CN2713471Y - Reagent box for multi-index joint inspection - Google Patents
Reagent box for multi-index joint inspection Download PDFInfo
- Publication number
- CN2713471Y CN2713471Y CN 200420046022 CN200420046022U CN2713471Y CN 2713471 Y CN2713471 Y CN 2713471Y CN 200420046022 CN200420046022 CN 200420046022 CN 200420046022 U CN200420046022 U CN 200420046022U CN 2713471 Y CN2713471 Y CN 2713471Y
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- CN
- China
- Prior art keywords
- joint inspection
- index
- test strips
- utility
- detection
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- 238000007689 inspection Methods 0.000 title claims abstract description 23
- 239000003153 chemical reaction reagent Substances 0.000 title abstract description 6
- 238000012360 testing method Methods 0.000 claims abstract description 39
- 238000001514 detection method Methods 0.000 claims abstract description 32
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 6
- 238000004587 chromatography analysis Methods 0.000 claims description 5
- 238000000926 separation method Methods 0.000 claims description 3
- 201000010099 disease Diseases 0.000 abstract description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 11
- 208000030507 AIDS Diseases 0.000 description 12
- 210000004369 blood Anatomy 0.000 description 11
- 239000008280 blood Substances 0.000 description 11
- 239000000427 antigen Substances 0.000 description 9
- 102000036639 antigens Human genes 0.000 description 9
- 108091007433 antigens Proteins 0.000 description 9
- 208000002672 hepatitis B Diseases 0.000 description 9
- 210000002966 serum Anatomy 0.000 description 9
- 208000006379 syphilis Diseases 0.000 description 7
- 244000061458 Solanum melongena Species 0.000 description 6
- 208000011580 syndromic disease Diseases 0.000 description 6
- 241000700721 Hepatitis B virus Species 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 239000010931 gold Substances 0.000 description 3
- 229910052737 gold Inorganic materials 0.000 description 3
- 208000006454 hepatitis Diseases 0.000 description 3
- 231100000283 hepatitis Toxicity 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000000084 colloidal system Substances 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 238000003317 immunochromatography Methods 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model discloses a reagent box used for the multi-index joint inspection. The reagent box for the multi-index joint inspection of the utility model comprises an upper cover, a base board, and a test paper strip which is provided between the upper cover and the base board. More than one fixed slots which is mutually divided is arranged on the base board. Each slot is fixed with a test paper strip. The positions on the upper cover corresponding to each fixed slot are respectively provided with the specimen adding holes and the resulting display windows which are mutually divided. The utility model can simultaneously, rapidly and conveniently detect the quantity detecting index of one disease or one class of the disease or a plurality of similar detection index of many diseases only through one step operation. The utility model has high efficiency and convenience, and can proceed with the comprehensive analysis to the test result. Thus, the rapid and comprehensive detection with large scale is probable.
Description
Technical field
The utility model belongs to biomedical detection range, relates to a kind of detection kit.
Background technology
Along with the development of biomedical detection technique, the kit that adopts various emerging detection methods is used widely in hospital, clinic, health and epidemic prevention department also in constantly development and improvement.Because the appearance of these detection type kits, many and people live closely-related disease especially the detection quickly and easily of common transmittable disease become a reality.But present detection type kit still has the following disadvantages: at first, common most of detection type kits all are the detections of single index, and the data analyzed that obtain are single, not comprehensive, and are powerless to the detection of multinomial composite index.Secondly, the many index joint inspection kit that has gone on the market still adopts the structure of a test strips, a well, only is that test strips and well are widened, and display window as a result separated, show sample spread afterwards the reaction result at different parts on test strips respectively.This class many index joint inspection kit, requiring has enough big application of sample amount ability sufficient reacting, and the index that can detect is also limited, also is easy to generate the phase mutual interference between the reaction result.
Summary of the invention
The purpose of this utility model is to provide a kind of kit that is used for the many index joint inspection, this kit only need single stepping can be simultaneously, quick, easy detection certain or certain class disease several detect several close detection indexs of indexs or certain several disease.
Many index joint inspection kit described in the utility model, comprise loam cake, base plate and place loam cake and base plate between test strips, offer at least two pickup grooves of separating mutually on the described base plate, test strips of every groove internal fixation, the quantity of pickup groove and test strips equals the item number of joint inspection index; On cover the position corresponding and offer the well of mutual separation and display window as a result respectively with every pickup groove.
Described test strips can be an immune colloidal gold chromatography method test strip, and detection zone and control zone are arranged on it.
Many index joint inspection kit described in the utility model has the following advantages:
(1) reserved many pickup grooves that are used for fixing test strips in this kit, can settle different test strips according to the kinds of Diseases of required detection, and the number of determining test strips according to the item number of joint inspection index.Space between each pickup groove makes also space of each test strips, and the cross pollution of sample can not take place.
(2) this kit adopts separately independently well, can guarantee that the application of sample amount of each test strips is enough and even, thereby guarantees the accuracy of testing result.
