CN108888854A - A kind of double sacculus perfusion conduits of interval adjustable and its application method - Google Patents
A kind of double sacculus perfusion conduits of interval adjustable and its application method Download PDFInfo
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- CN108888854A CN108888854A CN201811022360.6A CN201811022360A CN108888854A CN 108888854 A CN108888854 A CN 108888854A CN 201811022360 A CN201811022360 A CN 201811022360A CN 108888854 A CN108888854 A CN 108888854A
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- Prior art keywords
- conduit
- sacculus
- perfused
- interval adjustable
- double
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- 230000010412 perfusion Effects 0.000 title claims abstract description 61
- 238000000034 method Methods 0.000 title claims abstract description 20
- 238000002347 injection Methods 0.000 claims abstract description 59
- 239000007924 injection Substances 0.000 claims abstract description 59
- 239000012530 fluid Substances 0.000 claims abstract description 58
- 239000003814 drug Substances 0.000 claims description 23
- 229940079593 drug Drugs 0.000 claims description 19
- 230000003902 lesion Effects 0.000 claims description 13
- 239000007788 liquid Substances 0.000 claims description 10
- 239000002775 capsule Substances 0.000 claims description 6
- 244000043261 Hevea brasiliensis Species 0.000 claims description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 4
- 239000013013 elastic material Substances 0.000 claims description 4
- 229920003052 natural elastomer Polymers 0.000 claims description 4
- 229920001194 natural rubber Polymers 0.000 claims description 4
- 229920002635 polyurethane Polymers 0.000 claims description 4
- 239000004814 polyurethane Substances 0.000 claims description 4
- 239000000741 silica gel Substances 0.000 claims description 4
- 229910002027 silica gel Inorganic materials 0.000 claims description 4
- 230000000694 effects Effects 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 2
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 230000037361 pathway Effects 0.000 claims 1
- 238000001574 biopsy Methods 0.000 description 4
- 239000007789 gas Substances 0.000 description 4
- 229940088597 hormone Drugs 0.000 description 4
- 239000005556 hormone Substances 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 238000001861 endoscopic biopsy Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000002980 postoperative effect Effects 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 238000012323 Endoscopic submucosal dissection Methods 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 210000004400 mucous membrane Anatomy 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 201000003741 Gastrointestinal carcinoma Diseases 0.000 description 1
- 208000005168 Intussusception Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 210000003445 biliary tract Anatomy 0.000 description 1
- 210000000080 chela (arthropods) Anatomy 0.000 description 1
- 238000002052 colonoscopy Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 208000018554 digestive system carcinoma Diseases 0.000 description 1
- 238000012142 en-bloc resection Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 238000010827 pathological analysis Methods 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 208000037803 restenosis Diseases 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1011—Multiple balloon catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1011—Multiple balloon catheters
- A61M2025/1013—Multiple balloon catheters with concentrically mounted balloons, e.g. being independently inflatable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1011—Multiple balloon catheters
- A61M2025/1015—Multiple balloon catheters having two or more independently movable balloons where the distance between the balloons can be adjusted, e.g. two balloon catheters concentric to each other forming an adjustable multiple balloon catheter system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1052—Balloon catheters with special features or adapted for special applications for temporarily occluding a vessel for isolating a sector
Abstract
The present invention provides a kind of double sacculus perfusion conduits of interval adjustable and its application methods, including the first conduit, the second conduit, the proximal balloon for being fixed on the first distal end of catheter and the distal balloon catheter for being fixed on the second distal end of catheter；There are fluid injection chamber, the inflatable chamber through the first conduit and the cavity by the second conduit in first conduit, there is inflatable chamber in the second conduit, cavity extension catheter coaxial direction extends；Distance between proximal balloon and distal balloon catheter can be adjusted by enabling two conduit relative movements.
Description
Technical field
The present invention relates to gastroenterology the field of medical instrument technology, conduit is perfused in the double sacculus of especially a kind of interval adjustable
And its application method.
Background technique
Endoscopic submucosal dissection (Endoscopic submucosal dissection, ESD) occurs in recent years
It is minimally invasive mainly to carry out the scope removed under mucous membrane to the lesion greater than 2cm using various electric knives for one new treatment means
Technology.This technology realizes the en bloc resection of larger lesion, provides accurate pathological diagnosis by stages for lesion.Outside tradition
Section's operation is compared, and wound caused by ESD is smaller；Patient is subjected to the multiple treatment at multiple positions；Doctor can obtain complete group
Pathologic specimen is knitted for analysis；On the basis of eradicating tumour, preferably retain alimentary canal physiological function, hence it is evident that improve patient
Postoperative life quality is had become at present for the preferred treatment method of early gastrointestinal carcinoma and precancerous lesion including oesophagus,
With good potential applicability in clinical practice.
But since ESD excision mucous membrane area is big, postoperative common complication is ESD postoperative restenosis, in order to solve this
Hormone is perfused in the preoperative diseased region of giving of clinical practice ESD in problem.Because liquid can arbitrarily flow in enteron aisle biliary tract living, nothing
Method is fixed on desired zone, so usually patient can only be under lying status by hormone liquid injection patient's natural cavity at present
Diseased region, the disadvantage is that injection rate is big, the flowing of hormone liquid cannot effectively cover diseased region, bring to clinical practice operation tired
It is difficult.
Therefore it is a kind of liquid medicine can effectively be covered to specific region, and be not fixed zone length medical instrument it is urgent
It needs.
Summary of the invention
The purpose of the present invention is to design a kind of double sacculus perfusion conduits of interval adjustable and its application method, so that drug
Perfusion becomes controllable, and preoperative give when hormone is perfused in diseased region of effective solution ESD cannot effectively cover specific region, and not
The problem of fixed area length.
The present invention provides a kind of double sacculus of interval adjustable, and conduit is perfused, and conduit is perfused in the double sacculus of the interval adjustable
It is remote with second conduit is fixed on including the first conduit, the second conduit, the proximal balloon for being fixed on first distal end of catheter
The distal balloon catheter at end；Have in first conduit fluid injection chamber, through first conduit the first inflatable chamber by described second
The cavity of conduit has the second inflatable chamber in second conduit；First conduit and the second conduit can relatively move to adjust
Save the distance between the proximal balloon and the distal balloon catheter.
Conduit is perfused in the double sacculus of interval adjustable of the invention, and the proximal balloon and distal balloon catheter can in body cavities
To form semi-closed structure, drug is locked in semiclosed treatment space.
Conduit is perfused in the double sacculus of interval adjustable of the invention, and the fluid injection chamber can be to be run through outside second conduit
First conduit, is distributed side by side with the first inflatable chamber, and there is one to be located at the proximal end ball for the distal end of the fluid injection chamber at this time
The proximal end of the outlet of capsule distal end, first conduit has gas-charging connection and fluid injection connector, and the proximal end of second conduit has
Gas-charging connection；The fluid injection chamber is also possible to be distributed side by side with the second inflatable chamber, at this time the fluid injection through second conduit
The distal end of chamber has an outlet close to the distal balloon catheter proximal end, and the proximal end of first conduit has gas-charging connection, institute
The proximal end for stating the second conduit has gas-charging connection and fluid injection connector.
Conduit is perfused in the double sacculus of interval adjustable of the invention, and the distal end of first and second inflatable chamber is located at institute
Proximally and distally balloon interior is stated, and is communicated respectively with the proximally and distally balloon interior.
Conduit is perfused in the double sacculus of interval adjustable of the invention, and the sacculus is that elastic material includes silica gel, natural rubber
And polyurethane.
Conduit is perfused in the double sacculus of interval adjustable of the invention, can also include guidewire lumen in the second conduit.
Conduit is perfused in the double sacculus of interval adjustable of the invention, and guidewire lumen can run through entire second conduit.
Conduit is perfused in the double sacculus of interval adjustable of the invention, and guidewire lumen can originate in the proximal end of the distal balloon catheter,
End at the distal end of second conduit.
Conduit is perfused in the double sacculus of interval adjustable of the invention, and the proximal end of the second conduit can also connect seal wire connector.
The application method of the double sacculus perfusion conduits of interval adjustable of the invention, it is enterprising to be fixed on endoscope for the conduit
Enter human body, makes diseased region be in the proximal balloon and institute by adjusting the first conduit and the second conduit under scope effect
It states between distal balloon catheter, by gas-charging connection, the filled media into two sacculus makes balloon inflation to being more than human body natural respectively
The diameter of cavity will two sacculus be fixed in human body, then by fluid injection connector to diseased region discharge drug, take out after the completion
The medium sacculus in sacculus is contracted to original size backed off after random endoscope path way out.
The application method of the double sacculus perfusion conduits of interval adjustable of the invention, the proximal balloon and distal balloon catheter expansion
Semi-closed structure is formed in cavity afterwards, drug is limited in the semi-closed structure.
The application method of the double sacculus perfusion conduits of interval adjustable of the invention, the medium of the filling sacculus can be gas
Body or liquid.
The application method of the double sacculus perfusion conduits of interval adjustable of the invention can be adjusted again after first stationary remote sacculus
Proximal balloon is fixed behind position needed for first conduit reaches proximal balloon again.
Detailed description of the invention
Fig. 1 is the double sacculus perfusion conduits of interval adjustable in the intracorporal schematic diagram of people.
Fig. 2 is the structural schematic diagram of adjustable double sacculus perfusion conduits.
