CN2927678Y - Cage suitable for housing laboratory animals in isolation and related ventilation system - Google Patents
Cage suitable for housing laboratory animals in isolation and related ventilation system Download PDFInfo
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- CN2927678Y CN2927678Y CNU2005900000260U CN200590000026U CN2927678Y CN 2927678 Y CN2927678 Y CN 2927678Y CN U2005900000260 U CNU2005900000260 U CN U2005900000260U CN 200590000026 U CN200590000026 U CN 200590000026U CN 2927678 Y CN2927678 Y CN 2927678Y
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- cage
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- 238000010171 animal model Methods 0.000 title claims abstract description 21
- 238000009423 ventilation Methods 0.000 title claims abstract description 14
- 238000002955 isolation Methods 0.000 title description 3
- 238000011144 upstream manufacturing Methods 0.000 claims abstract description 24
- 238000001914 filtration Methods 0.000 claims abstract description 3
- 238000007789 sealing Methods 0.000 claims description 18
- 230000000740 bleeding effect Effects 0.000 claims description 16
- 208000015181 infectious disease Diseases 0.000 claims description 13
- 239000000463 material Substances 0.000 claims description 9
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- 238000007599 discharging Methods 0.000 claims description 6
- 239000004033 plastic Substances 0.000 claims description 6
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims description 5
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Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
- A01K1/03—Housing for domestic or laboratory animals
- A01K1/031—Cages for laboratory animals; Cages for measuring metabolism of animals
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- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Clinical Laboratory Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Housing For Livestock And Birds (AREA)
- Accommodation For Nursing Or Treatment Tables (AREA)
Abstract
The cage for laboratory animals according to the invention comprises: an inlet valve and an outlet valve respectively capable of allowing air to enter into and exit from the cage; an external casing capable of separating, essentially sealed against leakages of air, the environment inside the casing itself, and which is downstream from the inlet valve and upstream from the one outlet valve, form the environment outside it. The exiting air is purified by means of a filtration system capable of containing the majority of the infective agents, and placed upstream from the outlet valve. The external casing is composed of two half-shells between which an airtight seal with U section is interposed. The invention also relates to the ventilation system to ventilate the cage; such system is equipped with a ventilator unit solely sucking or solely blowing.
Description
Technical field:
The utility model relates to cage tool a kind of and the ccontaining laboratory animal that external environment is isolated, and ventilating system.
Background technology:
Now, in order to be biological safety level 3 (BSL3 with being placed on level of security, be a kind of in order to study those by sucking the source of infection of propagating fatal disease, as severe acute respiratory syndrome (SARS) and West Nile Virus, system) the Animal Experimental Study source of infection, " spacer assembly " is used, this spacer assembly is the airtight container that is isolated from the outside in essence, usually air pressure wherein hangs down a bit than extraneous, and laboratory animal is placed in wherein; Breadboard staff contacts laboratory animal by the oversleeve in the xegregating unit with elastomeric glove, and these oversleeves and gloves are also sealed within the equipment, in case possible air and source of infection leak internally.
Yet do experiment for the laboratory animal of low risk factor, dissimilar stand alone type ventilation cage tools (IVC) are widely used: compare the advantage that these cages have multiple important man-made environment to transform with xegregating unit; But up to now, going back neither one stand alone type ventilation cage tool can separate external environment condition according to biological safety level 3 or same levels with inner.
The purpose of this utility model provides a kind of free-standing ventilation cage tool for laboratory animal exactly, and the ventilating system of this cage tool has better sealing than known ventilation cage system, control source of infection and isolated external environment condition characteristic.
The utility model content:
Based on the realization of the purpose of first aspect of the present utility model be to use be suitable for ccontaining laboratory animal the cage tool, described cage tool comprises :-at least one can allow air to enter the intake valve of described cage tool inner loop;
-at least one can allow air to be discharged into the air bleeding valve of external environment condition from cage tool inside;
-one sealed outer cover to avoid air to leak, it can separate environment in the cover with the cover external environment, environment is positioned at the downstream of at least one intake valve and the upstream of at least one air bleeding valve in the cover body, and outer cover also/maybe can limit any source of infection at the described downstream of at least one intake valve and the upstream environment of at least one air bleeding valve of being arranged in.
For second aspect of the present utility model, the realization of this purpose is that described system comprises by the ventilating system of the cage tool that is used for laboratory animal:
-a plurality of cages, each can hold at least one cage tool, and its cage tool can ccontaining in order one or many laboratory animal;
-one air distribution loop can suck air from the external world, is transported in each cage tool that is embedded on the cage, and discharges from described cage tool.
This system features is that it also comprises pneumatic first-born growing up to be a useful person, and it can be from upstream to the downstream suck air by described distribution loop separately, or is from upstream to the downstream drain air by described distribution loop individually.
By to the detailed description of following non-limiting example and with reference to accompanying drawing, advantage of the present utility model to those skilled in the art is more obvious.
Description of drawings:
Fig. 1 shows the end view based on an embodiment of the independent ventilation cage tool of the bright first aspect of we;
Fig. 2 shows the side sectional view of cage tool among Fig. 1;
Fig. 3 shows the perspective view of the lid of cage tool among Fig. 1;
Fig. 4 shows the cross sectional representation of the two and half shells edge of cage tool among Fig. 1 in conjunction with the gas tight seal circle on limit;
Fig. 4 A shows the cross sectional representation at the gas tight seal circle abutment of cage tool among Fig. 1, and wherein the gas tight seal circle among Fig. 4 is in deformation state;
Fig. 5 shows that the cage tool is along the sectional view of ' locked ' zone vertical plane direction among Fig. 1;
Fig. 6 shows the lock Connection Element of cage tool among Fig. 1 and the perspective view of corresponding lock/unlock device;
Fig. 7 shows the partial sectional view of the air bleeding valve of cage tool among Fig. 1;
Fig. 8 shows that the cage tool is along the internal negative pressure/superpressure indicating device partial sectional view of vertical plane among Fig. 1;
Fig. 9 shows the schematic diagram based on the cage tool ventilation circulation preferred embodiment that is used for laboratory animal of the utility model second aspect;
Figure 10 and 11 shows that one is used for Fig. 9 and is used for providing and discharge two of interface of ventilating system of air partial cross-sectional cut-away view longitudinally to Fig. 1 cage tool, and two figure represent respectively that interface is in and close and open mode;
Figure 12 shows another form of Fig. 1, and it has given prominence to slide holder and slide rail, and partial enlarged drawing;
Figure 13 A and 13B show the change shape schematic diagram of the restraint zone of Fig. 1;
The thin portion of restraint zone among Figure 14 A and 14B demonstration 13A and the 13B is along T-T direction cross sectional representation, and they represent that respectively fastening hook spare is in the state that catches on and open respectively.
Embodiment:
According to first aspect of the present utility model, Fig. 1-the 8th, the preferred embodiment about a unrestriced independent ventilation cage tool totally is designated 100.This cage tool be equipped with one can be so that air be discharged to the air bleeding valve 2 of the downstream branch of described air distribution loop from cage tool inside so that enter the air intake valve 1 (Fig. 1-3) of cage tool and one from for example air of air distribution loop.Intake valve 1 and air bleeding valve 2 preferred one place the lid 8 of cage tool.
The cage tool defines inner space 3 (Fig. 2), and one or more laboratory animal (for example squirrel, small white mouse and cavy) can be by wherein ccontaining.
According to first characteristic of the present utility model, the cage tool also comprises an outer cover 4 (Fig. 2), it can separate or just essence be the environment that seals the cover between the upstream of the downstream that is positioned at intake valve 1 and air bleeding valve 2, or under any circumstance, can isolate the potential source of infection that is arranged in cover, for example bacterium and virus; Outer cover 4 is plastic housing in the present embodiment, it promptly can be with all infected or do not have the laboratory animal that infects, or all or part of object in the cage tool, potential or in cage tool regular maintenance and cleaning, needed processed material by zoogenous material or residual food or excreta and those usually, seal and isolation with external environment: under this situation, the experimenter has to open the cage tool and touches these infected object and materials, can avoid by this method or reduce significantly infecting the probability of giving experimenter oneself.
The cage of being made by steel wire or sheet metal or plastic material 5, one of injection well downhole flow regulators of the inside of outer cover 4 preferred disposition 6 and one can filter the filter 7 of the entrained pathogene of most of air of discharging from outer cover at least.Such filter can be that a highly effective particle air cleaner (HEPA) or other meet 4 grades or 5 grades of absolute filters of ISO146441.1 standard, an or M2.5 or M3.5 level highly effective particle air cleaner that meets Federal Specification 209E: air passed through after this filter was indicated the filtration that allows every cube 2300 to 23000 granularity to be not more than 0.2 μ m, therefore had the ability to filter out great majority our known source of infection at present at the cover body internal filter.
Preferred filters 7 is equipped with an O RunddichtringO near the upstream of air bleeding valve 2, the front of the prime cleaner 7A that filter 7 is made at a tissue/non-tissue (tissue-non-tissue).Filter 7 and prime cleaner 7A both can be removed and replace.
Among the current embodiment, outer cover 4 comprises 2 half shells 8 and 9, and it can be made and can be fastened along fillet separately by plastic material, so that close cage tool (Fig. 2).
Fillet place along whole first half shell 8 (lid of just mentioning 8) is provided with a closing seam circle, and its cross section is the narrow ancient piece of jade, round, flat and with a hole in its centre of U type.
