CN221011673U - Pancreas supply preservation device for pancreas transplantation - Google Patents
Pancreas supply preservation device for pancreas transplantation Download PDFInfo
- Publication number
- CN221011673U CN221011673U CN202322677549.1U CN202322677549U CN221011673U CN 221011673 U CN221011673 U CN 221011673U CN 202322677549 U CN202322677549 U CN 202322677549U CN 221011673 U CN221011673 U CN 221011673U
- Authority
- CN
- China
- Prior art keywords
- pancreas
- sides
- bottom plate
- inner box
- frames
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 210000000496 pancreas Anatomy 0.000 title claims abstract description 65
- 238000002054 transplantation Methods 0.000 title claims abstract description 26
- 238000004321 preservation Methods 0.000 title claims abstract description 22
- 238000001816 cooling Methods 0.000 claims description 11
- 239000007788 liquid Substances 0.000 claims description 8
- 239000002826 coolant Substances 0.000 claims description 7
- 239000011521 glass Substances 0.000 claims description 6
- 238000007789 sealing Methods 0.000 claims description 5
- 239000004744 fabric Substances 0.000 claims description 2
- 238000009413 insulation Methods 0.000 abstract description 9
- 239000000110 cooling liquid Substances 0.000 abstract description 4
- 238000005057 refrigeration Methods 0.000 abstract 1
- 230000006378 damage Effects 0.000 description 7
- 230000000694 effects Effects 0.000 description 5
- 239000000463 material Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 230000008569 process Effects 0.000 description 3
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000006260 foam Substances 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 239000003761 preservation solution Substances 0.000 description 2
- 230000003068 static effect Effects 0.000 description 2
- ZKHQWZAMYRWXGA-KQYNXXCUSA-J ATP(4-) Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O ZKHQWZAMYRWXGA-KQYNXXCUSA-J 0.000 description 1
- ZKHQWZAMYRWXGA-UHFFFAOYSA-N Adenosine triphosphate Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C1O ZKHQWZAMYRWXGA-UHFFFAOYSA-N 0.000 description 1
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000005273 aeration Methods 0.000 description 1
- 230000002146 bilateral effect Effects 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 230000007012 clinical effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 208000028867 ischemia Diseases 0.000 description 1
- 210000004153 islets of langerhan Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000000082 organ preservation Substances 0.000 description 1
- 230000036284 oxygen consumption Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 239000003507 refrigerant Substances 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The utility model relates to the field of pancreas transplantation, in particular to a pancreas supply preservation device for pancreas transplantation, wherein outer shells are hinged to the left side and the right side of a bottom plate, heat insulation layers are correspondingly and fixedly arranged on the inner sides of the two outer shells, a top cover is placed on the two outer shells, an inner box body is fixedly arranged on the upper surface of the bottom plate, a placing bag is fixedly arranged at the top end of the inner box body, cooling liquid is filled in the inner box body, a supporting plate is fixedly arranged at the bottom of the left side and the right side of the bottom plate, the outer shells are hinged to the bottom plate, the pancreas supply is placed in the placing bag on the basis of realizing outside protection, meanwhile, the inner box body and the placing bag are arranged on the upper surface of the bottom plate, the pancreas supply is placed in the placing bag, not only can effectively resist impact caused by external collision, but also can realize refrigeration, cooling liquid is convenient to regulate temperature, temperature regulation fluctuation is gentle, and the pancreas supply preservation is facilitated.
Description
Technical Field
The utility model relates to the field of pancreas transplantation, in particular to a pancreas-supplying preservation device for pancreas transplantation.
