CN2761140Y

CN2761140Y - Potentiometric recording electrode capable of local administration and one-way action

Info

Publication number: CN2761140Y
Application number: CN 200520094971
Authority: CN
Inventors: 曾秋棠; 刘福元; 毛奕
Original assignee: Union Hospital Tongji Medical College Huazhong University of Science and Technology
Current assignee: Tongji Medical College of Huazhong University of Science and Technology; Union Hospital Tongji Medical College Huazhong University of Science and Technology
Priority date: 2005-01-20
Filing date: 2005-01-20
Publication date: 2006-03-01
Anticipated expiration: 2015-01-20

Abstract

The utility model relates to an electric potential recording electrode capable of local administration and one-way action, which comprises an outer tube (1) and an inner tube (2), wherein a hollow cavity (8) is arranged between the outer tube (1) and the inner tube (2). Three pairs of electrode conducting wires (3, 4, 5) are respectively and symmetrically distributed in the hollow cavity (8) between the outer tube (1) and the inner tube (2) and in the hollow cavity (11) of the inner tube (2). Barbs (13) are arranged on the electrode conducting wires (3, 4, 5) which are positioned outside the outer tube (1), and a filling medium (6) is arranged in the inner tube (2). The utility model has the following advantages that a research on the electrophysiological characteristic of an animal to stride a ventricular wall in a body and out of the body can be satisfied; the depolarization order and the complex pole characteristic of striding the ventricular wall can be correctly reflected; all the electrodes are placed in the disposable mode; no electrodes fall off; no hemorrhagic complication occurs.

Description

But topical monophasic action potential recording electrode

Technical field

This utility model relates to and a kind ofly is used in the electrogram electrode that body and stripped large animal are striden the ventricle wall Research on electrophysiologicalcharacteristics, but more particularly it is a kind of topical monophasic action potential recording electrode.

Background technology

Ventricular muscles can be divided into electrophysiological characteristics different interior, in, outer three layers of myocardial cell, three layers of myocardium monophasic action potential of synchronous recording help the research of ventricular muscles electrophysiological characteristics and arrhythmia relation.Classic methods often adopts endocardium contact electrode or visceral pericardium adsorption electrode; Also have to adopt and divide the report of putting into three electrodes or three layers of myocardium monophasic action potential of combination electrode synchronous recording for three times.These methods have the following disadvantages: 1. all be the external force generation current of injury record monophasic action potential by physics, because heart is in the beating of not stopping the monophasic action potential jitter of traditional method record; 2. time of continuing of monophasic action potential record of short duration (approximate number minute to half an hour); 3. electrode is placed complexity, and localized accuracy and fixed fastness are uncertain; 4. the current potential of middle level cardiac muscle is local one pole electrograph, fails to record local bipolar electrograms; 5. do not possess the topical function.

Summary of the invention

The purpose of this utility model is to overcome the weak point of above-mentioned background technology, but and provides a kind of topical monophasic action potential recording electrode.It is the monophasic action potential of three layers of cardiac muscle of synchronous recording long-term and stably; The topical function can be used for studying the effect of local factor in ventricular arrhythmia in addition.

The purpose of this utility model reaches by following measure: but topical monophasic action potential recording electrode, and it comprises outer tube 1, interior pipe 2, between described outer tube 1 and the interior pipe 2 cavity 8 is arranged; There are three counter electrode leads 3,4,5 to be distributed in the cavity 8 between outer tube 1 and the interior pipe 2 respectively symmetrically and in the cavity 11 of interior pipe 2, three are positioned at cavity 8 electrode cables and pass outer tube 1 tube wall; In addition three electrode cables that are positioned at cavity 11 pass manage 2 and outer tube 1 on corresponding opening 12, the electrode tail end 7 of sealing, the sheath tube head end 10 of sealing are arranged at the two ends of described outer tube 1 and interior pipe 2, on the described outer tube 1 tee T 9 is arranged, described tee T 9 communicates with cavity 8, on the described electrode cable 3,4,5 that is positioned at outside the outer tube 1 barb 13 is arranged, in the pipe 2 filled media 6 is arranged in described, described filled media 6 is an agarose potassium chloride gel.

In technique scheme, described distance between the electrode cable that homonymy is adjacent on the outer tube 1 equates.

In technique scheme, described electrode cable 3,4,5 for being coated with the filamentary silver of insullac outward, described electrode cable 3,4,5 diameters are 0.2mm, barb 13 length are 1.0mm, current-carrying part 14 length of barb tip are 0.5mm.

The utlity model has following advantage: can satisfy at body and exsomatize and stride the research of ventricle wall electrophysiological characteristics animal, can be used for 1. observing special electrophysiological phenomena (as after-depolarization, 2 turn back mutually, the sequences of ventricular depolarization sequential scheduling); 2. the research of the antiarrhythmic drug electrophysiological characteristics and the mechanism of action; 3. the research of the arrhythmogenic effect of medicine is used for the developmental research of preclinical phase new drug.The completed monophasic action potential signal stabilization that is write down that studies show that, the persistent period is more than 2 hours; Can reflect the depolarization order and the multipole feature of striding ventricle wall exactly; All electrode is disposable is in place, electrodeless coming off and hemorrhage complication.

