CN220724162U - Anti-interference type nucleic acid extraction equipment - Google Patents
Anti-interference type nucleic acid extraction equipment Download PDFInfo
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- CN220724162U CN220724162U CN202321065272.0U CN202321065272U CN220724162U CN 220724162 U CN220724162 U CN 220724162U CN 202321065272 U CN202321065272 U CN 202321065272U CN 220724162 U CN220724162 U CN 220724162U
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- clamping
- stirring
- pressing
- ring plate
- driving
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- 150000007523 nucleic acids Chemical class 0.000 title claims abstract description 19
- 102000039446 nucleic acids Human genes 0.000 title claims abstract description 19
- 108020004707 nucleic acids Proteins 0.000 title claims abstract description 19
- 238000000605 extraction Methods 0.000 title claims abstract description 15
- 238000012360 testing method Methods 0.000 claims abstract description 42
- 230000007246 mechanism Effects 0.000 claims abstract description 7
- 238000003756 stirring Methods 0.000 claims description 47
- 230000005540 biological transmission Effects 0.000 claims description 12
- 230000001681 protective effect Effects 0.000 claims description 11
- 230000000149 penetrating effect Effects 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 3
- 238000007789 sealing Methods 0.000 claims description 3
- 239000012780 transparent material Substances 0.000 claims description 3
- 238000013459 approach Methods 0.000 claims description 2
- 238000001514 detection method Methods 0.000 description 6
- 238000009434 installation Methods 0.000 description 5
- 239000000463 material Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000006037 cell lysis Effects 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000002380 cytological effect Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000010828 elution Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 230000000877 morphologic effect Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses an anti-interference type nucleic acid extraction device, which relates to the technical field of nucleic acid extraction devices, and comprises a base and a workbench arranged above the base, wherein the workbench and the base are fixedly connected through a plurality of supporting legs, a rotary ring plate is rotationally arranged at the middle position of the upper end of the workbench, the rotary ring plate is connected with a rotary driving part for driving the rotary ring plate to rotate, a plurality of mounting notches convenient for placing test tubes are arranged on the rotary ring plate, positioning slots corresponding to the bottoms of the test tubes are arranged at the bottoms of the mounting notches, and clamping mechanisms for tightly pressing two sides of the test tubes are arranged in the mounting notches where the positioning slots are arranged.
Description
Technical Field
The utility model relates to the technical field of nucleic acid extraction equipment, in particular to anti-interference nucleic acid extraction equipment.
Background
The nucleic acid detection is advanced biological detection at the molecular level, and has the remarkable advantages of higher sensitivity, specificity, no window period and the like compared with the traditional morphological detection, cytological detection, immunological detection and the like. The nucleic acid extraction process mainly comprises a plurality of processes including cell lysis, nucleic acid adsorption, washing and elution, wherein the test tube sample is required to be stirred in the process of processing, the existing stirring is in an open state and is easy to be influenced by external environment, the later detection is not facilitated, for example, patent publication No. CN214937394U discloses an automatic nucleic acid extractor, the device is in an open state when the sample in the test tube is stirred, in addition, the sample is in a normal state when the sample is clamped and positioned, and the later test tube removal and the earlier test tube installation are not facilitated.
Based on the above, an anti-interference nucleic acid extraction apparatus is provided, which can eliminate the drawbacks of the existing devices.
Disclosure of Invention
The utility model aims to provide an anti-interference nucleic acid extraction device, which aims to solve the problems in the background technology.
In order to achieve the above purpose, the present utility model provides the following technical solutions:
the utility model provides an anti-interference type nucleic acid extraction equipment, includes the base and sets up the workstation above it, connect fixedly through a plurality of landing legs between workstation and the base, workstation upper end intermediate position rotates and is equipped with a rotatory ring plate, and rotatory ring plate connection is used for driving its pivoted rotary drive spare, be equipped with a plurality of installation breach of being convenient for test tube and place on the rotatory ring plate, be equipped with the location slot corresponding with the test tube bottom in the installation breach, be equipped with the fixture that is used for sticis test tube both sides in the installation breach at location slot place, the workstation upper end still is equipped with the stirring structure that is used for stirring test tube inside liquid, the stirring structure includes with rotatory ring plate matched with protection casing, the protection casing both sides are equipped with and wear to put up the mouth with rotatory ring plate, this wear to put and be equipped with the sealing washer, the protection casing outside is connected with the workstation through the link, the protection casing upper end is equipped with the stirring piece.
