CN221050345U - Reagent fixing mechanism of gene detection kit - Google Patents

Reagent fixing mechanism of gene detection kit Download PDF

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Publication number
CN221050345U
CN221050345U CN202322903925.4U CN202322903925U CN221050345U CN 221050345 U CN221050345 U CN 221050345U CN 202322903925 U CN202322903925 U CN 202322903925U CN 221050345 U CN221050345 U CN 221050345U
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China
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reagent
fixedly connected
plates
clamping plates
placing plate
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CN202322903925.4U
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Chinese (zh)
Inventor
张晗喆
李萌萌
阴凯丽
郝娜
蒋宇林
王亚茹
王文利
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Peking Union Medical College Hospital Chinese Academy of Medical Sciences
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Peking Union Medical College Hospital Chinese Academy of Medical Sciences
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Abstract

The utility model relates to a reagent fixing mechanism of a gene detection kit, and relates to the technical field of medical auxiliary equipment. The kit comprises a kit, wherein a cover is hinged to the upper end of the kit, a first reagent placing plate is fixedly connected between the side walls of the cover, a second reagent placing plate is slidably arranged between the side walls of the kit, a plurality of first reagent tube grooves and second reagent tube grooves are respectively formed in the upper ends of the first reagent placing plate and the kit, a plurality of first clamping plates and a plurality of second clamping plates are slidably arranged in the upper ends of the second reagent placing plates, a plurality of connecting plates are fixedly connected to the upper ends of the second reagent placing plates, and the first reagent placing plate, the second reagent placing plate, the first reagent tube grooves, the first clamping plates, the second clamping plates, the connecting plates and the first springs are matched to clamp reagent tubes inserted into the first reagent tube grooves and the first reagent placing plates so as to prevent the reagent tubes from shaking when the kit moves.

