CN220916345U

CN220916345U - Cell cryopreservation box

Info

Publication number: CN220916345U
Application number: CN202322725127.7U
Authority: CN
Inventors: 童振飞; 张可妍; 吴单
Original assignee: Zhejiang Inotai Medical Devices Co ltd
Current assignee: Zhejiang Inotai Medical Devices Co ltd
Priority date: 2023-10-09
Filing date: 2023-10-09
Publication date: 2024-05-10
Anticipated expiration: 2033-10-09

Abstract

The application discloses a cell freezing and preserving box, which comprises a cell freezing and preserving box, a cell preserving pipe, a connecting structure, an air exhausting structure, a drawing structure and a supporting structure, wherein the inner side wall of the cell freezing and preserving box is fixedly connected with a partition plate, and the top side wall of the cell freezing and preserving box is fixedly connected with a freezing and preserving shell at equal distance. According to the application, the cell storage tube is pulled outwards by rotating the handle, the second ventilation tube sucks vaporized liquid nitrogen above the supporting plate into the tube all the time, so that the phenomenon that a large amount of vaporized liquid nitrogen overflows the cell freezing storage box to cause loss of cold air and waste of liquid nitrogen in the process of taking out the cell storage tube is avoided.

Description

Cell cryopreservation box

Technical Field

The application relates to the field of cell cryopreservation, in particular to a cell cryopreservation box.

Background

Cell cryopreservation is a technology for placing cells in a low-temperature environment to reduce cell metabolism so as to facilitate long-term storage, and is one of the main methods for cell preservation, plays a role in cell seed preservation, and a special cell cryopreservation box is usually used during cell cryopreservation.

CN205794635U discloses a stem cell cryopreservation box. The device comprises a top-open type box body, wherein a supporting mechanism for fixing a stem cell cold storage tube is arranged in the box body, the supporting mechanism consists of a limiting plate and a supporting plate, through holes are uniformly distributed on the limiting plate, and supporting grooves are uniformly distributed on the supporting plate; the cooling box is arranged below the supporting plate, the cooling box is installed and removed in a side-open mode through an opening formed in the side portion of the box body, a sliding groove is formed in the position, above the opening, of the box body, and a bolt is installed in the sliding groove. The utility model has simple structure, the cooling box can be put in and taken out from the side part of the box body, the operation is convenient, the replacement of the cooling agent can be completed without opening the box body, and the quality of stem cell products is ensured.

The prior art has the technical problems that the door of the freezing preservation box is integral, and when cells are stored and taken, the whole top of the freezing preservation box is required to be opened, so that a large amount of cold air in the freezing preservation box is lost, the refrigerating effect in the preservation box is affected, and meanwhile, other frozen cells are affected to a certain extent.

Therefore, it is desirable to provide a cell cryopreservation tank capable of avoiding a large amount of vaporized liquid nitrogen overflowing the cell cryopreservation tank during the process of taking out the cell storage tube, causing a loss of cool air and a waste of liquid nitrogen and not affecting cryopreservation of other cell storage tubes when placing and taking out the single cell storage tube.

Disclosure of Invention

The embodiment provides a cell cryopreservation box for solving the problems that a large amount of cold air flows and influences on other cryopreserved cells can be caused when the cells are stored and taken in the prior art.

According to one aspect of the application, a cell freezing box is provided, which comprises a cell freezing box and a cell storage tube, and further comprises a connecting structure, an air draft structure, a drawing structure and a propping structure, wherein the inner side wall of the cell freezing box is fixedly connected with a partition plate, the top side wall of the cell freezing box is fixedly connected with a freezing shell in an equidistant manner, the bottom of the freezing shell is fixedly connected with the partition plate, the freezing shell and the partition plate are provided with the air draft structure, the drawing structure is arranged in the freezing shell, the drawing structure is provided with the propping structure, the cell storage tube is clamped between the drawing structure and the propping structure, the bottom of the cell storage tube is fixedly connected with a clamping block, the outer side wall of the cell freezing box is fixedly connected with a fixed ring plate, and the cell freezing box is connected with a top cover through the connecting structure.

Further, the middle of the top of the cell freezing and preserving box is a circular downward concave, and a threaded sleeve is fixedly connected to the concave of the cell freezing and preserving box.

Further, connection structure includes carousel, connecting rod, turning block and threaded rod, the turning block rotates to be connected on the lateral wall of top cap, the bottom fixed connection threaded rod of turning block, threaded rod and screw sleeve mutually support, the top fixed connection connecting rod of turning block, the top fixed connection carousel of connecting rod.

Further, pull structure includes layer board, fixed block, joint groove, slide bar, sealed pad and fixed plate, slide bar sliding connection is on the top lateral wall of cell cryopreservation case, the bottom fixed connection layer board of slide bar, layer board sliding connection is in the cryopreserved casing, fixed connection fixed block on the top lateral wall of layer board, the joint groove has been seted up on the lateral wall of fixed block, the top fixed connection fixed plate of slide bar, fixed connection is sealed pad on the lateral wall that the fixed plate is close to cell cryopreservation case.

Further, the sealing gasket is made of rubber.

Further, the clamping groove and the clamping block are matched with each other.

Further, support tight structure including rotating handle, connecting plate and support tight pole, be provided with the external screw thread on the lateral wall of supporting tight pole, support tight pole threaded connection on the lateral wall of fixed plate, the top fixed connection connecting plate of supporting tight pole, fixed connection rotates the handle on the top lateral wall of connecting plate.

Further, the air draft structure comprises a ventilating drum, a fan, a first ventilating pipe, a second ventilating pipe and a second fan, wherein the ventilating drum is fixedly connected to the side wall of the partition plate, the fan is fixedly connected to the inner side wall of the ventilating drum, one ends of the first ventilating pipe and the second ventilating pipe are fixedly connected to the side wall of the freezing storage shell, the other end of the first ventilating pipe is fixedly connected to the side wall of the ventilating drum, the other end of the second ventilating pipe is fixedly connected to the side wall of the partition plate, the other end of the second ventilating pipe is circularly expanded, and the second fan is fixedly connected to the inner side wall of the second ventilating pipe.

Further, the first ventilation pipe and the second ventilation pipe are respectively positioned at two sides of the freezing storage shell.

Further, the top equidistance of cell cryopreservation case leaves and is equipped with circular logical groove, the size in circular logical groove and cell deposit the pipe and support tight pole and mutually support, the position in circular logical groove corresponds each other with the position of cryopreservation casing, fixed connection feed liquor pipe on the left lateral wall of cell cryopreservation case, threaded connection has the dome on the feed liquor pipe, the feed liquor pipe is located the below of division board.

According to the embodiment of the application, the air draft structure, the drawing structure and the abutting structure are adopted, so that the problems that a large amount of cold air flows and other frozen cells are influenced when the cells are stored and taken are solved, and the effects that the loss of cold air and the waste of liquid nitrogen are caused when vaporized liquid nitrogen overflows out of a cell freezing box in a large amount in the process of taking out the cell storage tube, the cell storage tube is fixed in the drawing structure conveniently and the freezing of other cell storage tubes is not influenced when the single cell storage tube is placed and taken are achieved.

Drawings

In order to more clearly illustrate the embodiments of the application or the technical solutions of the prior art, the drawings which are used in the description of the embodiments or the prior art will be briefly described, it being obvious that the drawings in the description below are only some embodiments of the application, and that other drawings can be obtained from these drawings without inventive faculty for a person skilled in the art.

FIG. 1 is a schematic overall perspective view of an embodiment of the present application;

FIG. 2 is a schematic diagram of the overall internal structure of an embodiment of the present application;

FIG. 3 is a schematic diagram of the overall top view internal structure of an embodiment of the present application;

Fig. 4 is a schematic perspective view of a drawing structure and a tightening structure according to an embodiment of the present application.

