CN2345224Y - Therapeutic catheter used in esophageal cavity - Google Patents

Abstract

The utility model relates to an esophageal lumen treating conduit used for oesophagus cancer chemotherapy or immunotherapy, comprising a main conduit (10) which is suitable for being inserted in an oesophagus from a nasal cavity. The inner part of the main conduit is provided with four independent through cavities which are mutually isolated and are independently communicated with a front air bag (17), a back air bag (12), a saliva sucking hole (11), a medicine liquid sucking hole (14) and a medicine liquid dropping hole (15). The tail ends of the through cavities are respectively drawn four branch pipes (1), (4), (5) and (8) which are used for inflating operation, suction operation and dosage operation. The utility model can block the cancer pathologic change segment of an esophageal lumen and cause anticancer medicine to be directly act on pathologic change tissue, and the utility model can use most effective medicine concentration acting on canceration positions and reduce medicine side effects to minimum limit.

Description

Esophageal lumen internal therapy conduit

This utility model relates to a kind of medical apparatus and instruments, promptly a kind of can be in esophageal lumen local directly apparatus of administration.

The effective method of current treatment for the esophageal carcinoma is the excision pathological tissues, still, for the bigger case of extent of disease, and in order to improve the long-term survival rate of esophageal carcinoma patients after surgery, prevents from recurrence from preferably can give suitable chemotherapy before operation.

Yet the systemic chemotherapy of the esophageal carcinoma is owing to supplied and oncology's characteristic limitations by esophagus blood, and the valid density that medicine arrives tumor is very low, is difficult to performance and significantly presses down the cancer effect.Employing is handled the esophageal carcinoma through the tremulous pulse interventional therapy and is also extensively carried out because of esophagus blood deposition undesirable being difficult to of condition.

This utility model aims to provide a kind of device that can carry out direct topical to the cancerous issue in the esophageal lumen, so as to improving the chemotherapy effect of the esophageal carcinoma, reduces side effect.Its principle mainly is conceived to more like this, be that the change of esophagus carninomatosis is the epithelial canceration of mucous membrane of esophagus, then along esophageal wall to around soak into and diffusion, so the esophageal carcinoma has the bigger surface that directly contacts with medicine, and most of esophageal carcinoma surface formed ulcer, this also for drug absorption be impregnated into the tumor deep layer advantage be provided.

This utility model is achieved in that it comprises that one is suitable for inserting the main pipe that the macromolecular material of esophagus is made by nasal cavity, it is characterized in that: this main pipe is four cavities conduit pipes, four mutual isolated independent cavities are promptly arranged in the pipe, comprise absorbing cavity, medicinal liquid splashes into the chamber, preceding balloon inflation lumen and rear gasbag inflatable chamber, the front end of main pipe is the blunt conical head of real core of sealing, two air bags of being close to the main pipe outer wall are arranged at the rear of this conical head, be the preceding air bag of nearly stomach end and the rear gasbag of near mouthful of end, the trailing edge of pro-air bag and the leading edge of rear gasbag respectively have a radiopaque labelling, medicine liquid droplet portal [15] is arranged on the main pipe outer wall at pro-labelling rear, on the main pipe outer wall in labelling the place ahead, back, there is medicinal liquid to attract the hole, on the main pipe outer wall at rear gasbag rear, there is saliva to attract the hole, medicine liquid droplet portals and splashes into the chamber with medicinal liquid and be connected, medicinal liquid attracts hole and saliva to attract the hole to be connected with attracting the chamber, preceding balloon inflation lumen and rear gasbag inflatable chamber are connected with preceding air bag and rear gasbag respectively, for ease of operation, the tail end of four cavities extends four arms respectively in main pipe, promptly attract the chamber to be connected with suction manifold, medicinal liquid splashes into the chamber and splashes into arm with medicinal liquid and be connected, preceding airbag aeration arm is connected with preceding air bag, and rear gasbag inflation arm is connected with rear gasbag.