Description

Reagent fixing mechanism of gene detection kit
Technical Field
The utility model relates to the technical field of medical auxiliary equipment, in particular to a reagent fixing mechanism of a gene detection kit.
Background
With advances in technology, we have found that the occurrence of many genetic diseases is associated with complex structural variations in the genome. The technology utilizes a single DNA molecular genome restriction enzyme map to quickly generate a high-resolution and ordered whole genome restriction enzyme map through a novel high-resolution cytogenetic analysis technology, and has great application value in the aspect of detecting genome structural variation.
Similar products in the market at present mainly detect general structural variations, such as deletion, repetition and the like of genome fragments. However, the occurrence of some genetic diseases can be associated with complex structural variations. For example, a occult balanced chromosomal rearrangement (Balanced Chromosomal Rearrangements, BCRs) has profound effects on the development of a variety of human genetic diseases, and the BCRs variant carries an abnormally elevated risk of a couple to miscarriage or childbearing deficiency. The existing technology has very difficult detection of large fragment concealment BCRs. The technology fills the gap of detection in the market, and is very valuable in detecting complex structural variations such as large-fragment concealment balanced chromosome rearrangement and the like.
A gene detection kit with the bulletin number of CN205662525U relates to a gene detection kit. The utility model aims to solve the problems of single function and inconvenient use of the existing gene detection box. A gene detection kit comprises a box body, a glass plugboard, a magnifier plugboard, a centrifuge tube slot, a label sticker, a color chart, a magnetic fastening piece, a box cover, a first sponge cushion, a folding connecting piece, an incubator, a second sponge cushion, an ice bag, a brace and a camera bellows. However, in the process of storing and transferring the gene reagent, the reagent tube in the reagent storage box shakes along with the movement of the reagent storage box, and the reagent tube is easy to damage when being collided or extruded in the movement process.
Disclosure of utility model
According to the defects existing in the prior art, the utility model aims to provide a reagent fixing mechanism of a gene detection kit, which has the effects of limiting a reagent tube and preventing damage caused by collision or extrusion in the moving process.
The technical aim of the utility model is realized by the following technical scheme:
The utility model provides a reagent fixed establishment of gene detection kit, includes the kit, the upper end hinge of kit has the lid, the board is placed to the first reagent of fixedly connected with between the lateral wall of lid, the board is placed to the second reagent of sliding between the lateral wall of kit, a plurality of first reagent tube grooves and second reagent tube grooves have been seted up respectively to the upper end of first reagent placement board and kit, the upper end sliding of board is placed to the second reagent is provided with a plurality of first grip blocks and a plurality of second grip blocks, the upper end fixedly connected with of second reagent placement board a plurality of connecting plates, a plurality of the equal fixedly connected with in both sides of connecting plate two first springs, a plurality of the opposite side of first spring respectively with a plurality of second grip blocks and a plurality of first grip blocks are fixed, the upper end fixedly connected with two fixed plates of second reagent placement board, two the second spring is near side all fixedly connected with the second grip block respectively, four the second spring is connected with the second grip block and is located a plurality of second grip blocks of limit position adjustment mechanism on a plurality of second grip blocks, a plurality of first grip blocks are all connected with a plurality of second grip blocks.
Through adopting above-mentioned technical scheme, board, second reagent place board, first reagent tube groove, first grip block, second grip block, connecting plate, first spring cooperation can carry out the centre gripping to the reagent pipe of inserting in first reagent tube groove and the first reagent place the board, prevent that the reagent pipe from taking place to rock when the kit removes.
The present utility model may be further configured in a preferred example to: each group of adjusting mechanism comprises an adjusting groove, a long block, a short block and a first motor, wherein the adjusting groove is formed in one side of the second clamping plate, the inner top wall of the long block is rotationally connected with the long block, the lower end of the second reagent placing plate is fixedly connected with the first motor, and the output end of the first motor movably penetrates through the upper end of the second reagent placing plate and is fixed with the lower end of the long block.
Through adopting above-mentioned technical scheme, adjustment mechanism adjusts the distance between a plurality of second grip blocks and a plurality of first grip blocks.
The present utility model may be further configured in a preferred example to: the lifting mechanisms are arranged on two sides of the second reagent placing plate, each lifting mechanism comprises a pulling groove, a pulling rope and a moving block, the pulling grooves are formed in one side wall of the reagent box, the moving blocks are fixedly connected to one side of the second reagent placing plate, the moving blocks are slidably connected in the pulling grooves, the pulling rope is fixedly connected to the upper ends of the moving blocks, and the pulling rope movably penetrates through the upper ends of the reagent box and is fixed to the lower ends of the covers.
Through adopting above-mentioned technical scheme, elevating system can drive the second reagent and place the board and upwards slide when the lid is opened, conveniently takes out the reagent pipe.