Based on the technical scheme, the utility model also provides the following optional technical schemes:
in one alternative: the stirring piece is including setting up the fixed cover in the protecting cover upper end, fixed cover and protecting cover inner chamber intercommunication, fixed cover inside slip is equipped with a motor cabinet, the motor cabinet lower extreme is equipped with agitator motor, and agitator motor's output is equipped with a (mixing) shaft, the (mixing) shaft lower extreme is equipped with the stirring leaf.
In one alternative: the protective cover is made of transparent materials.
In one alternative: the rotary driving piece comprises a driven toothed ring arranged at the lower end of the rotary ring plate, the driven toothed ring is meshed with a driving gear, the driving gear is connected with a driving motor for driving the driving gear to rotate, and the driving gear is arranged at the upper end of the base.
In one alternative: the clamping mechanism comprises clamping plates arranged on two sides of the positioning slot, the clamping surfaces of the two clamping plates are V-shaped surfaces so as to clamp test tubes with different diameters, and the clamping plates are connected to form a pressing piece for driving the clamping plates to approach each other.
In one alternative: the pressing piece comprises clamping sliding blocks connected with the lower ends of clamping plates, sliding grooves corresponding to the clamping sliding blocks are formed in the bottoms of the mounting notches, the clamping sliding blocks are arranged on horizontally fixed wire cross rods in a sliding mode, the outer ends of the clamping sliding blocks are fixedly connected with the end portions of the wire cross rods through reset springs, a transmission rod is fixedly arranged on the outer side of each clamping sliding block, a clamping pressing wheel is rotatably arranged at the end portions of the transmission rods, a transmission cavity is formed in a rotating annular plate where the clamping pressing wheel is located, a rectangular sliding hole is formed in the surface of the transmission cavity, a horizontal sliding rod is arranged in the rectangular sliding hole in a sliding mode, guide pressing plates used for producing pushing force to the clamping pressing wheels are arranged at the inner ends of the horizontal sliding rods, the two guide pressing plates are of a splayed structure, and a pushing unit used for producing pushing force to the outer ends of the horizontal sliding rods is arranged on the surface of the workbench, and the pushing unit corresponds to the position of the stirring structure.
In one alternative: the pushing unit comprises a pressing roller which is rotatably arranged at the end part of the horizontal sliding rod, a pressing block corresponding to the pressing roller is arranged at the upper end of the workbench, the pressing surface of the pressing block is an arc-shaped surface, and guide inclined plates used for guiding the pressing roller are arranged at two ends of the pressing block.
Compared with the prior art, the utility model has the following beneficial effects:
1. the utility model is designed aiming at the existing needs, can pre-position the test tube, can trigger the compression only when the test tube is in the stirring position, is convenient for the displacement of the test tube in the early stage and the later stage, and in addition, the whole stirring process is in a relatively closed state, thereby reducing the risk of external interference, improving the reliability of samples and having strong practicability.
Drawings
Fig. 1 is a schematic view of the structure of the bottom part of the present utility model.
Fig. 2 is a schematic structural view of one side of the present utility model.
FIG. 3 is a schematic view of another embodiment of the present utility model.
Fig. 4 is a schematic structural view of the stirring element of the present utility model.
FIG. 5 is a schematic view of the structure of the clamping slider and return spring of the present utility model.
Reference numerals annotate: base 11, workstation 12, fixed cover 13, traction push rod 14, installation breach 15, rotatory crown 16, drive gear 17, driving motor 18, landing leg 19, press wheel 20, test tube 21, splint 22, horizontal slide bar 23, press block 24, guide swash plate 25, protection casing 26, stirring leaf 27, (mixing) shaft 28, motor cabinet 29, centre gripping slider 30, reset spring 31, transfer line 32, centre gripping pinch roller 33, guide clamp plate 34, wire horizontal pole 35.
