CN2852102Y - Apparatus for testing mechanical property of high-sensitivity small-tension membrane-like biomaterial - Google Patents

Apparatus for testing mechanical property of high-sensitivity small-tension membrane-like biomaterial Download PDF

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Publication number
CN2852102Y
CN2852102Y CNU2005200106638U CN200520010663U CN2852102Y CN 2852102 Y CN2852102 Y CN 2852102Y CN U2005200106638 U CNU2005200106638 U CN U2005200106638U CN 200520010663 U CN200520010663 U CN 200520010663U CN 2852102 Y CN2852102 Y CN 2852102Y
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China
Prior art keywords
load
ring groove
pressure regulating
bearing
plate
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Expired - Lifetime
Application number
CNU2005200106638U
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Chinese (zh)
Inventor
伍津津
赵建华
周凌
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Third Military Medical University TMMU
Third Affiliated Hospital of TMMU
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Third Affiliated Hospital of TMMU
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Priority to CNU2005200106638U priority Critical patent/CN2852102Y/en
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Publication of CN2852102Y publication Critical patent/CN2852102Y/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Abstract

The utility model relates to an apparatus for testing mechanical properties of a high-sensitivity small-tension membrane-like biomaterial, which is formed by assembly of a pressure transmitter 1, a pressure tank 2, a specimen fixing ring 4, a loading lofting floor 5, a sealing washer 6, a top panel 7a, a load bearing panel 7b, a movable clamp plate 8, a tight contact screw rod 10, a bearing 11, a dumbbell-shaped screw 12, a pressure regulating tank 13, a pulley wheel 14, a glass pipe 15, a lifting pull rope 16, a soft tube 17, a stepper motor 18, a data lead 19, a control lead 20 and a microcomputer 21. The structure is simple and reasonable, and the utility model can conduct convenient and accurate testing for products, such as tissue engineered skin, bones, blood vessels, muscle tendons, muscles, etc., soft tissue materials, etc. The testing values are all calculated by Pa, and the operation and control are quick and convenient. The continuous variation of the loading can be sensitively reflected, the environmental interference can be resisted and the accuracy of the testing data can be ensured. The utility model provides an ideal testing tool for mechanical properties for the bulk production and quality control of the tissue engineered biomaterials.

Description

Apparatus for testing mechanical property of high-sensitivity small-tension membrane-like biomaterial
One, technical field
The utility model belongs to the strength characteristics of what with mechanical stress test solid material, particularly a kind of solid material apparatus for testing mechanical that applies stable tension or pressure.
Two, background technology
Along with the progress and the maturation of tissue engineering technique, the development of organization engineering skin is also maked rapid progress with application.Clinical for guaranteeing that organization engineering skin is applied to better, its biophysical properties, particularly biomechanical property should obtain paying much attention to.In order to quantize the biomechanical property of the membranaceous biomaterials of small tension receiving coil such as organization engineering skin, must develop a kind of device that can detect its mechanical property.
Be used for detecting the instrument of the mechanical property of soft tissue or bone at present, what can detect all is the biomechanical property of high-tension biomaterial (animal or human's isolated skin and soft tissue thereof, corpse), and detected value all calculates with MPa, belongs to the biomaterial testing machine in fact.Yet the biological organic material of many low-tensions, Yan Jiu tissue engineering product as organization engineering skin product, organizational project bone product, can not detect with this biomaterial testing machine especially in the last thirty years.
On April 22nd, 1992, Granted publication had a name to be called " biomaterial mechanical property testing device " Chinese utility model patent ZL91222000.7, it is mainly by body, crossbeam, plumbing arm, power and kinematic train thereof, formations such as tension force sensing and displacement digital display system and corresponding fixture.Plumbing arm and transmission rod can fall in the liquid, and sample is tried in given solution.Power and kinematic train thereof are moved crossbeam up and down, make the sample generation length and the tension variation that are clamped between two fixtures.The latter transfers electric signal input register system to by displacement digital display and power sensor-based system respectively, finishes the detection to the biomaterial mechanical characteristic.This device can be measured the mechanical property of some biomaterial really, and cost is low.But the hook-type fixture of this device and folder formula fixture can only fixedly be in ring-type and strip biomaterial in the nutrient solution, are not suitable for the fixing biomaterials such as organization engineering skin that break away from nutrient solution; Secondly, this matching requirements biomaterial is loaded in the interior solution of casing, and aptitude test when needing electromagnetism to be heated to water temperature satisfaction can not make test break away from nutrient solution; This device is to move up and down that physical property is elongated and shorten sample and measure tensile strength by leading screw, uses inconveniently, quantizes also not accurate enough.
Three, summary of the invention
Above-mentioned defective at prior art " biomaterial mechanical property testing device " existence, we are according to the fluid pressure principle, adopt indirect pressure application to load, propose meter and make the high-sensitivity small-tension film-shaped biomaterial mechanic device for detecting performance that a kind of structure is different from prior art fully, make sample when detecting, can break away from nutrient solution, and do not need directly to elongate or shorten sample, can accurately detect product and other mechanical properties such as engineered skin, bone, blood vessel, tendon, muscle easily as mesenterium, manadesma, cardiac valves soft-tissue material etc.
Technical solution adopted in the utility model is as follows.
A kind of high-sensitivity small-tension film-shaped biomaterial mechanic device for detecting performance includes frame, pressure unit, microcomputer, data conductor and pilot, it is characterized in that:
1) it also has forbay, sample set collar, load sample platform, packing washer, top panel, load-bearing panel, active clamped plate, fastening screw, bearing, dumbbell shape nut, pressure regulating box, pulley, glass tube, lifting stay cord, flexible pipe and stepper motor;
2) the suitable for reading and pressure unit of forbay is tightly connected, the center pit contraposition coupling of end opening and top panel, and be connected with the plate face seal at the bottom of the case, the bottom surface of plate has ring groove in the above, plate is arranged with the load sample platform that top is circular platform type in the above, load sample platform center has cylindrical hole, round platform stretches in the center pit of top panel, sample set collar and round platform coupling are nested, position, the corresponding load sample platform of plate ring groove deep bid upper surface has ring groove in the above, in ring groove, be placed with packing washer, have ring groove in load sample platform deep bid lower surface;
3) be arranged with the active clamped plate that is nested with framework pillar at the load sample platform, active clamped plate has conical central hole, and the upper surface is provided with the convex annular that is complementary with load sample platform deep bid lower surface ring groove;
4) the dumbbell shape nut passes the center pit of load-bearing panel and closes with the weight-bearing surface integrated circuit board, the dumbbell shape nut can be rotated, be provided with bearing between the lower nut head of dumbbell shape nut and the load-bearing panel, be welded with handle on the top nut head of dumbbell shape nut, fastening screw and the screwed connection of dumbbell shape nut, fastening screw top are a pot mouthful top shape and prop up active clamped plate;
5) pressure regulating box is arranged on the load-bearing panel, the pressure regulating box top is communicated with forbay, use soft pipe connection between pressure regulating box bottom and the glass tube, pulley is arranged on the above height and position in pressure regulating box top, lifting stay cord pile warp pulley one end links to each other with the glass tube tube head, other end solderless wrapped connection is connected with pilot between stepper motor and the microcomputer on the wheel disc of stepper motor, be connected with data conductor between pressure unit and the microcomputer.
High-sensitivity small-tension film-shaped biomaterial mechanic device for detecting performance of the present utility model, before use, earlier glass tube is risen to the suitable height of high what pressure regulating box bottom by the lifting stay cord, in pressure regulating box, inject the clean water of certain liquid then, again film software sample to be detected is placed on the round platform mouth of load sample platform, putting the sample set collar collapses flat, rotate the dumbbell shape nut with spanner at last and promote fastening screw, the load sample platform is clamped between active clamped plate and top panel, make forbay-pressure regulating box total system be in sealing state.During detection, its principle of work is: microcomputer is after pilot sends steering order to stepper motor, driving the lifting stay cord by stepper motor slowly promotes glass tube, thereby make forbay pressure increasing and slowly increase with the pressure regulating box liquid level, realization evenly loads continuously to film sample to be detected, the breakdown pressure measurement data of the film sample that pressure unit is gathered is returned to be fed to by data conductor and is carried out data processing in the microcomputer, and in time obtains showing and storage.
High-sensitivity small-tension film-shaped biomaterial mechanic device for detecting performance of the present utility model, simple and reasonable, the sample clamping is simple and convenient, can be to the tissue engineering skin of low-tension, bone, blood vessel, tendon, product such as muscle and other are as mesenterium, manadesma, cardiac valves soft-tissue material etc. carries out convenience, detect accurately, detected value all calculates with Pa, operation control is quick convenient, sample can break away from nutrient solution when detecting, and do not need directly to elongate or shorten sample, it can reflect the continuous variation of load and the interference that can resist environment delicately, guarantees to detect the accurate of data.The utility model device provides a kind of desirable mechanical property testing tool for the batch process and the quality control of engineered biomaterial.
Four, description of drawings
Accompanying drawing is the broken section structural representation of the utility model high-sensitivity small-tension film-shaped biomaterial mechanic device for detecting performance.
In the drawings, 1-pressure unit, 2-forbay, 3-sample, 4-sample set collar, 5-load sample platform, 6-packing washer, 7-frame, the 7a-top panel, 7b-load-bearing panel, 8-active clamped plate, 9-handle, the 10-fastening screw, 11-bearing, 12-dumbbell shape nut, 13-pressure regulating box, the 14-pulley, 15-glass tube, 16-lifting stay cord, 17-flexible pipe, the 18-stepper motor, 19-data conductor, 20-pilot, 21-microcomputer.
Five, embodiment
Further specify concrete structure and its principle of work when detecting of the utility model device below in conjunction with accompanying drawing.
A kind of high-sensitivity small-tension film-shaped biomaterial mechanic device for detecting performance includes frame 7, pressure unit 1, microcomputer 21, data conductor 19 and pilot 20, it is characterized in that:
1) it also has forbay 2, sample set collar 4, load sample platform 5, packing washer 6, top panel 7a, load-bearing panel 7b, active clamped plate 8, fastening screw 10, bearing 11, dumbbell shape nut 12, pressure regulating box 13, pulley 14, glass tube 15, lifting stay cord 16, flexible pipe 17 and stepper motor 18;
2) the suitable for reading and pressure unit 1 of forbay 2 is tightly connected, the center pit contraposition coupling of end opening and top panel 7a, and be connected with the plate face seal at the bottom of the case, the bottom surface of plate 7a has ring groove in the above, plate 7a is arranged with the load sample platform 5 that top is circular platform type in the above, load sample platform 5 centers have cylindrical hole, round platform stretches in the center pit of top panel 7a, sample set collar 4 is nested with the round platform coupling, position, plate 7a ring groove corresponding load sample platform 5 deep bid upper surface has ring groove in the above, in ring groove, be placed with packing washer 6, have ring groove in load sample platform 5 deep bid lower surfaces;
3) be arranged with the active clamped plate 8 that is nested with framework pillar at load sample platform 5, active clamped plate 8 has conical central hole, and the upper surface is provided with the convex annular that is complementary with load sample platform 5 deep bid lower surface ring grooves;
4) dumbbell shape nut 12 passes the center pit of load-bearing panel 7b and engages with load-bearing panel 7b, dumbbell shape nut 12 can be rotated, be provided with bearing 11 between the lower nut head of dumbbell shape nut 12 and the load-bearing panel 7b, the top nut head of dumbbell shape nut 12 is welded with handle 9, fastening screw 10 and 12 screwed connections of dumbbell shape nut, fastening screw 10 tops are a pot mouthful top shape and prop up active clamped plate 8;
5) pressure regulating box 13 is arranged on the load-bearing panel 7b, pressure regulating box 13 tops are communicated with forbay 2, be communicated with flexible pipe 17 between pressure regulating box 13 bottoms and the glass tube 15, pulley 14 is arranged on the above height and position in pressure regulating box 13 tops, lifting stay cord 16 pile warp pulleys 14 1 ends link to each other with glass tube 15 tube heads, other end solderless wrapped connection is connected with pilot 20 between stepper motor 18 and the microcomputer 21 on the wheel disc of stepper motor 18, be connected with data conductor 19 between pressure unit 1 and the microcomputer 21.
Its principle of work when detecting is: after injecting the clean water of certain liquid and device total system in advance tightened up sealing in pressure regulating box, microcomputer 21 sends steering order through 20 pairs of stepper motors 18 of pilot, driving lifting stay cord 16 by stepper motor 18 slowly promotes glass tube 15, thereby make forbay 2 pressure increasing and slowly increase with pressure regulating box 13 liquid levels, realization is to the even loading of film sample to be detected, the breakdown pressure measurement data of film sample that pressure unit 1 is gathered, return to be fed to by data conductor 19 and carry out data processing in the microcomputer 21, and in time obtain showing and storage.

Claims (1)

1, a kind of high-sensitivity small-tension film-shaped biomaterial mechanic device for detecting performance includes frame (7), pressure unit (1), microcomputer (21), data conductor (19) and pilot (20), it is characterized in that:
1) it also has forbay (2), sample set collar (4), load sample platform (5), packing washer (6), top panel (7a), load-bearing panel (7b), active clamped plate (8), fastening screw (10), bearing (11), dumbbell shape nut (12), pressure regulating box (13), pulley (14), glass tube (15), lifting stay cord (16), flexible pipe (17) and stepper motor (18);
2) the suitable for reading and pressure unit (1) of forbay (2) is tightly connected, the center pit contraposition coupling of end opening and top panel (7a), and be connected with the plate face seal at the bottom of the case, the bottom surface of plate (7a) has ring groove in the above, plate (7a) is arranged with the load sample platform (5) that top is circular platform type in the above, load sample platform (5) center has cylindrical hole, round platform stretches in the center pit of top panel (7a), sample set collar (4) is nested with the round platform coupling, position, plate (7a) the corresponding load sample platform of ring groove (5) deep bid upper surface has ring groove in the above, in ring groove, be placed with packing washer (6), have ring groove in load sample platform (5) deep bid lower surface;
3) be arranged with the active clamped plate (8) that is nested with framework pillar at load sample platform (5), active clamped plate (8) has conical central hole, and the upper surface is provided with the convex annular that is complementary with load sample platform (5) deep bid lower surface ring groove;
4) dumbbell shape nut (12) passes the center pit of load-bearing panel (7b) and engages with load-bearing panel (7b), dumbbell shape nut (12) can be rotated, be provided with bearing (11) between the lower nut head of dumbbell shape nut (12) and the load-bearing panel (7b), the top nut head of dumbbell shape nut (12) is welded with handle (9), fastening screw (10) and dumbbell shape nut (12) screwed connection, fastening screw (10) top are a pot mouthful top shape and prop up active clamped plate (8);
5) pressure regulating box (13) is arranged on the load-bearing panel (7b), pressure regulating box (13) top is communicated with forbay (2), be communicated with flexible pipe (17) bottom the pressure regulating box (13) with between the glass tube (15), pulley (14) is arranged on the above height and position in pressure regulating box (13) top, lifting stay cord (16) pile warp pulley (14) one ends link to each other with glass tube (15) tube head, other end solderless wrapped connection is on the wheel disc of stepper motor (18), be connected with pilot (20) between stepper motor (18) and the microcomputer (21), be connected with data conductor (19) between pressure unit (1) and the microcomputer (21).
CNU2005200106638U 2005-12-29 2005-12-29 Apparatus for testing mechanical property of high-sensitivity small-tension membrane-like biomaterial Expired - Lifetime CN2852102Y (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100429499C (en) * 2005-12-29 2008-10-29 中国人民解放军第三军医大学第三附属医院 Apparatus for testing mechanical property of high-sensitivity small-tension membrane-like biomaterial
CN102680267A (en) * 2012-05-24 2012-09-19 东南大学 Testing equipment for mechanical property of intravascular stents
CN111067668A (en) * 2019-12-27 2020-04-28 先健科技(深圳)有限公司 Force measuring device
WO2020183682A1 (en) * 2019-03-13 2020-09-17 国立大学法人東海国立大学機構 Mechanical property measurement apparatus for thin-film material

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100429499C (en) * 2005-12-29 2008-10-29 中国人民解放军第三军医大学第三附属医院 Apparatus for testing mechanical property of high-sensitivity small-tension membrane-like biomaterial
CN102680267A (en) * 2012-05-24 2012-09-19 东南大学 Testing equipment for mechanical property of intravascular stents
CN102680267B (en) * 2012-05-24 2014-09-10 东南大学 Testing equipment for mechanical property of intravascular stents
WO2020183682A1 (en) * 2019-03-13 2020-09-17 国立大学法人東海国立大学機構 Mechanical property measurement apparatus for thin-film material
JP7384451B2 (en) 2019-03-13 2023-11-21 国立大学法人九州大学 Mechanical property measuring device for thin film materials
CN111067668A (en) * 2019-12-27 2020-04-28 先健科技(深圳)有限公司 Force measuring device

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C14 Grant of patent or utility model
GR01 Patent grant
AV01 Patent right actively abandoned

Effective date of abandoning: 20081029

AV01 Patent right actively abandoned

Effective date of abandoning: 20081029

C25 Abandonment of patent right or utility model to avoid double patenting