Description of drawings

Fig. 1 is this utility model electrogram electrode structure sketch map;

Fig. 2 is the structure key diagram of barb part among Fig. 1, opening and interior pipe cavity.

The specific embodiment

Describe performance of the present utility model in detail below in conjunction with accompanying drawing: but they do not constitute the restriction to this utility model protection.

1 is outer tube among the figure, and 2 is interior pipe, and 3,4,5 is electrode cable, and 6 is filled media, 7 electrode tail ends for sealing, and 8 is cavity, 9 is tee T, 10 sheath tube head ends for sealing, 11 is cavity, and 12 is opening, and 13 is barb, and 14 is barb tip.

From accompanying drawing as can be known: but this utility model topical monophasic action potential recording electrode, and it comprises outer tube 1, interior pipe 2, between outer tube 1 and the interior pipe 2 cavity 8 is arranged; There are three counter electrode leads 3,4,5 to be distributed in the cavity 8 between outer tube 1 and the interior pipe 2 respectively symmetrically and in the cavity 11 of interior pipe 2, three are positioned at cavity 8 electrode cables and pass outer tube 1 tube wall; In addition three electrode cables that are positioned at cavity 11 pass manage 2 and outer tube 1 on corresponding opening 12, the electrode tail end 7 of sealing and the sheath tube head end 10 of sealing (generally adopting the epoxy resin sealing) are arranged at the two ends of outer tube 1 and interior pipe 2, tee T 9 is arranged on the outer tube 1, tee T 9 communicates with cavity 8, be positioned on the electrode cable 3,4,5 outside the outer tube 1 barb 13 is arranged, in the interior pipe 2 filled media 6 is arranged, described filled media 6 is an agarose potassium chloride gel.Assembling rear electrode external diameter 1.67mm, three layers of myocardial lead between equidistant, distance range can be 1.0-1.6mm between the ectonexine, the filamentary silver diameter is 0.2mm, barb length is 1.0mm, barb tip length is 0.5mm.

Using method and the experimental procedure of this utility model electrogram electrode in experiment is as follows: median incision is opened breast before 1. after the Animal Anesthesia, makes the pericardium hammock, exposes the left ventricle antetheca; 2. the heart that at first punctures is determined antetheca heart thickness, and the Seldinger method is placed soft seal wire in the site of puncture, expand ventricle wall with 5F sheath tube core along seal wire; 3. extract sheath tube core and seal wire simultaneously and put into this utility model electrogram electrode of suitable length along former puncture place, having to return slightly after the sense that falls through and carrying electrode, its barb promptly firmly embeds in the ventricle wall; 4. right electrodes is a negative pole in the accompanying drawing, and left electrodes is anodal, changes the line box with the multiple tracks electrophysiology instrument and links, can record interior, in, outer three layers of monophasic action potential that cardiac muscle is stable; 5. the needs according to experimental design can be used to study the influence of medicine to the electrophysiological characteristics of three layers of cardiac muscle by the tee T local myocardial drug application of electrode.

Need to prove: to those of ordinary skill in the art, can also make some changes or distortion to this utility model under the prerequisite that does not change this utility model principle, this belongs to protection domain of the present utility model equally.

Claims

But 1 topical monophasic action potential recording electrode, it comprises outer tube (1), interior pipe (2), between described outer tube (1) and the interior pipe (2) cavity (8) is arranged; It is characterized in that having three counter electrode leads (3,4,5) to be distributed in the cavity (8) between outer tube (1) and the interior pipe (2) respectively symmetrically and in the cavity (11) of interior pipe (2), three are positioned at cavity (8) electrode cable and pass outer tube (1) tube wall; In addition three electrode cables that are positioned at cavity (11) pass the corresponding opening (12) on pipe (2) and the outer tube (1), the electrode tail end (7) of sealing, the sheath tube head end (10) of sealing are arranged at the two ends of described outer tube (1) and interior pipe (2), tee T (9) is arranged on the described outer tube (1), described tee T (9) communicates with cavity (8), described being positioned on the outer electrode cable (3,4,5) of outer tube (1) has barb (13), in the described interior pipe (2) filled media (6) arranged.
But 2, topical monophasic action potential recording electrode according to claim 1 is characterized in that the described distance that is positioned between outer tube (1) electrode cable that upward homonymy is adjacent equates.
But 3, topical monophasic action potential recording electrode according to claim 2, what it is characterized in that described electrode cable (3,4,5) is the filamentary silver that is coated with insullac outward, described electrode cable (3,4,5) diameter is 0.2mm, barb (13) length is 1.0mm, and the current-carrying part length of barb tip (14) is 0.5mm.