CN2299318Y

CN2299318Y - Counterflow chromatograph

Info

Publication number: CN2299318Y
Application number: CN 97202779
Authority: CN
Inventors: 张天佑
Original assignee: BEIJING INSTITUTE OF NEW TECHNOLOGY APPLICATIONS
Current assignee: BEIJING INSTITUTE OF NEW TECHNOLOGY APPLICATIONS
Priority date: 1997-03-28
Filing date: 1997-03-28
Publication date: 1998-12-02
Anticipated expiration: 2007-03-28

Abstract

The utility model relates to a non-carrier liquid distributing counterflow chromatographic apparatus, particularly a counterflow chromatograph for an orthogonal axis using the action of a three-dimensional centrifugal force field. A constant phase in the large-caliber spiral pipe column of the counterflow chromatograph does a revolution motion around a revolution axis in a horizontal plane and does a rotation motion around a rotation axis in a vertical plane to obtain a constant and high retention value so that the utility model enhances the sampling size of samples and enlarges the species of separated samples. Two separating units are arranged on the rotating frame of the apparatus so that the utility model enlarges the capacity of the separating tube of the apparatus occupying a same space volume two times and effectively raises the operating stability of the apparatus, and meanwhile, each separating unit is provided with a twist releasing unit to avoid a phenomenon that four fluorine tubes are twisted with each other so that the separating quality of the samples is enhanced.

Description

Counter-current chromatograph

The utility model belongs to the compartment analysis instrument field, specifically relates to a kind of no-load body fluid liquid and distributes the adverse current chromatogram instrument.

At present the domestic existing counter-current chromatograph all is the stationary phase that is used for support liq of using the bidimensional centrifugal force field, the little axis that is the center shaft axis of instrument and the spiral pipe that sample separation is used is parallel to each other, spiral tube is made revolution does time rotational formation to the centrifugal force field that forms with it centrifugal force field and is coexisted in the plane, the suffered component of the particle of spiral liquid in pipe with make a concerted effort all in same plane, to constitute plane force system.Facts have proved, in plane force system, only should use small-bore spiral tube so that obtain more stable stationary phase, and use the large-caliber spiral tubing string, in plane force system, the stationary phase stability in the post is very poor, do not reach the experiment purpose of compartment analysis, therefore be not used.

The purpose of this utility model is to provide a kind of no-load body fluid liquid to distribute counter-current chromatograph, and the stationary phase in the large-caliber spiral tubing string of its use can obtain stable high retention under relatively low speed conditions, and can improve the sample size of sample.

For achieving the above object, the utility model is designed to the X-axis CPC instrument of applying three-dimensional effect of centrifugal force, and the central shaft of its rotating frame unit is vertically set on instrument central authorities, constitutes instrument revolution center line; A separative element that twines the large-caliber spiral pipe is respectively arranged in the both sides of rotating frame, and be furnished with one and separate the strand unit with separative element is done the reverse sync rotation; The centrifugal force field of separative element when central shaft is done revolution done the three-dimensional field of force of the orthogonal formation of centrifugal force field of time rotational with it around little axle, in the large-caliber spiral tubing string the suffered component of liquid with make a concerted effort in three dimensions formation space force system.

The two ends that separative element is conciliate the strand unit all have loose piece that they are fixed on the rotating frame.

The utility model has the advantages that: one, because the effect of separative element applying three-dimensional centrifugal force field makes the stable high retention of the on-stream acquisition of stationary phase in the large-caliber spiral tubing string, thereby improved the sample size of sample, enlarged the kind of sample separation.Two, be provided with two separative elements on the rotating frame, the separator tube capacity of the instrument of same duty volume added be twice, and exempted and used the required weight accessory of separator tube, improved the operation stability of instrument effectively.Three,, thereby install, dismantle very convenient owing to separative element reconciliation strand unit is fixed on the rotating frame by loose piece.Therefore separative element can exchange according to centrosymmetric principle with the installation site of separating the strand unit, separate the different installation site of spiral pipe on rotating frame, can make the particle of liquid in the tubing string be subjected to the effect in the differentiated three-dimensional field of force, this just provides possibility for the experimenter selects different experimental conditions.Four, because each separative element all disposes one and separates the strand unit, four fluorine tube is not beaten strand, makes whole sample to carry out in free of contamination airtight four fluorine tube, thereby has improved the disintegrate-quality of sample.

Accompanying drawing one is the utility model instrument master pseudosection.

Accompanying drawing two is that the separative element of the utility model instrument is conciliate strand unit top plan view.

Below in conjunction with accompanying drawing embodiment of the present utility model is described in further detail.

Shown in figure one, X-axis CPC instrument of the present utility model comprises casing unit [1], electric motor units [2], rotating frame unit [3], strand unit [6], [7] are separated in separative element [4], [5].([6] see figure two).

