CN2574057Y - Blood group identifying reagent kit - Google Patents
Blood group identifying reagent kit Download PDFInfo
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- CN2574057Y CN2574057Y CN 02248986 CN02248986U CN2574057Y CN 2574057 Y CN2574057 Y CN 2574057Y CN 02248986 CN02248986 CN 02248986 CN 02248986 U CN02248986 U CN 02248986U CN 2574057 Y CN2574057 Y CN 2574057Y
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- blood group
- antibody
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- reaction cup
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Abstract
The utility model relates to a blood group identifying reagent box which comprises a plurality of reagent units. In the utility model, each reagent unit comprises three reaction cups which are longitudinally connected; the inner parts of the three reaction cups are respectively provided with an ABO blood group antibody A, an ABO blood group antibody B and a Rh blood group antibody D; the inner parts of the ABO blood group antibody A, the ABO blood group antibody B and the Rh blood group antibody D are provided with magnetic beads which cover the antibodies; a plurality of the reagent units are connected with each other into integration; the opening surfaces of the reagent units are stuck with sealing gummed paper or aluminium foil. The utility model combines an ABO group system and a Rh blood group system into one unit, can simultaneously detect ABO blood group and Rh blood group, adopts epoxy activated magnetic beads for covering blood group substances (antibodies) and increases antigen antibody combining points causing antigen antibody agglutination reaction to be obviously and specially displayed for preventing the occurrence of false negative. The utility model has the advantages of high agglutination reaction specificity, high sensitivity and good effect of agglutination reaction and enhances the accuracy rate of blood group identification.
Description
Technical field
The utility model relates to medicine equipment, specifically is the blood group identification kit that a kind of hospital, blood transfusion mechanism use.
Background technology
It is routine clinical test item that blood group is identified, is the most normal Interventions Requested of doing of hospital laboratory, also is the project of the essential check of clinical emergency call salving blood transfusion.Traditional method has two kinds: slide agglutination (scraps of paper agglutination) and test tube centrifuge method.Slide agglutination is one of the most frequently used method of present each hospital.This method manual operations is easy, but must remove to shake slide by hand one by one, wastes time and energy.The paper disk method principle is the same with slide method, but it can make 10 samples on a piece of paper sheet, and also sample is done one by one.Paper disk method is suitable for batch operation and detects.But paper disk method is easily dry at room temperature, is unfavorable for observing repeatedly check.Test tube centrifuge method complex operation, be one by one in hydro-extractor the centrifuging precipitation, shake up and observe the agglutinating reaction situation, can not be applicable to large batch of detection, clinically only be used for indivedual slide agglutinations and identify that blood groups further identify check at need.As anemia patient specimen, tumour patient or myeloma patient sample, leukemia patient sample etc., the result of slide agglutination observes judgement and often more easily makes mistakes.Standard serum is tired and is reduced or observation that affinity is slide agglutination (paper disk method) result when strong is judged and also more easily made mistakes.Because anti-A, anti-B and A type, Type B are very easily obscured on notion consciousness, in the process that adds blood group diagnose reagent preparation (standard serum) respectively, and when observing judged result, often cause the illusion on the notion consciousness easily, cause blood group to identify mistake.
Summary of the invention
The problems referred to above in view of existing blood group authenticate technology exists the utility model proposes a kind of disposable blood group identification kit, identify accuracy rate with the efficient and the blood group that improve blood group evaluation work.
This blood group identification kit, comprise some reagent unit, each reagent unit contains three reaction cup, three reaction cup vertically link to each other, place the anti-A of abo blood group, anti-B and the anti-D of Rh blood group in three reaction cup respectively, all place the magnetic bead of coated antibody in the anti-A of described abo blood group, anti-B and the anti-D of Rh blood group; Some reagent unit are connected with each other and are integral, and its opening surface is pasted with cellophane tape or aluminium foil.This blood group identification kit is combined in a unit with ABO blood group system and Rh blood group system, can detect abo blood group and Rh blood group simultaneously.
This blood group identification kit compact conformation retracts conveniently, and is easy and simple to handle, applying flexible, can satisfy the demand of different amount detections to greatest extent, both sample was done one by one, can carry out batch detection again, be convenient to observe and judge, be convenient to check, effectively improved work efficiency.
Adopt epoxy activation magnetic bead bag by blood group substance (antibody), increase the antigen-antibody binding site, it is obviously special that the antigen-antibody agglutinating reaction is manifested, and can prevent false-negative generation.Agglutinating reaction specificity height, highly sensitive, agglutinating reaction is effective, has improved the accuracy rate that blood group is identified.
Blood group identifies that box belongs to the disposable hygienic material, can effectively prevent inside-hospital infection.Need not special-purpose assorted equipment by box and use this blood group to identify, cost is very low.
Description of drawings
Fig. 1 is a structural representation of the present utility model;
Fig. 2 is the vertical view of Fig. 1;
Fig. 3 is the A-A cut-open view of Fig. 1.
Embodiment
Below in conjunction with the embodiment accompanying drawing the utility model is further specified.
Blood group identification kit as Figure 1-3, comprise some reagent unit, each reagent unit contains three reaction cup 1,2,3, three reaction cup vertically link to each other, some reagent unit are connected with each other and are integral, adjacent reaction cup links to each other by dowel 5 in its opening edge, and its opening surface is pasted with cellophane tape or aluminium foil 4.
Place the anti-A11 of AB0 blood group, anti-B21 and the anti-D31 of Rh blood group in three reaction cup 1,2,3 of each reagent unit respectively, place the magnetic bead 12 of coated antibody in the described anti-A11, place the magnetic bead 22 of coated antibody in the described anti-B21, place the magnetic bead 32 of coated antibody in the anti-D31 of described Rh blood group.Magnetic bead the 12,22, the 32nd, epoxy activation magnetic bead.Adopt epoxy activation magnetic bead bag by blood group substance (antibody), increase effective surface area, blood group substance (antibody) is fully wrapped to be advanced in the reaction cup hole, increase the binding site of antigen-antibody, antigen-antibody is fully reacted, and it is obviously clear that the antigen-antibody agglutinating reaction is manifested, and agglutinating reaction is respond well, the agglutinating reaction high specific is easy to observe and judges.
This blood group identification kit is the raw material injection mo(u)lding with the polystyrene, and the reaction cup oral area is bigger, and adjacent reaction cup links to each other by dowel 5 in its opening edge, reaction cup such as common tea cup-shaped, and the bottom is flat.The pre-bag of difference is by good different blood group substance (antibody) in the reaction cup hole, and anti-A, anti-B do the visible marking with different colors and printed words in blood group evaluation box reacting hole periphery respectively with anti-D, are green as anti-A, and anti-B is yellow, and anti-D is a brown etc.
The blood group identification kit can be designed to contain the product of 8-24 reagent unit during concrete the making.Fig. 1 embodiment forms a unit by the anti-B of the anti-A of abo blood group and the anti-D3 of Rh blood group cup hole, forms a box blood group identification kit in totally 36 cup holes by 12 unit.After bag is by blood group substance (antibody), handle in the reaction cup hole, eliminate and disturb through sealing technique.Seal paper or aluminium foil 2 seals with viscose glue, packing is dispatched from the factory.
In the time of need doing the blood group evaluation, the quantity that the root a tree name need detect what and retract blood group and identify several unit of box reaction cup, place the reaction frame, in anti-A, anti-B and anti-D reaction cup hole, add one of patient blood respectively, shook one minute through vibration, the red cell agglutination phenomenon that detects by an unaided eye can be judged blood group.
Can effectively prevent the false-negative generation that causes because of antigen amount surplus or antigen quantity not sufficient.Because the reacting hole endoperidium has the antibody of q.s, even in clinical use, run into patient specimen as anemia, tumour patient sample or myeloma patient sample etc., also the possibility that false negative occurs can be reduced to bottom line fully, the specificity of agglutinating reaction is much higher more than traditional slide agglutination and test tube centrifuge method.This blood group identifies that the bag of box is a species specificity height by serum antibody, the height of tiring, and affinity is strong, and has than high specific acitivity.Be a kind of high specific, highly sensitive blood group authentication method.
This blood group identification kit is disposable, can effectively prevent inside-hospital infection.Adopt traditional slide method or test tube method, all there is the custom of using the slide test tube repeatedly in each hospital, thereby has the potential danger of cross pollution inevitably, has the possibility of inside-hospital infection.From effectively preventing the purpose requirement of inside-hospital infection, should encourage to use the application of disposable hygienic material in clinical position energetically.
Traditional slide agglutination or test tube centrifuge method, to indicate A or B printed words respectively, and add corresponding standard serum respectively, and then add patient specimen respectively, through vibration shake or hydro-extractor centrifugation after, observe red cell agglutination through visual inspection or microscopically and judge blood group.And wrapped by the anti-A of good blood group substance (antibody), anti-B and anti-D in this blood group evaluation box reaction cup, and use different colouring discriminations respectively, be provided with A, B, D blood group printed words in blood group identification kit reaction cup periphery, very easily identification.These operations are finished on streamline in the production run of product in proper order.When doing the blood group evaluation, operating personnel only need to identify adding patient specimen in the box reaction cup hole toward blood group that after vibration was shaken, the visual inspection red cell agglutination can be judged blood group.Can reduce the mistake of manual operation factor and sentence read result to greatest extent, improve the accuracy rate that blood group is identified.
Claims (5)
1, a kind of blood group identification kit, it is characterized in that: comprise some reagent unit, each reagent unit contains three reaction cup, three reaction cup vertically link to each other, place the anti-A of abo blood group, anti-B and the anti-D of Rh blood group in three reaction cup respectively, all place the magnetic bead of coated antibody in the anti-A of described abo blood group, anti-B and the anti-D of Rh blood group; Some reagent unit are connected with each other and are integral, and its opening surface is pasted with cellophane tape or aluminium foil.
2, according to the described blood group identification kit of claim 1, it is characterized in that: described magnetic bead is an epoxy activation magnetic bead.
3,, it is characterized in that it comprises 8-24 reagent unit according to the described blood group identification kit of claim 1.
4, according to the described blood group identification kit of claim 1, it is characterized in that: anti-A, anti-B use different colouring discriminations respectively with anti-D in the reaction cup.
5, according to the described blood group identification kit of claim 4, it is characterized in that: the reaction cup periphery is provided with A, B, D blood group printed words.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02248986 CN2574057Y (en) | 2002-10-25 | 2002-10-25 | Blood group identifying reagent kit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02248986 CN2574057Y (en) | 2002-10-25 | 2002-10-25 | Blood group identifying reagent kit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2574057Y true CN2574057Y (en) | 2003-09-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02248986 Expired - Fee Related CN2574057Y (en) | 2002-10-25 | 2002-10-25 | Blood group identifying reagent kit |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2574057Y (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007028290A1 (en) * | 2005-09-09 | 2007-03-15 | Yong Li | A method for preserving human cell membrane antigen and human cell membrane antigen coated with magnetic particle |
| CN102520183A (en) * | 2011-10-20 | 2012-06-27 | 上海裕隆生物科技有限公司 | Sealed protein film chip |
| CN102680717A (en) * | 2012-05-30 | 2012-09-19 | 江苏力通生物技术有限公司 | Internal quality control kit for detecting transfusion compatibility and production process thereof |
-
2002
- 2002-10-25 CN CN 02248986 patent/CN2574057Y/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007028290A1 (en) * | 2005-09-09 | 2007-03-15 | Yong Li | A method for preserving human cell membrane antigen and human cell membrane antigen coated with magnetic particle |
| CN102520183A (en) * | 2011-10-20 | 2012-06-27 | 上海裕隆生物科技有限公司 | Sealed protein film chip |
| CN102680717A (en) * | 2012-05-30 | 2012-09-19 | 江苏力通生物技术有限公司 | Internal quality control kit for detecting transfusion compatibility and production process thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20030917 Termination date: 20101025 |