CN2537413Y - Pocket intelligent multiple parameter external gastro intestine phisiologic pacemaker - Google Patents
Pocket intelligent multiple parameter external gastro intestine phisiologic pacemaker Download PDFInfo
- Publication number
- CN2537413Y CN2537413Y CN 02222253 CN02222253U CN2537413Y CN 2537413 Y CN2537413 Y CN 2537413Y CN 02222253 CN02222253 CN 02222253 CN 02222253 U CN02222253 U CN 02222253U CN 2537413 Y CN2537413 Y CN 2537413Y
- Authority
- CN
- China
- Prior art keywords
- circuit
- signal
- pacemaker
- output
- mouth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Landscapes
- Electrotherapy Devices (AREA)
Abstract
The utility model relates to a pocket, intelligent, and multi-parameter vitro gastrointestinal physiologic pacemaker, comprising a microcontroller circuit, a digital-analog conversion circuit, a filter circuit, a signal buffering and analog amplifying circuit, a display circuit, a keyboard circuit, a watchdog circuit, a power supply circuit, a plurality of electrode wires for output and a plurality of low-frequency medical electrode slices for body surface compress, wherein the digital-analog conversion circuit is used for converting the digital waveform output by the control circuit, the signal buffering and analog amplifying circuit is used for impedance match to the analog output signal, and the watchdog circuit is used for supplying reliable reset and program monitor for the control circuit. The utility model is characterized in that a microcontroller 89C51 is the core. The utility model has the advantages of high intelligent degree, flexible and convenient parameter modification, generation of electric physiologic pacing stimulation signal being more similar to the pacing of the gastrointestinal cell, low manufacture cost, strong practicability, compact size, light weight, and easy operation.
Description
Technical field
This utility model relates to a kind of Medical Instruments, and the played gastrointestinal physiology pace-making of the intelligent multiparameter selection mode of particularly a kind of pocket and the instrument of gastrointestinal function regulating action belong to electronic medical equipment manufacturing technology field.
Technical background
Main both at home and abroad at present employing Drug therapy gastrointestinal dysfunction disease etc., but to some gastrointestinal function disease, Chinese and western medicine does not all have specific drug, and side effects of pharmaceutical drugs are big, the expense costliness.The someone relates to the development work of gastrointestinal pacemaker therapy and therapeutic instrument both at home and abroad in recent years.Abroad, there is the scholar to adopt percutaneous endoscopic mucosa electrode or peritoneoscope serous coat electrode to implement gastrointestinal pacemaker, Berger in 1966 etc. once used intestinal stimulator or artificial " pacemaker " to experimentizing property of gastrointestinal postoperative patient gastrointestinal pacemaker, and explored the influence of gastrointestinal pacemaker to digestive tract power; The circular cone build dipole computer model of application simulation gastric electrical activities such as Mintchev in 1997 carries out the stomach pace-making, brings out around the shape stomach and shrinks; Patient after Familoni adopts the implantable gastrointestinal pacemaker to stomach fistulation intubation carries out pacing therapy, improves the postoperative symptom.But it is traumatic that said method itself has, and the part easily causes infection, and the patient is difficult for accepting.At home, portable gastrointestinal electric artificial pacemaker as the CN95118078.9 patent application, it has overcome the shortcoming of gastrointestinal pacemaker in the insertion type body, but its function singleness, disposable stimulation mode is less, adjustable stimulus parameter is less, can not satisfy the needs of different gastrointestinal dysfunction disease patients to gastrointestinal physiology pace-making; Adopt hardware to control,, regulate inconvenient the modification of output pacing signal; The specification requirement height, the cost of manufacture height, price is higher; Though " portable " gastrointestinal pacemaker by name in addition, volume is big, weight is not light, is not easy to carry.In addition, someone once adopted other gastrointestinal electric therapeutic instrument to treat this type of disease, apparatus for regulating gastrointestinal function as the CN00111700 patent application, the gastric motility disorder medical instrument of CN97244219 patent application, the gastric ulcer of CN2045268U patent application and gastrointestinal disease apparatus for diagnosis and therapy, the gastritis direct current therapy unit of CN2030486U patent application etc., but the principle of their institute's foundations is not gastrointestinal pacemaker theory and " resonance " principle, do not directly act on gastrointestinal pacemaker cell, can not correct unusual gastrointestinal basic electrical rhythm, so can not make gastroenteritic power function recover normal preferably.
