, con preferencia por una combinación de goma gellana y kappa carragenina. Adicionalmente, la cápsula puede comprender colorantes, edulcorantes y saborizantes. En su realización preferida, la cápsula dura está basada en un polímero de celulosa del tipo hipromelosa, en un rango comprendido entre 80% y 95 VD, un agente dispersante en un rango comprendido entre el 0.05 % y 2%, un plastificante en un rango comprendido entre el 1% y 5%, y una mezcla de agentes gelificantes en un rango comprendido entre el 004% y 3.5 %.The present invention belongs to the pharmaceutical field; It reveals a hard capsule for oral administration with acid-resistant properties, composed of a main cellulose or gelatin polymer, dispersants and plasticizers, and a mixture of gelling agents in minimum proportions, suitable for transporting pharmaceutical, veterinary, nutraceutical and dietary supplements . The main polymer is selected from the group of celluloses, preferably hypromellose, carboxymethylcellulose, or from the group of gelatins, preferably from carnaza while the mixture of gelling agents can comprise gellana, guar, tragacanth, carrageenan, agar, alginate and gums. peptin, preferably by a combination of gellana gum and kappa carrageenan. Additionally, the capsule may comprise colorants, sweeteners and flavorings. In its preferred embodiment, the hard capsule is based on a cellulose polymer of the hypromellose type, in a range between 80% and 95V, a dispersing agent in a range between 0.05% and 2%, a plasticizer in a range between 1% and 5%, and a mixture of gelling agents in a range between 004% and 3.5%.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CONC2017/0007322A CO2017007322A1 (en) | 2017-07-24 | 2017-07-24 | Hard acid-resistant capsules with low content of gelling aids |
| PCT/CO2018/000016 WO2019020134A2 (en) | 2017-07-24 | 2018-07-23 | Hard, acid-resistant capsules having a low gelling adjuvant content |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CONC2017/0007322A CO2017007322A1 (en) | 2017-07-24 | 2017-07-24 | Hard acid-resistant capsules with low content of gelling aids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO2017007322A1 true CO2017007322A1 (en) | 2019-01-31 |
Family
ID=65040392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CONC2017/0007322A CO2017007322A1 (en) | 2017-07-24 | 2017-07-24 | Hard acid-resistant capsules with low content of gelling aids |
Country Status (2)
| Country | Link |
|---|---|
| CO (1) | CO2017007322A1 (en) |
| WO (1) | WO2019020134A2 (en) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003011257A1 (en) * | 2001-08-01 | 2003-02-13 | Jasjit Singh | Composition and process the manufacture of soluble containers with improved gel-strength |
| WO2007098612A1 (en) * | 2006-03-02 | 2007-09-07 | Laboratoires Mauves Inc. | Gastric acid resistant gelatin capsule composition and method for producing same |
| AU2010299527A1 (en) * | 2009-09-24 | 2012-04-19 | Capsugel Belgium Nv | Acid resistant capsules |
| CA2870134C (en) * | 2012-05-02 | 2020-04-28 | Capsugel France SAS | Aqueous dispersions of hydroxypropyl methylcellulose acetate succinate (hpmcas) |
| CN104288120B (en) * | 2014-10-16 | 2017-01-18 | 绍兴康可胶囊有限公司 | Enteric-coated plant cellulose hard empty capsules and preparation method thereof |
-
2017
- 2017-07-24 CO CONC2017/0007322A patent/CO2017007322A1/en unknown
-
2018
- 2018-07-23 WO PCT/CO2018/000016 patent/WO2019020134A2/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019020134A3 (en) | 2019-03-28 |
| WO2019020134A2 (en) | 2019-01-31 |
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