The central shaft [8] of rotating frame unit [3] is vertically set on instrument central authorities, constitutes instrument revolution center line.The two ends of this central shaft are by bearing [9], [10] location, and thrust bearing [11] is equipped with in bearing [10] lower end; In fixing conical gear [12] both sides a planetary conical cone gear [13], [14] are arranged respectively, their other end all is equipped with little synchronizing jugged a wheel [15], [16]; Central shaft [8] is a big toothed wheel [17] synchronously bottom, is connected with electric motor units [2] by the wide cut cog belt; Central shaft [8] both sides respectively are equipped with a separative element [4], [5] and one and are separated strand unit [6], [7], little synchronizing jugged wheel the [18] of separative element, [19] be by little synchronizing jugged wheel the [15], [16] engagement with the planetary conical cone gear [13] that is installed in rotating frame [3] below, [14] one ends of cog belt in a narrow margin, planetary conical cone gear [13], [14] then with fixedly conical gear [12] engagement.During running, central shaft [8] driven rotary framework [3] rotation, planetary conical cone gear [13], [14] are along with rotating frame revolves round the sun, begin rotation simultaneously, and drive little synchronizing jugged wheel the [15], [16] and rotate, by cog belt drives separative element [4] in a narrow margin, rotate [5], do to revolve round the sun around central shaft [8] in separative element [4], [5] like this, and spinning motion is made in axle [20], [21] from childhood around each again again.

Shown in figure two, a loose piece [22], [23] respectively are equipped with in the two ends of separative element [4], with screw two loose pieces are fixed on the rotating frame; A loose piece [24], [25] respectively are equipped with in the two ends of separating strand unit [6], with screw two loose pieces are fixed on the rotating frame.Spur gear [26] on the separative element [4] and spur gear [27] engagement of separating on the strand unit [6].The large diameter four fluorine tube [28] of separative element [4] is introduced drum core [30] by interior width of cloth wheel [29] one apertures, layering, closely be wrapped on the bulging core side by side, taking turns another aperture by the interior width of cloth then draws, its leading-in end connects the little internal diameter four fluorine tube of feed liquor [35], its exit connects the little internal diameter four fluorine tube of fluid [31], these two little internal diameter four fluorine tubes enter into the centre of little axle side by side from the side opening of little axle [20], draw from the outer end of little axle again, enter the centre of the little axle [32] of separating strand unit [6] then side by side, after passing, enter little axle [21] the inner of separative element [5].The little internal diameter four fluorine tube of feed liquor [35] is passed by the outer end of little axle [21] in advance, after the little internal diameter four fluorine tube of fluid [31] is passed by the side opening of little axle [21], cut off, be connected with the leading-in end of the large diameter four fluorine tube of separative element [5], then, the exit of large diameter four fluorine tube continues to connect the little internal diameter four fluorine tube of fluid [31]; The little internal diameter four fluorine tube of fluid [31] enters little axle centre by the side opening of little axle [21] again, and draw by the outer end of little axle, enter the little axle [33] of separating strand unit [7] side by side with the little internal diameter four fluorine tube of feed liquor, enter the stationary pipes [34] (seeing figure one) in the central shaft [8] at last, and pass the external unit that enters this instrument in the pipe thus.During operation, the spur gear [26] on the separative element [4] drives the spur gear of separating on the line unit [6] [27] and rotates, and separates the little axle [32] of strand unit [6] the little axle [20] of separative element [4] is not only done revolution but also done the reverse sync rotation.Separative element [5] conciliate strand unit [7] identical with its structure and with its in like manner.

Claims

1. a no-load body fluid liquid distributes counter-current chromatograph, comprise the casing unit, electric motor units, the rotating frame unit, separative element, it is characterized in that: it is the X-axis CPC instrument of applying three-dimensional effect of centrifugal force, and the central shaft of its rotating frame unit [8] is vertically set on instrument central authorities, constitutes instrument revolution center line; Separative element [4], [5] of twining the large-caliber spiral pipe are respectively arranged in the rotating frame both sides, and be furnished with one separately and do separating of reverse sync rotation with separative element and twist unit [6], [7]; The centrifugal force field of separative element when central shaft is done revolution and the three-dimensional field of force of the orthogonal formation of centrifugal force field of making time rotational around its little axle, in the spiral tube the suffered component of liquid with make a concerted effort then in three dimensions, to constitute space force system.

2. counter-current chromatograph according to claim 1, it is characterized in that there is a fixedly conical gear [12] at place, location, central shaft [8] below, planetary conical cone gear [13], [14] engagement with its both sides, the other end of planetary conical cone gear [13], [14] respectively has little synchronizing jugged a wheel [15], [16], by little synchronizing jugged wheel the [18], [19] engagement of cog belt and separative element [4], [5] in a narrow margin.

3. counter-current chromatograph according to claim 2 is characterized in that central shaft [8] has a big toothed wheel [17] synchronously bottom, is connected with electric motor units [2] by the wide cut cog belt.

4. counter-current chromatograph according to claim 3 is characterized in that the two ends of separative element reconciliation strand unit all have loose piece to be fixed on the rotating frame.

5. counter-current chromatograph according to claim 4, it is characterized in that separating strand unit [6] little axle [32] and a spur gear [27] arranged, spur gear [26] engagement of this spur gear and separative element [4] makes the little axle [32] of separating the strand unit do the reverse sync rotation to the little axle [20] of separative element; Separative element [5] is identical with [4] structure, and it is identical with [6] structure to separate strand unit [7].

6. counter-current chromatograph according to claim 5 is characterized in that it is large diameter four fluorine tube [28] that separative element [4] drum core [30] is gone up what twine, and its leading-in end connects little internal diameter four fluorine tube of feed liquor [35], and its exit connects little internal diameter four fluorine tube of fluid [31].