In the figure: 1. a cell cryopreservation box; 2. a fixed ring plate; 3. a top cover; 4. a connection structure; 401. a turntable; 402. a connecting rod; 403. a rotating block; 404. a threaded rod; 5. a partition plate; 6. an air draft structure; 601. a ventilation tube; 602. a first fan; 603. a first ventilation pipe; 604. a second ventilating pipe; 605. a second fan; 7. freezing and storing the shell; 8. a drawing structure; 801. a supporting plate; 802. a fixed block; 803. a clamping groove; 804. a slide bar; 805. a sealing gasket; 806. a fixing plate; 9. a threaded sleeve; 10. a tightening structure; 1001. rotating the handle; 1002. a connecting plate; 1003. a tightening rod; 11. a cell storage tube; 12. a clamping block; 13. a circular through groove; 14. a dome; 15. a liquid inlet pipe.

Detailed Description

In order that those skilled in the art will better understand the present application, a technical solution in the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings in which it is apparent that the described embodiments are only some embodiments of the present application, not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the present application without making any inventive effort, shall fall within the scope of the present application.

It should be noted that the terms "first," "second," and the like in the description and the claims of the present application and the above figures are used for distinguishing between similar objects and not necessarily for describing a particular sequential or chronological order. It is to be understood that the data so used may be interchanged where appropriate in order to describe the embodiments of the application herein. Furthermore, the terms "comprises," "comprising," and "having," and any variations thereof, are intended to cover a non-exclusive inclusion, such that a process, method, system, article, or apparatus that comprises a list of steps or elements is not necessarily limited to those steps or elements expressly listed but may include other steps or elements not expressly listed or inherent to such process, method, article, or apparatus.

In the present application, the terms "upper", "lower", "left", "right", "front", "rear", "top", "bottom", "inner", "outer", "middle", "vertical", "horizontal", "lateral", "longitudinal" and the like indicate an azimuth or a positional relationship based on that shown in the drawings. These terms are only used to better describe the present application and its embodiments and are not intended to limit the scope of the indicated devices, elements or components to the particular orientations or to configure and operate in the particular orientations.

Also, some of the terms described above may be used to indicate other meanings in addition to orientation or positional relationships, for example, the term "upper" may also be used to indicate some sort of attachment or connection in some cases. The specific meaning of these terms in the present application will be understood by those of ordinary skill in the art according to the specific circumstances.

Furthermore, the terms "mounted," "configured," "provided," "connected," "coupled," and "sleeved" are to be construed broadly. For example, it may be a fixed connection, a removable connection, or a unitary construction; may be a mechanical connection, or an electrical connection; may be directly connected, or indirectly connected through intervening media, or may be in internal communication between two devices, elements, or components. The specific meaning of the above terms in the present application can be understood by those of ordinary skill in the art according to the specific circumstances.

It should be noted that, without conflict, the embodiments of the present application and features of the embodiments may be combined with each other. The application will be described in detail below with reference to the drawings in connection with embodiments.

Referring to fig. 1-4, a cell freezing box comprises a cell freezing box 1 and a cell storage tube 11, and further comprises a connecting structure 4, an air draft structure 6, a drawing structure 8 and a propping structure 10, wherein a partition plate 5 is fixedly connected to the inner side wall of the cell freezing box 1, a freezing shell 7 is fixedly connected to the top side wall of the cell freezing box 1 at equal intervals, the bottom of the freezing shell 7 is fixedly connected to the partition plate 5, the air draft structure 6 is arranged on the freezing shell 7 and the partition plate 5, a drawing structure 8 is arranged in the freezing shell 7, a propping structure 10 is arranged on the drawing structure 8, a cell storage tube 11 is clamped between the drawing structure 8 and the propping structure 10, a clamping block 12 is fixedly connected to the bottom of the cell storage tube 11, a fixing ring plate 2 is fixedly connected to the outer side wall of the cell freezing box 1, and a top cover 3 is connected to the cell freezing box 1 through the connecting structure 4.

The middle of the top of the cell freezing and preserving box 1 is provided with a circular downward recess, and a threaded sleeve 9 is fixedly connected to the recess of the cell freezing and preserving box 1.

The connection structure 4 includes carousel 401, connecting rod 402, dwang 403 and threaded rod 404, dwang 403 rotates to be connected on the lateral wall of top cap 3, the bottom fixed connection threaded rod 404 of dwang 403, threaded rod 404 and screw sleeve 9 mutually support, the top fixed connection connecting rod 402 of dwang 403, the top fixed connection carousel 401 of connecting rod 402 rotates carousel 401, rotates and drives dwang 403 rotation, and dwang 403 drives threaded rod 404 rotation, and threaded rod 404 rotates and takes place to remove at screw sleeve 9 rotation, drives top cap 3 decline, and top cap 3 cup joints the top at cell cryopreservation case 1.

The pull structure 8 comprises a supporting plate 801, a fixed block 802, a clamping groove 803, a sliding rod 804, a sealing gasket 805 and a fixed plate 806, wherein the sliding rod 804 is slidably connected to the top side wall of the cell freezing box 1, the bottom of the sliding rod 804 is fixedly connected with the supporting plate 801, the supporting plate 801 is slidably connected in the freezing box 7, the fixed block 802 is fixedly connected to the top outer side wall of the supporting plate 801, the clamping groove 803 is formed in the side wall of the fixed block 802, the fixed plate 806 is fixedly connected to the top of the sliding rod 804, the fixed plate 806 is close to the sealing gasket 805 on the outer side wall of the cell freezing box 1, the fixed plate 806 is pulled outwards through the rotating handle 1001, the fixed plate 806 drives the supporting plate 801 to move through the sliding rod 804, and the fixed cell storage tube 11 is driven to move by the pushing plate.

The gasket 805 is made of rubber, and the rubber has a good sealing effect.

The clamping groove 803 and the clamping block 12 are matched with each other.

The tight structure 10 is including rotating handle 1001, connecting plate 1002 and tight pole 1003 of support, be provided with the external screw thread on the lateral wall of tight pole 1003 of support, tight pole 1003 threaded connection is on the lateral wall of fixed plate 806, the top fixed connection connecting plate 1002 of tight pole 1003 of support, fixed connection rotates handle 1001 on the top lateral wall of connecting plate 1002, rotates handle 1001 and drives connecting plate 1002 rotation, and connecting rod 402 drives tight pole 1003 rotation, and tight pole 1003 rotation and downwardly moving support the top of cell storage tube 11.

The air draft structure 6 comprises an air draft tube 601, a first fan 602, an air draft tube 603, an air draft tube 604 and a second fan 605, wherein the air draft tube 601 is fixedly connected to the side wall of the partition plate 5, the first fan 602 is fixedly connected to the inner side wall of the air draft tube 601, one ends of the air draft tube 603 and the air draft tube 604 are fixedly connected to the side wall of the freezing storage shell 7, the other end of the air draft tube 603 is fixedly connected to the side wall of the air draft tube 601, the other end of the air draft tube 604 is fixedly connected to the side wall of the partition plate 5, the other end of the air draft tube 604 is circularly expanded, the air draft tube 605 is fixedly connected to the inner side wall of the air draft tube 604, the air draft tube 602 is used for exhausting gasified liquid nitrogen into the air draft tube 601, the gasified liquid nitrogen is fed into the freezing storage shell 7 through the air draft tube 603, and gasified liquid nitrogen in the freezing storage shell 7 is returned into the cavity below the partition plate 5 to form circulation.

The first ventilation pipe 603 and the second ventilation pipe 604 are respectively located at two sides of the freezing storage shell 7.

The top equidistance of the cell cryopreservation case 1 leaves and is equipped with circular logical groove 13, the size in circular logical groove 13 and cell deposit pipe 11 and support tight pole 1003 mutually support, the position in circular logical groove 13 corresponds with the position of cryopreservation casing 7 each other, fixed connection feed liquor pipe 15 on the lateral wall in cell cryopreservation case 1 left side, threaded connection has dome 14 on the feed liquor pipe 15, feed liquor pipe 15 is located the below of division board 5.

When the utility model is used, the electrical components are externally connected with a power supply and a control switch when the utility model is used, cells are stored in the cell storage tube 11 when the cells are frozen, then the clamping blocks 12 at the bottom of the cell storage tube 11 are clamped in the clamping grooves 803, the rotating handle 1001 is rotated, the rotating handle 1001 drives the connecting plate 1002 to rotate, the connecting rod 402 drives the abutting rod 1003 to rotate, the abutting rod 1003 rotates and moves downwards to abut against the top of the cell storage tube 11, the cell storage tube 11 is fixed between the drawing structures 8, the drawing structures 8 and the cell storage tube 11 are pushed back into the freezing shell 7, the threaded rod 404 is connected into the threaded sleeve 9 in a threaded manner, the rotating turntable 401 rotates to drive the rotating block 403 to rotate, the threaded rod 404 rotates in the threaded sleeve 9 and moves to drive the top cover 3 to descend, the top cover 3 is sleeved at the top of the cell freezing and preserving box 1, the top cover 3 tightly presses the rotary handle 1001, so that the sealing gasket 805 tightly abuts against the top of the cell freezing and preserving box 1 for sealing, and each freezing and preserving shell 7 is independently arranged and is not mutually interfered, so that when the single cell storing tube 11 is placed and taken, the freezing and preserving of other cell storing tubes 11 can not be influenced, liquid nitrogen can be injected into a cavity at the bottom of the partition plate 5 through the liquid inlet tube 15, the fan I602 is used for exhausting air, the vaporized liquid nitrogen is pumped into the ventilating tube 601, then the vaporized liquid nitrogen is sent into the freezing and preserving shell 7 through the ventilating tube I603, the fan II 605 is used for exhausting air, the vaporized liquid nitrogen in the freezing and preserving shell 7 is sent back into the cavity below the partition plate 5 for circulation, when the cell storing tube 11 is taken out, the fixing plate 806 is pulled outwards through the rotary handle 1001, the fixing plate 806 is driven by the sliding rod 804 to move, the push plate drives the fixed cell storage tube 11 to move, the cell storage tube 11 moves out of the circular through groove 13, and in the moving process of the supporting plate 801, the second ventilation tube 604 always sucks vaporized liquid nitrogen above the supporting plate 801 into the tube, so that the vaporized liquid nitrogen can be prevented from overflowing the cell freezing storage box 1 in the process of taking out the cell storage tube 11.

The application has the advantages that:

1. The application has reasonable structure, the fixed plate is pulled outwards by rotating the handle, the fixed plate drives the supporting plate to move through the sliding rod, the pushing plate drives the fixed cell storage tube to move, the cell storage tube moves out of the circular through groove, and the fan II always performs air draft in the moving process of the supporting plate, so that the air duct II always sucks vaporized liquid nitrogen above the supporting plate into the tube, thereby being convenient for avoiding the loss of cold air and the waste of liquid nitrogen caused by that the vaporized liquid nitrogen overflows the cell freezing box in a large amount in the process of taking out the cell storage tube.

2. The application has reasonable structure, the clamping block at the bottom of the cell storage tube is clamped in the clamping groove, the rotating handle is rotated, the connecting plate is driven to rotate by the rotating handle, the abutting rod is driven to rotate by the connecting rod, the abutting rod rotates and moves downwards to abut against the top of the cell storage tube, and the cell storage tube is conveniently and well fixed in the drawing structure.

3. The application has reasonable structure, and each freezing and storing shell is independently arranged and is not mutually interfered, so that the freezing and storing of other cell storing pipes can not be influenced when the single cell storing pipes are placed and taken.

The circuit, the electronic components and the modules are all in the prior art, and can be completely realized by a person skilled in the art, and needless to say, the protection of the application does not relate to the improvement of software and a method.

The above description is only of the preferred embodiments of the present application and is not intended to limit the present application, but various modifications and variations can be made to the present application by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application should be included in the protection scope of the present application.

Claims

1. The utility model provides a cell cryopreservation case, includes cell cryopreservation case (1) and cell storage tube (11), its characterized in that: still include connection structure (4), convulsions structure (6), pull structure (8) and support tight structure (10), fixed connection division board (5) on the inside wall of cell cryopreservation case (1), equidistance fixed connection cryopreservation case (7) on the top lateral wall of cell cryopreservation case (1), the bottom fixed connection of cryopreservation case (7) is on division board (5), be provided with convulsions structure (6) on cryopreservation case (7) and division board (5), be provided with pull structure (8) in cryopreservation case (7), be provided with on pull structure (8) and support tight structure (10), joint has cell storage tube (11) between pull structure (8) and the tight structure (10), bottom fixed connection joint piece (12) of cell storage tube (11), fixed connection fixed ring board (2) on the lateral wall of cell cryopreservation case (1), cell cryopreservation case (1) are through connection structure (4) connection top cap (3).

2. The cell cryopreservation box according to claim 1, wherein: the middle of the top of the cell freezing box (1) is circular and sunken downwards, and a threaded sleeve (9) is fixedly connected to the sunken part of the cell freezing box (1).

3. The cell cryopreservation box according to claim 1, wherein: connection structure (4) include carousel (401), connecting rod (402), turning block (403) and threaded rod (404), turning block (403) rotate and connect on the lateral wall of top cap (3), the bottom fixed connection threaded rod (404) of turning block (403), threaded rod (404) and screw sleeve (9) mutually support, the top fixed connection connecting rod (402) of turning block (403), the top fixed connection carousel (401) of connecting rod (402).

4. The cell cryopreservation box according to claim 1, wherein: the utility model provides a cell cryopreservation box, pull structure (8) includes layer board (801), fixed block (802), joint groove (803), slide bar (804), sealed pad (805) and fixed plate (806), slide bar (804) sliding connection is on the top lateral wall of cell cryopreservation box (1), bottom fixed connection layer board (801) of slide bar (804), layer board (801) sliding connection is in cryopreservation casing (7), fixed connection fixed block (802) on the top lateral wall of layer board (801), joint groove (803) have been seted up on the lateral wall of fixed block (802), top fixed connection fixed plate (806) of slide bar (804), fixed plate (806) are close to fixed connection sealed pad (805) on the lateral wall of cell cryopreservation box (1).

5. The cell cryopreservation box according to claim 4, wherein: the gasket (805) is made of rubber.

6. The cell cryopreservation box according to claim 4, wherein: the clamping groove (803) and the clamping block (12) are matched with each other.

7. The cell cryopreservation box according to claim 1, wherein: the abutting structure (10) comprises a rotating handle (1001), a connecting plate (1002) and an abutting rod (1003), wherein external threads are arranged on the outer side wall of the abutting rod (1003), the abutting rod (1003) is in threaded connection with the side wall of a fixed plate (806), the top of the abutting rod (1003) is fixedly connected with the connecting plate (1002), and the rotating handle (1001) is fixedly connected with the outer side wall of the top of the connecting plate (1002).

8. The cell cryopreservation box according to claim 1, wherein: the air draft structure (6) comprises an air draft tube (601), a fan I (602), an air draft tube I (603), an air draft tube II (604) and an air draft tube II (605), wherein the air draft tube (601) is fixedly connected to the side wall of a partition plate (5), the fan I (602) is fixedly connected to the inner side wall of the air draft tube (601), one ends of the air draft tube I (603) and the air draft tube II (604) are fixedly connected to the side wall of a freezing storage shell (7), the other end of the air draft tube I (603) is fixedly connected to the side wall of the air draft tube II (601), the other end of the air draft tube II (604) is fixedly connected to the side wall of the partition plate (5), and the other end of the air draft tube II (604) is circularly expanded, and the fan II (605) is fixedly connected to the inner side wall of the air draft tube II (604).

9. The cell cryopreservation tank of claim 8, wherein: the first ventilation pipe (603) and the second ventilation pipe (604) are respectively positioned at two sides of the freezing storage shell (7).

10. The cell cryopreservation box according to claim 1, wherein: the cell cryopreservation box is characterized in that circular through grooves (13) are formed in the top of the cell cryopreservation box (1) at equal intervals, the size of the circular through grooves (13) is matched with that of the cell storage tube (11) and that of the abutting rods (1003), the positions of the circular through grooves (13) and the positions of the cryopreservation shells (7) correspond to each other, a liquid inlet tube (15) is fixedly connected to the left side wall of the cell cryopreservation box (1), a round cover (14) is connected to the liquid inlet tube (15) in a threaded mode, and the liquid inlet tube (15) is located below the separation plate (5).