The purpose of this utility model is: the external gastrointestinal physiology pacemaker that the intelligent multiparameter selection mode of a kind of pocket is provided, it has, and intelligent degree is higher, the parameter correction is flexible, can produce the more electric physiology pacing stimulation signal near the gastrointestinal cell pace-making; It is cheap to have cost of manufacture, and utilitarian function is powerful, pocketization of volume, weight characteristics lighter, easy and simple to handle.
Summary of the invention
This utility model is with the gastrointestinal pacemaker theory, " follow " effect theory, gastrointestinal electricity physiological theory, gastrointestinal motility physiology and pathology are foundation, and utilize modern electronic technology (to simulate as computer programming, frequency synthesis techniques etc.) simulation produces " driving " signal similar to normal person's gastrointestinal bio-electric phenomenon, this " driving signal " sticks electrode slice (electrode slice is attached to the projection position of gastrointestinal pacemaker at abdomen body-surface) by the medical body surface of intrasonic and acts on the gastrointestinal pacemaker and make its produce " following resonance " effect (promptly within the specific limits, the rhythm and pace of moving things of gastrointestinal pacemaker can change along with the variation of " driving " electric field rhythm and pace of moving things that adds), thereby correct the unusual gastrointestinal electricity rhythm and pace of moving things or the electrical activity of inhibition ectopic pacemaker, impel gastrointestinal to produce enough effectively rhythmicity contraction and ahead running, alleviate or eliminate the symptom of gastrointestinal dysfunction.
Proved that now human stomach pacemaker is positioned at the zone of body of stomach middle part apart from cardia 5～7cm, the small intestinal pacemaker is positioned at duodenum apart from the about 4cm of pylorus place, and also prove that this zone has pacemaker cell to exist, these pacemaker cells are the Cajal Interstitial cells that are positioned at vertical position, circular muscle boundary and next side of inner layer ring muscularis mucosae, its frequency of oscillation is the highest, can drive the lower remote part of frequency of oscillation and produce " resonance ", promptly follow highest frequency and do synchronous vibration, and coordinate the activity of gastrointestinal each several part thus.Gastral smooth muscle cell has autorhythmicity, and whole day can record spontaneous, slow, the rhythmicity depolarization wave that takes place, i.e. basic electrical rhythm or pacemaker current potential or slow wave in 24 hours on the basis of resting potential.Normal person's the slow wave rhythm and pace of moving things is more fixing, and stomach is that 2.4cpm～3.7cpm, duodenum are 8.0cpm～12.0cpm, and nearly section jejunum is 10.8cpm.When gastrointestinal dysfunction, can occur that the rhythm and pace of moving things is overrun, the rhythm and pace of moving things is slow excessively, irregularity of pulse or the ectopic pacemaker companion occurs or do not accompany the conduction of driving in the wrong direction, the slow wave amplitude reduces, and slow wave potential loses phenomenons such as Rhizoma Nelumbinis connection, spread speed slow down.Slow wave claims the electric control activity again, it is the control wave of the smooth muscle contraction rhythm and pace of moving things, the excited threshold value that control is shunk, make smooth muscle accept external irritant and cause contraction, and position, direction, the rhythm and pace of moving things, the speed of decision gastrointestinal peristalsis, but slow wave can not directly cause the contraction of gastrointestinal smooth muscle, has only the contraction that could trigger smooth muscle behind a series of spike potentials of stack on the descending branch of slow wave or the platform, and the intensity of contraction and tension force are directly proportional with the frequency and the amplitude of spike potential.Lack as spike potential, gastrointestinal shrinks and promptly lacks as or faint reaction only arranged.Proposed the conception of the gastrointestinal physiology pace-making of multiparameter selection, non-linear space-time simulation gastrointestinal bio electricity and feedback effect reach and recover or the activity of change gastrointestinal function in the gastrointestinal pacemaker, alleviate or symptomatolytic purpose for this reason.
