CN221224538U

CN221224538U - Colloidal gold high flux detects auxiliary device

Info

Publication number: CN221224538U
Application number: CN202322607864.7U
Authority: CN
Inventors: 闻瑞琪; 周鑫; 曲彬; 张建雄
Original assignee: Beijing Kede North Technology Co ltd
Current assignee: Beijing Kede North Technology Co ltd
Filing date: 2023-09-25
Publication date: 2024-06-25
Anticipated expiration: 2033-09-25

Abstract

The utility model discloses a colloidal gold high-flux detection auxiliary device, which comprises: the detection layer is located the liquid adding layer that detection layer top and adoption transparent material made, connect the detection layer with the liquid adding layer is used for adjusting liquid adding layer with detect high adjustment mechanism between the layer, and be used for adding a plurality of liquid filling machines that detect liquid, wherein the detection layer is provided with a plurality of holding tanks that are used for transversely placing the colloidal gold test paper side by side along its length, be provided with the liquid feeding hole corresponding to the liquid feeding district of every holding tank front end on the liquid adding layer, every the liquid feeding hole corresponds to a liquid filling machine.

Description

Colloidal gold high flux detects auxiliary device

Technical Field

The utility model relates to the technical field of biological detection, in particular to a colloidal gold high-flux detection auxiliary device.

Background

The colloidal gold immunochromatography can rapidly detect pesticide residues, and in the use process, the requirement of multiple detection is often existed. When the conventional method solves this problem, there are often two methods.

One method is to set up multiple detection lines on a single test strip to realize multiple detection. However, 5-fold detection on a single test strip is the most commercially available at present because of portability and limitation of test strip type, and the requirement is difficult to meet.

Another method is to use multiple test strips to perform the detection simultaneously. CN201993317U discloses a multichannel synchronous rapid detection box, comprising a box body and a test strip, wherein the box body comprises a base and a panel, the base is provided with a fixing groove for installing the test strip, the panel is provided with a sample adding hole and a result display window, and the sample adding hole is connected with a sample cavity; the test strip comprises a plurality of fixing grooves, wherein one end of each fixing groove is provided with a test strip through hole, and the caliber of each through hole is matched with the width and the thickness of the test strip; the sample pad of the test strip head is communicated with the sample cavity through the respective test strip through hole. The number of the fixing grooves is 3-5, and the test strips are exposed out of the fixing grooves. During operation, sample is added through the sample adding hole to fill the inside sample cavity, and then the sample is sucked into the test paper sample pad through capillary action and sequentially migrates to the gold label binding pad and the reaction membrane through the siphon principle, so that multi-index joint inspection of the sample is realized.

However, this is only suitable for small amounts of detection, and the sample chamber is enlarged for high throughput detection, and a large amount of waste is caused by sharing one sample chamber between a plurality of fixing grooves. Secondly, for pesticide residue detection, a sample to be detected is generally directly dripped on a test paper detection area, and the amount added each time is fixed, so that in order to ensure detection accuracy without waste, the dripping direction needs to be ensured to be positioned right above a colloidal gold test paper reaction area.

Disclosure of utility model

The utility model aims to provide a colloidal gold high-flux detection auxiliary device, which partially solves or alleviates the defects in the prior art and can more accurately realize vertical dripping of a sample to be detected.

In order to solve the technical problems, the utility model adopts the following technical scheme:

a colloidal gold high throughput detection aid, comprising: the detection layer is located the liquid adding layer that detection layer top and adoption transparent material made, connect the detection layer with the liquid adding layer is used for adjusting liquid adding layer with detect high adjustment mechanism between the layer, and be used for adding a plurality of liquid adding machines that detect liquid, wherein, the detection layer is provided with a plurality of holding tanks that are used for transversely placing the colloidal gold test paper side by side along its length, the liquid adding area that corresponds every holding tank front end on the liquid adding layer is provided with the liquid feeding hole, every the liquid adding machine corresponds a liquid feeding hole.

Further, the adjusting mechanism of the colloidal gold high-flux detection auxiliary device comprises a substrate, the bottom end of the substrate is connected with the detection layer, and a plurality of positioning holes are formed in the two sides of the substrate at intervals along the height direction of the substrate; the adjusting structure further comprises at least two positioning pins matched with the positioning holes.

Further, the liquid adding layer comprises a plate-shaped body, and liquid adding holes are formed in the plate-shaped body corresponding to the liquid adding areas at the front end of each accommodating groove; the upper surface of one side of the platy body far away from the liquid adding hole is provided with a positioning flank which can be attached to the outer side surface of the substrate, and two sides of the positioning flank are respectively provided with a matching hole; when the matching hole and the positioning hole are locked by the positioning pin, the liquid adding layer is fixed on the plate-shaped body.

Further, the lower surface of the liquid adding layer far away from one side of the liquid adding hole is provided with a reinforcing flank which can be attached to the inner side surface of the substrate.

Further, the number of the positioning holes is three.

Further, the liquid filler adopts a syringe or a pipette.

Further, the colloidal gold high-throughput detection auxiliary device further comprises: the elastic positioning plug can be in sliding connection with the tube body of the liquid filling device, and comprises the tube body and a baffle plate arranged at the bottom of the tube body.

Further, the inner diameter of the tube body is smaller than the outer diameter of the tube body of the liquid charger.

Further, the baffle plate extends from the bottom of the pipe body along the direction vertical to the axial direction of the pipe body; or the baffle is in a horn shape.

Further, the number of the liquid adding holes is 12, and the number of the positioning grooves is 12.

The beneficial effects are that: according to the utility model, the detection layer is arranged, the liquid adding layer is arranged above the detection layer, and the liquid adding hole which is opposite to the colloidal gold test paper reaction area is arranged on the liquid adding layer, so that the liquid adding height (namely the height between the liquid adding layer and the detection layer) and the direction (namely the vertical dripping on the horizontally arranged colloidal gold test paper) can be directly realized through the liquid adding hole (namely the height between the liquid adding layer and the detection layer), the detection operation standard is more met, the operation is simpler, the problem that the sample to be detected is wasted or the detection is inaccurate due to inaccurate grasp of the height and the direction during manual dripping is avoided, and the liquid adding layer made of transparent materials can be directly used for observation after the reaction, so that an observation window is not required to be additionally arranged.

Secondly, adjust the height between the two-layer through setting up adjustment mechanism between the two-layer to still set up can with the liquid feeding stopper of liquid feeder matched with, thereby make even under the certain circumstances of height between the two-layer, also accessible adjusts the liquid feeder and compare the height between the liquid feeding layer, thereby adjust the height between the play liquid hole of liquid feeder and the test paper reaction zone, and then realize the different detection of different drop heights and go on simultaneously.

Drawings

In order to more clearly illustrate the embodiments of the present utility model or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below. Like elements or portions are generally identified by like reference numerals throughout the several figures. In the drawings, elements or portions thereof are not necessarily drawn to scale. It will be apparent to those of ordinary skill in the art that the drawings in the following description are of some embodiments of the utility model and that other drawings may be derived from these drawings without inventive faculty.

FIG. 1 is a schematic diagram of a colloidal gold high-throughput detection auxiliary device according to an exemplary embodiment of the utility model;

FIG. 2 is an exploded view of a colloidal gold high throughput detection aid in accordance with an exemplary embodiment of the present utility model;

FIG. 3 is a schematic view showing the positioning of a liquid-adding layer in a colloidal gold high-throughput detection auxiliary device according to an exemplary embodiment of the utility model by positioning holes and positioning pins;

Fig. 4 is a schematic diagram showing that the liquid adding layer is at the lowest position in the colloidal gold high throughput detection auxiliary device according to an exemplary embodiment of the utility model.

Reference numerals: 11 liquid adding layers, 110 liquid adding holes, 111 reinforcing flanks, 112 positioning flanks and 113 matching holes; 12 detection layer 121 accommodation groove; 13 adjusting mechanism, 131 locating hole, 132 locating pin; 14 a liquid filler; 15 resiliently positioning the plug.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present utility model more clear, the technical solutions of the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model. It will be apparent that the described embodiments are some, but not all, embodiments of the utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

In this document, suffixes such as "module", "component", or "unit" used to represent elements are used only for facilitating the description of the present utility model, and have no particular meaning in themselves. Thus, "module," "component," or "unit" may be used in combination. The terms "upper," "lower," "inner," "outer," "front," "rear," "one end," "the other end," and the like herein refer to an orientation or positional relationship based on that shown in the drawings, merely for convenience of description and to simplify the description, and do not denote or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the utility model. Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying relative importance. The terms "mounted," "configured to," "connected," and the like, herein, are to be construed broadly as, for example, "connected," whether fixedly, detachably, or integrally connected, unless otherwise specifically defined and limited; the two components can be mechanically connected, can be directly connected or can be indirectly connected through an intermediate medium, and can be communicated with each other. The specific meaning of the above terms in the present utility model will be understood in specific cases by those of ordinary skill in the art. Herein, "and/or" includes any and all combinations of one or more of the associated listed items. Herein, "plurality" means two or more, i.e., it includes two, three, four, five, etc.

Referring to fig. 1 to 4, the colloidal gold high-throughput detection auxiliary device of the present utility model includes: the detection layer 12 is located detection layer 12 top and adopts the liquid adding layer 11 that transparent material was made, connects detection layer 12 and liquid adding layer 11 and is used for adjusting the adjustment mechanism who adds the height between liquid layer and the detection layer to and be used for adding a plurality of liquid filling machines that detect liquid.

In some embodiments, the detection layer 11 is provided with a plurality of accommodating grooves 121 for laterally placing the colloidal gold test paper along the length thereof, and the liquid adding areas on the liquid adding layer 11 corresponding to the front end of each accommodating groove 121 are provided with liquid adding holes 110, and each liquid adding hole 110 corresponds to each liquid charger 14.

In some embodiments, the adjusting mechanism includes a substrate with a bottom end connected to the detecting layer 12, and a plurality of positioning holes 131 are disposed on two sides of the substrate at intervals along a height direction of the substrate; the adjustment structure further includes at least two alignment pins 132 that mate with the alignment holes.

In some embodiments, the liquid adding layer 11 includes a plate-shaped body provided with liquid adding holes 110 corresponding to the liquid adding areas at the front end of each of the receiving grooves 121; the upper surface of the plate-shaped body, which is far away from the liquid adding hole, is provided with a positioning flank 112 which can be attached to the outer side surface of the substrate, and two sides of the positioning flank 112 are respectively provided with a matching hole 113; when the fitting hole 113 and the positioning hole 131 are locked by the positioning pin 132, the charging layer is fixed to the plate-like body.

Preferably, three positioning holes are arranged on the plate-shaped body at intervals along the height direction (or the vertical direction in the figure) of the plate-shaped body, so that the height between the liquid adding layer and the detection layer can be adjusted according to actual needs.

In some embodiments, the lower surface of the side of the charging layer away from the charging hole is provided with a reinforcing flank 111 that can be attached to the inner side of the substrate.

In some embodiments, the liquid adding device adopts a syringe or a liquid transferring gun or a dropper, and a scale is arranged on the tube body, so that quantitative dripping can be realized according to the scale.

In some embodiments, the colloidal gold high-throughput detection assisting device further comprises: the positioning plug 15 comprises an elastic tube body and a baffle plate arranged at the bottom of the tube body.

Preferably, the inner diameter of the filling hole is larger than the outer diameter of the filler tube, and the inner diameter of the positioning plug tube is smaller than the outer diameter of the filler tube, so that the filler tube can be tightly attached to the filler tube when it is inserted through the filler tube.

In some embodiments, the baffle extends from the bottom of the tube body along the direction perpendicular to the axial direction of the tube body, i.e. the baffle is arranged in a plane, so that when the liquid charger is placed on the liquid charging hole, the vertical dripping direction between the liquid charger and the detection layer is ensured through the cooperation between the baffle of the positioning plug and the upper surface of the liquid charging layer.

Of course, further, the baffle plate can be in a horn shape, so that the baffle plate can be adsorbed on the upper surface of the liquid adding layer, and the stability is improved.

Preferably, in order to facilitate processing and realize high-throughput detection, the number of liquid adding holes on the liquid adding layer is 12, and correspondingly, the number of positioning grooves on the detection layer is 12.

It should be noted that, in this document, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.

The embodiments of the present utility model have been described above with reference to the accompanying drawings, but the present utility model is not limited to the above-described embodiments, which are merely illustrative and not restrictive, and many forms may be made by those having ordinary skill in the art without departing from the spirit of the present utility model and the scope of the claims, which are to be protected by the present utility model.

Claims

1. The utility model provides a high flux detection auxiliary device of colloidal gold which characterized in that includes: the detection layer is positioned above the detection layer and is made of transparent material, the detection layer is connected with the liquid adding layer, the regulating mechanism is used for regulating the height between the liquid adding layer and the detection layer, and a plurality of liquid adding devices are used for adding detection liquid,

The detection layer is provided with a plurality of accommodating grooves for transversely placing the colloidal gold test paper along the length of the detection layer in parallel, the liquid adding layer is provided with liquid adding holes corresponding to the liquid adding areas at the front ends of the accommodating grooves, and each liquid adding hole corresponds to one liquid charger.

2. The colloidal gold high-flux detection auxiliary device according to claim 1, wherein the adjusting mechanism comprises a substrate, the bottom end of which is connected with the detection layer, and a plurality of positioning holes are formed on two sides of the substrate at intervals along the height direction of the substrate; the adjusting mechanism further comprises at least two positioning pins matched with the positioning holes.

3. The colloidal gold high-throughput detection auxiliary device according to claim 2, wherein the liquid adding layer comprises a plate-shaped body, and the plate-shaped body is provided with liquid adding holes corresponding to the liquid adding areas at the front end of each accommodating groove; the upper surface of one side of the platy body far away from the liquid adding hole is provided with a positioning flank which can be attached to the outer side surface of the substrate, and two sides of the positioning flank are respectively provided with a matching hole; when the matching hole and the positioning hole are locked by the positioning pin, the liquid adding layer is fixed on the plate-shaped body.

4. The colloidal gold high-throughput detection auxiliary device according to claim 3, wherein a reinforcing flank which can be attached to the inner side surface of the substrate is arranged on the lower surface of the liquid adding layer on the side far away from the liquid adding hole.

5. The colloidal gold high-throughput detection auxiliary device according to claim 2, wherein the number of the positioning holes is three.

6. The colloidal gold high-throughput detection auxiliary device according to claim 1, wherein the liquid filler is a syringe or a pipette.

7. The colloidal gold high throughput detection auxiliary device according to claim 6, further comprising: the elastic positioning plug can be in sliding connection with the tube body of the liquid filling device, and comprises the tube body and a baffle plate arranged at the bottom of the tube body.

8. The colloidal gold high flux detection aid according to claim 7, wherein an inner diameter of the tube is smaller than an outer diameter of the tube of the liquid filler.

9. The colloidal gold high-flux detection auxiliary device according to claim 7, wherein the baffle plate is formed by extending from the bottom of the tube body along a direction perpendicular to the axial direction of the tube body; or the baffle is in a horn shape.

10. The colloidal gold high-throughput detection auxiliary device according to any one of claims 1 to 9, wherein the number of the liquid adding holes is 12, and the number of the accommodating grooves is 12.