Adopt this utility model, the doctor can guide diarrhea with above-mentioned front and back labelling in X line perspective, the appropriate location of treatment conduit insertion patient esophagus, and by the front and back airbag aeration is made airbag inflation, block to live the esophagus tube chamber at esophageal neoplasm two ends, at this moment, can inhale the saliva that flows into esophageal lumen at any time through attracting the chamber by suction manifold on the one hand, simultaneously can splash into arm by medicinal liquid and splash into chamber and medicine liquid droplet through medicinal liquid and portal medicine (chemotherapeutics or immunotherapy medicaments) continuous drip in tumor locus, the liquid behind the performance drug effect can be through attracting the hole and attracting the chamber go from suction manifold suction in time.

For keeping the inflation state during medicinal liquid instils treatment, air bag before and after making plays the effect of stopping up esophageal lumen, the tail end of pro-, rear gasbag inflation arm is provided with surveys capsule and check valve, check valve is used to guarantee charging into and pressurize of air, survey capsule and be used to indicate whole loading line to comprise that air bag itself does not have not leakage, can keep the inflation state because under no leak condition, survey capsule.

After conduit inserts the esophagus appropriate location slide displacement taking place for preventing to treat, be provided with on main pipe and can move forward and backward along main pipe, and can be positioned bridge of the nose fixed mount on the main pipe outer wall.In addition, for guaranteeing that suction manifold, medicinal liquid splash into arm, preceding airbag aeration arm and rear gasbag inflation arm and be connected with the reliable of each corresponding independent cavity tail end in the main pipe, strengthen these junction points with a bunch block in addition, and these arms are fixed in the rear end of main pipe.Be specially adapted to mainly be arranged in the tumor of esophagus hypomere in view of this treatment conduit, length generally is no more than the patient of 60mm, therefore the spacing of two labellings is preferably 100～150mm before and after on the main pipe, after expanding with airbag aeration before and after guaranteeing, has enough medicinal liquids to station the space.

Make infusion therapy for ease of the doctor, the esophageal lumen internal therapy conduit of this utility model should be made with macromolecular material, and particularly silastic material or polyurethane material are made preferably for physiological compatibility and chemical stability.

By as seen above-mentioned, the esophageal lumen internal therapy conduit of employing this utility model can block the esophageal lumen at esophagus pathological changes section two ends, medicine can splash into the chamber continuous drip in tumor locus through the medicinal liquid of conduit, make it to directly act on the esophageal neoplasm surface, medicinal liquid after playing a role can attract chamber suction in time to go through conduit, make medicine can continue to act on tumor locus more than 4～6 hours, give full play to the therapeutical effect of chemotherapeutics and immune drug.Because the most effective and concentration of toxic and side effects minimum of continuous drip liquid Chinese medicine dosage scalable, thereby can bring into play the maximum hospital benefit of medicine, and the toxic and side effects of medicine is reduced to Min., also can not damage normal mucous membrane of esophagus.In addition, owing to the medicine after the treatment can be removed in whole transcatheter attraction chamber sucking-offs, thereby got rid of the side effect of medicine through gastrointestinal absorption.Therefore, will improve esophageal carcinoma patient's postoperative long-term survival rate greatly with the method before the esophageal carcinoma operation, also the non-operative treatment for the esophageal carcinoma provides new effective ways.

Zhongshan affiliated hospital of shanghai medical university once carried out chemotherapeutics instillation treatment to tens of routine patient with esophageal carcinoma with this utility model, clinical in CT and the contrast of perioperatively pathology, show that most tumors has tumor body in various degree to dwindle through chemotherapy in the esophageal lumen before the art, infiltration degree lightens.Under the mirror visible non-viable non-apoptotic cell than medication before showed increased, tumor cell pyknosis and karyorhexis also increase.Illustrate and adopt this utility model to carry out continuous drip chemotherapy and immune drug treatment in the esophageal lumen, effective, toxic and side effects is light.

The utility model is described in further detail with embodiment below in conjunction with accompanying drawing.