Fig. 3 A is one embodiment of adjustable double sacculus perfusion conduits.
Fig. 3 B is the cross-sectional view of adjustable double sacculus perfusion conduits shown in Fig. 3 A.
Fig. 3 C is the sectional view at adjustable double sacculus perfusion conduit C-C shown in Fig. 3 B.
Fig. 3 D is the sectional view at adjustable double sacculus perfusion conduit D-D shown in Fig. 3 B.
Fig. 3 E is the cross-sectional view after adjustable double sacculus perfusion conduits shown in 3B rotate by a certain angle.
Fig. 3 F is the sectional view at adjustable double sacculus perfusion conduit C-C shown in Fig. 3 E.
Fig. 3 G is the sectional view at adjustable double sacculus perfusion conduit D-D shown in Fig. 3 E.
Fig. 4 A is the cross-sectional view of another embodiment of adjustable double sacculus perfusion conduits.
Fig. 4 B is the sectional view at adjustable double sacculus perfusion conduit C-C shown in Fig. 4 A.
Fig. 4 C is the sectional view at adjustable double sacculus perfusion conduit D-D shown in Fig. 4 A.
Fig. 4 D is the cross-sectional view after adjustable double sacculus perfusion conduits shown in Fig. 4 A rotate by a certain angle.
Fig. 4 E is the sectional view at adjustable double sacculus perfusion conduit C-C shown in Fig. 4 D.
Fig. 4 F is the sectional view at adjustable double sacculus perfusion conduit D-D shown in Fig. 4 D.
Fig. 5 A is another embodiment of adjustable double sacculus perfusion conduits.
Fig. 5 B is the cross-sectional view of adjustable double sacculus perfusion conduits shown in Fig. 5 A.
Fig. 5 C is the sectional view at adjustable double sacculus perfusion conduit C-C shown in Fig. 5 B.
Fig. 5 D is the sectional view at adjustable double sacculus perfusion conduit D-D shown in Fig. 5 B.
Fig. 5 E is the cross-sectional view after adjustable double sacculus perfusion conduits shown in Fig. 5 B rotate by a certain angle.
Fig. 5 F is the sectional view at adjustable double sacculus perfusion conduit C-C shown in Fig. 5 E.
Fig. 5 G is the sectional view at adjustable double sacculus perfusion conduit D-D shown in Fig. 5 E.
Fig. 6 A is the cross-sectional view of another embodiment of adjustable double sacculus perfusion conduits.
Fig. 6 B is the sectional view at adjustable double sacculus perfusion conduit C-C shown in Fig. 6 A.
Fig. 6 C is the sectional view at adjustable double sacculus perfusion conduit D-D shown in Fig. 6 A.
Fig. 7 A is the cross-sectional view of another embodiment of adjustable double sacculus perfusion conduits.
Fig. 7 B is the sectional view at adjustable double sacculus perfusion conduit C-C shown in Fig. 7 A.
Fig. 7 C is the sectional view at adjustable double sacculus perfusion conduit D-D shown in Fig. 7 A.
Drawing reference numeral explanation
First conduit 1,11,21,31,41,51, the second conduit 2,12,22,32,42,52, proximal balloon 3,13,23,33,
43,53, distal balloon catheter 4,14,24,34,44,54, the first inflatable chamber 111,211,311,411,511, fluid injection chamber 112,212,
312,412,512, gas-charging connection 15,17,35,37, fluid injection connector 16,36, fluid injection outlet 18,28,38,48,58, the second inflation
Chamber 121,221,321,421,521, guidewire lumen 29,291,391,591.
Specific embodiment
Technical solution of the present invention is described in detail below in conjunction with attached drawing.It should be appreciated that specific reality described herein
Mode is applied only to explain the present invention, is not intended to limit the present invention.Scope of the present application is not by the limit of these embodiments
It is fixed, it is being subject to the range applied for a patent.It and is that clearer description is provided and enables to be familiar with this those skilled in the art to understand the application
Application content, illustrate in each section might not draw according to its opposite size, certain sizes and other scale dependents
Ratio regular meeting highlighted and the exaggeration that seems, and uncorrelated or unessential detail section is not also drawn completely, in the hope of the letter of diagram
It is clean.
The present invention provides a kind of double sacculus of interval adjustable, and conduit is perfused, and conduit is perfused in the double sacculus of the interval adjustable
It is remote with second conduit is fixed on including the first conduit, the second conduit, the proximal balloon for being fixed on first distal end of catheter
The distal balloon catheter at end；There is fluid injection chamber through the first inflatable chamber of first conduit and by described second in first conduit
The cavity of conduit has the second inflatable chamber in second conduit；First conduit and the second conduit can relatively move to adjust
Save the distance between the proximal balloon and the distal balloon catheter.
Conduit is perfused in the double sacculus of interval adjustable of the invention, and the proximal balloon and distal balloon catheter can in body cavities
To form semi-closed structure, drug is locked in semiclosed treatment space；There is one to be located at institute for the distal end of the fluid injection chamber
State the outlet of proximal balloon distal end.The specially described proximal balloon and distal balloon catheter are separately positioned on the both ends of diseased region, institute
It states proximal balloon and distal balloon catheter is filled after medium to be expanded to can be fixed on human body slightly larger than after human body natural's cavity diameter
It is interior, to form a semi-closed structure by two sacculus and the body cavities comprising diseased region, can be gone out by fluid injection
Mouth is connected to external fluid.
Conduit is perfused in the double sacculus of interval adjustable of the invention, and the distal end of first and second inflatable chamber is located at institute
Proximally and distally balloon interior is stated, and is communicated respectively with the proximally and distally balloon interior.
The double sacculus of interval adjustable of the invention are perfused conduits, the sacculus be elastic material include silica gel, natural rubber,
Polyurethane etc..
Conduit is perfused in the double sacculus of interval adjustable of the invention, can also include guidewire lumen in the second conduit, guidewire lumen can
To run through entire second conduit, the proximal end of the distal balloon catheter can also be originated in, end at the distal end of second conduit.
Conduit is perfused in the double sacculus of interval adjustable of the invention, and the fluid injection chamber can be to be run through outside second conduit
First conduit, is distributed side by side with the first inflatable chamber, and there is one to be located at the proximal end ball for the distal end of the fluid injection chamber at this time
The proximal end of the outlet of capsule distal end, first conduit has gas-charging connection and fluid injection connector, and the proximal end of second conduit has
Gas-charging connection；The fluid injection chamber is also possible to be distributed side by side with the second inflatable chamber, at this time the fluid injection through second conduit
The distal end of chamber has an outlet close to the distal balloon catheter proximal end, and the proximal end of first conduit has gas-charging connection, institute
The proximal end for stating the second conduit has gas-charging connection and fluid injection connector；It can be led to sacculus filled media by the gas-charging connection
Drug can be conveyed to lesion region by crossing the fluid injection connector.
Conduit is perfused in the double sacculus of interval adjustable of the invention, and the proximal end of the second conduit can also connect seal wire connector, lead to
Seal wire can be placed into the double sacculus perfusion conduits of the interval adjustable by crossing the seal wire connector.
The application method of the double sacculus perfusion conduits of interval adjustable of the invention, it is enterprising to be fixed on endoscope for the conduit
Enter human body, makes diseased region be in the proximal balloon and institute by adjusting the first conduit and the second conduit under scope effect
It states between distal balloon catheter, by gas-charging connection, the filled media into two sacculus makes balloon inflation to being more than human body natural respectively
The diameter of cavity will two sacculus be fixed in human body, then by fluid injection connector to diseased region discharge drug, take out after the completion
The medium sacculus in sacculus is contracted to original size backed off after random endoscope path way out.
The application method of the double sacculus perfusion conduits of interval adjustable of the invention, the proximal balloon and distal balloon catheter expansion
Semi-closed structure is formed in cavity afterwards, drug is limited in the semi-closed structure；The specially described proximal balloon and remote
End sacculus is separately positioned on the both ends of diseased region, and the proximal balloon and distal balloon catheter, which are filled after medium to be expanded to, to be slightly larger than
It can be fixed in human body after human body natural's cavity diameter, never by two sacculus and the body cavities shape comprising diseased region
At a semi-closed structure, can be connected to by fluid injection outlet with external fluid.
The application method of the double sacculus perfusion conduits of interval adjustable of the invention, the medium of the filling sacculus can be gas
Body or liquid.
The application method of the double sacculus perfusion conduits of interval adjustable of the invention can be adjusted again after first stationary remote sacculus
Proximal balloon is fixed behind position needed for first conduit reaches proximal balloon again.
As shown in Figures 1 to 7, which illustrate the conduits of embodiment of the present invention.
In non-limiting embodiment of the invention, the double sacculus perfusion conduits of interval adjustable include the first conduit, the
Two conduits, proximal balloon and distal balloon catheter.As shown in Figures 1 to 7, wherein proximal balloon 3,13,23,33,43,53 are fixed on
The distal end of one conduit 1,11,21,31,41,51, distal balloon catheter 4,14,24,34,44,54 are fixed on the second conduit 2, and 12,22,
32,42,52 distal end, the first conduit 1,11,21,31,41,51 are covered on the second conduit of part 2,12,22,32,42,52,
That is 1,11,21,31,41,51 and the second conduit 2,12,22,32,42,52 of the first conduit is designed using intussusception.