Background
Type I diabetes is an organ-specific autoimmune disease, islet transplantation has been widely focused on treating type I diabetes, a certain clinical effect is achieved, at present, one of the problems faced by islet transplantation is that the pancreas of a high-quality donor is in shortage, especially the pancreas is preserved before islet preparation and islet culture is an important factor affecting the islet transplantation curative effect, therefore, how to prevent pancreas injury and islet function reduction during preservation is also a research hot spot, whether the pancreas of the donor is transplanted by pancreas or isolated and purified to carry out islet cell transplantation, the preservation method is mainly static low-temperature preservation, and the low-temperature (2-4 ℃) preservation can reduce ischemia injury by reducing the cell metabolism rate, oxygen consumption and adenosine triphosphate usage, and the preservation solution is beneficial to reducing adverse effects caused by low temperature.
Chinese utility model (CN 216661051U) discloses an organ preservation box for pancreas transportation, which is characterized in that a refrigerating cavity is used for loading refrigerants, a preservation solution and pancreas are loaded through a storage cavity, heat exchange is performed between the refrigerating cavity and the storage cavity through a heat exchange plate, and the storage cavity is used for providing a preservation temperature environment for pancreas, oxygen is introduced into the storage cavity through an aeration device and an oxygen tank, so that an aerobic ring shape is provided for pancreas, and pancreas damage is reduced.
Disclosure of utility model
The utility model aims to solve the defect that pancreas is possibly damaged under the action of low temperature and gravity in the prior art by singly placing pancreas in a filter basket, and provides a pancreas-supplying preservation device for pancreas transplantation.
In order to achieve the above purpose, the present utility model adopts the following technical scheme:
The utility model provides a supply pancreas save set for pancreas transplantation, includes the bottom plate, the bottom plate left and right sides all articulates installs the shell body, both sides the shell body is U type structure and symmetry setting, two the shell body inboard corresponds fixed mounting and has the insulating layer, two place the top cap on the shell body, fixed surface installs interior box on the bottom plate, interior box top fixed cloth has placed the bag, the intussuseption of interior box is filled with the coolant liquid, bottom fixed mounting has the backup pad in bottom plate left and right sides bottom.
Preferably, the inner box bottom is coiled and fixedly provided with a cooling pipe, the bottom plate bottom is fixedly provided with a temperature controller, and the temperature controller is connected with the cooling pipe at the inner box bottom.
Preferably, the side frames are fixedly installed on the front side and the rear side of the bottom plate, the limiting frames are rotatably installed on the outer sides of the upper ends of the side frames, sliding grooves are fixedly formed in the two sides of the limiting frames, limiting strips are fixedly installed on the front side and the rear side of the outer shell body and correspond to the limiting frames, and the limiting strips slide in the sliding grooves in the two sides of the limiting frames.
Preferably, auxiliary frames are hinged to the front side and the rear side of the outer shell on two sides.
Preferably, the lower surface of the top cover is fixedly provided with an extension frame, the extension frame is correspondingly matched with the upper end of the inner box body, and the lower end of the extension frame is fixedly provided with heat insulation glass.
Preferably, the top cover is provided with an observation hole in a penetrating mode, and a sealing cover is inserted into the observation hole.
Preferably, slots are symmetrically formed in two sides of the sealing cover.
The pancreas supply preservation device for pancreas transplantation has the beneficial effects that:
1. Through with the articulated installation of shell body at the bottom plate, on realizing outside protection's basis, also greatly facilitated the placing and taking of supplying pancreas, thereby effectively avoided, because of the box is darker, personnel take and put and supply pancreas damage that the pancreas is great to lead to, simultaneously through setting up interior box and placing the bag in the bottom plate upper surface, will supply pancreas to place in placing the bag, not only can effectively resist the impact that external collision brought, simultaneously pour into the coolant liquid in interior box, can realize cold-stored, the coolant liquid is convenient for adjust the temperature, and temperature regulation is undulant mild, do benefit to the save that supplies pancreas.
2. Through the cooperation of frame, spacing, can realize spacing fixed to two shells, avoid preserving two shells that lead to in the transportation process and scatter to rotatory spacing card is established and can be realized the locking of frame and shell at spacing and be connected the cooperation, more convenient and practical.
