CN2441811Y - Hybrid instrument - Google Patents
Hybrid instrument Download PDFInfo
- Publication number
- CN2441811Y CN2441811Y CN 00246913 CN00246913U CN2441811Y CN 2441811 Y CN2441811 Y CN 2441811Y CN 00246913 CN00246913 CN 00246913 CN 00246913 U CN00246913 U CN 00246913U CN 2441811 Y CN2441811 Y CN 2441811Y
- Authority
- CN
- China
- Prior art keywords
- hybridization
- peristaltic pump
- utility
- plate
- liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Landscapes
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The utility model relates to a hybrid instrument. A reagent box, an electromagnetic valve, a peristaltic pump, a hybrid plate, a temperature control case and a waste liquid box are arranged in a casing of the utility model. The reagent box is in a funnel shape. The reagent box is connected with the electromagnetic valve. A main passage of each liquid inlet pipe is connected with one end of the peristaltic pump. The other end of the peristaltic pump is connected with the hybrid plate. The hybrid plate is arranged in the temperature control case. The utility model makes a bybrid process standard and programmed by temperature adjustment and the control of a liquid inlet amount and liquid inlet speed. The utility model makes hybrid time shortened and makes a result accurate.
Description
The utility model belongs to full nucleic acid hybridization instrument, is mainly used in specific detection nucleic acid, is applicable to the various occasions that need carry out nucleic acid hybridization.
At present, nucleic acid hybridization is mainly finished by manual, and each step all needs manually to change reagent, attemperation, and some step also needs the vibration that do not stop; Even the hybrid heater that uses needs the staff when the linking in each step at present, change reaction reagent by hand, set next step working conditions, comprise time, temperature etc., entire reaction course needs 2～3 days, takes time and effort.
The purpose of this utility model is to overcome the weak point that prior art exists, a kind of hybridization instrument is provided, continue to flow by controlled liq, realize the operating process automatization, improve hybridization efficiency, both shortened about crossover process to 10 hour, reach and save labour and time, make crossover process stdn, standardization again, the result is accurate.
The utility model is achieved through the following technical solutions: be provided with test kit, magnetic valve, peristaltic pump, hybridization plate, temperature control box, waste liquid box in the housing of hybridization instrument, test kit is funnel-form, liquid adding hole is arranged on the top cover, the lower end links to each other with an end of liquid-inlet pipe, the other end of liquid-inlet pipe links to each other with magnetic valve, and the overall channel of liquid-inlet pipe is connected with an end of peristaltic pump, and the peristaltic pump the other end links to each other with the hybridization plate, the other end of hybridization plate is connected with the waste liquid box, and the hybridization plate is arranged in temperature control box.
Have a square pan in the middle of the hybridization plate of the present utility model, have a symmetric channel in the pan.
The utlity model has following characteristics: 1, reasonable in design, easy to operate, the result is accurate; 2, operating process is not subjected to the influence of outside air temperature, has greatly improved the efficient and the quality of hybridization; 3, shortened hybridization time (foreshortening to about 10 hours), the staff is freed from loaded down with trivial details experiment, both saved labour and time, made crossover process stdn, standardization again from common 2～3 days.
Description of drawings of the present utility model is as follows:
Fig. 1 is the utility model structural representation.
Fig. 2 is the synoptic diagram of hybridization plate.
The utility model will be further described in conjunction with the accompanying drawings.
Referring to Fig. 1, Fig. 2, hybridization instrument mainly is provided with test kit 2 in housing 1, magnetic valve 3, peristaltic pump 4, hybridization plate 5, temperature control box 6, waste liquid box 7, test kit 2 is funnel-form, there is liquid adding hole 8 on the top, the lower end links to each other with an end of liquid-inlet pipe 9, the other end of liquid-inlet pipe 9 links to each other with magnetic valve 3, the overall channel 10 of liquid-inlet pipe 9 is connected with an end of peristaltic pump 4, peristaltic pump 4 the other ends link to each other with hybridization plate 5, the other end of hybridization plate 5 is connected with waste liquid box 7, and hybridization plate 5 is arranged in temperature control box 6, and has a pan 11 in the middle of hybridization plate 5, can place acetate film to be acted on, have a symmetric channel 12 in the pan 11.
Workflow of the present utility model is: in order reagent is added the test kit 2 of numbering in advance from liquid adding hole 8 earlier, set the temperature of temperature control box 6 then, regulating and controlling temperature is between 0 ℃～100 ℃, precision ± 0.1 ℃, the hybridization plate 5 that is placed with acetate film to be acted on is put into temperature control box 6, after reaching preset temperature, promptly start the magnetic valve 3 of first test kit 2 correspondence, input reagent, in advance according to reagent requirement, set the speed of peristaltic pump 4, rotating speed is from 0.1～100 rev/min, control reagent flows into the time of peristaltic pump 4 through overall channel 10 from magnetic valve 3, the pan 11 that the end of reagent by peristaltic pump 4 flows into the hybridization plate 5 that is arranged in temperature control box 6 carries out hybridization, and by hybridizing the symmetric channel 12 of plate 5, make the reagent after the effect flow into waste liquid box 7, finish a kind of application of sample of reagent, after the reagent of first test kit 2 adds, close first magnetic valve 3, open second magnetic valve 3, import second kind of reagent, repeat above-mentioned steps, and the like, promptly finished whole crossover process.Thin bore (1-2mm) pipeline is all adopted in the connection of each fluid path.
This operation steps all adopts computer program control, sets in advance dosage, infusion time length and the order of each magnetic valve reagent, and the running speed of peristaltic pump is set, and whole crossover process was both saved time, and is accurate again.
Claims (2)
1. hybridization instrument, it is characterized in that: be provided with test kit (2) in the housing of hybridization instrument (1), magnetic valve (3), peristaltic pump (4), hybridization plate (5), temperature control box (6), waste liquid box (7), test kit (2) is funnel-form, liquid adding hole (8) is arranged on the top cover, the lower end links to each other with an end of liquid-inlet pipe (9), the other end of liquid-inlet pipe (9) links to each other with magnetic valve (3), the overall channel (10) of liquid-inlet pipe (9) is connected with an end of peristaltic pump (4), the other end of peristaltic pump (4) links to each other with hybridization plate (5), the other end of hybridization plate (5) is connected with waste liquid box (7), and hybridization plate (5) is arranged in temperature control box (6).
2. hybridization instrument as claimed in claim 1 is characterized in that: have a pan (11) in the middle of the hybridization plate (5), have a symmetric channel (12) in the pan (11).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00246913 CN2441811Y (en) | 2000-08-03 | 2000-08-03 | Hybrid instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00246913 CN2441811Y (en) | 2000-08-03 | 2000-08-03 | Hybrid instrument |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2441811Y true CN2441811Y (en) | 2001-08-08 |
Family
ID=33606039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 00246913 Expired - Fee Related CN2441811Y (en) | 2000-08-03 | 2000-08-03 | Hybrid instrument |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2441811Y (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101942385B (en) * | 2009-07-06 | 2013-08-14 | 中山大学达安基因股份有限公司 | Full-automatic hybridization oven and implementation method and application thereof |
| CN105115949A (en) * | 2005-12-21 | 2015-12-02 | 梅索斯卡莱科技公司 | Assay apparatuses, methods and reagents |
| US11300571B2 (en) | 2005-12-21 | 2022-04-12 | Meso Scale Technologies, Llc. | Assay apparatuses, methods and reagents |
-
2000
- 2000-08-03 CN CN 00246913 patent/CN2441811Y/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105115949A (en) * | 2005-12-21 | 2015-12-02 | 梅索斯卡莱科技公司 | Assay apparatuses, methods and reagents |
| CN105115949B (en) * | 2005-12-21 | 2018-06-22 | 梅索斯卡莱科技公司 | Analytical equipment, method and reagent |
| US11300571B2 (en) | 2005-12-21 | 2022-04-12 | Meso Scale Technologies, Llc. | Assay apparatuses, methods and reagents |
| US11892455B2 (en) | 2005-12-21 | 2024-02-06 | Meso Scale Technologies, Llc. | Assay apparatuses, methods and reagents |
| CN101942385B (en) * | 2009-07-06 | 2013-08-14 | 中山大学达安基因股份有限公司 | Full-automatic hybridization oven and implementation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN2441811Y (en) | Hybrid instrument | |
| CN2466390Y (en) | Industrial process flow intelligent pump | |
| CN209800272U (en) | Backflow adjusting device suitable for liquid ring pump of thermal power plant | |
| CN206556731U (en) | Gas flowmeter calibration system | |
| CN2640213Y (en) | Full automatic integrated machine for irrigating, fertilizing and filtering | |
| CN2548138Y (en) | IC engine characteristic low-pressure analogical test table | |
| CN102562259A (en) | Air inlet temperature control system of engine | |
| CN2444230Y (en) | Immunohistochemistry apparatus | |
| CN202597133U (en) | High-speed low-flow centrifugal compressor unit | |
| CN204811360U (en) | Indoor green control system that plants of intelligence | |
| CN208139613U (en) | Accurate temperature controlling refrigeration system | |
| CN209143709U (en) | A kind of quartz sand acid washout iron exclusion device | |
| CN207297497U (en) | Numerical control bender drives oil pump device | |
| CN209926671U (en) | Intelligent water collection control system of electrochemical water treatment device | |
| CN202304510U (en) | Plate heat exchanger system in emulsified asphalt production line | |
| CN202147068U (en) | Cutting fluid circulating system | |
| CN206191564U (en) | Condensed water recovery device | |
| CN205227600U (en) | Complete ad hoc fan air conditioning unit of heat recovery | |
| CN205528952U (en) | Quick oxidation fe2+'s removal bed bioreactor | |
| CN1028454C (en) | Numerically controlled high-flow regulating valve | |
| CN209355557U (en) | Drenching installation is used in a kind of cooling of Ventilator Room | |
| CN215992260U (en) | Membrane method water-fertilizer drip irrigation device for guaranteeing soilless planting | |
| CN209927440U (en) | Throttling device testing device | |
| CN202759942U (en) | Special device for low water pressure electro-magnetic water driven irrigation device | |
| CN220696541U (en) | Water tank stirring system of water efficiency performance test board |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |