CN220987378U

CN220987378U - Preservation device for germ line embryonic stem cells

Info

Publication number: CN220987378U
Application number: CN202323111637.1U
Authority: CN
Inventors: 周芬; 张艳红
Original assignee: JINING NO1 PEOPLE'S HOSPITAL
Current assignee: JINING NO1 PEOPLE'S HOSPITAL
Priority date: 2023-11-17
Filing date: 2023-11-17
Publication date: 2024-05-24
Anticipated expiration: 2033-11-17

Abstract

The utility model relates to the technical field of storage of germ cells, in particular to a storage device of germ cells, which comprises a box body, wherein the top end of the box body is hinged with a cover plate, a top plate and a supporting plate are fixed in the box body, the top of the top plate is provided with a picking and placing assembly, the top of the supporting plate is provided with a placing seat, the placing seat is provided with a plurality of circularly distributed placing grooves, a storage rack is inserted in the placing groove, the top end of the supporting plate is provided with a lifting groove, a jacking block is inserted in the lifting groove, the bottom of the box body is provided with a jacking assembly connected with the bottom of the jacking block, and the bottom of the box body is provided with a driving mechanism capable of periodically rotating.

Description

Preservation device for germ line embryonic stem cells

Technical Field

The utility model relates to the technical field of germ cell stem cell preservation, in particular to a germ cell stem cell preservation device.

Background

Currently, stem cells are a relatively specialized cell that can develop into other cells. In particular embryonic stem cells, germ embryonic stem cells develop into any cell, such as neural cells, cardiomyocytes, and the like. Stem cell reproduction can therefore be used to repair damaged individual organs of the human body, treating many other diseases that are refractory to other methods.

In stem cell clinical research, the stem cells are stored in the freezing storage pipes and are placed in the storage boxes, and if one freezing storage pipe needs to be taken out, the storage boxes are completely opened by the existing freezing device, so that the freezing storage effect of the stem cells in other freezing storage pipes in the storage boxes is affected, and the taking and the placing are inconvenient.

Disclosure of utility model

The present utility model is directed to a preservation device for germ line embryonic stem cells, which solves the problems set forth in the background art.

The technical scheme of the utility model is as follows: the utility model provides a save set of germ line stem cell, includes the box, the box top articulates there is the apron, be fixed with roof and layer board in the box, get at the top of roof and put the subassembly, the layer board top is provided with places the seat, place and set up a plurality of annular distribution's thing grooves of putting on the seat, put thing inslot and sliding insert the supporter, the lift groove has been seted up on the layer board top, the lift inslot sliding insert the jacking piece, the bottom of the case install with jacking subassembly that jacking piece bottom is connected, but the actuating mechanism of periodic rotation work is installed to the bottom of the case portion, actuating mechanism's output passes layer board top outer wall with place the seat bottom and be connected, install on the bottom of the case portion inner wall with the liquid nitrogen cold source of layer board top intercommunication.

The effects achieved by the components are as follows: can seal work through apron and roof top, under apron and getting and putting the subassembly open state, drive jacking piece upward movement through jacking subassembly, the jacking piece is along the lift groove upward movement until will put the supporter of thing inslot and put the inboard ejecting to the roof outside of subassembly from getting, realize the independent work purpose of getting of putting to stem cell, wherein actuating mechanism can drive and put the seat and rotate until the supporter bottom that needs get and put contradicts with the jacking piece top, facilitate the use.

Preferably, the driving mechanism comprises a rotating shaft connected with the bottom end of the placement seat, a transmission gear is fixed at the bottom end of the rotating shaft penetrating through the bottom of the supporting plate, a driving gear is meshed with one side of the transmission gear, and a stepping motor is connected with the driving gear in a transmission manner.

The effects achieved by the components are as follows: the rotating shaft on the driving gear and the transmission gear can be matched with the stepping motor to drive the placing seat to rotate, so that the placing seat can be conveniently used for taking and placing different storage racks.

Preferably, the jacking component comprises a jacking rod rotatably mounted on the inner wall of the bottom of the box body, the top end of the jacking rod is attached to the bottom of the jacking block, and an electric telescopic rod is rotatably connected between one side of the bottom of the jacking rod and the inner wall of the bottom of the box body.

The effects achieved by the components are as follows: the electric telescopic rod drives the lifting rod to turn upwards in the extension state, and the top end of the lifting rod lifts the lifting block upwards in the rotation process, so that the lifting block can be lifted upwards.

Preferably, the top end of the jacking rod is rotatably provided with a supporting wheel, and the outer wall of the top end of the supporting wheel is in contact with the bottom of the jacking block.

The effects achieved by the components are as follows: the supporting wheels can enable the jacking rod and the bottom of the jacking block to move in a relatively fitting mode more smoothly.

Preferably, the liquid nitrogen cold source comprises a liquid nitrogen storage tank, a discharge hole of the liquid nitrogen storage tank is connected with a heat preservation pipe, one end of the heat preservation pipe, which is far away from the liquid nitrogen storage tank, extends to the top of the supporting plate, and a valve is arranged on the heat preservation pipe.

The effects achieved by the components are as follows: after the valve in the liquid nitrogen cold source is opened, liquid nitrogen is discharged from the liquid nitrogen storage tank and enters the periphery of the placement seat along the heat preservation pipe, so that the aim of cryopreservation of stem cells is fulfilled.

Preferably, the picking and placing assembly comprises a picking and placing opening formed in the top plate, and a flip cover is hinged to the edge of the top end of the picking and placing opening.

The effects achieved by the components are as follows: through opening flip, can be convenient for follow and get and put the mouth and get and put the work of stem cell.

Preferably, a handle is fixed at the top of the cover plate, and a sealing ring embedded with the top of the box body is fixed at the bottom end of the cover plate.

The effects achieved by the components are as follows: the cover plate can be conveniently opened and sealed through the handle and the sealing ring.

The utility model provides a preservation device for germ cells by improving, which has the following improvements and advantages compared with the prior art:

The method comprises the following steps: according to the utility model, the jacking block is driven to move upwards by the jacking component, and moves upwards along the lifting groove until the storage rack in the storage groove is ejected out of the top plate from the inner side of the picking and placing component, so that the independent picking and placing work of stem cells is realized, wherein the driving mechanism can drive the placing seat to rotate until the bottom end of the storage rack to be picked and placed is abutted against the top end of the jacking block, and the use is convenient;

And two,: according to the utility model, the electric telescopic rod drives the lifting rod to turn upwards in the extension state, the top end of the lifting rod upwards lifts the lifting block in the rotation process, the upward lifting work purpose of the lifting block is realized, and the lifting rod and the bottom of the lifting block can be relatively attached and moved smoothly through the supporting wheel.

Drawings

The utility model is further explained below with reference to the drawings and examples:

FIG. 1 is a schematic perspective view of the present utility model;

FIG. 2 is a schematic cross-sectional perspective view of the present utility model;

FIG. 3 is a schematic cross-sectional view of the present utility model;

Fig. 4 is a schematic structural view of a jacking assembly according to the present utility model.

Reference numerals illustrate:

1. A case; 2. a cover plate; 3. a top plate; 4. a taking and placing port; 5. a flip cover; 6. a supporting plate; 7. a driving mechanism; 71. a stepping motor; 72. a drive gear; 73. a transmission gear; 74. a rotating shaft; 8. a jacking assembly; 81. a lifting rod; 82. a support wheel; 83. an electric telescopic rod; 9. a jacking block; 10. a storage groove; 11. a placement seat; 12. a liquid nitrogen cold source; 13. a lifting groove; 14. and a commodity shelf.

Detailed Description

The following detailed description of the present utility model clearly and fully describes the technical solutions of the embodiments of the present utility model, and it is apparent that the described embodiments are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

The utility model provides a preservation device of germ embryo stem cells by improving the preservation device, and the technical scheme of the utility model is as follows:

In the embodiment of the utility model, as shown in fig. 1-4, a preservation device for germ stem cells comprises a box body 1, wherein the top end of the box body 1 is hinged with a cover plate 2, the top of the cover plate 2 is fixed with a handle, the bottom end of the cover plate 2 is fixed with a sealing ring jogged with the top end of the box body 1, a top plate 3 and a supporting plate 6 are fixed in the box body 1, a picking and placing component is arranged at the top of the top plate 3 and comprises a picking and placing opening 4 arranged on the top plate 3, a flip cover 5 is hinged at the edge of the top end of the picking and placing opening 4, a placement seat 11 is arranged at the top of the supporting plate 6, a plurality of circularly distributed placement grooves 10 are arranged on the placement seat 11, a storage rack 14 is inserted in the placement groove 10, a lifting groove 13 is arranged at the top end of the supporting plate 6, a lifting block 9 is inserted in the lifting groove 13, a lifting component 8 connected with the bottom of the lifting block 9 is arranged at the bottom of the box body 1, the driving mechanism 7 capable of periodically rotating is arranged at the bottom of the box body 1, the output end of the driving mechanism 7 penetrates through the outer wall of the top of the supporting plate 6 and is connected with the bottom of the placement seat 11, the jacking block 9 is driven to move upwards through the jacking component 8, the jacking block 9 moves upwards along the lifting groove 13 until the storage rack 14 in the storage groove 10 is ejected out of the top plate 3 from the inner side of the taking and placing component, the independent taking and placing work purpose of stem cells is achieved, the driving mechanism 7 can drive the placement seat 11 to rotate until the bottom end of the storage rack 14 which needs to be taken and placed is in contact with the top end of the jacking block 9, the liquid nitrogen cold source 12 communicated with the top end of the supporting plate 6 is arranged on the inner wall of the bottom of the box body 1, the liquid nitrogen cold source 12 comprises a liquid nitrogen storage tank, a heat preservation pipe is connected to a discharge port of the liquid nitrogen storage tank, one end of the heat preservation pipe far away from the liquid nitrogen storage tank extends to the top of the supporting plate 6, and a valve is arranged on the heat preservation pipe.

In the embodiment of the utility model, the driving mechanism 7 comprises a rotating shaft 74 connected with the bottom end of the placing seat 11, a transmission gear 73 is fixed at the bottom end of the rotating shaft 74 penetrating through the bottom of the supporting plate 6, one side of the transmission gear 73 is meshed with and transmitted with a driving gear 72, the driving gear 72 is in transmission connection with a stepping motor 71, and the placing seat 11 can be driven to rotate by the stepping motor 71 in cooperation with the driving gear 72 and the rotating shaft 74 on the transmission gear 73, so that the placing and taking of different storage racks 14 can be conveniently carried out.

In the embodiment of the utility model, the jacking component 8 comprises a jacking rod 81 rotatably installed on the inner wall of the bottom of the box body 1, the top end of the jacking rod 81 is attached to the bottom of the jacking block 9, an electric telescopic rod 83 is rotatably connected between one side of the bottom of the jacking rod 81 and the inner wall of the bottom of the box body 1, the jacking rod 81 is driven to upwards overturn in an elongation state through the electric telescopic rod 83, the jacking block 9 is upwards jacked up in the rotation process by the top end of the jacking rod 81, the upward lifting work of the jacking block 9 is realized, a supporting wheel 82 is rotatably installed on the top end of the jacking rod 81, the outer wall of the top end of the supporting wheel 82 is abutted to the bottom of the jacking block 9, and the jacking rod 81 and the bottom of the jacking block 9 can be relatively attached to move smoothly through the supporting wheel 82.

The utility model provides a preservation device for germ cells, which has the following working principle: the top of the box body 1 can be sealed through the cover plate 2 and the top plate 3, under the opening state of the cover plate 2 and the flip cover 5, the storage seat 11 can be driven to rotate by utilizing the stepping motor 71 to match with the rotating shaft 74 on the driving gear 72 and the transmission gear 73 until the bottom end of the storage rack 14 to be taken and placed is abutted against the top end of the jacking block 9, the jacking rod 81 is driven to upwards overturn when the electric telescopic rod 83 is in an extension state, the jacking block 9 is upwards jacked in the rotating process by the top end of the jacking rod 81, the jacking block 9 moves upwards along the lifting groove 13 until the storage rack 14 in the storage groove 10 is lifted out of the top plate 3 from the inner side of the taking and placing component, and the independent taking and placing work purpose of stem cells is achieved.

Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The utility model provides a preservation device of reproduction embryo stem cell, includes box (1), box (1) top articulates there is apron (2), its characterized in that: the utility model discloses a liquid nitrogen cold source, including box (1), roof (3) and layer board (6) are fixed with in, get and put subassembly has been seted up at the top of roof (3), layer board (6) top is provided with places seat (11), place and set up a plurality of annular distribution on seat (11) put thing groove (10), put thing inslot (10) interior shelf (14), lifting groove (13) have been seted up on layer board (6) top, jack-up piece (9) have been inserted in lifting groove (13), install in box (1) bottom with jack-up subassembly (8) that jack-up piece (9) bottom is connected, but drive mechanism (7) of periodic rotation work are installed to box (1) bottom, the output of drive mechanism (7) pass layer board (6) top outer wall with place seat (11) bottom and be connected, install on box (1) bottom inner wall with liquid nitrogen cold source (12) of layer board (6) top intercommunication.

2. The preservation apparatus of germ line embryonic stem cells of claim 1 wherein: the driving mechanism (7) comprises a rotating shaft (74) connected with the bottom end of the placement seat (11), a transmission gear (73) penetrates through the bottom of the supporting plate (6) at the bottom end of the rotating shaft (74), a driving gear (72) is meshed and transmitted on one side of the transmission gear (73), and a stepping motor (71) is connected with the driving gear (72) in a transmission mode.

3. The preservation apparatus of germ line embryonic stem cells of claim 1 wherein: jacking subassembly (8) are including rotating to install jacking rod (81) on box (1) bottom inner wall, the top of jacking rod (81) with the laminating of the bottom of jacking piece (9), the bottom one side of jacking rod (81) with rotate between box (1) bottom inner wall and be connected with electric telescopic handle (83).

4. A preservation apparatus of germ line embryonic stem cells according to claim 3, wherein: the top end of the jacking rod (81) is rotatably provided with a supporting wheel (82), and the outer wall of the top end of the supporting wheel (82) is abutted to the bottom of the jacking block (9).

5. The preservation apparatus of germ line embryonic stem cells of claim 1 wherein: the liquid nitrogen cold source (12) comprises a liquid nitrogen storage tank, a discharge hole of the liquid nitrogen storage tank is connected with a heat preservation pipe, one end, far away from the liquid nitrogen storage tank, of the heat preservation pipe extends to the top of the supporting plate (6), and a valve is arranged on the heat preservation pipe.

6. The preservation apparatus of germ line embryonic stem cells of claim 1 wherein: the picking and placing assembly comprises a picking and placing opening (4) formed in the top plate (3), and a flip cover (5) is hinged to the edge of the top end of the picking and placing opening (4).

7. The preservation apparatus of germ line embryonic stem cells of claim 1 wherein: the top of apron (2) is fixed with the handle, apron (2) bottom be fixed with sealing washer of box (1) top gomphosis.