3. Through fixed extension frame that sets up in top cap lower surface to at extension frame lower extreme fixed mounting has thermal insulation glass, make in transportation preservation process, can effectively avoid supplying the pancreas damage because of temperature controller or cooling tube trouble lead to through the observation hole on the top cap, insert on the observation hole and be equipped with sealed lid, play sealed effect, also be convenient for simultaneously keep warm control.
Drawings
Fig. 1 is a schematic diagram showing a front view of a pancreas-preserving device for pancreas transplantation according to the present utility model.
Fig. 2 is a schematic diagram showing the structure of a pancreas-preserving device for pancreas transplantation according to the present utility model.
Fig. 3 is a schematic view showing a part of the structure of a pancreas-preserving device for pancreas transplantation according to the present utility model.
Fig. 4 is a schematic cross-sectional view of a pancreatic preservation device for pancreas transplantation according to the present utility model.
Fig. 5 is a schematic view of a limiting frame structure of a pancreas-preserving device for pancreas transplantation according to the present utility model.
In the figure: the heat insulation device comprises a bottom plate 1, an outer shell 2, a top cover 3, a heat insulation layer 4, an inner box 5, a placing bag 6, a temperature controller 7, side frames 8, a limit frame 9, a limit frame 10, an auxiliary frame 11, a supporting plate 12, an extension frame 13, heat insulation glass 14 and a sealing cover 15.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments.
Example 1
Referring to fig. 1-5, a pancreas supply preservation device for pancreas transplantation, including bottom plate 1, bottom plate 1 both sides all articulate and install shell body 2, shell body 2 of both sides is U type structure and symmetry setting, through articulated the installation of shell body 2 at bottom plate 1, on the basis of realizing outside protection, place and take for pancreas also greatly, thereby effectively avoided, because the box is darker, personnel take and put and supply pancreas damage that the pancreas is great to cause, two shell body 2 inboard corresponds fixed mounting has insulating layer 4, insulating layer 4 material is the foam, insulating layer 4's setting can show the control of reinforcing device internal temperature loss, be convenient for keep warm, top cap 3 has been placed on two shell bodies 2, bottom plate 1 upper surface fixed mounting has interior box 5, interior box 5 top fixedly lays placing bag 6, placing bag 6 is flexible material, and be waterproof material, can pour into pancreas preservation liquid in placing bag 6, be favorable to reducing the adverse effect that the low temperature brought to supplying pancreas, interior box 5 material is the foam, cooling plate 1 both sides bottom plate 12 is fixed mounting in the bottom plate 1.
The inner box 5 bottom is coiled a bent fixed mounting and has the cooling tube, bottom plate 1 bottom fixed mounting has temperature controller 7, temperature controller 7 is connected with the cooling tube of inner box 5 bottom, the temperature of the interior coolant liquid of temperature controller 7 accessible cooling tube regulation inner box 5 makes it keep in the temperature range about 2-4 ℃, simultaneously through setting up inner box 5 and placing bag 6 at bottom plate 1 upper surface, will supply pancreas to place in placing bag 6, not only can effectively resist the impact that external collision brought, simultaneously pour into the coolant liquid in inner box 5, can realize cold-stored, the coolant liquid is convenient for adjust the temperature, and the temperature regulation fluctuation is mild, do benefit to the save that supplies pancreas.
The equal fixed mounting in both sides around the bottom plate 1 has limit frame 8, the draw-in groove has been seted up to the shell body 2 of both sides corresponding to limit frame 8, limit frame 9 is installed in the rotation of limit frame 8 upper end outside, the spout has been fixedly seted up to limit frame 9 both sides, limit frame 9 fixed mounting has limit frame 10 to both sides corresponding to limit frame 2 around the shell body of both sides, limit frame 10 slides in limit frame 9 both sides spout, through limit frame 8, limit frame 9, limit frame 10's cooperation, can realize the spacing fixedly to two shell bodies 2, two shell bodies 2 that lead to in the storage transportation are avoided scattering, and rotatory limit frame 9 card is established and can be realized the locking of limit frame 8 and shell body 2 and is connected the cooperation, more convenient practicality.
