CN1048183C - Portable gastrointestinal electric artificial pacemaker - Google Patents

Portable gastrointestinal electric artificial pacemaker Download PDF

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Publication number
CN1048183C
CN1048183C CN 95118078 CN95118078A CN1048183C CN 1048183 C CN1048183 C CN 1048183C CN 95118078 CN95118078 CN 95118078 CN 95118078 A CN95118078 A CN 95118078A CN 1048183 C CN1048183 C CN 1048183C
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China
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circuit
programmable device
online programmable
agitator
output
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CN 95118078
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CN1128673A (en
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欧阳守
章锦芝
侯淑兰
吴翠明
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Abstract

The present invention relates to an electrotherapeutic device for electrically stimulating stomach intestines, which comprises an on-line programmable apparatus, a frequency display circuit, a weighted resistance network, a simulation amplification circuit, an output electrode and a power source, wherein the on-line programmable apparatus is connected with the weighted resistance network and the frequency display circuit, the output of the weighted resistance network is output to a body surface application electrode by the simulation amplification circuit, and a battery is used by the power source. In addition, the electrotherapeutic device is provided with a frequency regulation circuit, an amplitude regulation circuit and an amplitude display circuit. The bioelectric information simulating the enterocinetic rule of the stomach intestine of a normal person is fed back to the pacemaker of the stomach intestine of a patient to enable the enterocinetic rule of the stomach intestine of the patient to follow the enterocinetic rule of the stomach of a normal person; thus, various clinical symptoms of the stomach intestine are relieved or eliminated. The electrotherapeutic device has the advantage of miniaturization, and can be carried about by patients.

Description

Portable gastrointestinal electric artificial pacemaker
The present invention relates to the electrotherapeutic apparatus that a kind of gastrointestinal electricity irritation is used.
The myoelectrical activity of stomach can be traced from body surface, its figure claims clectrogastrogram (EGG), existing corresponding diagnosis and the therapeutic equipment checked, for example the Electrogastrograph meter of the multiple tracks of the stomach functional check instrument of the gastrointestinal disease intelligent diagnosing instrument of CN2076821U patent application, CN2069713U patent application, CN2051495U patent application intelligence gastrointestinal electrographic instrument, CN2077258U patent application etc. is checked diagnostic apparatus, the and for example therapeutic equipments such as gastritis direct current therapy unit of the gastric ulcer of CN2045268U patent application and gastrointestinal disease apparatus for diagnosis and therapy, CN2030486U patent application.
Dissect physiology and clinical trial according to animal, gastrointestinal smooth muscle has autorhythmicity, even under situation on an empty stomach, also can record spontaneous, slow, rhythmicity depolarization wave, be basic electrical rhythm (BER), also claim pacemaker current potential (PSP) or slow wave, and driving and following effect are arranged, the activity of control pacemaker, the may command gastrointestinal motility regularity.When stomach rule disorderly (GD), the frequency of clectrogastrogram, amplitude, the rhythm and pace of moving things change, and the stomach rule occurs and overrun, cross and relax uneven three kinds of situations, and BER is regulating and control time, frequency, position and the direction of gastrointestinal movement.The basic design that for this reason proposes gastrointestinal pacemaker is at gastrointestinal tract, as cardiac pacing, corrects gastrointestinal abnormal motion state.The bio-electrical information of simulation normal person gastrointestinal motility regularity is fed back to patient's gastrointestinal pacemaker, make patient's gastrointestinal motility regularity follow normal person's gastrointestinal peristalsis and be gastrointestinal pacemaker.
Purpose of the present invention aims to provide a kind of patient and can carry, and has the portable gastrointestinal electric artificial pacemaker of gastrointestinal pacemaker function.
The present invention includes online device able to programme, frequency display circuit, weighted resistance network, analog amplify circuit, output electrode and power supply.The input of the serial data of online programmable device, serial data output, mode are selected, serial clock and control signal five lines are the ISP DLL; The shift register output port of online programmable device connects the input of weighted resistance network, the input of the output termination analog amplify circuit of weighted resistance network, the output termination output electrode of analog amplify circuit; The decoder driver output termination frequency display circuit of online programmable device.Adopt battery power supply.
The online programmable device is made up of the online programmable device of bearing agitator, frequency divider, shift register, decade computer, latch, decoder driver and logic digital circuits and " the online programmable device first oscillator frequency regulating circuit ", " online programmable device second agitator ", " the online programmable device first oscillator frequency regulating circuit " connects " the external agitator of online programmable device " interface, and " online programmable device second agitator " connects " the external agitator of second agitator of online programmable device " interface.
Analog amplify circuit is made up of impedance matching circuit and proportional amplifier, the outfan of the input termination weighted resistance network of impedance matching circuit, the input of the output termination proportional amplifier of impedance matching circuit, the output termination output electrode of proportional amplifier.Analog amplify circuit can be established amplitude adjusting circuit and amplitude display circuit, and amplitude adjusting circuit connects proportional amplifier, the outfan of the input termination impedance matching circuit of amplitude display circuit.
Output electrode adopts medical body surface to stick electrode.
Power supply can adopt the battery step to rise transducer or general high capacity type dry cell or rechargeable battery.
The present invention feeds back to patient's gastrointestinal pacemaker according to the bio-electrical information of simulation normal person gastrointestinal motility regularity, makes patient's gastrointestinal motility regularity follow normal person's gastric peristalsis.As everyone knows, gastrointestinal disease is a kind of commonly encountered diseases, frequently-occurring disease.At present, some gastrointestinal disease can heal with medicine, and some functional gastrointestinal disease can't heal with medicine, and generally the electronics physiotherapy can solve, and some gastrointestinal disease patient requires the long-time treatment of following the tracks of.The present invention is to provide and to allow the patient carry, miniaturization, at any time give a kind of power of gastrointestinal peristalsis (electric field force), make abnormal wriggling rule recover normal gastrointestinal pacemaker, it can make various clinical symptoms (as gastric abscess, abdomen rise, dim gas, anorexia, stomach discomfort etc.) be eased or disappear, especially effective to gastroptosis, simultaneously bile reflux type gastritis, gastric volvulus, cardia achalasia also there are satisfied curative effect.
Fig. 1 is a structured flowchart of the present invention.
Fig. 2 is circuit theory diagrams of the present invention.
Fig. 3 rises the converter circuit schematic diagram for the battery step.
As shown in Figure 1, the present invention is made up of online programmable device (1), weighted resistance network (2), analog amplify circuit (3), output electrode (4), amplitude display circuit, frequency display circuit (5) and power supply etc.The shift register output port of online programmable device (1) connects the input of weighted resistance network (2), the input of the output termination analog amplify circuit (3) of weighted resistance network, the output termination output electrode (4) of analog amplify circuit, the decoder driver output termination frequency display circuit (5) of online programmable device.
As shown in Figure 2, the online programmable device is made up of online programmable device, " the online programmable device first oscillator frequency regulating circuit " and " online programmable device second agitator ", online programmable device device is born vibration, frequency division, shift LD, decimal scale and is counted, latchs, deciphers and drive and some other logic digital circuits, can be by IC 1(ISPLS 2064) finish A 0~A 4Be respectively serial data input (SD), the serial data output (SD of online programmable device 0), mode selects (MODE), serial clock (SLCK) and control signal SLOCK (ISPEN) five lines (ISP programming) interface, port is I/O 70~74.Obviously, all functions of above circuit can realize by Programming Design, for example adopt Lai Dixi software PDS, and by following 4 the step form.
1) typing design: foregoing circuit (TTL and MOS) function Boolean equation or macro-instruction are write out, use the plug-in type text editor, each unit in Boolean equation or the macro-instruction typing ISPLSI 2064 device squares.
2) verification design: be overall verification after typing is finished in all designs, this verification is to seek input whether to be connected to path module, looks at whether network repeats title.
3) path design: after verification was all passed through, binding program in path linked total logic module, so that input of I/O unit and unit output.
4) overall line graph: this is to obtain verification design, path design, and sets up and need the part of programming behind the JEKEC (the line file of a normal binary).
" the external frequency adjustment circuit of online programmable device first agitator " is by R 1, R 2, C 1, W 1Form W 1Be frequency adjustment potentiometer, C 1A termination IC 1I/O 54 ports, R 1A termination 53 ports, R 2A termination 55 ports." online programmable device second agitator " is by R 3, C 2, C 3, (1.8~2MHz) form crystal JD, C 2, C 3Connection termination IC 1I/O 50 ports, the two ends of crystal JD respectively with IC 151,52 ports connect.Above-mentioned oscillator signal needs frequency division, displacement, by IC 1I/O 30~37 ports meet weighted resistance network R respectively 4~R 11, finish frequency transformation, also send simultaneously behind decade computer, latch, the decoder driver by IC 1I/O 1~22 port connect frequency display circuit (OCM-8).The circuit structure of said weighted resistance network is power resistance parallel circuit as shown in Figure 2, its input termination shift register output port, and the input of output termination impedance matching circuit.
Analog amplify circuit adopts two amplifier IC 2(LM358), preceding 1/2 LM358 is connected into the emitter follower form as impedance matching circuit, its input (IC 2The 2nd foot) connect the outfan of weighted resistance network; Back 1/2 LM358 is a proportional amplifier, class sinusoidal variations track is provided for gastrointestinal portion, and amplitude generally is not more than the electric field force of 1mA, the outfan of the input termination impedance matching circuit of proportional amplifier, the outfan (IC of proportional amplifier 2The 7th foot) connect medical body surface and stick disk electrode, insert amplitude adjusting circuit between the input of proportional amplifier, the outfan, by adjustable potentiometer W 2Finish.
Outfan (the IC of impedance matching circuit 2The 1st foot) connect the amplitude display circuit, amplitude shows by IC 3Serve as (SF 3914), 10 light emitting diodes successively brightness for from low to high, the power of expression treatment amplitude.Its negative pole is connected to IC respectively 3The the 1st and the 10th~18 foot, and positive pole all is connected.
Power supply can adopt general battery (aneroid battery or rechargeable battery) or battery step to rise transducer, as shown in Figure 3, and by IC 4(MAX757 or MAX761) and auxiliary circuit (C 4, C 5, C 6, L, D 11Deng) form.
This shows, gastrointestinal pacemaker constitutes series loop with gastrointestinal with it as a load resistance, in fact passing gastrointestinal is that a per minute changes 3~20 times, and be superimposed with the current locus of 10~30HZ at the trailing edge of this variation, so put on the electric field force of gastrointestinal portion, this electric field force forces gastrointestinal portion to follow its Changing Pattern and changes.

Claims (3)

1. portable gastrointestinal electric artificial pacemaker, it is characterized in that 1) online programmable device of row, the input of its serial data, serial data output, mode are selected, serial clock and control signal five lines are the ISP DLL, the shift register output port of online programmable device connects the input of weighted resistance network, the input of the output termination analog amplify circuit of weighted resistance network, the output termination output electrode of analog amplify circuit, the decoder driver output termination frequency display circuit of online programmable device, power supply source adopts battery; 2) said online programmable device is made up of the online programmable device of bearing agitator, frequency divider, shift register, decade computer, latch, decoder driver and logic digital circuits and " the online programmable device first oscillator frequency regulating circuit ", " online programmable device second agitator ", " the online programmable device first oscillator frequency regulating circuit " connects " the external agitator of online programmable device " interface, and " online programmable device second agitator " connects " the external agitator of second agitator of online programmable device " interface; 3) said weighted resistance network is power resistance parallel circuit; 4) said analog amplify circuit is made up of impedance matching circuit and proportional amplifier, the outfan of the input termination weighted resistance network of impedance matching circuit, the input of the output termination proportional amplifier of impedance matching circuit, the output termination output electrode of proportional amplifier.
2. portable gastrointestinal electric artificial pacemaker as claimed in claim 1, it is characterized in that the online programmable device adopts ISPLSI2064, serial data input, serial data output, mode are selected, serial clock and control signal port are I/O 70~74, the frequency display circuit connectivity port is I/O 1~22, the connectivity port of the frequency adjustment circuit of online programmable device first agitator is I/O 53~55, the connectivity port of online programmable device second agitator is I/O 50~52, crystal frequency is 1.8~2MHz, and the connectivity port of weighted resistance network is I/O 30~37.
3. portable gastrointestinal electric artificial pacemaker as claimed in claim 1, it is characterized in that analog amplify circuit establishes amplitude adjusting circuit and amplitude display circuit, amplitude adjusting circuit connects proportional amplifier, and the outfan of the input termination impedance matching circuit of amplitude display circuit.
CN 95118078 1995-10-30 1995-10-30 Portable gastrointestinal electric artificial pacemaker Expired - Fee Related CN1048183C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 95118078 CN1048183C (en) 1995-10-30 1995-10-30 Portable gastrointestinal electric artificial pacemaker

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 95118078 CN1048183C (en) 1995-10-30 1995-10-30 Portable gastrointestinal electric artificial pacemaker

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CN1128673A CN1128673A (en) 1996-08-14
CN1048183C true CN1048183C (en) 2000-01-12

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CN 95118078 Expired - Fee Related CN1048183C (en) 1995-10-30 1995-10-30 Portable gastrointestinal electric artificial pacemaker

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6216039B1 (en) * 1997-05-02 2001-04-10 Medtronic Inc. Method and apparatus for treating irregular gastric rhythms
EP1641522B1 (en) * 2003-06-20 2012-12-19 Metacure Limited Gastrointestinal apparatus for detecting a change in posture

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