The present utility model may be further configured in a preferred example to: two round bars are fixedly connected between the inner top wall and the inner bottom wall of the pulling groove, and the moving block is slidably connected to the circumferential sides of the two round bars.
Through adopting above-mentioned technical scheme, movable block and round bar sliding fit can improve the removal stability of movable block.
The present utility model may be further configured in a preferred example to: two fixedly connected with two gag levers between the fixed plate, a plurality of second grip block and first grip block all sliding connection are in the circumference side of two gag levers.
Through adopting above-mentioned technical scheme, the gag lever post can improve the mobility stability of second grip block and first grip block.
The present utility model may be further configured in a preferred example to: the two near sides of the fixed plate are respectively provided with a rotating block, the lower ends of the second reagent placing plates are fixedly connected with two second motors, and the output ends of the two second motors movably penetrate through the upper ends of the second reagent placing plates and are respectively fixed with the two rotating blocks.
Through adopting above-mentioned technical scheme, the second grip block and the first grip block of movable side are close to the reagent pipe to the movable block.
The present utility model may be further configured in a preferred example to: two groups of limiting mechanisms are arranged on two sides of the second reagent placing plate, each group of limiting mechanisms comprises a rectangular groove, a sliding rod and a sliding block, the rectangular groove is formed in one side wall of the reagent box, the sliding rod is fixedly connected between the inner top wall and the inner bottom wall of the rectangular groove, the sliding blocks are connected with the circumferential side sliding of the sliding rod, and the sliding blocks are fixedly connected to one side of the second reagent placing plate.
By adopting the technical scheme, the limiting mechanism can improve the movement stability of the second reagent placing plate.
In summary, the present utility model includes at least one of the following beneficial technical effects:
1. be provided with first reagent and place board, the board is placed to second reagent, first reagent tube chute, first grip block, the second grip block, the connecting plate, first spring, insert first reagent tube chute and first reagent place the inboard back, start first motor, the output of first motor drives the length piece and rotates, the longer weak point in adjustment tank promotes second grip block and first grip block and is close to the test tube, first spring is in compressed state, make first grip block and second grip block hold the test tube, can carry out the centre gripping to the reagent pipe of inserting in first reagent tube chute and the first reagent place the inboard, prevent that the reagent pipe from taking place to rock when the kit removes, produce collision or extrusion damage appears.
2. Be provided with stop gear and elevating system, when needs take out reagent, open the lid, the lid is through haulage rope pulling movable block and second reagent placing plate upwards slide, and the second reagent placing plate drives the test tube and upwards moves, can conveniently upwards promote the test tube one section, makes things convenient for the staff to take the reagent pipe.
Drawings
Fig. 1 is a perspective view of the present embodiment;
fig. 2 is a first perspective sectional view of the present embodiment;
fig. 3 is a partial enlarged view at a in fig. 2 of the present embodiment;
fig. 4 is a second perspective sectional view of the present embodiment;
Fig. 5 is a partial enlarged view at B in fig. 4 of the present embodiment.
In the figure, 1, a kit; 2. a cover; 3. a first reagent placement plate; 4. a lifting mechanism; 401. pulling the groove; 402. a traction rope; 403. a round bar; 404. a moving block; 5. a first reagent tube well; 6. a limit pad; 7. a second reagent placement plate; 8. an adjusting mechanism; 801. an adjustment tank; 802. a long block and a short block; 803. a first motor; 9. a first clamping plate; 10. a second clamping plate; 11. a fixing plate; 12. a first spring; 13. a second reagent tube well; 14. a limit rod; 15. a limiting mechanism; 1501. rectangular grooves; 1502. a slide bar; 1503. a slide block; 16. a second motor; 17. a connecting plate; 18. a second spring; 19. and rotating the block.
Detailed Description
The present utility model will be described in further detail with reference to the accompanying drawings.
Examples:
Referring to fig. 1-5, the reagent fixing mechanism of the gene detection reagent kit disclosed by the utility model comprises a reagent kit 1, a cover 2 is hinged at the upper end of the reagent kit 1, a first reagent placing plate 3 is fixedly connected between the side walls of the cover 2, a second reagent placing plate 7 is slidably arranged between the side walls of the reagent kit 1, a plurality of first reagent tube grooves 5 and second reagent tube grooves 13 are respectively arranged at the upper ends of the first reagent placing plate 3 and the reagent kit 1, a plurality of first clamping plates 9 and a plurality of second clamping plates 10 are slidably arranged at the upper ends of the second reagent placing plate 7, a first adjusting mechanism 8 and a first clamping plate 9 are preferably arranged at two sides of a notch of a second reagent tube groove 13 in the same row, a plurality of connecting plates 17 are fixedly connected at the upper ends of the second reagent placing plate 7, a first connecting plate 8 and a first connecting plate 9 are preferably arranged between the first adjusting mechanism 8 and the first clamping plate 9, two first springs 12 are preferably arranged at two sides of the first connecting plate 17 and are fixedly connected with two first springs 12, a plurality of first springs 12 positioned on the same connecting plate 17 are preferably arranged at one side of the first connecting plate 12 and two sides of the first connecting plate 12 and a plurality of first spring plates 12 and a second spring 12 are preferably arranged at one side of the second connecting plate 18 and are preferably connected with the second clamping plates 18 and are preferably at two sides of the second connecting plates 18 and are preferably arranged at two sides of the second connecting plate 18 and are preferably opposite sides of the second connecting plate 18 and are fixedly connected with the first connecting plate 12 and the first connecting plate 18, the first connecting plate 17 is preferably arranged at the second connecting plate 7 is preferably side 12 and a connecting plate 17 is fixedly to a connecting plate 12 is capable of a connecting plate 12, the circumference lateral wall of a plurality of first reagent tube grooves 5 is equal fixedly connected with spacing pad 6, the inner circle of the spacing pad 6 of preferred is the cockscomb structure, all be provided with adjustment mechanism 8 on a plurality of second grip blocks 10 in order to realize the regulation of a plurality of second grip blocks 10 and a plurality of first grip blocks 9, every adjustment mechanism 8 of group all includes adjustment tank 801, length piece 802 and first motor 803, one side in second grip block 10 is seted up to the adjustment tank 801, the interior roof rotation of length piece 802 is connected with length piece 802, the lower extreme fixedly connected with first motor 803 of second reagent place plate 7, and the output activity of first motor 803 runs through the upper end of second reagent place plate 7 and is fixed with the lower extreme of length piece 802, insert reagent in first reagent tube groove 5 and the first reagent place plate 3 back, start first motor 803, the output of first motor drives length piece 802 and rotates, the longer tip in both sides of preferred length piece 802, the longer length of adjustment tank 801 promotes second grip plate 10 and first grip plate 9 to be close to, first spring 12 makes first spring 10 and first tube insert 5, reagent box 10 and first tube insert 3, reagent box clamp 10 and reagent box in the time of test tube 1 is prevented to be rocked.
The both sides of board 7 are placed to second reagent all are provided with climbing mechanism 4, every elevating system 4 of group all includes pulling groove 401, haulage rope 402 and movable block 404, pulling groove 401 is seted up in a lateral wall of kit 1, movable block 404 fixed connection is in one side of board 7 is placed to the second reagent, movable block 404 sliding connection is in pulling groove 401, haulage rope 402 fixed connection is in the upper end of movable block 404, and haulage rope 402 activity runs through the upper end of kit 1 and is fixed with the lower extreme of lid 2, fixedly connected with two round bars 403 between the interior roof of pulling groove 401 and the interior bottom wall, movable block 404 sliding connection is in the circumference side of two round bars 403, movable block 404 and round bar 403 sliding fit can improve the mobility stability of movable block 404, when needs take out reagent, open lid 2, lid 2 is placed board 7 through haulage rope 402 pulling movable block 404 and second reagent, second reagent is placed board 7 and is driven the test tube and is upwards moved, can conveniently upwards promote one section, make things convenient for the staff to take the reagent tube.
Two gag lever posts 14 are fixedly connected between two fixed plates 11, a plurality of second clamping plates 10 and first clamping plates 9 are all in sliding connection with the circumferential sides of two gag lever posts 14, and the movement stability of the second clamping plates 10 and the first clamping plates 9 can be improved by the gag lever posts 14.
The two fixed plates 11 are provided with rotating blocks 19 near the sides, the preferred rotating blocks 19 are provided with one longer end, the lower ends of the second reagent placing plates 7 are fixedly connected with two second motors 16, because one second clamping plate 10 and one first clamping plate 9 at the side cannot move, the second springs 18, the rotating blocks 19 and the second motors 16 are arranged, and the output ends of the two second motors 16 movably penetrate through the upper ends of the second reagent placing plates 7 and are respectively fixed with the two rotating blocks 19, and the rotating blocks 19 can drive the second clamping plates 10 and the first clamping plates 9 at the side to move towards the reagent tubes to approach.
Two groups of limiting mechanisms 15 are arranged on two sides of the second reagent placement plate 7, each group of limiting mechanisms 15 comprises a rectangular groove 1501, a sliding rod 1502 and a sliding block 1503, the rectangular groove 1501 is formed in one side wall of the reagent kit 1, the sliding rod 1502 is fixedly connected between the inner top wall and the inner bottom wall of the rectangular groove 1501, the sliding block 1503 is connected with the sliding block 1503 in a sliding manner in the circumferential direction of the sliding rod 1502, the sliding block 1503 is fixedly connected to one side of the second reagent placement plate 7, and the limiting mechanisms 15 can improve the movement stability of the second reagent placement plate 7.
The implementation principle of the embodiment is as follows: after the reagent is inserted into the first reagent tube groove 5 and the first reagent placing plate 3, the first motor 803 is started, the output end of the first motor 803 drives the long and short block 802 to rotate, the long and short regulating groove 801 pushes the second clamping plate 10 and the first clamping plate 9 to approach the test tube, the first spring 12 is in a compressed state, so that the first clamping plate 9 and the second clamping plate 10 clamp the test tube, and the reagent tube inserted into the first reagent tube groove 5 and the first reagent placing plate 3 can be clamped, so that the reagent tube is prevented from shaking when the reagent box 1 moves.
What is not described in detail in this specification is prior art known to those skilled in the art.
The embodiments of the present utility model are all preferred embodiments of the present utility model, and are not intended to limit the scope of the present utility model in this way, therefore: all equivalent changes in structure, shape and principle of the utility model should be covered in the scope of protection of the utility model.

Claims (7)

1. The utility model provides a reagent fixed establishment of gene detection kit, includes kit (1), its characterized in that: the upper end of the reagent box (1) is hinged with a cover (2), a first reagent placing plate (3) is fixedly connected between the side walls of the cover (2), a second reagent placing plate (7) is slidably arranged between the side walls of the reagent box (1), a plurality of first reagent tube grooves (5) and second reagent tube grooves (13) are respectively formed in the upper ends of the first reagent placing plate (3) and the reagent box (1), a plurality of first clamping plates (9) and a plurality of second clamping plates (10) are slidably arranged in the upper ends of the second reagent placing plate (7), a plurality of connecting plates (17) are fixedly connected to the upper ends of the second reagent placing plate (7), two first springs (12) are fixedly connected to the two sides of the connecting plates (17), the other sides of the first springs (12) are respectively fixed with a plurality of second clamping plates (10) and a plurality of first clamping plates (9), two fixing plates (11) are fixedly connected to the upper ends of the second reagent placing plate (7), two fixing plates (11) are fixedly connected to the two side of the second clamping plates (18) and are respectively connected to the side of the second clamping plates (18) by the first springs (6), and the plurality of second clamping plates (10) are provided with adjusting mechanisms (8) so as to realize the adjustment of the plurality of second clamping plates (10) and the plurality of first clamping plates (9).
2. The reagent fixing mechanism for a gene assaying kit according to claim 1, wherein: every group adjustment mechanism (8) all include adjustment tank (801), length piece (802) and first motor (803), one side of second grip block (10) is seted up in adjustment tank (801), the interior roof rotation of length piece (802) is connected with length piece (802), the lower extreme fixedly connected with first motor (803) of board (7) is placed to second reagent, and the output activity of first motor (803) runs through the upper end of board (7) is placed to second reagent and is fixed with the lower extreme of length piece (802).
3. The reagent fixing mechanism for a gene assaying kit according to claim 1, wherein: the both sides of board (7) are placed to second reagent all are provided with elevating system (4), every group elevating system (4) all include pulling groove (401), haulage rope (402) and movable block (404), pulling groove (401) are seted up in a lateral wall of kit (1), movable block (404) fixed connection is in one side of board (7) is placed to the second reagent, movable block (404) sliding connection is in pulling groove (401), haulage rope (402) fixed connection is in the upper end of movable block (404), and haulage rope (402) activity runs through the upper end of kit (1) and is fixed with the lower extreme of lid (2).
4. A reagent fixing mechanism for a gene assaying kit according to claim 3, wherein: two round bars (403) are fixedly connected between the inner top wall and the inner bottom wall of the pulling groove (401), and the moving block (404) is connected to the circumferential sides of the two round bars (403) in a sliding mode.
5. The reagent fixing mechanism for a gene assaying kit according to claim 1, wherein: two limiting rods (14) are fixedly connected between the two fixing plates (11), and the second clamping plates (10) and the first clamping plates (9) are both in sliding connection with the circumferential sides of the two limiting rods (14).
6. The reagent fixing mechanism for a gene assaying kit according to claim 1, wherein: the two near sides of the fixed plates (11) are respectively provided with a rotating block (19), the lower ends of the second reagent placing plates (7) are fixedly connected with two second motors (16), and the output ends of the two second motors (16) respectively penetrate through the upper ends of the second reagent placing plates (7) and are respectively fixed with the two rotating blocks (19).
7. The reagent fixing mechanism for a gene assaying kit according to claim 1, wherein: two groups of limiting mechanisms (15) are arranged on two sides of the second reagent placing plate (7), each group of limiting mechanisms (15) comprises a rectangular groove (1501), a sliding rod (1502) and a sliding block (1503), the rectangular groove (1501) is formed in one side wall of the reagent box (1), the sliding rod (1502) is fixedly connected between the inner top wall and the inner bottom wall of the rectangular groove (1501), the sliding block (1503) is connected to the circumferential side of the sliding rod (1502) in a sliding manner, and the sliding block (1503) is fixedly connected to one side of the second reagent placing plate (7).
CN202322903925.4U 2023-10-27 2023-10-27 Reagent fixing mechanism of gene detection kit Active CN221050345U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202322903925.4U CN221050345U (en) 2023-10-27 2023-10-27 Reagent fixing mechanism of gene detection kit

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202322903925.4U CN221050345U (en) 2023-10-27 2023-10-27 Reagent fixing mechanism of gene detection kit

Publications (1)

Publication Number Publication Date
CN221050345U true CN221050345U (en) 2024-05-31

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ID=91198741

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202322903925.4U Active CN221050345U (en) 2023-10-27 2023-10-27 Reagent fixing mechanism of gene detection kit

Country Status (1)

Country Link
CN (1) CN221050345U (en)

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