As shown in Fig. 3 A-3G, wherein Fig. 3 A is one embodiment of adjustable double sacculus perfusion conduits, and Fig. 3 B is Fig. 3 A institute
The cross-sectional view of the adjustable double sacculus perfusion conduits shown, Fig. 3 C and 3D are adjustable double sacculus perfusion conduits shown in Fig. 3 B respectively
Sectional view at C-C and at D-D；Fig. 3 E is the section view after adjustable double sacculus perfusion conduits shown in 3B rotate by a certain angle
Figure, Fig. 3 F and 3G are the sectional view at adjustable double sacculus perfusion conduit C-C shown in Fig. 3 E and at D-D respectively.First conduit
Comprising three be separated from each other the cavities through the first conduit 11 in 11, respectively the first inflatable chamber 111, fluid injection chamber 112 and logical
Cross the cavity of the second conduit 12；Wherein 111 proximal end of the first inflatable chamber is connected with gas-charging connection 15, is distally one and proximal balloon
13 connected inflation outlets, inflation outlet are arranged inside proximal balloon 13, are filled by the gas-charging connection 15 by first
Air cavity 111 exports proximally sacculus 13 from the inflation and inflates；112 proximal end of fluid injection chamber is connected with fluid injection connector 16, is distally located at
The distal end of proximal balloon 13 and the fluid injection outlet 18 for being equipped with a discharge medicine, drug passes through fluid injection by the fluid injection connector 16
Chamber 112 reaches lesion region from fluid injection outlet 18.Second conduit 12 passes through first by the cavity in the first conduit 11 and leads
Pipe 11, both ends are respectively positioned on the outside of the both ends of the first conduit 11, i.e., the first conduit 11 is covered on outside the second conduit of part 12；Second
Include the second inflatable chamber 121 in conduit 12,121 proximal end of the second inflatable chamber is connected with gas-charging connection 17, distally for one with
The connected inflation outlet of distal balloon catheter 14, by the gas-charging connection 17 by the second inflatable chamber 121 from inflation outlet to
Distal balloon catheter 14 is inflated.The connector and conduit in the present invention are integrally formed, first conduit 11 and the second conduit
12 are made of material slightly flexible, can be metal tube or plastic tube etc..Sacculus uses elastic material, including silica gel, natural
Rubber, polyurethane etc. can avoid the injury to human body on the basis of reaching accurate leak stopping.
The first inflatable chamber 111, fluid injection chamber 112 in the present invention and the cavity for passing through the second conduit 12 can be arranged for a word
It opens, but preferably the first inflatable chamber 111, fluid injection chamber 112 and passes through the second conduit 12 as shown in Fig. 3 C, 3D and Fig. 3 F, 3G
Cavity distribution triangular in shape, so that the diameter of the first conduit can be made to the greatest extent may be used under the premise of guaranteeing that three cavity internal diameters are sufficiently large
Can be small, to be easier the cavity into human body, and effectively reduce a possibility that sense of discomfort slightly is brought to patient excessively because of caliber.
As shown in Figure 1 when in use, conduit is perfused in double sacculus to the double sacculus perfusion conduits of interval adjustable provided by the invention
It is inserted into the state of sacculus unaerated in the pincers road of endoscope and enters human body, the lesion for needing fluid injection is determined first under scope
Then position adjusts 1,11,21,31,41,51 and the second conduit 2,12,22,32,42,52 of the first conduit and makes at diseased region
Between 1,11,21,31,41,51 and the second conduit 2,12,22,32,42,52 of the first conduit, by gas-charging connection 15,17,
35,37 into two sacculus filled media make balloon inflation to be more than human body natural's cavity diameter will two sacculus fix
Drug is discharged to diseased region in human body, then through fluid injection connector 16,36, the medium sacculus extracted out in sacculus after the completion is shunk
To original size backed off after random endoscope path way.
The medium of the filling sacculus can be gas or liquid, including nitrogen, empty gas and water etc..
Specific operate can fix proximal balloon 3 again for first stationary remote sacculus 4,14,24,34,44,54, and 13,23,
33,43,53 mobile double sacculus perfusion conduits make the distal balloon catheter 4,14 connected with the second conduit 2,12,22,32,42,52,
24,34,44,54 cross lesion locations, and the distal end for being proximally located at lesion locations of distal balloon catheter 4,14,24,34,44,54；So
Afterwards by the gas-charging connection 15,17,35,37 that is connected with the second conduit 2,12,22,32,42,52 to distal balloon catheter 4,14,24,
34,44,54 inflations or fluid injection make it be expanded to the diameter that the diameter of sacculus is greater than place body cavities, at this time distal balloon catheter 4,
14,24,34,44,54 have been fixed on the distal end of lesion region；Then adjust the first conduit 1,11,21,31,41,51 relative to
The position of second conduit 2,12,22,32,42,52, so that the distal end of proximal balloon 3,13,23,33,43,53 is located at lesion region
Proximal end, need at this time fluid injection treat diseased region be in proximal balloon 3,13,23,33,43,53 and distal balloon catheter 4,14,
Between 24,34,44,54, by the gas-charging connection 15 that is connected with proximal balloon 3,13,23,33,43,53 proximally sacculus 3,13,
The diameter that 23,33,43,53 inflations or fluid injection make it be expanded to the diameter of sacculus greater than place body cavities, proximal balloon 3,13,
23,33,43,53 have been fixed on the proximal end of lesion region；Drug or liquid by with the first conduit 1,11,21,31,41,51
Connected fluid injection connector 16,36 proximally sacculus 3, the fluid injection outlet 18,28,38,48,58 of 13,23,33,43,53 end into
Enter human body；Kept for a period of time, it is ensured that after drug extracts in sacculus out medium after being absorbed by the body shrinks sacculus automatically
Exit endoscope channel.Because of the presence of proximal balloon 3,13,23,33,43,53 and distal balloon catheter 4,14,24,34,44,54, medicine
Object is locked between two sacculus, so patient holds the acceptable treatment of the state for being seated or stand；Simultaneously as two balls
The flowing of the drug of capsule limitation, therefore the not loss occurrence of drug, required infusion of medicine amount are smaller；And it is being seated or is standing
In the state of, drug is influenced by gravity, and relative to the state to lie low, lesser amount of drug just can effectively cover proximal end ball
All diseased regions between capsule 3,13,23,33,43,53 and distal balloon catheter 4,14,24,34,44,54.
Double sacculus perfusion conduit of the invention can also be first fixed proximal balloon 3,13,23,33,43,53 when in use
Afterwards by adjusting the second conduit 2,12,22,32,42,52 to the mode of stationary remote sacculus 4,14,24,34,44,54 again
It completes.
Using set between 1,11,21,31,41,51 and the second conduit 2,12,22,32,42,52 of the first conduit in the present invention
Folded design, and distal end one sacculus of each self-retaining of two conduits, it is only necessary to adjust between two conduits can realize and adjust sacculus
Away from can also be achieved and realize the function that is perfused between two sacculus using injection liquid, operate effective and safer.
The double sacculus perfusion conduits of interval adjustable of the invention are suitable for the biopsy channel that diameter is greater than 2.8mm.Conventional
The endoscopes such as gastroscope, colonoscopy, minimum biopsy channel size are generally 2.8mm, and the double sacculus perfusions of interval adjustable of the invention are led
The working diameter of pipe is less than 2.8mm, it can the endoscope of cooperation biopsy channel 2.8mm or more is suitable for almost all of
Biopsy channel.
It is different from Fig. 3 A-3G, as shown in figs 6 a-6 c, fluid injection chamber 412 can not also in the first conduit 41, but
In second conduit 42, runs through second conduit 42, be distributed side by side with the second inflatable chamber 421, the fluid injection chamber 412 is remote at this time
Hold the fluid injection outlet 48 that there is one close to 44 proximal end of distal balloon catheter.Preferably, fluid injection outlet 48 is that the second conduit 42 exists
A notch between proximal balloon 43 and distal balloon catheter 44 on side wall.
In non-limiting embodiment of the invention, as shown in Fig. 4 A-4F and Fig. 5 A-5G, may be used also in the second conduit 22,32
To include guidewire lumen 29,39, wherein can be by there is the seal wire for guiding entire product to required position.Guidewire lumen 29 can be such as figure
It is only located at the distal end of the second conduit 22 shown in 4A-4F, that is, originates in the proximal end of distal balloon catheter 24, terminates at the remote of the second conduit 22
End, entire second conduit 32 can also be run through as shown in Fig. 5 A-5G, that is, originates in the proximal end of the second conduit 32, terminates at second
The distal end of conduit 32.
As shown in figs. 4 a-4f, wherein Fig. 4 A be adjustable double sacculus perfusion conduit another embodiment cross-sectional view, figure
4B and 4C is the sectional view at adjustable double sacculus perfusion conduit C-C shown in Fig. 4 A and at D-D respectively, and Fig. 4 D is shown in Fig. 4 A
Adjustable double sacculus perfusion conduits rotate by a certain angle after cross-sectional view, Fig. 4 E and 4F are adjustable double shown in Fig. 4 D respectively
The sectional view at conduit C-C and at D-D is perfused in sacculus.Guidewire lumen 29 is only in the distal end of the second conduit 22.Second conduit 22 at this time
Ending this section to 24 proximal end of distal balloon catheter since its proximal end is single cavity structure, only one inflatable chamber in the second conduit 22
221；Terminate since the proximal end of distal balloon catheter 24 to the distal end of the second conduit 22, the second conduit 22 is double cavity structure, in addition to the
It further include guidewire lumen 291 except two inflatable chambers 221.Seal wire can rise since the proximal end of distal balloon catheter 24 across guidewire lumen 291
To guiding function, in use, seal wire prolongs endoscopic biopsy channel and is previously inserted predetermined position into the human body, then will
Seal wire enters guidewire lumen 291 from the distal catheter end face of instrument distal balloon catheter 24, penetrates endoscopic biopsy channel, then seal wire from
The proximal end of distal balloon catheter 24 is pierced by guidewire lumen 291.Seal wire cavity rises, terminates in the forward and backward of distal balloon catheter 24, and seal wire guides distance
It is short.At this moment, entire instrument will be pushed to required position under seal wire guidance.As shown in Fig. 5 A-5G, wherein Fig. 5 A is adjustable
Another embodiment of the double sacculus perfusion conduits of formula, Fig. 5 B are the cross-sectional views of adjustable double sacculus perfusion conduits shown in Fig. 5 A,
Fig. 5 C and 5D are the sectional view at adjustable double sacculus perfusion conduit C-C shown in Fig. 5 B and at D-D respectively, and Fig. 5 E is Fig. 5 B institute
The cross-sectional view after conduits rotate by a certain angle is perfused in the adjustable double sacculus shown, and Fig. 5 F and 5G are adjustable shown in Fig. 5 E respectively
Sectional view at double sacculus perfusion conduit C-C and at D-D.Guidewire lumen 391 runs through entire second conduit 32, in the second conduit 32
There are two connectors, respectively gas-charging connection 37 and seal wire connector 39 for proximal end connection；Gas-charging connection 37 and filling in the second conduit 32
Air cavity is connected, and the distal end of inflatable chamber is the inflation being connected with distal balloon catheter 34 outlet, and inflation outlet is arranged in distal end ball
Inside capsule 34, is exported from the inflation to distal balloon catheter 34 and inflated by the second inflatable chamber 321 by the gas-charging connection 37；It leads
Threaded Connector Coupling 39 is connected with guidewire lumen 391, and the distal tip that the distal end of guidewire lumen 391 is located at the second conduit 32 is one outlet, leads
Silk setting is being crossed in guidewire lumen 391.Because seal wire cavity is from the distal end of the entire instrument i.e. catheter end of 34 distal end of distal balloon catheter
Face starts, and extends at the proximal guidewire connector 39 of entire instrument.When in use, seal wire prolongs endoscopic biopsy channel and is pre-placed
The predetermined position in human body, then by seal wire stay in external one end from the distal end of entire instrument be inserted into guidewire lumen 391, then again from
Proximal guidewire connector 39 is pierced by guidewire lumen 391, and instrument can be pushed to predetermined position along seal wire.It can compared to shown in Fig. 4 A
Conduit is perfused in the double sacculus of mode, because seal wire is inside entire instrument, the distance of guidance is longer.
Different from Fig. 5 A-5G, as shown in Figure 7 A-7C, fluid injection chamber 512 is led in the second conduit 52 through described second
Pipe 52 is distributed side by side with the second inflatable chamber 521, and the distal end of the fluid injection chamber 512 has the close distal balloon catheter at this time
The fluid injection outlet 58 of 54 proximal ends.Preferably, fluid injection outlet 58 is the second conduit 52 between proximal balloon 53 and distal balloon catheter 54
A notch on side wall.
Claims (18)
1. conduit is perfused in a kind of double sacculus of interval adjustable, which is characterized in that conduit packet is perfused in the double sacculus of the interval adjustable
It includes the first conduit, the second conduit, the proximal balloon for being fixed on first distal end of catheter and is fixed on second distal end of catheter
Distal balloon catheter；
There are fluid injection chamber, the first inflatable chamber through first conduit and the chamber by second conduit in first conduit
There is the second inflatable chamber in road in second conduit；First conduit and the second conduit can relatively move described close to adjust
Hold the distance between sacculus and the distal balloon catheter.
2. conduits are perfused in the double sacculus of interval adjustable according to claim 1, which is characterized in that the proximal balloon and remote
End sacculus can form semi-closed structure in body cavities, and drug is locked in semiclosed treatment space.
3. conduit is perfused in the double sacculus of interval adjustable according to claim 1, which is characterized in that the fluid injection chamber is described
Run through first conduit outside second conduit, is distributed side by side with the first inflatable chamber.
4. conduit is perfused in the double sacculus of interval adjustable according to claim 1, which is characterized in that the fluid injection chamber runs through institute
The second conduit is stated, is distributed side by side with the second inflatable chamber.
5. conduit is perfused in the double sacculus of interval adjustable according to claim 3, which is characterized in that the distal end of the fluid injection chamber
It is located at the outlet of the proximal balloon distal end with one.
6. conduit is perfused in the double sacculus of interval adjustable according to claim 4, which is characterized in that the distal end of the fluid injection chamber
Outlet with one close to the distal balloon catheter proximal end.
7. conduit is perfused in the double sacculus of interval adjustable according to claim 1, which is characterized in that described first and second fill
The distal end of air cavity is located at the proximally and distally balloon interior, and communicates respectively with the proximally and distally balloon interior.
8. conduit is perfused in the double sacculus of interval adjustable according to claim 1, which is characterized in that the sacculus is elastic material
Material includes silica gel, natural rubber and polyurethane.
9. conduits are perfused in the double sacculus of interval adjustable according to claim 1, which is characterized in that can be in the second conduit
Include guidewire lumen.
10. conduit is perfused in the double sacculus of interval adjustable according to claim 5, which is characterized in that guidewire lumen can run through
Entire second conduit.
11. conduit is perfused in the double sacculus of interval adjustable according to claim 5, which is characterized in that guidewire lumen can originate
In the proximal end of the distal balloon catheter, end at the distal end of second conduit.
12. conduit is perfused in the double sacculus of interval adjustable according to claim 3, which is characterized in that first conduit
Proximal end has gas-charging connection and fluid injection connector, and the proximal end of second conduit has gas-charging connection.
13. conduit is perfused in the double sacculus of interval adjustable according to claim 4, which is characterized in that first conduit
Proximal end has gas-charging connection, and the proximal end of second conduit has gas-charging connection and fluid injection connector.
14. conduit is perfused in the double sacculus of interval adjustable according to claim 7, which is characterized in that the proximal end of the second conduit
Seal wire connector can also be connected.
15. a kind of application method of the double sacculus perfusion conduits of interval adjustable described in claim 1, which is characterized in that will be described
Conduit, which is fixed on endoscope, enters human body, makes diseased region by adjusting the first conduit and the second conduit under scope effect
Between the proximal balloon and the distal balloon catheter, by gas-charging connection, into two sacculus, filled media makes ball respectively
Capsule be expanded to more than human body natural's cavity diameter will two sacculus be fixed in human body, then by fluid injection connector to lesion
Position release drug, the medium sacculus extracted out in sacculus after the completion are contracted to original size backed off after random endoscope path way.
16. according to the method for claim 15, which is characterized in that in cavity after the proximal balloon and distal balloon catheter expansion
Middle formation semi-closed structure, drug is limited in the semi-closed structure.
17. according to the method for claim 15, which is characterized in that the medium of the filling sacculus can be gas or liquid
Body.
18. according to the method for claim 15, which is characterized in that the first conduit can be adjusted again after first stationary remote sacculus
So that proximal balloon fixes proximal balloon after reaching required position again.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811022360.6A CN108888854A (en) | 2018-09-03 | 2018-09-03 | A kind of double sacculus perfusion conduits of interval adjustable and its application method |
| PCT/CN2019/098303 WO2020048257A1 (en) | 2018-09-03 | 2019-07-30 | Two-balloon perfusion catheter with adjustable spacing and usage method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811022360.6A CN108888854A (en) | 2018-09-03 | 2018-09-03 | A kind of double sacculus perfusion conduits of interval adjustable and its application method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108888854A true CN108888854A (en) | 2018-11-27 |
Family
ID=64359629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811022360.6A Pending CN108888854A (en) | 2018-09-03 | 2018-09-03 | A kind of double sacculus perfusion conduits of interval adjustable and its application method |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN108888854A (en) |
| WO (1) | WO2020048257A1 (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110339462A (en) * | 2019-07-15 | 2019-10-18 | 温州医科大学附属第一医院 | Endoscope guidance it is lower can fluid injection foley's tube |
| WO2020048257A1 (en) * | 2018-09-03 | 2020-03-12 | 南微医学科技股份有限公司 | Two-balloon perfusion catheter with adjustable spacing and usage method thereof |
| CN115349915A (en) * | 2022-10-19 | 2022-11-18 | 首都医科大学附属北京潞河医院 | A rubble trapping apparatus for urinary system calculus rubble calculus extraction |
| CN117065187A (en) * | 2023-09-05 | 2023-11-17 | 宁波韦科医疗科技有限公司 | Distance-adjustable double-plugging balloon microcatheter |
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Also Published As
| Publication number | Publication date |
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| WO2020048257A1 (en) | 2020-03-12 |
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Address after: 210032 10 hi tech three road, hi tech Industrial Development Zone, Pukou District, Nanjing, Jiangsu Applicant after: Nanwei Medical Technology Co., Ltd Address before: 210032 10 hi tech three road, hi tech Industrial Development Zone, Pukou District, Nanjing, Jiangsu Applicant before: Micro-Tech (Nanjing) Co., Ltd. |