The thickness of two the U types of O-ring seal that the are interpreted as limit ancient piece of jade, round, flat and with a hole in its centre of " narrow ancient piece of jade, round, flat and with a hole in its centre cross section " described herein can not surpass 1/3 of itself cross section horizontal maximum size; In currently preferred embodiment, closing seam circle 12 is to be made according to certain ratio by silica gel, and its ratio is (narrow ancient piece of jade, round, flat and with a hole in its centre thickness)/(U type cross-sectional maximum dimension) between 3.5-4 greatly.
There is the sealing ring of a narrow ancient piece of jade, round, flat and with a hole in its centre to make (as silica gel) by not having an elastomeric material of ductility, therefore can bear the pressure that typical high-pressure and high-temperature steam is disinfected, by the clossing pressure that is born by cage tool other parts, the sealing that narrow decline with thanks can guarantee prevents that air from leaking.
The U RunddichtringO is provided with 4 ribs 13 and 14 in this preferred embodiment, and they are triangular in shape and along sealing ring total length continuous distribution; Each rib 13 is arranged on the end of two branches of U type, and rib 14 is located at the bottom in U type cross section then.
Shape at the carriage of the ccontaining sealing ring 12 on two and half shells is can it be filled in (at its vertical direction) on four ribs 13,14 as Fig. 4 when closing the cage tool, has slight flexural deformation (Fig. 4 A) like this on both sides and has produced sealing effectiveness to such an extent as to be close to a fillet ancient piece of jade, round, flat and with a hole in its centre by a narrow ancient piece of jade, round, flat and with a hole in its centre.
Therefore compare other known sealing ring, this sealing ring can guarantee the whole obturation effect that prevents that air from leaking.
In order to guarantee a more effective sealing effectiveness and distribute clossing pressure along fillet more equably that the cage tool in this preferred embodiment is rectangular, is equipped with a restraint zone 15 (Fig. 1) in each both sides, long limit; This behave more helps large-sized cage tool.
Each restraint zone 15 comprises that a hook spare 16 (Fig. 5) and one are fixed on the connecting rod 17 that covers on 8 to hook spare 16, and restraint zone can be in the locking of cage tool closing position, and can release rebound between two settling positions.
Preferred but optional, 2 hook spares at 2 restraint zones of the same side of cage tool are attached to (Fig. 1 on (or being connected) Connection Element 18,5), make 2 members to hook simultaneously or to break off relations, can operate quickly like this and reduce to forget one possibility in a plurality of clasp of fastening.
In addition, each in 2 Connection Elements 18 can be locked in a fastening position or by a safety lock release.In the present embodiment, safety lock comprises that button 19 and cross section are the pin 20 (Fig. 1 and 5) of T type.T type pin 20 is one-body molded with lid 8, and button 19 is installed on the Connection Element 18 and can slides up and down by relative its; When two restraint zones 15 are hooked, safety switch 19 can be pressed, thus a groove on the button 19 be plugged into pin 20 above, to stop opening of 2 restraint zones 15, open the cage tool and at first want lifting button 19.So just can prevent from by mistake or by accident to open the cage tool, for example the cage tool drops or meets other object.
On the other hand, restraint zone 15 ' separates under another form of Figure 13 A and Figure 13 B.
Preferred restraint zone 15 is provided with a pair of rib 141, and (Figure 14 A, 14B), its energy and connecting rod 17 produce frictional force.The frictional force of 17 on restraint zone 15 and connecting rod make restraint zone 15 half shell 8 cover on half shell 9 or half shell 8 and 9 separation processes of half shell in can be held released state respectively.This separation can prevent undesirable interference.
Preferably make the minimizing noise buffer 21 (dotted portion among Fig. 1) of (for example rubber or elastomeric material) at the one or more flexible materials of the installed inside of each Connection Element 18, it can reduce, and Connection Element 18 collides the noises that cover 8 generations when closing the cage tool, to avoid frightening the animal in the cage tool.
Fig. 7 is a tangent plane schematic diagram of valve 2 and the passage that has shown air turnover cage tool.According to current embodiment (valve 1 among the current embodiment is to make with essentially identical method): valve 2 is connected with exhaust loop (following meeting is introduced in detail) with an air inlet, comprise a tubulose moving meter 200 of making by suitable rigid plastic material (being called slide block 200), hereinafter can be to this detailed introduction, with 2 sealing rings 201 and 202 (the O RunddichtringO that 2 rubber for example shown in Figure 7 or elastomeric material are made): O RunddichtringO 201 is positioned at the outside of outer cover 4, the air that can obviously reduce between slide block 200 and pedestal 203 leaks (when valve 2 is in open mode and places the right fully, this moment, it was connected with the air distribution loop, slide block just slides at pedestal, hereinafter can introduce in detail), otherwise, O RunddichtringO 202 is positioned at outer cover 4 inside, the air of avoiding or reducing at least significantly between slide block 200 and pedestal 203 leaks (shifted onto by the return spring that does not have to show when valve 2 and close and place fully the left side, disconnect with the air distribution loop this moment).Among Fig. 7, arrow indication air is by the path of valve.
No matter open or close in this way and can make valve 2 reach double containment to prevent to reveal effect.
When slide block 200 mediates, because valve opens or closes, air discharged can be avoided leaking because of negative pressure or superpressure (with respect to the environmental pressure in the cage tool) outside the cage tool between slide block 200 and seat 203.
(do not show) that in other embodiments the function of slide block 200 can be replaced by a moving meter, for example rotate or the pivot spinner member that the pair of O RunddichtringO can be replaced by a unitary elasticity element that can reach the double containment effect.
Fig. 8 is the schematic diagram of pressure/negative pressure display unit in, is label 300 among the figure, can be mounted this favourable device based on cage tool of the present utility model.
This display unit comprises an indicator film 301 of for example making with silica gel, it can be out of shape according to the different pressures of the cavity 302 that is positioned at overcoat 4 or move, and this is because of zone 303 pneumatic communications of cavity 302 with the cavity 302 of chamber 304 that is positioned at filter 7 downstreams and air bleeding valve 2 upstreams and outer cover 4 outsides.
Pointer 305 one are fixed on the indicator film 301, rely on the distortion (enter or break away from cylindrical base 306) of film.The head of pointer preferably scribbles color, and is therefore high-visible when it is projected into the outside.
By observing the top of pointer 305, an operator can perceive at once by a simple still reliable device, if the inside based on cage tool of the present utility model is operated in negative pressure or superpressure by expection, or an abnormal conditions appears, the consistent risk that causes existing source of infection to leak of internal pressure for example with environmental pressure, thus make a response fast.
The plate-like bracing frame 307 that has held all other parts of display unit is fixed on the outer wall of cover 4 by pair of O RunddichtringO 308 and 309, enough sealings have been guaranteed like this, prevent that inner air from leaking, do the effect that can reach " float and connect " like this, this effect can have certain compensation to be in the aggravation distortion that produces when autoclaving is handled when the cage tool.
For greater safety, pressure/negative pressure display unit 300 is placed in the downstream of filter 7 and the upstream of air bleeding valve 2, is positioned at a free of contamination zone in the downstream of HEPA 7.
Fig. 9 and 10 is cage tool and the ventilating systems about above-described ccontaining laboratory animal.
Cage system among the current embodiment comprises a cage, and it defines a lot of frameworks, and each can hold a cage tool 100 (or a plurality of cage tool 100).
Each cage tool 100 is set on the horizontal slide rail 22 of cage system by sliding support 121 (Fig. 1 and Figure 12).Amplify Figure 12 and can show better that sliding support 121 is furnished with lifting device 122 at two ends, its end is preferably inclination, when the cage tool is inserted in the cage system, guarantees that the lifting device 221 of itself and slide rail 22 respective end is corresponding, and the cage tool is locked on its position.
When being inserted into cage tool 100 in the cage system, sliding support 121 along slide rail 22 whole process to lower slider, when joint 603 elastic attachment arrive valve 1 and 2 (Fig. 3), the elasticity of joint 603 plays a role, so lifting device 122 guarantees that it is fully corresponding with lifting device 221.In order to remove cage tool 100 from cage system, need to push the cage tool to joint 603.
The front end of cage tool is raised, and therefore preceding lifting device 122 is elevated with respect to lifting device 221, and the cage tool is removed, and joint 603 breaks away from valves 1 and 2.
The shape of slide rail and support can make cage tool 100 be in stationary state by the elasticity of utilizing joint 603, and power operation that need not be extra.
Support frame is equally also supporting a series of pipeline 600-602 and 614 (Fig. 9), and the cage tool 100 that pipeline is responsible for from be inserted in cage system sucks and discharge air.
Air is by a trunk line 600 from tight suction of external rings, the secondary pipeline 601 of flowing through different afterwards, secondary pipeline 601 is connected with trunk line 600 Pneumatic parallels, by a pair of jointing 603 (Fig. 9 and 10): 603 first port is connected with the intake valve 1 of cage tool 100 and imports fresh air, 603 second port is connected with the air bleeding valve 2 of same cage tool and discharges off-air, air-flow is imported the cage tool 100 that is inserted in the cage by it.
The circular top 604 of joint 603 is connected to corresponding recessed surperficial 204 (Fig. 7) on the valve 1 and 2 of cage tool.
The termination 604 of two joints 603 and concave surface 204 preferably all have the spherical arc shape shape, but latter's radius greater than the former: by the mismatch error on compensation attaching parts surface, this connection shape can obtain better sealing effectiveness in order to avoid from coupled valve/mouth leakage air.
The applicant empirical tests top 604 by the joint 603 made of hard plastic material and dimple 204 than obtaining better sealing effectiveness with soft or resilient material, and cause the possibility of leakage can be by in pressure reduction (superpressure of above having mentioned or the negative pressure) elimination of inside and outside environment of circulating of ventilating by connection.
The waste gas of discharging from the cage tool arrives at main exhaust pipeline 602 and discharging by secondary discharge duct 614 (Fig. 9).
Second aspect of the present utility model, the distribution loop of turnover cage tool 100 be connected to one pneumatic first-born grow up to be a useful person 605 (for example an air pump or ventilation blowers) and if play a) that pneumatic first-born growing up to be a useful person 605 is in upstream position in air circulation, it is suction air from cage tool 100 only, or b) if pneumatic first-born growing up to be a useful person 605 is in downstream position in air circulation, it only injects air in cage tool 100, and, can be not simultaneously do not inject air and from the downstream suction air of cage tool from the upstream to the cage tool just as ventilation of knowing now and air distribution system.
This can bring following advantage: if some cage tools 100 utilizations pump into air and ventilate from the combined system that the downstream suction air carries out simultaneously from the upstream, when the aspiration pump in cage tool 100 downstreams breaks down, superpressure with respect to external environment condition in the cage will be inevitable, because upstream pump can constantly be injected air; Therefore the cage system of level of security BSL3 should be kept cage tool 100 and permanently is in negative pressure state, if the superpressure situation, just might cause outside source of infection is leaked to by the cage tool.
Substitute as opposite design, ventilating system of the present utility model pneumatic first-born grown up to be a useful person and 605 badly when breaking down caused its afunction, but cage tool 100 inside and outside pressure differentials can remain unchanged.The continuity of function can be realized that this pump is also only pressed separately or suck by a deposit pump.
When upstream pump breaks down and the pressure of cage tool 100 when being higher than environmental pressure, the first known ventilating system replacement work forms an even environment, can embody its advantage according to the ventilating system of second aspect of the utility model in this type of situation.
Pneumatic first-born 605 a pneumatic control cage, the different draught heads inside and outside the control cage can write down of being connected to of growing up to be a useful person.This draught head can make pneumatic first-born 605 the automatic regulatory function of growing up to be a useful person guarantee that keeping said numerical value at each cage tool is setting in the threshold parameter.The control cage can be equipped with the system of an energy Presentation Function and security parameter.
Pneumatic first-born 605 an anti-tampering feed unit of outfit and 2 engines of growing up to be a useful person.When wherein a generator quit work, the signal (plus or minus) of keeping the inside and outside different pressures of cage tool still was guaranteed.
Ventilating system preferably includes at least one upstream filter 607 (Fig. 9) and filtered before importing the cage tool from the air of external environment condition suction, also has at least one downstream filter 608, the downstream comprises that downstream 100 from the cage tool is to the outside, before the ventilating system discharging, downstream filter 608 is filtered the air of discharging from the cage tool, further reduces the risk of polluting; Upstream filter 607 and/or downstream filter 608 are preferably the highly effective particle air cleaner.
When a upstream highly effective particle air cleaner was provided with, joint 603 can not wanted seal approach, because the risk of leaking can be got rid of because of the existence of highly effective particle air cleaner.
Advantageously, when the cage tool 100 of a ventilating system is compared with the external world when being in negative pressure, at least one is only worked as valve to the air fed joint 603 of cage tool (type that provides as Figure 10), when it is connected with a cage tool 100, just open, yet when it separates with any one cage tool, just close: the situation about taking place of not wishing so as shown in figure 11 just can be avoided: in the ventilating system in Figure 11, delivery port does not have valve 603, if (as shown) a cage tool 100 is not inserted in the cage, the air that is not filtered from import directly sucks from environment, is positioned at upstream filter 607 filtered airs that whole system is bled and located with after stain.
603 port in Figure 10, closing of valve is that elastic force by bellows 605 (when the cage tool lacks air it is supplied with) is finished, elastic force upwards promotes shutter 604 and makes nose cone 606 valve-offs.When valve 1 and valve 2 promotion Spherical Bottom 604, the latter opens and makes air pass through hole 609.
Have in a preferred embodiment air distribution duct inclination support frame by roller removable, the ventilation blower that can supply gas or bleed is installed in cage, so it can roll in the plane and freely move to another from a place and keep a plurality of cage tools 100 and always is connected to air pressure or negative pressure generator loop.
It should be noted how to make ventilating system that the front introduced and the cage tool of ccontaining animal merge advantage, these advantages (the particularly convenience of Shi Yonging and fast) comprise the separate ventilation cage tool system that typically has sealing source of infection or harmful source, aspect basic security, be characterised in that its isolation structure is identical with known isolator.
The applicant has done detection, above-mentioned cage tool and ventilating system can guarantee to reach BSL3 or equal effect go to be controlled at the cage tool inside and outside between and isolated or existed source of infection and harmful source in the ventilating system.
Described cage tool and ventilating system can be opened change and the adjustment that gives to a certain degree, but can not exceed scope of the present utility model.
For example, described ventilating system also can be used with known laboratory animal cage tool or with using with the different cage tool of first characteristics of the present utility model.
The modifications and variations that any claim scope is equal to all are regarded as being included in the category of the utility model protection.
Claims (34)
1. the cage tool that is suitable for ccontaining laboratory animal thing comprises:
At least one can make air enter intake valve in the cage tool;
At least one can make air be discharged into the air bleeding valve the external environment condition from cage tool inside;
One sealed in order to avoid the outer cover that air leaks, can be with environment in the outer cover and the outer environment separation of cover body, environment is positioned at the downstream of at least one intake valve and the upstream of at least one air bleeding valve in the outer cover, and outer cover also/maybe can hold the environment of any source of infection in the upstream of the described downstream that is arranged at least one intake valve and at least one air bleeding valve.
2. cage tool according to claim 1, comprise a filter that is arranged in the described outer cover, before air was discharged from outer cover by at least one air outlet valve, it can filter the air in zone that can ccontaining laboratory animal from described outer cover, and described filter is set at the upstream of air bleeding valve.
3. cage tool according to claim 2, wherein said filter can suppress and contain great majority and swim in airborne potential source of infection in the cover.
4. according to claim 2 or 3 described cage tools, be equipped with a tissue/non-prime cleaner of organizing before the wherein said filter.
5. cage tool according to claim 4, wherein said filter and described prime cleaner are detachable and interchangeable.
6. according to claim 2 or 3 described cage tools, wherein said filter is a highly effective particle air cleaner, or other meet 4 grades or 5 grades of filters of ISO146441.1 standard, or a M2.5 or a M3.5 level highly effective particle air cleaner that meets Federal Specification 209E.
7. cage tool according to claim 1, comprising at least 2 half shell, a upper half shell, a lower half shell, they fasten along its fillet, so that closed described outer cover under sealing, at least one closing seam circle is along the fillet setting of at least one half shell in addition, and wherein said closing seam circle has the cross section of band thin-walled.
8. cage tool according to claim 7, wherein said intake and exhaust valve all is positioned at described upper half shell.
9. cage tool according to claim 7, wherein said at least one closing seam ring cross-section is the U type.
10. cage tool according to claim 9, wherein said at least one closing seam circle comprises at least one along the rib that the sealing ring longitudinal extension goes out, and makes it be against the fillet of one and half shells.
11. cage tool according to claim 7, wherein the circumference of half shell fillet limits one or more, the cage tool comprise one can by push one of them half shell to second half shell to realize closed system, also being included in has two restraint zones at least one described, make two and half shells reversibly to link closely each other.
12. cage tool according to claim 11, wherein the face of at least one fillet circumference of at least one half shell comprises a Connection Element, and it connects at least two described restraint zones, so that realize itself and being connected or disconnecting connection of another half shell simultaneously.
13. cage tool according to claim 11, wherein each described restraint zone comprises a hook spare and a connecting rod, and the fixing described hook spare of connecting rod is to described upper half shell, and linking closely band can be locked in closing position, and in the release of rebounding of two settling positions.
14. cage tool according to claim 13, wherein said hook spare are provided with the rib that can cause producing with described connecting rod frictional force, described frictional force make member upper half shell cover on lower half shell or upper half shell and lower half shell separation process in can keep released state.
15. cage tool according to claim 12, wherein said Connection Element can be locked in closing position or pass through a safety lock release.
16. cage tool according to claim 11, wherein said two restraint zones separate.
17. cage tool according to claim 12 comprises that at least one can lock or the lock/unlock device of at least one Connection Element of release.
18. cage tool according to claim 1 comprises being used to indicate internal mask pressure whether to be higher or lower than the internal negative pressure of ambient pressure/superpressure indicator.
19. cage tool according to claim 18, wherein internal negative pressure/superpressure indicator comprises:
An indication film, its at least a portion can be higher than, be equal to or less than the external pressure distortion or move according to the pressure in the described outer cover;
Cover outer visible can display position and the indicator that changes of indication film.
20. cage tool according to claim 1 comprises between at least one intake valve and at least one air bleeding valve at least:
The moving meter that can between valve opening and closed position, move, under the state of opening, air can flow in covering outside the cover by valve, and vice versa; Separate with external environment condition in valve will cover when the closed position, sealing prevents that air from leaking;
The pedestal of a moving meter, moving meter can be therein from the enable possition to the closed position;
When being in the opening and closing state, valve can preventing or be limited in the double seal that air leaks between moving meter and its pedestal.
21. cage tool according to claim 20, wherein double seal comprises at least: a double density seal and two sealing rings, and at least one main body is to be made by rubber or flexible member.
22. the ventilation decorum of the cage tool of the described ccontaining laboratory animal of arbitrary as described above claim comprises:
A plurality of cages, each can hold at least one cage tool, and its cage tool can be settled one or more laboratory animal in order;
An air distribution loop can suck air from the external world, being transported to each is inserted in the cage tool in the cage, and from described cage tool discharge, also comprise pneumatic first-born growing up to be a useful person, it can swim over to the downstream suck air from described distribution loop separately, or individually by swimming over to the downstream drain air on the described distribution loop.
23. ventilating system according to claim 22, described air distribution loop comprises a pipeline, it can deliver air to the cage tool of at least two ccontaining laboratory animals, Pneumatic parallel each other, described pipeline is provided with plurality of interfaces, each joint all can be opened when the cage tool inserts cage and valve be arranged and make air through supplying to the cage tool, and can also can not close and block air flue when having the cage tool to insert cage and valve is arranged.
24. ventilating system according to claim 23, wherein said a plurality of interface is provided with a button-head, matches with the concave form surface of described valve in this termination.
25. ventilating system according to claim 24, described button-head and described concave form surface all are spherical calottes, and latter's spherical radius is bigger than the former.
26. ventilating system according to claim 24, described button-head and described concave form surface are all made by hard plastic material.
27. ventilating system according to claim 22, wherein said cage tool comprises the horizontal slip support, described cage comprises horizontal slide rail, described cage tool places on the described slide rail by described sliding support, described sliding support is provided with lifting device in its end, when the cage tool is inserted into cage, guarantee that the lifting device at itself and described slide rail two ends is corresponding, the cage tool is fixed.
28. ventilating system according to claim 27, wherein said joint is flexible, helps that the cage tool is inserted described cage neutralization and therefrom takes out.
29. ventilating system according to claim 22, also comprise at least one upstream filter, it filtered from the external environment condition inhaled air before importing the cage tool, with at least one downstream filter, the air that its filtration before discharging outside ventilating system is discharged from the cage tool, it is positioned at cage tool downstream and outside the cage tool.
30. ventilating system according to claim 29, wherein said upstream filter and/or described downstream filter all are the highly effective particle air cleaners.
31. ventilating system according to claim 23, wherein said pneumatic first-born growing up to be a useful person and control cage pneumatic a connection of tool, the controlled cage tool record of cage tool external and internal pressure difference, described control cage tool is provided with a system can show working condition and security parameter.
32. ventilating system according to claim 23, wherein said pneumatic first-born growing up to be a useful person is provided with uninterrupted power source and two electromotor, as in two electromotor one when breaking down, still can safeguard the signal of cage tool external and internal pressure difference, on the occasion of or negative value, still can be guaranteed.
33. ventilating system according to claim 23, wherein closing by a flexible member of at least one described interface controlled.
34. ventilating system according to claim 22 comprises that at least one according to claim 1 and the cage tool that is connected with described air distribution loop.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI20040530 ITMI20040530A1 (en) | 2004-03-19 | 2004-03-19 | CAGE SUITABLE FOR ACCOMMODATION OF LABORATORY ANIMALS AND RELATED VENTILATION SYSTEM |
| ITMI2004A000530 | 2004-03-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2927678Y true CN2927678Y (en) | 2007-08-01 |
Family
ID=34966221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNU2005900000260U Expired - Lifetime CN2927678Y (en) | 2004-03-19 | 2005-03-18 | Cage suitable for housing laboratory animals in isolation and related ventilation system |
Country Status (4)
| Country | Link |
|---|---|
| CN (1) | CN2927678Y (en) |
| DE (1) | DE212005000018U1 (en) |
| IT (1) | ITMI20040530A1 (en) |
| WO (1) | WO2005089536A1 (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103355182A (en) * | 2012-03-26 | 2013-10-23 | 凌云博际（北京）科技有限公司 | Individual ventilated cage and air faucet used for ventilated cage |
| TWI495428B (en) * | 2013-10-30 | 2015-08-11 | ||
| CN105706943A (en) * | 2014-12-18 | 2016-06-29 | 株式会社东方 | Laboratory animal breeding apparatus |
| CN106550898A (en) * | 2015-09-28 | 2017-04-05 | 魏佑震 | Intensive collection cage Animal House |
| CN109247239A (en) * | 2017-07-13 | 2019-01-22 | 泰尼百斯股份公司 | The lid of cage for experimental animal and the cage for experimental animal including the lid |
| CN110130757A (en) * | 2019-05-21 | 2019-08-16 | 苏州市冯氏实验动物设备有限公司 | A kind of the parallel-moving type cage box buckle structure and cage box of bio-safety IVC equipment |
| CN113331064A (en) * | 2021-04-23 | 2021-09-03 | 温州医科大学 | Special transport case of SPF animal |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG132539A1 (en) * | 2005-11-24 | 2007-06-28 | Linair Bio Science Pte Ltd | Individual ventilated caging system |
| KR100932112B1 (en) * | 2008-12-12 | 2009-12-16 | (주) 쓰리샤인 | The water supplying valve for the lab animal isolation cage |
| KR100932114B1 (en) * | 2008-12-31 | 2009-12-16 | (주) 쓰리샤인 | The air supplying valve for the lab animal isolation cage |
| DE202011101537U1 (en) | 2011-06-07 | 2011-11-10 | Rung Shin Plastic Industrial Co., Ltd. | Breeding cage for experimental animals |
| US8851016B2 (en) | 2011-06-08 | 2014-10-07 | Rung Shin Plastic Industrial Co., Ltd. | Breeding cage for experimental animal |
| WO2014181911A1 (en) * | 2013-05-09 | 2014-11-13 | 주식회사 우레아텍 | System for breeding laboratory animal and air supply/discharge valve structure for cage for breeding animal |
| KR101471406B1 (en) * | 2013-05-09 | 2014-12-11 | 주식회사 우레아텍 | System of animal breeding for experiment |
| KR101754406B1 (en) * | 2014-11-10 | 2017-07-06 | 주식회사 우레아텍 | System of animal breeding for experiment |
| AU2015394219B2 (en) | 2015-05-11 | 2017-12-07 | Bigcity Design Pty Ltd | Modular animal accommodation |
| CN105498866B (en) * | 2016-01-12 | 2017-10-24 | 四川川净洁净技术股份有限公司 | CCN biocontainment laboratories |
| AT518394B1 (en) * | 2016-10-20 | 2017-10-15 | Bscheiden Manfred | Wubler CATCHER |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1273478B (en) * | 1995-01-31 | 1997-07-08 | Gazzada Tecniplast Srl | CONTAINER FOR ENCLOSURE |
| US5865144A (en) * | 1997-08-29 | 1999-02-02 | Semenuk; Michael | Ventilated cage for laboratory animal |
| US6257171B1 (en) * | 1998-01-16 | 2001-07-10 | Animal Care Systems, Inc. | Animal caging and biological storage systems |
| US6308660B1 (en) * | 1999-06-17 | 2001-10-30 | Allentown Caging Equipment Co., Inc. | Bio-containment animal cage system |
| DE10035806A1 (en) * | 2000-07-22 | 2002-02-07 | Deutsches Krebsforsch | Cage shelving system with forced ventilation |
| KR100479022B1 (en) * | 2002-05-22 | 2005-03-30 | 주식회사 오리엔트 | Perfect airtight-type cage system for protecting transition of pathogen |
-
2004
- 2004-03-19 IT ITMI20040530 patent/ITMI20040530A1/en unknown
-
2005
- 2005-03-18 WO PCT/IB2005/000701 patent/WO2005089536A1/en active Application Filing
- 2005-03-18 DE DE212005000018U patent/DE212005000018U1/en not_active Expired - Lifetime
- 2005-03-18 CN CNU2005900000260U patent/CN2927678Y/en not_active Expired - Lifetime
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103355182A (en) * | 2012-03-26 | 2013-10-23 | 凌云博际（北京）科技有限公司 | Individual ventilated cage and air faucet used for ventilated cage |
| TWI495428B (en) * | 2013-10-30 | 2015-08-11 | ||
| CN105706943A (en) * | 2014-12-18 | 2016-06-29 | 株式会社东方 | Laboratory animal breeding apparatus |
| CN106550898A (en) * | 2015-09-28 | 2017-04-05 | 魏佑震 | Intensive collection cage Animal House |
| CN106550898B (en) * | 2015-09-28 | 2021-05-14 | 魏佑震 | Intensive cage-collecting type animal house |
| CN109247239A (en) * | 2017-07-13 | 2019-01-22 | 泰尼百斯股份公司 | The lid of cage for experimental animal and the cage for experimental animal including the lid |
| CN110130757A (en) * | 2019-05-21 | 2019-08-16 | 苏州市冯氏实验动物设备有限公司 | A kind of the parallel-moving type cage box buckle structure and cage box of bio-safety IVC equipment |
| CN113331064A (en) * | 2021-04-23 | 2021-09-03 | 温州医科大学 | Special transport case of SPF animal |
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI20040530A1 (en) | 2004-06-19 |
| WO2005089536A1 (en) | 2005-09-29 |
| DE212005000018U1 (en) | 2006-11-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CX01 | Expiry of patent term |
Expiration termination date: 20150318 Granted publication date: 20070801 |