CN86100247A - Multifunctional program-controlled heart stimulator - Google Patents
Multifunctional program-controlled heart stimulator Download PDFInfo
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- CN86100247A CN86100247A CN 86100247 CN86100247A CN86100247A CN 86100247 A CN86100247 A CN 86100247A CN 86100247 CN86100247 CN 86100247 CN 86100247 A CN86100247 A CN 86100247A CN 86100247 A CN86100247 A CN 86100247A
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- circuit
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- electrocardio
- time delay
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Abstract
Existing program-controlled heart stimulator generally is traumatic and does not have the tachycardia device of identification automatically.The present invention utilizes the pulse switch technology, has designed the boost pulse after-potential and suppress circuit in instrument, can extract electrocardio P ripple signal through esophagus, has realized that the noinvasive atrium of getting ill from overeating is synchronous.And this instrument has automatic identification tachycardia function, has clinical use value.
The present invention has the program control pulse output form of multiple function, can realize multi-functional heart electric stimulating, provides good appointed condition for carrying out cardiac electrophysiology stud and treating tachycardia.
Description
The invention belongs to medical electronic apparatus.
Utilize program-controlled heart stimulator can carry out active and measure, disclose ARR mechanism,, control so that the doctor executes to the ill for routine electrocardiogram provides definite data and supplementary notes to the electric-physiology parameter at each position of heart of patient.Secondly find under study for action that the arrhythmia of many types can directly be treated with electric pulse stimulation,, often only need the stimulation of 1 to 2 electric pulse just can stop immediately, played the incomparable effect of medicine the tachycardia of serious symptom.So program-controlled heart stimulator the electrophysiologic study of heart and clinical in have important effect.
Practical both at home and abroad at present various program-controlled heart stimulators are most of to take out electrocardiosignal through vein, also is traumatic.Do not have the tachycardic device of automatic identification in addition.So electrophysiologic study has been brought inconvenience, has also brought great misery to the patient.As U.S. Medtronic 5325 type program-controlled heart stimulators.
Realize that no wound ground extracts electrocardiosignal, promptly extract electrocardio P ripple signal from esophagus, so that cardiac stimulation and atrium are synchronous, its main difficulty is: owing to need reach 40 volts more than the voltage through the general maximum of pulse voltage amplitude of esophagus cardiac stimulus, and esophagus electrocardio P ripple voltage of signals amplitude general about several millivolts of zero points only.Therefore after boost pulse sends, its after-potential will seriously block the electrocardio amplifying circuit of back, so that make the interior electrocardiosignal of quite a while behind the boost pulse be submerged and can not take out.
The problem that the present invention is directed to above-mentioned existence has designed a kind of novel multifunctional program-controlled heart stimulator.
Fig. 1 to Fig. 4 is a principle schematic of the present invention, wherein:
Fig. 1 is a circuit general diagram of the present invention.Wherein 1 for the boost pulse after-potential suppress circuit, 2 for the electrocardio amplification and rectification circuit, 3 for the tachycardia automatic identification circuit, 4 for the control gate circuit, 5 for clock circuit, 6 for counter circuit, 7 for comparator circuit, 8 for register circuit, 9 for comment a yard display circuit, 10 for program control pulse generating circuit, 11 for add, down control circuit, 12 is panel control and auxiliary circuit, 13 is an electrode.
Fig. 2 suppresses the schematic diagram of circuit 1 for the boost pulse after-potential.S wherein
1, S
2For on-off circuit, 14,15,16 is the time delay control circuit.
Fig. 3 suppresses the switching time delay timing waveform of circuit 1 for the boost pulse after-potential.
Fig. 4 is the overrun schematic diagram of automatic identification circuit 3 of electrocardio.Wherein 17 is integrated oscillator circuit, and resistance R, capacitor C are external timing element, the S of integrated oscillator circuit 17
3, S
4For on-off circuit, D are diode, V
DDBe supply voltage, resistance R
1, capacitor C
1It is a time delay control circuit.
Principles illustrated of the present invention is as follows:
As can be seen from Figure 1, to take out through esophagus or transvenous electrocardiosignal by electrode 13, input stimulus pulse after-potential suppresses circuit 1(when boost pulse, this circuit can suppress the influence of boost pulse after-potential to electrocardiosignal effectively, its principle will be stated below in addition) after be admitted to electrocardio amplification and rectification circuit 2, exporting pulse signal to the principle of tachycardia automatic identification circuit 3(this circuit corresponding with electrocardio P ripple signal will state below in addition), tachycardia takes place and then gives an order and open control gate circuit 4 in identification circuit 3 as think.This gate circuit 4 promptly allows 5 pairs of counter circuits 6 of clock circuit to count, and when the number (presetting by panel control circuit) of the number of enumerator and register circuit 8 when equating, comparator circuit 7 is just exported a coincidence pulse.This coincidence pulse has four effects.(1) delivers to program control pulse generating circuit 10 and after shaping, power amplification, swash heart, stop tachycardic purpose to reach as boost pulse S deburring.(2) by add, down control circuit 11 makes register circuit 8 presets number and advance one or move back one automatically, to wait for comparison next time.(3) make counter circuit 6 zero clearings, to prepare to receive clock signal next time.(4) control gate circuit 4 is closed.
If can not stop electrocardio after the coincidence pulse output overruns, the tachycardia electrocardiosignal that then recurs continues to be identified circuit 3 and discerns, open control gate circuit 4 again, clock circuit 5 is counted counter circuit 6 again, and compare with the number of next register circuit 8 constantly, export a coincidence pulse once more.Constantly scan the deburring of output coincidence pulse forward or backward with certain rate of change so again and again and swash heart, one finds some appropriate moment surely, and the coincidence pulse of output can stop tachycardia just.At this moment, be stop tachycardic " the window time " by the number of commenting the register circuit 8 that yard display circuit 9 shows.Also be the interval that is identified as between tachycardic electrocardiosignal P wave impulse and the boost pulse.
Overrun when stopping when aroused in interest, recover normal electrocardiosignal and can not be identified circuit 3 and discern, then control gate circuit 4 just is in closed condition always, also just no longer includes coincidence pulse and exports.
The principle of tachycardia automatic identification circuit 3 can be described by Fig. 4.Wherein integrated oscillator circuit 17 is the 4E318 integrated oscillator circuit that adopts Fudan University's e-factory to produce.Its frequency of oscillation is by external timing element resistance R and capacitor C decision.This integrated oscillator circuit 17 has such function: when on external timing element R, C and when connecing a switch, if the frequency of switching signal is higher than frequency of oscillation, then agitator quits work, agitator output V
r' be in high potential.When the frequency of switching signal was lower than frequency of oscillation, then agitator was exported the undersuing of certain frequency.
So send into as can be seen from Figure 4, the on-off circuit S of this circuit in the electrocardio P wave impulse of big shaping circuit 2 outputs of careful tele-release
3The time, if the frequency of electrocardio P wave pulse signal is lower than frequency of oscillation (tachycardia does not promptly take place yet) agitator work this moment, V
rThe negative pulse of ' output certain frequency is exported by diode D coupling.But as long as the time constant of external timing element R, the C of integrated oscillator circuit 17 is significantly smaller than time delay control circuit R
1, C
1Time constant, capacitor C then
1Also have little time by supply voltage V
DDCharging just will be by the output transistor discharge of diode D and oscillating circuit 17 inside, so outfan V
rJust be in electronegative potential all the time, thus on-off circuit S
4All the time be in off-state, then electrocardio P wave pulse signal just can not pass through switch S
4Output.Overrun when taking place when aroused in interest, promptly the frequency of electrocardio P wave pulse signal is higher than frequency of oscillation, and this moment, oscillating circuit 17 quit work V
r' be in high potential, then diode D ends, V
rAlso be in high potential, on-off circuit S
4Be in opening, electrocardio P wave pulse signal is by on-off circuit S
4Output.
From Fig. 4 also as can be known, after tachycardic electrocardio P ripple signal quits work oscillating circuit 17, on-off circuit S
4Be not to open immediately, but will pass through regular hour (V
DDPass through resistance R
1To capacitor C
1The time of charging) just can make V
rBe in high potential, thereby open on-off circuit S
4Also promptly have only the frequency when electrocardio P wave pulse signal to be higher than frequency of oscillation and will to continue the regular hour, identification circuit thinks that just tachycardia takes place.The actual desirable R of the present invention
1, C
1Time constant be 10 seconds.
The boost pulse after-potential suppresses the principle of circuit 1 can be described by Fig. 2 and Fig. 3.As can be seen from Figure 2, when coincidence pulse produces, program control pulse generating circuit 10 output pulse S, this pulse through three time delay control circuits 14,15,16 respectively to electrode 13 and on-off circuit S
1And S
2Time delay control circuit and switch S
1And S
2Pulse sequence as shown in Figure 3.The pulse S of program control pulse generating circuit 10 outputs produces the B pulse by time delay control circuit 15 and makes S
1Closure is sent the C pulse by circuit 16 and is made S
2Disconnect, by circuit 14 time-delay t
1The back produces the A pulse by the sharp heart of electrode 13 deburrings constantly.Wherein the width of A pulse is τ, and the width of B pulse is S
1The closed duration is τ
1, the width of C pulse is S
2The duration that disconnects is τ
2, and design the time makes τ
2>τ
1>τ.As shown in Figure 3, when A impulse action during in heart, S
1Be in and close, S
2Be in off-state, this situation has promptly stoped the effect of cardiac stimulation pulse to electrocardio amplifying circuit 2.Simultaneously also as can be known, work as τ by Fig. 3
2During end, on-off circuit S
4Be not to recover closed condition immediately, but will be t the time
2Slow process just recover to close, This move is finished by time delay control circuit 16, it can be avoided because S
2Close suddenly and make identification circuit 3 misoperations.
Panel control and auxiliary circuit 12 can be finished a series of function selecting and parameter setting and demonstration.Adjusting as the boost pulse voltage amplitude, the selection of boost pulse combining form, the number of register circuit 8 presets, the setting of scan control forward or backward, the setting of automatic or manual identification (when artificial cognition, makes that promptly identification circuit 3 is inoperative, allows electrocardio P wave pulse signal directly send into control gate circuit 4, and make control gate circuit 4 be in open mode always, can directly be controlled by panel and send various forms of boost pulses this moment) or the like.
The present invention has the programmed electrical stimulation pulse output form of several functions owing to considered the various situations that actual electrical physiological Study and clinical practice use, and can carry out multi-functional heart electric stimulating, as hypervelocity suppress, inferior speed competition, win program control morning stimulation, in pairs reach rightPacing stimulation, the short battle array stimulation etc. of bursting. And the present invention can suppress the boost pulse afterpotential effectively to extracting the impact of esophagus electrocardio P ripple signal, has realized that no wound esophagus atrium stimulates synchronously. Simultaneously owing to having the tachycardia automatic identification equipment, so have clinical use value.
The present invention provides good appointed condition for carrying out cardiac electrophysiology stud and treating tachycardia.
Claims (3)
1, a kind of by electrocardio amplification and rectification circuit 2.Control gate circuit 4.Clock circuit 5.Counter circuit 6.Comparator circuit 7.Register circuit 8.Comment yard display circuit 9.Program control pulse generating circuit 10.Add-subtract control circuit 11.Panel control and auxiliary circuit 12.The multifunctional program-controlled heart of forming with electrode 13 irritates instrument, it is characterized in that it also comprises following parts:
A) boost pulse after-potential inhibition circuit 1 this circuit of being made up of some on-off circuits and time delay control circuit is connected between electrode 13 and the electrocardio amplification and rectification circuit 2.
B) be the tachycardia identification circuit 3 that external R, C integrated oscillator circuit 17 and some on-off circuits and time delay control circuit are formed by timing element.This circuit is connected between electrocardio amplification and rectification circuit 2 and the control gate circuit 4.
2, multifunctional program-controlled heart stimulator according to claim 1 is characterized in that above-mentioned boost pulse after-potential suppresses circuit 1 and is made up of two on-off circuit S1, S2 and three time delay control circuits 14,15,16.The sequential of its switch time and time delay is: the pulse S that program control pulse generating circuit sends produces the B pulse by time delay control circuit 15 and makes the S1 closure, produces the C pulse by circuit 16 S2 is disconnected, and postpones t by circuit 14 simultaneously
1The back produces the A pulse by the sharp heart of electrode 13 deburrings constantly.Wherein the width of A pulse is τ, the width of B pulse, and promptly the duration of S1 closure is τ
1, the width of C pulse, i.e. the duration of S2 disconnection is τ
2, and τ
2>τ
1>τ.Work as τ
2After the end, S
2To it be t in the elapsed time
2Slow process just recover closed.
3,, it is characterized in that two on-off circuit S are arranged in the above-mentioned tachycardia identification circuit 3 according to claim 1,2 described multifunctional program-controlled heart stimulators
3And S
4, the time delay control circuit in the circuit 3 is resistance R
1And capacitor C
1The timing circuit of forming.S wherein
3Connect with external R, the C timing Yuan spare And of above-mentioned integrated oscillator circuit 17, its switching signal is an electrocardio P ripple reshaping signal.R
1, C
1The timing circuit output of forming is as S
4Switching signal, electrocardio P ripple reshaping signal is as S
4Input/output signal.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 86100247 CN86100247A (en) | 1986-01-03 | 1986-01-03 | Multifunctional program-controlled heart stimulator |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 86100247 CN86100247A (en) | 1986-01-03 | 1986-01-03 | Multifunctional program-controlled heart stimulator |
Publications (1)
Publication Number | Publication Date |
---|---|
CN86100247A true CN86100247A (en) | 1987-07-15 |
Family
ID=4800936
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 86100247 Pending CN86100247A (en) | 1986-01-03 | 1986-01-03 | Multifunctional program-controlled heart stimulator |
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CN (1) | CN86100247A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103415320A (en) * | 2011-02-01 | 2013-11-27 | 布里格姆女子医院有限公司 | System and method for cardiac resychronization therapy control parameter generation using ventricular activation simulation and surface ECG registration |
-
1986
- 1986-01-03 CN CN 86100247 patent/CN86100247A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103415320A (en) * | 2011-02-01 | 2013-11-27 | 布里格姆女子医院有限公司 | System and method for cardiac resychronization therapy control parameter generation using ventricular activation simulation and surface ECG registration |
CN103415320B (en) * | 2011-02-01 | 2016-08-10 | 布里格姆女子医院有限公司 | Use ventricular activation simulation and body surface ECG record to carry out cardiac resynchronization therapy and control the System and method for that parameter generates |
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