Fig. 1 is a structural representation of the present utility model, and Fig. 2 is the profile of A-A ' part among Fig. 1, and Fig. 3 is the sketch map of instillation medicinal liquid treatment after this utility model insertion esophageal lumen occluded lesions section, and wherein arrow is medicine or saliva flow directions.

Number in the figure is: airbag aeration arm before the 1-; 2,7-surveys capsule; 3,6-check valve; The 4-suction manifold; The 5-medicinal liquid splashes into arm; 8-rear gasbag inflation arm; The 9-bunch block; The 10-main pipe; 11-saliva attracts the hole; The 12-rear gasbag; 13, the radiopaque labelling of 16-; The 14-medicinal liquid attracts the hole; The 15-medicine liquid droplet portals; Air bag before the 17-; The blunt conical head of 18-; 19-bridge of the nose fixed mount; 20-attracts the chamber; Balloon inflation lumen before the 21-; The 22-medicinal liquid splashes into the chamber; 23-rear gasbag inflatable chamber.

Embodiment 1:

Referring to Fig. 1 and Fig. 2, with the silastic material that meets the medical sanitary requirement, four main pipes [10] of isolating cavities are mutually arranged in making with extrusion moulding, isolate cavity for attracting chamber [20] for these four, preceding balloon inflation lumen [21], medicinal liquid splashes into chamber [22], rear gasbag inflatable chamber [23], main pipe [10] is about 600mm, external diameter 6mm, the main pipe front end is processed into blunt conical head [18], with this conical head top on the main pipe at 40mm place and 200mm place, respectively with two inflated rubber capsules made from infusion process of bonding construction from part installation, promptly preceding air bag [17] and rear gasbag [12], main pipe outer wall in the capsule is provided with aperture, is connected with preceding balloon inflation lumen [21] and rear gasbag inflatable chamber [23] in the main pipe respectively.This two air bag is close to the outer wall of main pipe [10] before unaerated is expanded, the inflation back is inflatable to the φ 25mm.The leading edge of the trailing edge of pro-air bag [17] and rear gasbag [12] is coated with the organosilicon coating that any includes the opacity material respectively, become labelling [16] and [13], both are at a distance of about 120mm, on the main pipe outer wall at labelling [16] rear, have some and main pipe [10] inner liquid medicine and splash into medicine liquid droplet that chamber [22] is connected portal [15], on the main pipe outer wall in labelling [13] the place ahead, have some medicinal liquids that are connected with attraction chamber [20] in the main pipe [10] and attract hole [14], on the main pipe outer wall at rear gasbag [12] rear, have some salivas that are connected with attraction chamber [20] in the main pipe [10] and attract hole [11], four cavities in the main pipe [10], promptly attract chamber [20], preceding balloon inflation lumen [21], medicinal liquid splashes into chamber [22], the tail end of rear gasbag inflatable chamber [23] is connected with four silicone rubber tubes by the bonding construction from part respectively, these four silicone rubber tubes are followed successively by suction manifold [4], preceding airbag aeration arm [1], medicinal liquid splashes into arm [5] and rear gasbag inflation arm [8], airbag aeration arm [1] and [8] is about 100mm wherein, suction manifold [4] and medicinal liquid splash into arm [5] and are about 400mm, for preventing that these arm distortions from coming off, be convenient to inflate operations such as administration and attraction, these arms are inlaid in the bunch block of being made by real core silicon rubber piece [9] and are fixed in the tail end of main pipe [10].The tail end of pro-airbag aeration arm [1] and rear gasbag inflation arm [8] bonds respectively and assembles detection capsule [2] and [7] of being made by plastic membrane of polyvinyl chloride, at the afterbody of surveying capsule [2] and [7] check valve [3] and [6] are housed, like this, to front and back airbag aeration arms [1] and [8] inflation the time, because the effect of check valve [3] and [6], gas can not backflow, and survey capsule [2] and [7] understand along with preceding air bag [17] and rear gasbag [12] together by inflation, in case gas fill port has leakage, observing the inflation situation of surveying capsule can know, if the blowing pressure is too high, surveying capsule will break, to guarantee safety.

The bridge of the nose fixed mount of being made by rigid plastics [19] also is housed on main pipe [10] in addition, and when its anchor clamps unclamped, it can move forward and backward along main pipe [10], can be positioned on the main pipe outer wall when anchor clamps are tightened.

The esophageal lumen internal therapy conduit of this utility model inserts esophageal lumen, and the medicinal liquid when doing esophageal carcinoma chemotherapy and immunization therapy behind the airbag aeration of front and back flows to and saliva sucking-off situation as shown in Figure 3.As seen it is not only a kind of effective treatment means, and provides convenience to the mechanism of action of tumor for research chemotherapy and immune drug.

Embodiment 2:

See also Fig. 1 and Fig. 2, except that wherein main pipe [10] with the polyurethane manufacturing, all the other are all identical with embodiment 1, the esophageal lumen internal therapy main pipe property endured that obtains is good, the intubate operation is more convenient.

Claims (7)

1, a kind of esophageal lumen internal therapy conduit, comprise that one is suitable for inserting the main pipe [10] that the macromolecular material of esophagus is made by nasal cavity, it is characterized in that: this main pipe [10] is four cavities conduit pipes, four mutual isolated independent cavities are promptly arranged in the pipe, comprise and attract chamber [20], medicinal liquid splashes into chamber [22], preceding balloon inflation lumen [21] and rear gasbag inflatable chamber [23], the front end of main pipe [10] is the blunt conical head of real core [18] of sealing, two air bags of being close to main pipe [10] outer wall are arranged at the rear of conical head [18], be the preceding air bag [17] of nearly stomach end and the rear gasbag [12] of near mouthful of end, the leading edge of the trailing edge of pro-air bag [17] and rear gasbag [12] has radiopaque labelling [16] and [13], medicine liquid droplet portal [15] is arranged on main pipe [10] outer wall at labelling [16] rear, on main pipe [10] outer wall in labelling [13] the place ahead, there is medicinal liquid to attract hole [14], on main pipe [10] outer wall at rear gasbag [12] rear, there is saliva to attract hole [11], medicine liquid droplet portal [15] splash into chamber [22] with medicinal liquid and be connected, medicinal liquid attracts hole [14] and saliva to attract hole [11] to be connected with attracting chamber [20], preceding balloon inflation lumen [21] and rear gasbag inflatable chamber [23] are connected with preceding air bag [17] and rear gasbag [12] respectively, attract chamber [20], medicinal liquid splashes into chamber [22], before balloon inflation lumen [21] and rear gasbag inflatable chamber [23] tail end respectively with suction manifold [4], medicinal liquid splashes into arm [5], preceding airbag aeration arm [1] and rear gasbag inflation arm [8] are connected.

2, esophageal lumen internal therapy conduit according to claim 1 is characterized in that: the tail end of pro-airbag aeration arm [1] and rear gasbag inflation arm [8] has detection capsule [2] and [7] respectively, and the tail end in [2] and [7] of surveying capsule has check valve [3] and [6].

3, esophageal lumen internal therapy conduit according to claim 1 is characterized in that: have on main pipe [10] and can move forward and backward the bridge of the nose fixed mount [19] that also can be positioned on the main pipe along main pipe [10].

4, esophageal lumen internal therapy conduit according to claim 1 is characterized in that: suction manifold [4], medicinal liquid splash into arm [5], preceding airbag aeration arm [1] and rear gasbag inflation arm [8] are fixed in main pipe [10] by bunch block [9] rear end.

5, esophageal lumen internal therapy conduit according to claim 1, it is characterized in that: the spacing between labelling [13] and [16] is 100～150mm.

6, esophageal lumen internal therapy conduit according to claim 1, it is characterized in that: main pipe [10] is made by silastic material.

7, esophageal lumen internal therapy conduit according to claim 1, it is characterized in that: main pipe [10] is made by polyurethane material.

Images