Detailed Description
The present utility model will be described in further detail with reference to the drawings and examples, in order to make the objects, technical solutions and advantages of the present utility model more apparent.
In one embodiment, as shown in fig. 1-5, an anti-interference nucleic acid extracting apparatus includes a base 11 and a workbench 12 disposed above the base 11, the workbench 12 and the base 11 are connected and fixed by a plurality of legs 19, a rotating ring plate 16 is rotatably disposed at a middle position of an upper end of the workbench 12, the rotating ring plate 16 is connected with a rotating driving member for driving the rotating ring plate 16 to rotate, the rotating ring plate 16 can be powered by the rotating driving member, a plurality of mounting notches 15 for facilitating placement of test tubes 21 are disposed on the rotating ring plate 16, a positioning slot corresponding to a bottom of the test tubes 21 is disposed at an inner bottom of the mounting notch 15, a clamping mechanism for compacting two sides of the test tubes 21 is disposed in the mounting notch 15, a stirring structure for stirring internal liquid of the test tubes 21 is disposed at an upper end of the workbench 12, the stirring structure includes a protecting cover 26 matched with the rotating ring plate 16, two sides of the protecting cover 26 are provided with a penetrating opening matched with the rotating ring plate 16, a sealing ring is disposed at the penetrating position, an outer side of the protecting cover 26 is connected with the workbench 26 through a connecting frame, and the corresponding stirring member 26 is disposed at the upper end of the rotating ring plate 16, and when the stirring member is prevented from interfering with the sample, and the sample is disposed in a sealed state;
the stirring piece comprises a fixed sleeve 13 arranged at the upper end of a protective cover 26, the fixed sleeve 13 is communicated with the inner cavity of the protective cover 26, a motor seat 29 is slidably arranged in the fixed sleeve 13, a stirring motor is arranged at the lower end of the motor seat 29, a stirring shaft 28 is arranged at the output end of the stirring motor, and a stirring blade 27 is arranged at the lower end of the stirring shaft 28, so that the motor seat 29 can be driven to move downwards through a traction push rod 14, the stirring blade 27 stretches into the test tube 21, and stirring of a sample is completed;
in order to facilitate clear observation of the stirring condition, the protective cover 26 is made of transparent material, so that the stirring state of the sample can be observed through the protective cover 26;
the rotary driving piece comprises a driven toothed ring arranged at the lower end of the rotary ring plate 16, the driven toothed ring is meshed with a driving gear 17, the driving gear 17 is connected with a driving motor 18 for driving the rotary ring plate to rotate, the driving gear 17 is arranged at the upper end of the base 11, and the driving gear 17 is meshed with the driven toothed ring under the action of the driving motor 18, so that power is provided for the rotation of the rotary ring plate 16;
the clamping mechanism comprises clamping plates 22 arranged on two sides of the positioning slot, the clamping surfaces of the two clamping plates 22 are V-shaped surfaces so as to clamp test tubes 21 with different diameters, the clamping plates 22 are connected with compacting pieces used for driving the clamping plates to be close to each other, and when the test tubes 21 rotate to a stirring position, the compacting pieces trigger the clamping mechanism so as to finally fix the test tubes 21, so that the test tubes 21 are in a pre-positioning state at the material taking and discharging positions, and the material charging and the material taking are facilitated;
the clamping piece comprises clamping sliding blocks 30 connected with the lower ends of clamping plates 22, sliding grooves corresponding to the clamping sliding blocks 30 are formed in the bottoms of mounting notches 15, the clamping sliding blocks 30 are arranged on a horizontally fixed wire cross rod 35 in a sliding mode, the outer end of each clamping sliding block 30 is fixedly connected with the end portion of the wire cross rod 35 through a return spring 31, a transmission rod 32 is fixedly arranged on the outer side of each clamping sliding block 30, a clamping pressing wheel 33 is rotatably arranged at the end portion of each transmission rod 32, a transmission cavity is formed in the rotating annular plate 16 where the clamping pressing wheel 33 is located, a rectangular sliding hole is formed in the surface of each transmission cavity, a horizontal sliding rod 23 is slidably arranged in each rectangular sliding hole, guide pressing plates 34 used for generating pushing force for the clamping pressing wheels 33 are arranged at the inner ends of the horizontal sliding rods 23, two guide pressing plates 34 are of a splayed structure, pushing units used for generating pushing force for the outer ends of the horizontal sliding rods 23 are arranged on the surface of the workbench 12, and correspond to the position of a stirring structure, so that when the stirring position is achieved, the base 21 is in a locked state, a base pressing wheel 33 is provided, a rectangular sliding hole is formed in the stirring position, the stirring unit, the action is provided, the pressing plates are used for pushing the pressing plates, the guide pressing plates 34 and the two guide pressing plates 22 move towards the clamping plates 22, and the clamping pressing plates 22 are enabled to be clamped by the clamping pressing plates 22, and the two test tubes are enabled to be clamped to be close to the clamping plates 22, and can clamp the test tubes, and can be clamped by the clamping plates and can be clamped by the clamping plates and the test plates, and can are made by the test tube;
the pushing unit comprises a pressing roller 20 rotatably arranged at the end part of a horizontal sliding rod 23, a pressing block 24 corresponding to the pressing roller 20 is arranged at the upper end of the workbench 12, the pressing surface of the pressing block 24 is an arc surface, and guide inclined plates 25 for guiding the pressing roller 20 are arranged at the two ends of the pressing block 24, so that the pressing roller 20 can smoothly enter the pressing surface of the pressing block 24, and the pressing roller 20 can drive the horizontal sliding rod 23 to slide inwards under the action of the pressing surface;
the above-mentioned embodiment discloses a jam-proof nucleic acid extraction equipment, wherein, when in actual use, through placing test tube 21 in the positioning slot, accomplish the prepositioning, test tube 21 can be taken off easily this moment, rotate through driving rotatory crown plate 16 for test tube 21 sends into protection casing 26, when test tube 21 rotates to protection casing 26 position, the guide swash plate 25 of butt briquetting 24 both ends guide can make butt briquetting 20 get into the butt face of butt briquetting 24 smoothly, under the effect of butt briquetting, butt briquetting 20 can drive horizontal slide bar 23 to slide inwards, the guide clamp plate 34 of horizontal slide bar 23 tip moves towards splint 22, the inclined plane and the centre gripping pinch roller 33 interact of guide clamp plate 34 to make two centre gripping sliders 30 be close to, so two splint 22 then can accomplish the centre gripping to test tube 21, just so can drive motor cabinet 29 downwardly movable through traction push rod 14, make stirring leaf 27 stretch into this moment inside to sample, after the stirring is accomplished, rotate through driving rotatory crown plate 16, make the butt briquetting 21 that stirring is accomplished, the butt briquetting 21 that the stirring was shifted out, the butt briquetting 21 that is accomplished, the outside can be convenient for take out to take off the outside to the test tube 21 after the effect of butt briquetting 22, so can not be equipped with the outside to take off the elasticity layer 21 to the clamp plate 21, thereby the too is equipped with the outside to the test tube is pressed to the clamp 21.
The foregoing is merely specific embodiments of the disclosure, but the protection scope of the disclosure is not limited thereto, and any person skilled in the art can easily think about changes or substitutions within the technical scope of the disclosure, and it is intended to cover the scope of the disclosure. Therefore, the protection scope of the present disclosure shall be subject to the protection scope of the claims.
Claims (7)
1. An anti-interference type nucleic acid extraction device comprises a base (11) and a workbench (12) arranged above the base, wherein the workbench (12) is fixedly connected with the base (11) through a plurality of supporting legs (19), a rotary ring plate (16) is rotatably arranged in the middle of the upper end of the workbench (12), and the rotary ring plate (16) is connected with a rotary driving piece for driving the rotary ring plate to rotate;
the novel test tube stirring device is characterized in that a plurality of mounting notches (15) which are convenient for placing test tubes (21) are formed in the rotary ring plate (16), positioning slots corresponding to the bottoms of the test tubes (21) are formed in the bottoms of the mounting notches (15), clamping mechanisms which are used for tightly pressing two sides of the test tubes (21) are arranged in the mounting notches (15) where the positioning slots are located, a stirring structure which is used for stirring liquid inside the test tubes (21) is further arranged at the upper end of the workbench (12), the stirring structure comprises a protective cover (26) which is matched with the rotary ring plate (16), two sides of the protective cover (26) are provided with penetrating openings which are matched with the rotary ring plate (16), sealing rings are arranged at the penetrating openings, the outer sides of the protective cover (26) are connected with the workbench (12) through connecting frames, and stirring pieces are arranged at the upper end of the protective cover (26).
2. The anti-interference nucleic acid extraction device according to claim 1, wherein the stirring piece comprises a fixed sleeve (13) arranged at the upper end of the protective cover (26), the fixed sleeve (13) is communicated with the inner cavity of the protective cover (26), a motor seat (29) is slidably arranged in the fixed sleeve (13), a stirring motor is arranged at the lower end of the motor seat (29), a stirring shaft (28) is arranged at the output end of the stirring motor, and stirring blades (27) are arranged at the lower end of the stirring shaft (28).
3. The tamper-resistant nucleic acid extraction apparatus of claim 2, wherein the shield (26) is made of a transparent material.
4. The apparatus according to claim 1, wherein the rotary driving member comprises a driven toothed ring provided at a lower end of the rotary ring plate (16), the driven toothed ring being intermeshed with a driving gear (17), the driving gear (17) being connected to a driving motor (18) for driving the rotation thereof, the driving gear (17) being provided at an upper end of the base (11).
5. The apparatus according to claim 1, wherein the clamping mechanism comprises clamping plates (22) disposed on both sides of the positioning slot, the clamping surfaces of the two clamping plates (22) being V-shaped so as to clamp test tubes (21) of different diameters, the clamping plates (22) being connected to a presser for driving them to approach each other.
6. The anti-interference nucleic acid extraction apparatus according to claim 5, wherein the compressing member comprises clamping sliders (30) connected with the lower ends of the clamping plates (22), sliding grooves corresponding to the clamping sliders (30) are formed in the bottoms of the mounting notches (15), the clamping sliders (30) are slidably arranged on horizontally fixed wire cross rods (35), the outer ends of each clamping slider (30) are fixedly connected with the ends of the wire cross rods (35) through return springs (31), a transmission rod (32) is fixed on the outer side of each clamping slider (30), a clamping pressing wheel (33) is rotatably arranged at the end of each transmission rod (32), a transmission cavity is formed in a rotating annular plate (16) where the clamping pressing wheel (33) is located, a rectangular sliding hole is formed in the surface of each transmission cavity, a horizontal sliding rod (23) is slidably arranged in each rectangular sliding hole, a guide pressing plate (34) for pushing force generated by the clamping pressing wheel (33) is arranged at the inner end of each horizontal sliding rod, two guide pressing plates (34) are in a splayed structure, a pushing table (12) is provided with pushing units for pushing the surface of each pushing unit to generate pushing force corresponding to the outer ends of the sliding rods.
7. The apparatus according to claim 6, wherein the pushing unit comprises a pressing roller (20) rotatably provided at an end of a horizontal slide bar (23), a pressing block (24) corresponding to the pressing roller (20) is provided at an upper end of the table (12), the pressing surface of the pressing block (24) is an arc surface, and guide inclined plates (25) for guiding the pressing roller (20) are provided at both ends of the pressing block (24).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321065272.0U CN220724162U (en) | 2023-05-05 | 2023-05-05 | Anti-interference type nucleic acid extraction equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321065272.0U CN220724162U (en) | 2023-05-05 | 2023-05-05 | Anti-interference type nucleic acid extraction equipment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220724162U true CN220724162U (en) | 2024-04-05 |
Family
ID=90499109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321065272.0U Active CN220724162U (en) | 2023-05-05 | 2023-05-05 | Anti-interference type nucleic acid extraction equipment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220724162U (en) |
-
2023
- 2023-05-05 CN CN202321065272.0U patent/CN220724162U/en active Active
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