(3) this kit can adopt sample injector hole difference application of sample one by one when application of sample, and also available different sample injector is to each well difference application of sample, and the application of sample amount in every hole is little, still can satisfy the detection needs, and operator's dirigibility is big.
(4) for the disease of some multinomial composite indexs,, can in a kit, finish the detection of multinomial physiochemical indice simultaneously as the detection of hepatitis B, efficiently convenient, can carry out analysis-by-synthesis to testing result, qualitative more accurate to what diagnose.
(5) can realize detecting at present the type kit some new functions that can not possess, as to the reinspection of a few indexs, several persons' to be checked sample is compared detection, primary sample separated that the different samples that obtain carry out the detection of multiple index in same kit and the test strips of different detection methods is integrated in the same kit same index is compared detection or the like in same kit, make extensive, quick, comprehensive disease detection become possibility.
Description of drawings
Fig. 1 is a synoptic diagram of the present utility model;
The result schematic diagram of Fig. 2 (a)-(b) for detecting.
Fig. 3 (a)-(b) is the another kind of result schematic diagram that detects.
Embodiment
When many index joint inspection kit described in the utility model, as shown in Figure 1, comprise loam cake 1, base plate 2 and place loam cake 1 and base plate 2 between test strips 3, offer one or more pickup groove of separating mutually 4 on the described base plate 2, test strips 3 of every groove 4 internal fixation, the position corresponding with every pickup groove 4 offers the well 5 of mutual separation and display window 6 as a result respectively on the loam cake 1.
The quantity of pickup groove 4 and test strips 3 equals the item number of joint inspection index.Pickup groove 4 shown in Figure 1 is five, can carry out the joint inspection of five indices at most.
When test strips 3 described in the utility model is immune colloidal gold chromatography method test strip, its testing result as shown in Figures 2 and 3, after sample added from well 5, react and to see from display window 6 as a result that the aubergine band appearred in detection zone (T district) 7 and control zone (C district) 8 corresponding positions in 1～2 minute.When detecting with sandwich method, shown in Fig. 2 (a),, show in blood serum/whole blood and contain test item if the aubergine band all appears in C district 8 and T district 7, be positive; Shown in Fig. 2 (b), T district 7 does not occur if the aubergine band appears in C district 8, shows in blood serum/whole blood not contain test item, is negative; When detecting with competition law, shown in Fig. 3 (a), T district 7 does not occur if the aubergine band appears in C district 8, shows in blood serum/whole blood to contain test item, is positive; Shown in Fig. 3 (b), if the aubergine band all appears in C district 8 and T district 7, show in blood serum/whole blood and do not contain test item, be negative; As long as band do not appear in C district 8, the inefficacy of expression kit or operate invalid.
Embodiment one: five indexes of hepatitis b joint inspection colloidal gold kit
The colloidal gold chromatography that the utility model is applied to the five indexes of hepatitis b conventional index detects, realize by following technical proposal: in 5 colloidal gold strip fixating reagent boxes, utilize the monoclonal antibody of colloid gold label or the hepatitis B virus surface antigen (HBsAg) in Detection of antigen blood serum/whole blood, hepatitis B surface antibody (HBsAb), hepatitis B virus e antigen (HBeAg), hepatitis B e antibody (HBeAb), hepatitis B core antibody (HbcAb) is coated in respectively on each test strips, detection zone (T district) in each test strips wraps by a hepatitis B recombinant antigen or monoclonal antibody, (C district) bag is pasted the glass fibre membrane of coated with gold mark antigen or antibody by anti-mouse antibody in the lower end of film bar in the control zone.This five indexes of hepatitis b joint inspection colloidal gold kit be utilize the competition of immunochromatography suppress method (HBeAb, HBcAb) and sandwich method (principle HBeAg) detects above-mentioned five indices simultaneously for HBsAg, HBsAb.After drawing a certain amount of blood (blood serum/whole blood) and adding, can see result at display window as a result in 1～5 minute to corresponding test item from well.Detection sensitivity can reach respectively: HBsAg (hepatitis B surface antigen) 1: 10000, HBsAb (hepatitis B surface antibody) 1: 20, HBeAg (hepatitis B virus e antigen) 1: 80, HBeAb (hepatitis B e antibody) 1: 64, HbcAb. (hepatitis B core antibody) 1: 800.
The kit that present embodiment adopts as shown in Figure 1, pickup groove 4 is five, can fix five colloidal gold strips 3, carries out the joint inspection of five indices simultaneously.
Embodiment two: acquired immune deficiency syndrome (AIDS), two joint inspection colloidal gold kits of syphilis
The colloidal gold chromatography that the utility model is applied to acquired immune deficiency syndrome (AIDS), two kinds of venereal diseases of syphilis detects, be achieved through the following technical solutions: in 2 colloidal gold strip fixating reagent boxes, detection zone (T district) in each test strips wraps respectively by the acquired immune deficiency syndrome (AIDS) antigen of colloid gold label and syphilis antigen, and wrap by anti-mouse antibody in control zone (C district).This acquired immune deficiency syndrome (AIDS), two joint inspection colloidal gold kits of syphilis are to utilize the sandwich ratio juris of immunochromatography, detect aids antibody and syphilis antibody in blood serum/whole blood, when containing acquired immune deficiency syndrome (AIDS) or syphilis antibody in blood serum/whole blood, can show an aubergine or red stripes at the detection zone (T district) of film bar; Reagent is effective, all can show a band in the control zone.Its detection sensitivity was respectively acquired immune deficiency syndrome (AIDS) 1: 1280, syphilis 1: 64.After drawing a certain amount of blood (blood serum/whole blood) and adding, can see result at display window as a result in 1～5 minute to corresponding test item from the application of sample window.
The kit that present embodiment adopts can be as shown in Figure 1, and pickup groove 4 is five, only fixes two colloidal gold strips 3, carries out the joint inspection of two indexs simultaneously.
Claims (2)
1, many index joint inspection kit, comprise loam cake (1), base plate (2) and place loam cake (1) and base plate (2) between test strips (3), it is characterized in that: offer at least two pickup grooves of separating mutually (4) on the described base plate (2), every groove (4) test strips of internal fixation (3), the quantity of pickup groove (4) and test strips (3) equals the item number of joint inspection index; Loam cake (1) is gone up the position corresponding with every pickup groove (4) and is offered the well (5) of mutual separation and display window (6) as a result respectively.
2, many index joint inspection kit according to claim 1, it is characterized in that: described test strips (3) is an immune colloidal gold chromatography method test strip, and detection zone (7) and control zone (8) are arranged on it.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200420046022 CN2713471Y (en) | 2004-05-21 | 2004-05-21 | Reagent box for multi-index joint inspection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200420046022 CN2713471Y (en) | 2004-05-21 | 2004-05-21 | Reagent box for multi-index joint inspection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2713471Y true CN2713471Y (en) | 2005-07-27 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200420046022 Expired - Lifetime CN2713471Y (en) | 2004-05-21 | 2004-05-21 | Reagent box for multi-index joint inspection |
Country Status (1)
| Country | Link |
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| CN (1) | CN2713471Y (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101915839A (en) * | 2010-08-13 | 2010-12-15 | 中南大学 | Darkroom for detecting colloidal-gold strip and using method thereof |
| CN102043043A (en) * | 2010-12-10 | 2011-05-04 | 张会生 | Multi-project biochemical test analysis integrated kit and method thereof |
| CN102768275A (en) * | 2012-07-10 | 2012-11-07 | 北京陆桥技术有限责任公司 | Staphylococcal enterotoxin assay kit, method for preparing same and application |
| CN101738470B (en) * | 2008-11-06 | 2013-04-03 | 益思美诠生物科技(上海)有限公司 | Immunochromatography method capable of simultaneously detecting various analytes |
-
2004
- 2004-05-21 CN CN 200420046022 patent/CN2713471Y/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101738470B (en) * | 2008-11-06 | 2013-04-03 | 益思美诠生物科技(上海)有限公司 | Immunochromatography method capable of simultaneously detecting various analytes |
| CN101915839A (en) * | 2010-08-13 | 2010-12-15 | 中南大学 | Darkroom for detecting colloidal-gold strip and using method thereof |
| CN102043043A (en) * | 2010-12-10 | 2011-05-04 | 张会生 | Multi-project biochemical test analysis integrated kit and method thereof |
| CN102768275A (en) * | 2012-07-10 | 2012-11-07 | 北京陆桥技术有限责任公司 | Staphylococcal enterotoxin assay kit, method for preparing same and application |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20081226 Address after: 8, litchi mountain road, Luogang District Science Town, Guangdong City, Guangzhou Province, China: 510530 Patentee after: Wondfo Biotech Co., Ltd. Address before: Guangdong city of Guangzhou Province, South China University of Technology campus Fuyuan million, zip code: 510640 Patentee before: Wang Jihua |
|
| ASS | Succession or assignment of patent right |
Owner name: GUANGZHOU WANFU BIOISYSTECH CO., LTD. Free format text: FORMER OWNER: WANG JIHUA Effective date: 20081226 |
|
| C56 | Change in the name or address of the patentee |
Owner name: GUANGZHOU WONDFO BIOTECH. CO., LTD. Free format text: FORMER NAME: GUANGZHOU WONDOFO BIOMEDICAL CO., LTD. |
|
| CP01 | Change in the name or title of a patent holder |
Address after: 510530 litchi mountain road 8, Luogang District Science City, Guangdong, Guangzhou Patentee after: Guangzhou Wandfo Biotechnology Co.,Ltd. Address before: 510530 litchi mountain road 8, Luogang District Science City, Guangdong, Guangzhou Patentee before: Wondfo Biotech Co., Ltd. |
|
| C17 | Cessation of patent right | ||
| CX01 | Expiry of patent term |
Expiration termination date: 20140521 Granted publication date: 20050727 |