CN2590599Y - Special optical fibre device for intertissue irradiation optical dynamic therapy - Google Patents
Special optical fibre device for intertissue irradiation optical dynamic therapy Download PDFInfo
- Publication number
- CN2590599Y CN2590599Y CN 02250236 CN02250236U CN2590599Y CN 2590599 Y CN2590599 Y CN 2590599Y CN 02250236 CN02250236 CN 02250236 CN 02250236 U CN02250236 U CN 02250236U CN 2590599 Y CN2590599 Y CN 2590599Y
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- Prior art keywords
- optical
- optical fiber
- butt joint
- fiber
- optic fibre
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- Expired - Lifetime
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- 239000013307 optical fiber Substances 0.000 title claims abstract description 66
- 230000003287 optical effect Effects 0.000 title claims abstract description 27
- 238000002560 therapeutic procedure Methods 0.000 title claims description 17
- 230000008878 coupling Effects 0.000 claims abstract description 5
- 238000010168 coupling process Methods 0.000 claims abstract description 5
- 238000005859 coupling reaction Methods 0.000 claims abstract description 5
- 239000000835 fiber Substances 0.000 claims description 39
- 210000001503 joint Anatomy 0.000 claims description 30
- 230000005540 biological transmission Effects 0.000 claims description 5
- 239000011521 glass Substances 0.000 claims description 4
- 238000003032 molecular docking Methods 0.000 claims description 2
- 230000001225 therapeutic effect Effects 0.000 abstract description 5
- 206010028980 Neoplasm Diseases 0.000 abstract description 4
- 230000008901 benefit Effects 0.000 abstract description 4
- 238000002428 photodynamic therapy Methods 0.000 abstract description 4
- 206010061902 Pancreatic neoplasm Diseases 0.000 abstract description 3
- 201000010536 head and neck cancer Diseases 0.000 abstract description 3
- 208000014829 head and neck neoplasm Diseases 0.000 abstract description 3
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 abstract description 3
- 230000001678 irradiating effect Effects 0.000 abstract 2
- 201000007270 liver cancer Diseases 0.000 abstract 1
- 208000014018 liver neoplasm Diseases 0.000 abstract 1
- 201000002528 pancreatic cancer Diseases 0.000 abstract 1
- 208000008443 pancreatic carcinoma Diseases 0.000 abstract 1
- 239000003822 epoxy resin Substances 0.000 description 2
- LNEPOXFFQSENCJ-UHFFFAOYSA-N haloperidol Chemical compound C1CC(O)(C=2C=CC(Cl)=CC=2)CCN1CCCC(=O)C1=CC=C(F)C=C1 LNEPOXFFQSENCJ-UHFFFAOYSA-N 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920000647 polyepoxide Polymers 0.000 description 2
- 206010005003 Bladder cancer Diseases 0.000 description 1
- 208000017897 Carcinoma of esophagus Diseases 0.000 description 1
- 206010011409 Cross infection Diseases 0.000 description 1
- 229910000881 Cu alloy Inorganic materials 0.000 description 1
- 206010029803 Nosocomial infection Diseases 0.000 description 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 description 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 230000003044 adaptive effect Effects 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 201000005619 esophageal carcinoma Diseases 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 239000003504 photosensitizing agent Substances 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 201000005112 urinary bladder cancer Diseases 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
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- Radiation-Therapy Devices (AREA)
- Laser Surgery Devices (AREA)
Abstract
The utility model relates to a special optical fiber device for inter-tissue irradiating photodynamic therapy, which comprises two segments of energy transferring optical fibers and an optical-fiber abutting device, wherein, one end of a first-segment optical fiber is provided with a cylindrical diffusing light-releasing device, and the other end of the first-segment optical fiber is an optical grinding surface; one end of a second-segment optical fiber is provided with a universal adaptor, and the other end of the optical fiber is also an optical grinding surface; the optical grinding ends of the two segments of optical fibers are directly butted in the optical-fiber abutting device to carry out optical coupling. The optical fiber segment provided with a cylindrical diffusing light-releasing device is a disposable using component, so the utility model has the advantages of convenient abutting and replacement, and low cost; compared with a traditional integral-type optical fiber device, the cost of the utility model is reduced greatly. The optical fiber device can be matched with a laser photodynamic therapeutic machine to be used for inter-tissue irradiating photodynamic therapy for human physical tumors, such as head and neck cancer, liver cancer, pancreatic cancer, etc.
Description
Technical field
This utility model belongs to a kind of medical apparatus and instruments, is specifically related to a kind of supporting special optic fibre device of tumor laser power therapeutic machine.
Background technology
Photodynamic therapy (PDT) is a new method of utilizing photosensitizer and laser activation to carry out disease treatment, is mainly used in the treatment of solid malignant at present, also is used for the treatment of some precancerous lesion and benign lesion simultaneously.
Optical dynamic therapy need be finished in two steps, at first will give the patient infusion photosensitive drug, exactly focal zone is carried out laser irradiation then.Laser irradiation is released the energy transmission optical fibre of light device termination and is finished by having difference, and radiation modality then is divided into two kinds of surface irradiation and interstitial irradiations.Surface irradiation is used for the optical dynamic therapy of the esophageal carcinoma, tracheocarcinoma, bladder cancer more, and interstitial irradiation is used for the optical dynamic therapy of head and neck cancer, hepatocarcinoma, cancer of pancreas more.
The optical fibre device that can be used for interstitial irradiation's optical dynamic therapy at present is a complete optical fiber.One end band SMA905 universal joint, the other end or truncation are exposed, perhaps are with disperse to release the light device.This optical fiber costs an arm and a leg, and is difficult to thorough disinfection.In interstitial irradiation's optical dynamic therapy, optical fiber directly contacts with tissue, for reducing the incidence rate of cross infection, and must be as the disposable articles for use that make, so very waste.Usually, to interstitial irradiation's optical dynamic therapy of big tumor, need use the optical fibre device more than 4 simultaneously, this will cause the high enterprise of medical treatment cost, be unfavorable for applying of this new technique.
For reducing the loss of optical fibre device, the someone attempts optical fiber is placed the expert interstitial irradiation of the plastic bushing optical dynamic therapy of end sealing.But this way need select very thick puncture needle to come the plastic bushing of pilot tape optical fiber to get involved, and must strengthen the penetration damage to tissue, has also strengthened simultaneously and has taken the probability that cancerous cell causes the cancerometastasis of plantation property out of.
Summary of the invention
The purpose of this utility model is to provide a kind of optical fibre device that is exclusively used in interstitial irradiation's optical dynamic therapy, significantly to reduce expending of expensive optical fibre device in interstitial irradiation's optical dynamic therapy, reduces simultaneously and takes the probability that cancerous cell causes the cancerometastasis of plantation property out of.
The interstitial irradiation's optical dynamic therapy special optic fibre device that the utility model proposes comprises: two sections multimode energy transmission optical fibres and a fiber alignment device, and the light device is released in the cylindric disperse of an end band of first section optical fiber, and the other end is the optics flat surface grinding; One end band universal joint of second section optical fiber, the other end is the optics flat surface grinding; The optics of two sections optical fiber polishes end direct butt joint in the fiber alignment device and carries out optical coupling.
Compared with prior art have following advantage and effect.
Of the present utility modelly have cylindric disperse to release the fiber segment of light device be the disposable appliance that makes, butt joint, change conveniently, inexpensive, compare with traditional monoblock type optical fibre device, cost greatly reduces.
Guaranteeing to treat under the prerequisite of reliability, this utility model is with the limited decline of Laser Transmission efficient, exchange declining to a great extent of treatment cost for, thereby help applying of interstitial irradiation's photodynamic therapy, be expected to create good social benefit and economic benefit.
This special optic fibre device can adaptive laser power therapeutic machine be used for interstitial irradiation's optical dynamic therapy of human entity tumors such as head and neck cancer, hepatocarcinoma, cancer of pancreas, has a extensive future.
Description of drawings
Fig. 1 is an exemplary embodiments structure chart of the present utility model;
Fig. 2 is another example structure figure of the present utility model;
Fig. 3 is embodiment 1 sketch map of its fiber alignment cover member;
Fig. 4 is embodiment 2 sketch maps of its fiber alignment cover member;
Fig. 5 is embodiment 3 sketch maps of its fiber alignment cover member;
Fig. 6 is embodiment 4 sketch maps of its fiber alignment cover member.
The specific embodiment
Interstitial irradiation's optical dynamic therapy special optic fibre device as shown in Figure 1 comprises: two sections core diameters are multimode energy transmission optical fibre and fiber alignment device of ￠ 200-600 micron.The fiber segment (11) that is connected with the laser power therapeutic machine, an end band SMA905 universal joint, the other end is optics flat surface grinding (12), these parts can repeatedly use; The fiber segment that contacts with tissue (13), light device (14) is released in the cylindric disperses of external diameter such as an end band and optical fiber, and the other end is optics flat surface grinding (15), and these parts are disposable use.The truncation of two sections optical fiber components polishes end and carries out optical coupling by the direct butt joint of fiber alignment device, and this fiber alignment device can repeatedly use.
Fig. 2 is another example structure figure of the present utility model.The fiber segment (21) that is connected with the laser power therapeutic machine, an end band SMA905 universal joint, the other end is optics flat surface grinding (22), these parts can repeatedly use; The fiber segment that contacts with tissue (23), light device (24) is released in the cylindric disperses of external diameter such as an end band and optical fiber, and the other end is optics flat surface grinding (25), and these parts are disposable use.The optics of two sections optical fiber components polishes end and carries out optical coupling by the direct butt joint of fiber alignment device, and this fiber alignment device can repeatedly use.
The fiber alignment device has two kinds of embodiment.In embodiment 1 (Fig. 1,3), the fiber alignment device is made of a butt joint cover (16), two rubber washers (17,17 ') and two fastening nuts (18,18 ').The two ends band pin thread of butt joint cover, the fastening nut that is spirally connected respectively, and a rubber washer is set with docking to overlap between the respective end at each fastening nut.
The two-port (33,33 ') of the optical-fibre channel in the described butt joint cover (16) is horn-like, and optical-fibre channel (32) diameter is identical with the optical fiber external diameter.Two rubber washers (17,17 ') place the two-port (33,33 ') of butt joint unjacketed optical fiber passage to locate respectively, its external diameter be slightly less than the butt joint cover external diameter, internal diameter is slightly less than the external diameter of used optical fiber.Two fastening nuts (18,18 ') place respectively outside the butt joint cover two ends rubber washers (17,17 '), nut one sideband and the female thread that docks the cover same specification, and the circular hole (19) that a diameter equates with the optical fiber external diameter is opened at the another side center.During use, the optics that will be connected to the optical fiber components of optical dynamic therapy machine earlier polishes end successively by a fastening nut, a rubber washer, is advanced to the optical-fibre channel center from butt joint cover one end carefully, and appropriateness screws fastening nut; The optics of the optical fiber components that will contact with tissue polishes end successively by another fastening nut and another rubber washer then, be advanced to when meeting obstructions from the butt joint cover other end carefully and stop, appropriateness screws fastening nut under the situation that keeps slight propelling pressure.
In embodiment 2 (Fig. 2,4), the fiber alignment device is made of a butt joint cover (26), a rubber washer (27) and a fastening nut (28); One end band pin thread (41) of butt joint cover, its central shaft to optical-fibre channel (42) diameter identical with the optical fiber external diameter, optical-fibre channel is with the outlet of pin thread one end (43) to be horn-like at the butt joint cover.The optics of the optical fiber components that is connected with the optical dynamic therapy machine polishes end, is not advanced to the optical-fibre channel center with an end of pin thread from butt joint cover, composes one with dock to overlap then.With the optical-fibre channel exit that a rubber washer (27) places the butt joint cover to be with pin thread one end, its external diameter is slightly less than the external diameter of butt joint cover, and internal diameter is slightly less than the external diameter of used optical fiber.A fastening nut (28) places outside the rubber washer of butt joint cover band pin thread one end, nut one sideband and the female thread that docks the cover same specification, and the circular hole (29) that a diameter equates with the optical fiber external diameter is opened at the another side center.During use, the optics of the optical fiber components that will contact with tissue polishes end successively by fastening nut and rubber washer, be advanced to when meeting obstructions from butt joint unjacketed optical fiber passage open end carefully and stop, appropriateness screws fastening nut under the situation that keeps slight propelling pressure.
Fig. 3,4 fiber alignment are applied mechanically the cylindrical, copper alloy material and are processed by aforementioned configuration requirement.In Fig. 5,6, butt joint is applied mechanically one section thin glass tube (51,61) outer cover ring epoxy resins (52,62) and is processed by aforementioned requirement to required external diameter, the thin glass tube outer wall is through the gummed power of frosted processing with increase and outer cover ring epoxy resins, its inner duct is optical-fibre channel (32,42), the optical-fibre channel diameter is identical with used optical fiber external diameter, and the port of export of movable grafting optical fiber (33,33 ', 43) all is horn-like.
Claims (10)
1, a kind of interstitial irradiation optical dynamic therapy special optic fibre device is characterized in that comprising two sections multimode energy transmission optical fibres and a fiber alignment device, and the light device is released in the cylindric disperse of an end band of first section optical fiber, and the other end is the optics flat surface grinding; One end band universal joint of second section optical fiber, the other end is the optics flat surface grinding; The optics of two sections optical fiber polishes end direct butt joint in the fiber alignment device and carries out optical coupling.
2, special optic fibre device according to claim 1 is characterized in that: the core diameter of described two sections optical fiber is ￠ 200-600 micron.
3, special optic fibre device according to claim 1 and 2 is characterized in that: external diameters such as light device and optical fiber are released in described cylindric disperse.
4, special optic fibre device according to claim 1 and 2 is characterized in that: the universal joint of described second section fibre ribbon is the SMA905 joint.
5, special optic fibre device according to claim 1, it is characterized in that: described fiber alignment device contains a butt joint cover, the two ends band pin thread of butt joint cover, the fastening nut that is spirally connected respectively, and a rubber washer is set with docking to overlap between the respective end at each fastening nut.
6, special optic fibre device according to claim 5 is characterized in that: the two-port of the optical-fibre channel in the described butt joint cover is horn-like.
7, special optic fibre device according to claim 5 is characterized in that: the optical-fibre channel in the described butt joint cover adopts thin glass tube.
8, special optic fibre device according to claim 1 is characterized in that: described fiber alignment device contains a butt joint cover, an end band pin thread of butt joint cover, and the fastening nut that is spirally connected, and a rubber washer is set betwixt.
9, special optic fibre device according to claim 8 is characterized in that: the port of the optical-fibre channel of described butt joint cover threaded end is horn-like.
10, special optic fibre device according to claim 8 is characterized in that: the optical-fibre channel in the described butt joint cover adopts thin glass tube.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02250236 CN2590599Y (en) | 2002-12-10 | 2002-12-10 | Special optical fibre device for intertissue irradiation optical dynamic therapy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02250236 CN2590599Y (en) | 2002-12-10 | 2002-12-10 | Special optical fibre device for intertissue irradiation optical dynamic therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2590599Y true CN2590599Y (en) | 2003-12-10 |
Family
ID=33720500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02250236 Expired - Lifetime CN2590599Y (en) | 2002-12-10 | 2002-12-10 | Special optical fibre device for intertissue irradiation optical dynamic therapy |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2590599Y (en) |
-
2002
- 2002-12-10 CN CN 02250236 patent/CN2590599Y/en not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee | ||
| CP03 | Change of name, title or address |
Patentee address after: 518038 Cotton Tree Drive in Guangdong province Shenzhen Futian Free Trade Zone No. 8, Yingdali technology digital park C building 311 Patentee address before: 518057 Guangdong city of Shenzhen province Nanshan District high tech Industrial Park in the Southern District Comprehensive Building 3 floor 30142 |
|
| C17 | Cessation of patent right | ||
| CX01 | Expiry of patent term |
Expiration termination date: 20121210 Granted publication date: 20031210 |