Animal experiment proves: according to the bioelectric result of the non-linear space-time simulation gastrointestinal of computer, adopt different synthetic " driving " waveform of serial burst pulse ripple of sinusoidal wave stack two-stage dutycycle, and adopt " driving " function of current of being somebody's turn to do the load of " driving " waveform in the gastrointestinal pacemaker, the result significantly increases the gastric emptying rate of diabetic gastroparesis model dog, the unusual gastrointestinal electricity rhythm and pace of moving things is corrected, and the clinical symptoms of gastroparesis is also obviously improved.
Based on above-mentioned conclusion, it is core that the external gastrointestinal physiology of the intelligent multiparameter of pocket pacemaker adopts 8 single-chip microcomputers, realize having sinusoidal wave by software programming and reach the synthetic waveform that stack thereon meets the two-stage burst pulse of gastrointestinal electricity physiology pace-making, through D/A converter, convert the analogue signal of certain frequency and amplitude to, amplify the back as gastrointestinal electricity physiology pacing signal.Because this core is software, so can conveniently regulate pulse number, pulse frequency and the amplitude of frequency, amplitude and synergetic impulse wave of class sinusoidal fundamental wave and the expansion of realization multifunction.
The technical solution of the utility model is as follows:
The external gastrointestinal physiology of the intelligent multiparameter of pocket pacemaker is a core with microcontroller 89C51, comprise portable enclosure, microcontroller circuit, the D/A converting circuit that the digital waveform of control circuit output is changed, the analog waveform of logarithmic mode change-over circuit output carries out the filter circuit of low-pass filtering, analog output signal is carried out the signal damping and the analog amplify circuit of impedance matching, to the waveform catalog of microcontroller circuit output and the display circuit of parameter demonstration, receive the keyboard circuit of parameter adjusting and waveform selection etc., " house dog " circuit of reliable reset and program monitoring is provided for control circuit, for above-mentioned all circuit provide the power circuit of power supply, and the electrode wires and the medical intrasonic body surface of output stick compositions such as electrode slice.
Wherein the P2 mouth of the microprocessor U1 of microcontroller directly is connected with the digital to analog converter data input pin.D/A converting circuit comprises digital to analog converter U2 and double operational U3A, constitutes the unipolarity analog to digital conversion circuit of direct-passing mode, and the digital signal that microcontroller U1 is sent here through P2 converts analogue signal (negative value) to, and is simple in structure.The analogue signal of D/A converting circuit output links to each other with filter circuit, filters high-frequency signal by filter circuit.Filter circuit links to each other with amplifying circuit of analog signal with signal damping, and signal is amplified becomes the electrophysiological stimulation signal that suits the requirements, and is input to medical intrasonic body surface at last and sticks on the electrode slice.The P0 mouth of microprocessor links to each other with J1 as LCD MODULE data presented transmission mouth, and J1 is connected to display module, carries out split screen demonstration, function selecting and parameter and regulates.Keyboard circuit links to each other with the P1 mouth of microprocessor U1, and keyboard circuit adopts scan mode, receives parameter adjusting, function selecting, stimulus waveform selection and modification." house dog " circuit output links to each other with reset terminal 9 feet of microcontroller U1, and microcontroller intermediate range sort run is monitored and the electrification reset pulse is provided, and program is brought into operation.Power circuit provides required power supply for above each circuit, adopts the integrated power supply module, accepts the input of " No. 5 " aneroid battery voltage, output+5V ,-5V ,-the 24V working power.
In the software design, at first determine the several Key Points of sinusoidal wave, set up the piecewise function of sinusoidal wave by piecewise fitting, determine to send in the one-period and count the quantity of touching data converted point, according to the parameter input of keyboard determine whether to superpose two-stage burst pulse and stack situation; According to parameters such as the frequency of keyboard input and amplitudes, determine to be input to the size and the interval of the digital quantity of digital to analog converter, deliver to the analog signal waveform that meets gastrointestinal electricity physiology pace-making that D/A converting circuit produces the sinusoidal and stack two-stage burst pulse of the class of certain amplitude, frequency; Microcontroller send keypad information the display part to show simultaneously, forms man machine interface, is convenient to regulate and function selecting.The analogue signal of D/A converting circuit output is amplified through the two-stage direct current amplifier, outputs to electrode as pacing signal.