The auxiliary frames 11 are hinged to the front side and the rear side of the outer shell 2 on the two sides, and the auxiliary frames 11 are arranged, so that the device is convenient to extract, and the transfer is more convenient and labor-saving.
Example 2
According to embodiment 1, the embodiment 1 can realize the low-temperature static state preservation of the supplied pancreas and is convenient to take and place, however, when the supplied pancreas is transported and preserved for a long time, as the temperature controller 7 or the cooling pipe has a certain probability of failure, the supplied pancreas state needs to be observed in the market, and the conventional cover opening observation can not only cause temperature imbalance but also cause pollution to the supplied pancreas, and referring to fig. 1-5, as another preferred embodiment of the utility model, on the basis of embodiment 1:
The top cap 3 lower surface fixed mounting has extension frame 13, extension frame 13 corresponds the matching with interior box 5 upper end, extension frame 13 lower extreme fixed mounting has thermal insulation glass 14, the observation hole has been run through on the top cap 3, sealed lid 15 has been inserted in the observation hole, sealed lid 15 bilateral symmetry has seted up the slot, through the fixed extension frame 13 that sets up of top cap 3 lower surface, and at extension frame 13 lower extreme fixed mounting has thermal insulation glass 14, make in transportation preservation process, can observe through the observation hole on the top cap 3, can effectively avoid supplying pancreas damage because of temperature controller 7 or cooling tube trouble lead to, it has sealed lid 15 to insert on the observation hole, play sealed effect, the while is also convenient for thermal insulation control.
Working principle: before pancreas is placed, the top cover 3 is firstly taken down in an aseptic chamber, at the moment, the limiting frame 9 is rotated, the limiting frame 10 is separated from contact with sliding grooves on two sides of the limiting frame 9, at the moment, the two outer shell bodies 2 are opened, the inner box body 5 and the placing bag 6 are exposed, at the moment, the temperature of cooling liquid in the inner box body 5 is adjusted through the temperature controller 7 to be about 2-4 ℃, a certain amount of cooling liquid is poured into the placing bag 6, then the pancreas is stably placed in the placing bag 6, the temperature is kept continuously through the temperature controller 7, then the two outer shell bodies 2 are combined, the limiting frame 9 is reversely rotated, locking fixation of the two outer shell bodies 2 is realized through the buckling connection of the limiting frame 9 and the limiting frame 10, then the top cover 3 is placed, and the lower end of the extending frame 13 below the top cover 3 is abutted against the upper end of the inner box body 5, so that double-layer sealed preservation is realized.
The foregoing is only a preferred embodiment of the present utility model, but the scope of the present utility model is not limited thereto, and any person skilled in the art, who is within the scope of the present utility model, should make equivalent substitutions or modifications according to the technical scheme of the present utility model and the inventive concept thereof, and should be covered by the scope of the present utility model.
Claims (7)
1. The utility model provides a supply pancreas save set for pancreas transplantation, includes bottom plate (1), its characterized in that, bottom plate (1) both sides all articulate and install shell body (2), both sides shell body (2) are U type structure and symmetry setting, two shell body (2) inboard corresponds fixed mounting has insulating layer (4), two top cap (3) have been placed on shell body (2), surface fixed mounting has interior box (5) on bottom plate (1), interior box (5) top fixed cloth has placed bag (6), interior box (5) intussuseption is filled with coolant liquid, bottom plate (1) both sides bottom fixed mounting has backup pad (12).
2. The pancreas-supplying preservation device for pancreas transplantation according to claim 1, wherein the bottom of the inner box body (5) is fixedly provided with a cooling pipe in a coiling way, the bottom of the bottom plate (1) is fixedly provided with a temperature controller (7), and the temperature controller (7) is connected with the cooling pipe at the bottom of the inner box body (5).
3. The pancreas supply preservation device for pancreas transplantation according to claim 2, wherein side frames (8) are fixedly installed on the front side and the rear side of the bottom plate (1), limiting frames (9) are rotatably installed on the outer sides of the upper ends of the side frames (8), sliding grooves are fixedly formed in the two sides of the limiting frames (9), limiting strips (10) are fixedly installed on the front side and the rear side of the outer shell (2) on the two sides, corresponding to the limiting frames (9), of the limiting frames, and the limiting strips (10) slide in the sliding grooves on the two sides of the limiting frames (9).
4. The pancreas-preserving device for pancreas transplantation according to claim 2, wherein the outer casing (2) on both sides is hinged with auxiliary frames (11) on front and rear sides.
5. The pancreas-supplying preservation device for pancreas transplantation according to claim 2, wherein an extension frame (13) is fixedly mounted on the lower surface of the top cover (3), the extension frame (13) is correspondingly matched with the upper end of the inner box body (5), and a heat-insulating glass (14) is fixedly mounted on the lower end of the extension frame (13).
6. The pancreas-preserving device for pancreas transplantation according to claim 5, wherein the top cover (3) is provided with a through-hole, and a sealing cover (15) is inserted into the through-hole.
7. The pancreas-preserving device for pancreas transplantation according to claim 6, wherein the sealing cover (15) is symmetrically provided with slots on both sides.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322677549.1U CN221011673U (en) | 2023-10-08 | 2023-10-08 | Pancreas supply preservation device for pancreas transplantation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322677549.1U CN221011673U (en) | 2023-10-08 | 2023-10-08 | Pancreas supply preservation device for pancreas transplantation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN221011673U true CN221011673U (en) | 2024-05-28 |
Family
ID=91187907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322677549.1U Active CN221011673U (en) | 2023-10-08 | 2023-10-08 | Pancreas supply preservation device for pancreas transplantation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN221011673U (en) |
-
2023
- 2023-10-08 CN CN202322677549.1U patent/CN221011673U/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN221011673U (en) | Pancreas supply preservation device for pancreas transplantation | |
| CN212299589U (en) | Passive medical refrigerator | |
| CN218432403U (en) | Transport case is used in quick-freeze food transportation | |
| CN113859722B (en) | Fridge is used in cold chain transportation | |
| CN212087799U (en) | Human placenta transportation equipment | |
| CN213444191U (en) | Lung tumor cell cryogenic refrigeration conveyer | |
| CN213911204U (en) | Ice coffin for remains refrigeration by liquid nitrogen | |
| CN221522553U (en) | Biological CK-MB reagent raw materials low temperature save set | |
| CN108775743A (en) | A kind of dry ice cooling air formula refrigeration case | |
| CN207180126U (en) | A kind of royal jelly packing box and the packing case placed for packing box | |
| CN215454964U (en) | Novel cell cryopreserving device | |
| CN213800847U (en) | Box is placed to insulin convenient to carry | |
| CN221893540U (en) | Fresh-keeping turnover case of agricultural product storage | |
| CN208360935U (en) | A kind of transport case saved for donor lung organ | |
| CN218752527U (en) | Circulation turnover box for low-temperature preservation of medicines | |
| CN215602678U (en) | Transfer transition device for shrimp culture | |
| CN217742909U (en) | A protection device that is arranged in kidney cold ischemia of open kidney operation | |
| CN221554522U (en) | Vitrification freezing and storing perfusion device | |
| CN217888083U (en) | Multifunctional test tube box | |
| CN216425424U (en) | Jujube fruit postharvest fresh-keeping device | |
| CN221802177U (en) | Ultralow temperature refrigerator | |
| CN215134718U (en) | Frozen electronic infusion device | |
| CN216106961U (en) | Small-volume dry cell resuscitator | |
| CN213229893U (en) | L-leucine mother liquor recovery unit | |
| CN218432488U (en) | Medical cold chain combination box |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |