CN221432691U - Automatic dilution configuration system for liquid medicament - Google Patents
Automatic dilution configuration system for liquid medicament Download PDFInfo
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- CN221432691U CN221432691U CN202323572597.0U CN202323572597U CN221432691U CN 221432691 U CN221432691 U CN 221432691U CN 202323572597 U CN202323572597 U CN 202323572597U CN 221432691 U CN221432691 U CN 221432691U
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- barrel
- stirring barrel
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- pipeline
- solute
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- 239000007788 liquid Substances 0.000 title claims abstract description 56
- 239000003814 drug Substances 0.000 title claims abstract description 29
- 238000010790 dilution Methods 0.000 title claims abstract description 21
- 239000012895 dilution Substances 0.000 title claims abstract description 21
- 238000003756 stirring Methods 0.000 claims abstract description 74
- 239000002904 solvent Substances 0.000 claims abstract description 55
- 239000011229 interlayer Substances 0.000 claims description 8
- 238000005303 weighing Methods 0.000 claims description 7
- 238000004140 cleaning Methods 0.000 claims description 6
- 229940079593 drug Drugs 0.000 abstract description 3
- 239000000243 solution Substances 0.000 description 26
- 238000002360 preparation method Methods 0.000 description 16
- 238000005406 washing Methods 0.000 description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- 238000010438 heat treatment Methods 0.000 description 5
- 239000003507 refrigerant Substances 0.000 description 5
- 238000010586 diagram Methods 0.000 description 3
- 238000007599 discharging Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000002699 waste material Substances 0.000 description 3
- 238000001816 cooling Methods 0.000 description 2
- 238000012864 cross contamination Methods 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- -1 1 agitator Substances 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 230000003670 easy-to-clean Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 239000002455 scale inhibitor Substances 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000000844 transformation Methods 0.000 description 1
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- Accessories For Mixers (AREA)
Abstract
The utility model discloses an automatic dilution configuration system for liquid medicines, which comprises: the device comprises a stirring barrel, a solvent barrel, a solute barrel and a controller, wherein the stirring barrel is respectively communicated with the solvent barrel and the solute barrel, a solvent pump and a first electric ball valve are arranged on a solvent pipeline which is communicated with the solvent barrel and the stirring barrel, a solute pump and a second electric ball valve are arranged on a solute pipeline which is communicated with the solute barrel and the stirring barrel, a stirrer is arranged at the top of the stirring barrel, a liquid discharge pipeline is arranged at the bottom of the stirring barrel, a first weight scale is arranged at the bottom of the stirring barrel, and the first electric ball valve, the second electric ball valve, the solvent pump, the solute pump, the stirrer and the first weight scale are respectively electrically connected with the controller; the system has the characteristics of high configuration efficiency, good safety and high accuracy.
Description
Technical Field
The utility model relates to the field of liquid medicament preparation systems, in particular to an automatic dilution preparation system for liquid medicaments.
Background
In the past, the dilution configuration of liquid medicament generally adopts the manpower to carry out the configuration by hand, and the manual configuration mainly has the configuration inefficiency, and the medicament is liable to cause personnel's injury, stirring inhomogeneous scheduling problem. Therefore, at present, an industrial automatic solution preparation machine is mainly used for preparing the solution medicament in the market, but in the actual preparation process, the following problems still exist:
(1) The dead volume of the solvent conveying pipeline cannot be completely discharged into the solution barrel, so that the configuration accuracy is poor;
(2) In some medicament preparation processes, the temperature needs to be monitored and controlled in real time, and the solution preparation machine does not have a temperature control function;
(3) The heating stirring barrel on the market adopted by the solution preparation machine is a traditional coil pipe for heating, and the coil pipe is not easy to clean and is easy to cause cross contamination;
(4) The split charging system of the solution preparing machine is conveyed by a pump, and the pump conveying has the defects that the solution cannot be completely emptied to cause waste of feed liquid, and the residual solution in the pump has great pollution to the environment when the preparing system is cleaned;
Accordingly, there is a strong need to provide an automated dilution configuration system for liquid medicaments to solve the above-mentioned problems.
Disclosure of Invention
To achieve the above object, the present inventors provide an automated dilution configuration system for liquid medicines, comprising: the device comprises a stirring barrel, a solvent barrel, a solute barrel and a controller, wherein the stirring barrel is respectively communicated with the solvent barrel and the solute barrel, a solvent pump and a first electric ball valve are arranged on a solvent pipeline through which the solvent barrel is communicated with the stirring barrel, a solute pump and a second electric ball valve are arranged on a solute pipeline through which the solute barrel is communicated with the stirring barrel, a stirrer is arranged at the top of the stirring barrel, a liquid discharge pipeline is arranged at the bottom of the stirring barrel, and a first weight scale is arranged at the bottom of the stirring barrel, and the first electric ball valve, the second electric ball valve, the solvent pump, the solute pump, the stirrer and the first weight scale are respectively electrically connected with the controller.
As a preferable structure of the utility model, the utility model further comprises a receiving barrel, a liquid discharge pipeline arranged at the bottom of the stirring barrel is communicated with the receiving barrel, a third electric ball valve is arranged on the liquid discharge pipeline, a second weight measuring scale is arranged at the bottom of the receiving barrel, and the third electric ball valve and the second weight measuring scale are respectively and electrically connected with the controller.
As a preferable structure of the utility model, the utility model further comprises a first bracket, wherein the first bracket is arranged on the first weight scale, the stirring barrel is arranged on the first bracket, the height of the stirring barrel is higher than that of the receiving barrel, and the liquid discharge pipeline is obliquely downwards arranged.
As a preferable structure of the utility model, the bottom of the stirring barrel is cone-shaped, the liquid discharge pipeline is arranged at the bottom of the stirring barrel, and the third electric ball valve is arranged close to the discharge port of the liquid discharge pipeline
As a preferable structure of the present utility model, the drain line is inclined downward at an angle of 45 °.
As a preferable structure of the utility model, one end of the solvent pipeline connected with the stirring barrel is arranged obliquely upwards, the end part of the solvent pipeline extends into the stirring barrel, and the end part of the solvent pipeline positioned in the stirring barrel is arranged obliquely downwards.
As a preferable structure of the utility model, the inclination angle of the end of the solvent pipeline connected with the stirring barrel is 60 degrees, the end of the solvent pipeline extends to 3cm in the stirring barrel, and the inclination downward angle of the end of the solvent pipeline positioned in the stirring barrel is 30 degrees.
As a preferable structure of the utility model, the wall of the stirring barrel is provided with an interlayer, a temperature control system is arranged in the interlayer, the temperature control system is electrically connected with a controller, and the inner wall of the stirring barrel is provided with a plurality of protruding baffles.
As a preferable structure of the utility model, a quick-release caliper is arranged on a solute pipeline which is communicated with the solute barrel and the stirring barrel.
As a preferable structure of the utility model, the solvent barrel and the stirring barrel are respectively provided with a cleaning liquid outlet.
Compared with the prior art, the beneficial effects achieved by the technical scheme are as follows:
Compared with the traditional manual preparation, the system greatly improves the efficiency, reduces the waste of medicaments and improves the safety in the preparation process; the system adopts a weight scale, a solvent pipeline is obliquely arranged, liquid level difference is utilized for discharging liquid, and a controller is automatically and fully automatically controlled, so that the dilution configuration of the liquid medicament can be more accurate; the method is applicable to the configuration of liquid medicaments with a plurality of types, and has wider applicability.
Drawings
FIG. 1 is a schematic diagram of an automated dilution configuration system for liquid medicament according to an embodiment;
FIG. 2 is a schematic diagram of a system for automatically diluting and configuring a liquid medicament according to a second embodiment;
FIG. 3 is a schematic diagram of an automated dilution configuration system for liquid medicament according to an embodiment;
FIG. 4 is a cross-sectional view of a mixing drum according to one embodiment;
Fig. 5 is a cross-sectional view of a second embodiment of the mixing drum.
Reference numerals illustrate:
1. A stirring barrel; 101. an interlayer; 102. a temperature control system; 103. a baffle; 104. a refrigerant inlet; 105. a refrigerant outlet; 106. a compressor; 2. a stirrer; 3. a solvent barrel; 301. a solvent line; 302. a solvent pump; 303. a first electrically operated ball valve; 4. a solute barrel; 401. a solute line; 402. a solute pump; 403. a second electric ball valve; 404. a quick release caliper; 501. a first weight scale; 502. a second weight scale; 503. a controller; 504. a first bracket; 6. receiving a charging basket; 601. a liquid discharge pipeline; 602. a third electric ball valve; 701. and a cleaning liquid discharge port.
Detailed Description
In order to describe the technical content, constructional features, achieved objects and effects of the technical solution in detail, the following description is made in connection with the specific embodiments in conjunction with the accompanying drawings.
As shown in fig. 1 to 3, the present embodiment provides an automated dilution configuration system for liquid medicines, including: 1 agitator, solvent bucket 3, solute bucket 4 and controller 503, agitator 1 communicate with solvent bucket 3 and solute bucket 4 respectively, be equipped with solvent pump 302 and first electronic ball valve 303 on the solvent pipeline 301 that solvent bucket 3 and agitator 1 communicate, be equipped with solute pump 402 and second electronic ball valve 403 on the solute pipeline 401 that solute bucket 4 and agitator 1 communicate, agitator 1 top is equipped with agitator 2, agitator 1 bottom is equipped with fluid-discharge line 601, and agitator 1 bottom is equipped with first weight scale 501, first electronic ball valve 303, second electronic ball valve 403, solvent pump 302, solute pump 402, agitator 2 and first weight scale 501 respectively with controller 503 electric connection.
In the specific implementation process of the embodiment, the solution preparation proportion is not monitored by adopting a traditional flowmeter, but the solution is prepared by adopting a method of respectively weighing the weight of the solvent and the solute, compared with the traditional preparation method, the solution is more accurate and can not touch the flowmeter regulating valve by mistake, and the opening of the first electric ball valve and the second electric ball valve is automatically regulated by the controller through the weight change of the first weighing scale, so that the opening of the valve is continuously reduced until the valve is thoroughly closed when the solution is near to the required quality, and the filling is more accurate and not wasted. The dispensing system of this embodiment can control the overall error to within 3 to 5 thousandths of a conventional dispensing system. In some embodiments, as shown in fig. 2, a quick-release caliper 404 is arranged on a solute pipe which is communicated with a stirring barrel, so that the solute barrel can be replaced at any time, and a dosing pump can be adopted for the solute pump, so that cross contamination is reduced, and meanwhile, compared with a traditional pump, the dosing pump is more corrosion-resistant and safer in acid-base tolerance.
As shown in fig. 1 and 3, in the present embodiment, the solvent tank and the stirring tank bottom are further provided with cleaning liquid discharge ports 701, respectively.
As shown in fig. 1, 2 and 3, in this embodiment, the system further includes a receiving bucket 6, a liquid discharge pipeline 601 disposed at the bottom of the stirring bucket 1 is communicated with the receiving bucket 6, a third electric ball valve 602 is disposed on the liquid discharge pipeline 601, a second weight scale 502 is disposed at the bottom of the receiving bucket 6, and the third electric ball valve 602 and the second weight scale 502 are respectively electrically connected with the controller 503. Specifically, the device further comprises a first bracket 504, the first bracket 504 is arranged on the first weight scale 501, the stirring barrel 1 is arranged on the first bracket 504, the height of the stirring barrel is higher than that of the receiving barrel, and the liquid discharge pipeline 601 is obliquely downwards arranged. In addition, the bottom of the stirring barrel is also provided with a conical shape, the liquid discharge pipeline 601 is arranged at the bottom of the stirring barrel, and the third electric ball valve 602 is arranged close to the discharge port of the liquid discharge pipeline 601. Namely, in the embodiment, the split charging system cancels the traditional solution pumping mode, and adopts the liquid level difference to access the solution; and set up the agitator bottom into the toper, drain line 601 sets up for slope 45 angle downwards for solution discharge in the bucket is more thorough, is difficult for causing the feed liquid loss, can thoroughly discharge solution in the agitator, and the third electric ball valve is very near the discharge port of drain line, and solution stops discharging immediately when having guaranteed that the third electric ball valve is closed.
As shown in fig. 1 and 2, in the present embodiment, the end of the solvent pipe connected to the stirring tank is disposed obliquely upward, the end of the solvent pipe extends into the stirring tank, and the end of the solvent pipe located in the stirring tank is disposed obliquely downward. Specifically, the inclination angle of the end, connected with the stirring barrel 1, of the solvent pipeline 301 may be 60 °, the end of the solvent pipeline 301 extending into the stirring barrel may be 3cm, and the inclination downward angle of the end of the solvent pipeline 301 located in the stirring barrel may be 30 °; thus, when the solvent is stopped to be added, the solvent does not remain in the pipeline to influence the preparation precision.
As shown in fig. 4 and 5, in the present embodiment, an interlayer 101 is disposed on a wall of the stirring barrel, a temperature control system 102 is disposed in the interlayer 101, the temperature control system 102 is electrically connected to a controller 503, and a plurality of protruding baffles 103 are disposed on an inner wall of the stirring barrel 1. In this embodiment, the temperature control system 102 has the functions of intelligent control of cooling and heating, and after the refrigerant is added through the pipeline in the interlayer, the compressor 106 is intelligently turned on to perform heating or cooling. The inner wall of agitator has inwards protruding baffle, and is simpler for traditional coil pipe heating washing inside, and heat transfer area is big, and temperature control efficiency is higher, and protruding baffle can accelerate stirring rate.
For a better explanation of the operation and working principle of the present system, the following is exemplified:
Before starting, the first electric ball valve, the second electric ball valve, the third electric ball valve and the cleaning fluid outlet are all closed, the quality and the washing time of the added washing water are set, and at the moment, the first electric ball valve is automatically opened to add the washing water into the stirring barrel; after the washing water reaches a designated liquid level, the stirrer automatically starts the inside of the washing stirring barrel, and after the preset time is reached, the cleaning liquid outlet is opened to discharge the washing water.
After washing, setting solution concentration to start liquid medicament automatic preparation, and installing a corresponding solute barrel according to the preparation requirement, wherein the solute barrel and the stirring barrel are connected by a quick-release buckle, so that the disassembly and the assembly are convenient; the controller controls the first electric ball valve to open and starts to add solvent pure water, and the controller monitors the first weighing scale in real time, and when the instruction reaches 237KG, the valve opening of the valve of the first electric ball valve which receives the controller signal slowly becomes smaller until the valve is thoroughly closed when the valve reaches 237.5KG, and meanwhile pure water in a solvent pipeline does not remain, so that the influence on the preparation precision is avoided. At this time, the first weight scale shows 237.5KG, the dosing pump starts the second electric ball valve to automatically open and add solute, when the controller detects that the weight of the first weight scale reaches 250.kg in real time, the valve opening of the second electric ball valve is controlled to be slowly reduced until the valve opening reaches 250.kg, and the valve is thoroughly closed, and the valve delay error is called as 250.2KG at this time. At this time, the stirrer switch was turned on to start stirring the solution.
In this embodiment, the solution is a scale inhibitor, and the temperature requirement is higher than 5 ℃, so as shown in fig. 4, pure water needs to be added from the refrigerant inlet 104, the refrigerant outlet 105 is discharged, the temperature control system is started after the addition is completed, and the temperature reaches the preparation requirement temperature through the compressor; after reaching the preset time, the stirrer is closed, and the solution starts to stand still at the moment; after reaching the preset standing time, the third electric ball valve is opened to receive and discharge the solution, the opening of the valve is gradually reduced while receiving and discharging, and when the mass of the second weighing scale reaches 24.9kg, the opening of the valve is enabled to be the minimum value; after the mass reaches 25.01kg, the valve is closed. The third electric ball valve is very close to the liquid outlet and cannot be influenced by the closing delay of the third electric ball valve;
When the last barrel is connected, the third electric ball valve is fully opened to utilize the liquid level, so that the solution in the stirring barrel can be completely discharged, and waste and environmental pollution during washing are avoided; thus, after the washing was completed, the 250KG solution of% 5 was prepared. In this embodiment, the overall error may be controlled between 3 and 5 thousandths. Then, the above washing steps are repeated to complete the washing.
It should be noted that, although the foregoing embodiments have been described herein, the scope of the present utility model is not limited thereby. Therefore, based on the innovative concepts of the present utility model, alterations and modifications to the embodiments described herein, or equivalent structures or equivalent flow transformations made by the present description and drawings, apply the above technical solution, directly or indirectly, to other relevant technical fields, all of which are included in the scope of the utility model.
Claims (10)
1. An automated liquid medicament dilution configuration system, comprising: the device comprises a stirring barrel, a solvent barrel, a solute barrel and a controller, wherein the stirring barrel is respectively communicated with the solvent barrel and the solute barrel, a solvent pump and a first electric ball valve are arranged on a solvent pipeline through which the solvent barrel is communicated with the stirring barrel, a solute pump and a second electric ball valve are arranged on a solute pipeline through which the solute barrel is communicated with the stirring barrel, a stirrer is arranged at the top of the stirring barrel, a liquid discharge pipeline is arranged at the bottom of the stirring barrel, and a first weight scale is arranged at the bottom of the stirring barrel, and the first electric ball valve, the second electric ball valve, the solvent pump, the solute pump, the stirrer and the first weight scale are respectively electrically connected with the controller.
2. The automated liquid medicament dilution configuration system of claim 1, wherein: the automatic weighing device is characterized by further comprising a receiving bucket, wherein a liquid discharge pipeline arranged at the bottom of the stirring bucket is communicated with the receiving bucket, a third electric ball valve is arranged on the liquid discharge pipeline, a second weighing scale is arranged at the bottom of the receiving bucket, and the third electric ball valve and the second weighing scale are respectively and electrically connected with the controller.
3. The automated liquid medicament dilution configuration system of claim 2, wherein: still include first support, first support is located on the first weight scale, the agitator is located on the first support, the height of agitator is higher than and connects the storage bucket height, the drain line slope sets up downwards.
4. The automated liquid medicament dilution configuration system of claim 3, wherein: the bottom of the stirring barrel is conical, the liquid discharge pipeline is arranged at the bottom of the stirring barrel, and the third electric ball valve is arranged close to the discharge port of the liquid discharge pipeline.
5. The automated liquid medicament dilution configuration system of claim 3, wherein: the drain line is inclined at a downward angle of 45 °.
6. The automated liquid medicament dilution configuration system of claim 1, wherein: the solvent pipeline is arranged obliquely upwards at one end connected with the stirring barrel, the end part of the solvent pipeline extends into the stirring barrel, and the end part of the solvent pipeline positioned in the stirring barrel is arranged obliquely downwards.
7. The automated liquid medicament dilution configuration system of claim 6, wherein: the inclination angle of one end of the solvent pipeline connected with the stirring barrel is 60 degrees, the end part of the solvent pipeline extends to 3cm in the stirring barrel, and the inclination downward angle of the end part of the solvent pipeline positioned in the stirring barrel is 30 degrees.
8. The automated liquid medicament dilution configuration system of claim 1, wherein: the stirring barrel is characterized in that an interlayer is arranged on the barrel wall of the stirring barrel, a temperature control system is arranged in the interlayer, the temperature control system is electrically connected with the controller, and a plurality of protruding baffles are arranged on the inner wall of the stirring barrel.
9. The automated liquid medicament dilution configuration system of claim 1, wherein: and a quick-release caliper is arranged on a solute pipeline which is communicated with the solute barrel and the stirring barrel.
10. The automated liquid medicament dilution configuration system of claim 1, wherein: the bottoms of the solvent barrel and the stirring barrel are respectively provided with a cleaning liquid discharge outlet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202323572597.0U CN221432691U (en) | 2023-12-27 | 2023-12-27 | Automatic dilution configuration system for liquid medicament |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202323572597.0U CN221432691U (en) | 2023-12-27 | 2023-12-27 | Automatic dilution configuration system for liquid medicament |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN221432691U true CN221432691U (en) | 2024-07-30 |
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ID=92063966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202323572597.0U Active CN221432691U (en) | 2023-12-27 | 2023-12-27 | Automatic dilution configuration system for liquid medicament |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN221432691U (en) |
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2023
- 2023-12-27 CN CN202323572597.0U patent/CN221432691U/en active Active
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