The external gastrointestinal physiology of the intelligent multiparameter of pocket pacemaker compared with prior art, first, with the single-chip microcomputer is core, can select the output of different types of stimulus waveform as required, and can carry out flexible to the waveform and the parameter (amplitude, frequency, quantity) of the stimulus signal of output; The second, adopt modular power and modular LCD (LCM), and the D/A converting circuit of direct-passing mode; Keyboard adopts " a key multipotency ", and film key rationalizes layout and setting, and quantity is few, and function is strong, and is easy to use, makes volume littler, cheap; The 3rd, in circuit, adopted " house dog " circuit, make the program operation more reliable, reduce and disturb; In addition, circuit is succinct, working stability.Above characteristics have fully satisfied pocketization, intellectuality, strong, the portable requirement of function, and can be more targeted to different patients, and effect is better.It has overcome the shortcoming of interior gastrointestinal pacemaker of insertion type body and domestic existing gastrointestinal pacemaker, is suitable for vast different medical unit and extensive patients and uses and clinical expansion.
After this gastrointestinal pacemaker acts on the gastrointestinal pacemaker, promote gastrointestinal emptying on the one hand, regulate the gastrointestinal endocrine function on the other hand again, and make gastrointestinal recover normal physiological function.Zoopery and preliminary clinical trial all prove, adopts this instrument to carry out the stomach pace-making and can correct the unusual stomach electricity rhythm and pace of moving things that causes because of atropine and glucagon, patient's gastric emptying rate obviously increased, gastrointestinal dysfunction transference cure or alleviation.
This product is mainly used in treatment gastrointestinal dysfunction disease, as gastroptosis, diabetic gastroparesis syndrome, functional dyspepsia, postoperative gastric bowel dysfunction syndrome, gastrointestinal rhythm disturbance syndrome etc., also can be used for accompanying the superficial gastritis of dysfunction and atrophic gastritis, irritable bowel syndrome, habitual constipation, bile reflux gastritis, gastric volvulus, achalasia of the cardia etc.
Description of drawings
Fig. 1 is the circuit block diagram of the external gastrointestinal physiology of the intelligent multiparameter of pocket pacemaker;
Fig. 2 is microcontroller circuit, analog to digital conversion circuit and keyboard circuit and the display interface schematic diagram of the external gastrointestinal physiology of the intelligent multiparameter of pocket pacemaker;
Fig. 3 is the buffering and the amplifying circuit schematic diagram of the external gastrointestinal physiology of the intelligent multiparameter of pocket pacemaker;
Fig. 4 is intelligent multiparameter external gastrointestinal physiology pacemaker " house dog " circuit theory diagrams of pocket;
Fig. 5 is the power module figure of the external gastrointestinal physiology of the intelligent multiparameter of pocket pacemaker;
The specific embodiment
Be described in detail below in conjunction with the concrete enforcement of accompanying drawing the external gastrointestinal physiology of the intelligent multiparameter of pocket pacemaker.
Embodiment: the external gastrointestinal physiology of the intelligent multiparameter of pocket pacemaker comprises microcontroller circuit, D/A converting circuit and filter circuit, buffering and amplifying circuit, " house dog " circuit and keyboard circuit and display part.Fig. 1 is the circuit structure block diagram of the external gastrointestinal physiology of the intelligent multiparameter of pocket pacemaker, comprise microcontroller circuit, the D/A converting circuit that the digital waveform of control circuit output is changed, the analog waveform of logarithmic mode change-over circuit output carries out the filter circuit of low-pass filtering, analog output signal is carried out the signal damping and the amplifying circuit of analog signal of impedance matching, to the waveform catalog of microcontroller circuit output and the display circuit of parameter demonstration, receive the keyboard circuit of parameter adjusting and waveform selection etc., " house dog " circuit of reliable reset and program monitoring is provided for control circuit.Microcontroller circuit produces the pacing signal that needs, and receives keyboard parameter, is responsible for the demonstration of parameter, and the pacing signal that generation suits the requirements delivered to digital to analog converter conversion, become analogue signal, after delivering to buffer and amplifier and amplifying, output to electrode wires as pacing signal.
