CN103520132A - Deformable soft capsule - Google Patents

Deformable soft capsule Download PDF

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Publication number
CN103520132A
CN103520132A CN201310501261.7A CN201310501261A CN103520132A CN 103520132 A CN103520132 A CN 103520132A CN 201310501261 A CN201310501261 A CN 201310501261A CN 103520132 A CN103520132 A CN 103520132A
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CN
China
Prior art keywords
soft capsule
softgel shell
sealing coat
deformable soft
plasticizer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201310501261.7A
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Chinese (zh)
Inventor
宋正权
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanjing Qinhuai Hospital
Original Assignee
Nanjing Qinhuai Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanjing Qinhuai Hospital filed Critical Nanjing Qinhuai Hospital
Priority to CN201310501261.7A priority Critical patent/CN103520132A/en
Publication of CN103520132A publication Critical patent/CN103520132A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a deformable soft capsule. The deformable soft capsule comprises a capsule shell (1) and a medicine core (2) contained in the capsule shell (1) and is characterized in that the shape of the capsule shell (1) has the plasticity. According to the deformable soft capsule, due to the design of the plastic capsule shell and an isolating layer, the shape of the soft capsule can be changed, a medicine user can change the shape of the soft capsule at will according to the self condition of an individual, and the taking compliance of the soft capsule is improved; due to the design of the isolating layer, the capsule shell is prevented from being dissolved by the medicine core.

Description

A kind of deformable soft capsule
Technical field
The present invention relates to a kind of deformable soft capsule, belong to technical field of medicine.
Background technology
Current soft capsule is generally the soft capsule of solid shape, be generally fixing ellipse or strip, can not change shape, sometimes, for different pill takers, there will be dosage form excessive, take poor compliance, the phenomenon that is difficult for swallowing, compliance while taking in order to improve soft capsule, the invention provides a kind of different pill taker and can arbitrarily change according to individual self-condition the deformable soft capsule of soft capsule shape.
Summary of the invention
Technical problem to be solved by this invention is that a kind of deformable soft capsule is provided.
For solving the problems of the technologies described above, the technical solution used in the present invention is:
A soft capsule, comprising: softgel shell and be included in the medicated core in described softgel shell, is characterized in that: the shape of described softgel shell has plasticity.
The composition of described softgel shell comprises gelatin, plasticizer and water, and the weight ratio of gelatin dry product, plasticizer dry product and water is 1:2.0 ~ 2.5:1.
Described plasticizer is the two mixture or propylene glycol of glycerol, sorbitol, glycerol and sorbitol.
Between described softgel shell and medicated core, be provided with for avoiding described medicated core to dissolve the sealing coat of described softgel shell.
Described sealing coat is plasticity stomach dissolution type sealing coat or plasticity erosion type sealing coat, and the composition of described sealing coat comprises the mixture of one or more and described plasticizer and water in hyprolose, methylcellulose, cellulose, sodium alginate, guar gum, chitosan, polyvidone, stearic acid, babassu sodium, stearyl alcohol.
A kind of deformable soft capsule provided by the invention, the setting of plastic softgel shell and sealing coat, can guarantee the change of the shape of soft capsule, pill taker can arbitrarily change soft capsule shape according to individual self-condition, thereby the compliance of taking that improves soft capsule, arranging of described sealing coat can avoid described medicated core to dissolve described softgel shell.
Accompanying drawing explanation
Fig. 1 is structural representation of the present invention.
The specific embodiment
Below in conjunction with accompanying drawing, the present invention is further described.
As shown in Figure 1, a kind of deformable soft capsule, comprising: softgel shell 1 and be included in the medicated core 2 in described softgel shell 1, is characterized in that: the shape of described softgel shell 1 has plasticity.
The composition of described softgel shell 1 comprises gelatin, plasticizer and water, and the weight ratio of gelatin dry product, plasticizer dry product and water is 1:2.0 ~ 2.5:1.
Described plasticizer is the two mixture or propylene glycol of glycerol, sorbitol, glycerol and sorbitol.
Between described softgel shell 1 and medicated core 2, be provided with for avoiding described medicated core 2 to dissolve the sealing coat 3 of described softgel shell 1.
Described sealing coat 3 is plasticity stomach dissolution type sealing coat or plasticity erosion type sealing coat, and the composition of described sealing coat 3 comprises the mixture of one or more and described plasticizer and water in hyprolose, methylcellulose, cellulose, sodium alginate, guar gum, chitosan, polyvidone, stearic acid, babassu sodium, stearyl alcohol.
The above is only the preferred embodiment of the present invention; be noted that for those skilled in the art; under the premise without departing from the principles of the invention, can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.

Claims (5)

1. a deformable soft capsule, comprising: softgel shell (1) and be included in the medicated core (2) in described softgel shell (1), is characterized in that: the shape of described softgel shell (1) has plasticity.
2. a kind of deformable soft capsule according to claim 1, is characterized in that: the composition of described softgel shell (1) comprises gelatin, plasticizer and water, and the weight ratio of gelatin dry product, plasticizer dry product and water is 1:2.0 ~ 2.5:1.
3. a kind of deformable soft capsule according to claim 2, is characterized in that: described plasticizer is the two mixture or propylene glycol of glycerol, sorbitol, glycerol and sorbitol.
4. a kind of deformable soft capsule according to claim 1, is characterized in that: between described softgel shell (1) and medicated core (2), be provided with for avoiding described medicated core (2) to dissolve the sealing coat (3) of described softgel shell (1).
5. a kind of deformable soft capsule according to claim 4, it is characterized in that: described sealing coat (3) is plasticity stomach dissolution type sealing coat or plasticity erosion type sealing coat, the composition of described sealing coat (3) comprises the mixture of one or more and described plasticizer and water in hyprolose, methylcellulose, cellulose, sodium alginate, guar gum, chitosan, polyvidone, stearic acid, babassu sodium, stearyl alcohol.
CN201310501261.7A 2013-10-23 2013-10-23 Deformable soft capsule Pending CN103520132A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310501261.7A CN103520132A (en) 2013-10-23 2013-10-23 Deformable soft capsule

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310501261.7A CN103520132A (en) 2013-10-23 2013-10-23 Deformable soft capsule

Publications (1)

Publication Number Publication Date
CN103520132A true CN103520132A (en) 2014-01-22

Family

ID=49922723

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201310501261.7A Pending CN103520132A (en) 2013-10-23 2013-10-23 Deformable soft capsule

Country Status (1)

Country Link
CN (1) CN103520132A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115721627A (en) * 2022-11-10 2023-03-03 南通华山药业有限公司 Motherwort soft capsule and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115721627A (en) * 2022-11-10 2023-03-03 南通华山药业有限公司 Motherwort soft capsule and preparation method thereof

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PB01 Publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20140122

WD01 Invention patent application deemed withdrawn after publication