Fig. 2 is microcontroller circuit, D/A converting circuit and keyboard circuit and the display interface schematic diagram of the external gastrointestinal physiology of the intelligent multiparameter of pocket pacemaker, is the core that this instrument is realized.Generate the sinusoidal stimulus signal of class and described synthetic " driving " waveshape signal as requested by microcontroller U1, and select to produce different types of stimulus signal and send the display part to finish demonstration, and signal is sent into digital to analog converter conversion by keyboard.Wherein the P2 mouth of U1 (89C51) directly is connected with analog-digital converter, the P0 mouth is as LCD MODULE LCD data presented transmission mouth, link to each other with J1, J1 is connected to display module, and the WR of U1, RD, P2.6, P2.7 link to each other with display interface J2 through not gate U5A, U5B, U5C.Keyboard circuit links to each other with the P1 of U1, from keyboard input waveform catalog, and function selecting, parameter adjustment, and handle by U1.D/A converting circuit comprises digital to analog converter U2 (DAC0832) and double operational U3A (NE5532), constitutes the unipolarity D/A converting circuit of direct-passing mode, and it is simple in structure that the digital signal that microcontroller U1 is sent here through P2 converts analogue signal (negative value) to.The CS of U2, WR1, WR2, Xfer hold direct ground connection; Signal after the U2 conversion outputs to 2,3 inputs of amplifier U3A from 11,12 ends, and 9 feet of U2 link to each other with output 1 foot of amplifier U3A, constitute the D/A converting circuit that leads directly to; The analogue signal of output is delivered to filter circuit C3, filters high-frequency signal, sends into the signal that amplifier amplifies becomes needs.
Fig. 3 is the buffering and the amplifying circuit schematic diagram of the external gastrointestinal physiology of the intelligent multiparameter of pocket pacemaker; Comprise the buffer that double operational U3B (NE5532) constitutes, the ultra-low frequency amplifier by T1, T2, R1-R5 constitute is amplified to the scope of 0-24V and enough current values to the stimulus signal of the 0-5V of U2 output, and delivers to output electrode.The first order is made of T1, R1-R4, and input signal is by the input of the emitter stage of T1, and amplifying signal directly outputs to the base stage of second level amplifier T2 by colelctor electrode, and electric current is amplified the emitter stage output of back by T2, delivers to electrode wires as gastrointestinal physiology pacing signal; Buffer comprises amplifier U3B, connects the output of filter circuit C3, links to each other with output 1 foot of U3A, and it is exported 7 feet and links to each other the form of formation voltage follower with the emitter stage of T1 in the amplifier.Employing-24V power supply.
Fig. 4 is intelligent multiparameter external gastrointestinal physiology pacemaker " house dog " circuit theory diagrams of pocket; Comprise that " house dog " module U4 (MAX706) and two input nand gate integrated package U5D (74LS00), resistance R 6 and capacitor C 4 constitute, 8 feet of U4 link to each other with the P1.7 mouth of U1, and 7 feet link to each other with 12 feet of U5D, 6 feet link to each other with C4; The C4 other end links to each other with 13 feet of resistance R 6 one ends, U5D; Output 11 feet of U5D link to each other with reset terminal the 9th foot of U1, as electrification reset and program operation monitoring.
System is resetted and during because of extraneous strong jamming " race flies ", microcontroller U1 is resetted, enter normal operating conditions in program.
Fig. 5 is the power module figure of the external gastrointestinal physiology of the intelligent multiparameter of pocket pacemaker.Provide+the 5V power supply to microcontroller circuit, for D/A converting circuit provide+5V ,-the 5V power supply, for amplifying circuit provides-the 24V power supply.Power module input can or exchange voltage after DC converting and voltage stabilizing for cell voltage.
Operation principle: through keyboard circuit input stimulus signal waveform kind, parameter, according to the keypad information match, synthetic corresponding digital waveform is delivered to D/A converting circuit and is produced analog waveform by microcontroller; Microcontroller send keypad information the display part to show simultaneously, forms man machine interface, is convenient to regulate and function selecting.The D/A converting circuit output signal is amplified through ultra-low frequency amplifier, outputs to electrode as pacing signal.Output signal is the class sinusoidal signal of per minute 2-20 time, and at its flat-top phase or the descending branch different series of pulses signal (quantity, frequency, amplitude are all adjustable) of two-stage dutycycle that superposeed.
Claims (7)
1, the external gastrointestinal physiology of the intelligent multiparameter of pocket pacemaker, it is characterized in that by microcontroller circuit, D/A converting circuit, filter circuit, signal damping and amplifying circuit of analog signal, display circuit, keyboard circuit, " house dog " circuit, power circuit, and the electrode wires of output and the medical body surface of intrasonic stick electrode slice and portable enclosure and form; Wherein the P2 mouth of the microprocessor U1 of microcontroller directly is connected with the digital to analog converter data input pin; The analogue signal of D/A converting circuit output links to each other with filter circuit; Filter circuit links to each other with amplifying circuit of analog signal with signal damping, and amplifying signal is input to the medical body surface of intrasonic at last and sticks on the electrode slice; The P0 mouth of microprocessor U1 links to each other with J1 as LCD MODULE data presented transmission mouth, and J1 is connected to display module; Keyboard circuit links to each other with the P1 mouth of microprocessor U1; The output of " house dog " circuit links to each other with reset terminal 9 feet of microcontroller U1.
2, the external gastrointestinal physiology of the intelligent multiparameter of pocket according to claim 1 pacemaker is characterized in that the clock oscillation circuit that microcontroller is made up of microprocessor U1 and C1, C2,12M crystal oscillator constitutes; Wherein the P2 mouth of U1 (89C51) directly is connected with digital to analog converter, the P0 mouth links to each other with J1 as LCD MODULE data presented transmission mouth, J1 is connected to display module, keyboard circuit links to each other with the P1 mouth of U1, the oscillating circuit that C1, C2,12M crystal oscillator constitute is connected with 18,19 feet of U1, produces the required clock signal of U1.
3, the external gastrointestinal physiology of the intelligent multiparameter of pocket according to claim 1 pacemaker is characterized in that D/A converting circuit comprises digital to analog converter U2 and amplifier U3A; The data input pin of digital to analog converter U2 directly is connected with the P2 mouth of U1, and the CS of U2, WR1, WR2, Xfer hold direct ground connection; Signal after the U2 conversion outputs to 2,3 inputs of amplifier U3A from 11,12 ends, and 9 feet of U2 link to each other with output 1 foot of amplifier U3A, constitute the D/A converting circuit that leads directly to; The analogue signal of output is delivered to filter circuit C3.
4, the external gastrointestinal physiology of the intelligent multiparameter of pocket according to claim 1 pacemaker, it is characterized in that buffering and amplifying circuit comprise amplifier U3B, T1, T2, the two-stage amplifying circuit that resistance R 1-R5 forms, the first order is made of T1, R1-R4, input signal is by the emitter stage input of T1, amplifying signal directly outputs to the base stage of second level amplifier T2 by colelctor electrode, and electric current is amplified the emitter stage output of back by T2, delivers to electrode wires as gastrointestinal physiology pacing signal; Buffer comprises amplifier U3B, connects the output of filter circuit C3, links to each other with output 1 foot of U3A, and it is exported 7 feet and links to each other the form of formation voltage follower with the emitter stage of T1 in the amplifier.
5, the external gastrointestinal physiology of the intelligent multiparameter of pocket according to claim 1 pacemaker is characterized in that " house dog " circuit is made of U4, C4, R6 and U5D; 8 feet of U4 link to each other with the P1.7 mouth of U1, and 7 feet link to each other with 12 feet of U5D, 6 feet link to each other with C4; The C4 other end links to each other with 13 feet of resistance R 6 one ends, U5D; Output 11 feet of U5D link to each other with reset terminal the 9th foot of U1, as electrification reset and program operation monitoring.
6, the external gastrointestinal physiology of the intelligent multiparameter of pocket according to claim 1 pacemaker is characterized in that display circuit is made of the interface J1, the J2 that are connected with control circuit and Modular L CD circuit; The display circuit data are directly exported by the data output P0 mouth of U1.
7, the external gastrointestinal physiology of the intelligent multiparameter of pocket according to claim 1 pacemaker is characterized in that power circuit adopts the integrated power supply module.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02222253 CN2537413Y (en) | 2002-04-15 | 2002-04-15 | Pocket intelligent multiple parameter external gastro intestine phisiologic pacemaker |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02222253 CN2537413Y (en) | 2002-04-15 | 2002-04-15 | Pocket intelligent multiple parameter external gastro intestine phisiologic pacemaker |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2537413Y true CN2537413Y (en) | 2003-02-26 |
Family
ID=33700208
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02222253 Expired - Fee Related CN2537413Y (en) | 2002-04-15 | 2002-04-15 | Pocket intelligent multiple parameter external gastro intestine phisiologic pacemaker |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2537413Y (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1947812B (en) * | 2006-11-03 | 2010-04-21 | 杨涛 | Gastrointestinal pacemaker |
| CN105617530A (en) * | 2016-03-02 | 2016-06-01 | 西安交通大学第一附属医院 | Digital gastrointestinal pacemaker |
-
2002
- 2002-04-15 CN CN 02222253 patent/CN2537413Y/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1947812B (en) * | 2006-11-03 | 2010-04-21 | 杨涛 | Gastrointestinal pacemaker |
| CN105617530A (en) * | 2016-03-02 | 2016-06-01 | 西安交通大学第一附属医院 | Digital gastrointestinal pacemaker |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Salem et al. | Electrical stimulation at a frequency higher than basal rate in human stomach | |
| Familoni et al. | Efficacy of electrical stimulation at frequencies higher than basal rate in canine stomach | |
| AU2017202237B2 (en) | Non invasive neuromodulation device for enabling recovery of motor, sensory, autonomic, sexual, vasomotor and cognitive function | |
| US8630716B2 (en) | Systems and methods for providing neural stimulation transitions | |
| US8630709B2 (en) | Computer-implemented system and method for selecting therapy profiles of electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction | |
| CN102143780B (en) | Systems for delivering vagal nerve stimulation | |
| Qian et al. | Normalization of atropine-induced postprandial dysrhythmias with gastric pacing | |
| US8135470B2 (en) | Energy balance therapy for obesity management | |
| US7787948B2 (en) | Energy efficient therapeutic pulse generator system | |
| WO2007130177A1 (en) | Activity level feedback for managing obesity | |
| EP2401029A1 (en) | Closed-loop neurostimulation to treat pulmonary edema | |
| Gai et al. | Advances in health rehabilitation devices based on triboelectric nanogenerators | |
| Kim et al. | Electrical stimulation for therapeutic approach | |
| Wang et al. | Novel implantable devices delivering electrical cues for tissue regeneration and functional restoration | |
| CN2537413Y (en) | Pocket intelligent multiple parameter external gastro intestine phisiologic pacemaker | |
| CN208302083U (en) | A kind of pelvic diaphragm muscle instrument for training | |
| Lee et al. | Direct stimulation of bladder pelvic nerve using battery-free neural clip interface | |
| CN106039562B (en) | Electronic anti-emesis instrument and control method | |
| CN202538167U (en) | Chronic cough therapeutic instrument | |
| CN1048183C (en) | Portable gastrointestinal electric artificial pacemaker | |
| CN2531818Y (en) | Weidongshu therapeutic apparatus | |
| CN1305777A (en) | Stomach power test method and tester based on said method | |
| CN218010640U (en) | Closed loop percutaneous acupoint electrical stimulation equipment | |
| CN218106583U (en) | Transcutaneous electrical nerve stimulation device synchronized with gastrointestinal electricity | |
| Gopu et al. | Electrogastrogram recovery for correction of gastric disorders using gastric stimulator |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |