CN220677175U - Leak-proof negative pressure protection structure and isolator - Google Patents

Leak-proof negative pressure protection structure and isolator Download PDF

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Publication number
CN220677175U
CN220677175U CN202321981033.XU CN202321981033U CN220677175U CN 220677175 U CN220677175 U CN 220677175U CN 202321981033 U CN202321981033 U CN 202321981033U CN 220677175 U CN220677175 U CN 220677175U
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China
Prior art keywords
negative pressure
filter
pressure protection
cavity
protection structure
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CN202321981033.XU
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Chinese (zh)
Inventor
牟华伟
江培
万勋
贺国伦
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Shanghai Sensong Biotechnology Co ltd
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Shanghai Sensong Biotechnology Co ltd
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Abstract

The application provides a leak-proof negative pressure protection structure and an isolator. The anti-leakage negative pressure protection structure comprises a cavity (1). The filter (2) is used for connecting in cavity (1), filter (2) can filter gas and will be filtered gas and send into in cavity (1), frame (20) of filter (2) with be formed with negative pressure protection space (3) between cavity (1), negative pressure protection space (3) are used for connecting negative pressure production equipment to negative pressure protection space (3) produce the negative pressure, in order to prevent unfiltered gas from follow frame (20) with get into between cavity (1). The application provides an isolator includes above-mentioned leak protection negative pressure protection structure.

Description

Leak-proof negative pressure protection structure and isolator
Technical Field
The application relates to the field of isolators in the pharmaceutical industry, in particular to a leakage-proof negative pressure protection structure and an isolator.
Background
The existing sterile isolator is provided with a filter, and the sealing performance between the filter and the isolator cavity is guaranteed by the sealing ring made of silicone rubber materials of the frame of the filter, so that leakage is prevented. However, the aging failure of the seal ring itself can lead to leakage and contamination.
The publication No. CN202983412U discloses a high-efficiency air filter device for an isolator, which comprises an isolator, a cavity communicated with the upper part of the isolator, and a first high-efficiency filter arranged in the cavity. The cavity is cylindrical, the first high-efficiency filter is cylindrical, and a sealing ring embedded on the inner wall of the cavity is arranged between the first high-efficiency filter and the cavity. Likewise, when its seal ring ages, its isolator may leak.
Disclosure of Invention
In order to ameliorate or solve at least one of the problems mentioned in the background, the present application provides a leak-proof negative pressure protection structure and isolator.
The leak-proof negative pressure protection structure provided by the embodiment of the application comprises a cavity, a filter is used for being connected with the cavity,
the filter can filter gas and send the filtered gas into the cavity, a negative pressure protection space is formed between the frame of the filter and the cavity, and the negative pressure protection space is used for being connected with negative pressure generating equipment so as to generate negative pressure in the negative pressure protection space, so that unfiltered gas is prevented from entering the cavity from the position between the frame and the cavity.
In at least one embodiment, the cavity comprises:
the top wall is provided with an air inlet, the edge of the air inlet surface of the filter is abutted against the top wall, and the air inlet surface of the filter is aligned to the air inlet;
the support plate is provided with an air outlet, the edge of the air exhaust surface of the filter is abutted against the support plate, the air exhaust surface of the filter is aligned with the air outlet,
a side wall, the support plate being connected to the side wall to secure the filter between the top wall and the support plate,
the top wall, the support plate, the side walls and the rim of the filter form the negative pressure protection space.
In at least one embodiment, the cavity further comprises a connecting plate extending inwards from the side wall, the negative pressure protection structure further comprises a screw and a nut,
one end of the screw rod is connected with the connecting plate, the other end of the screw rod penetrates through the supporting plate, and the nut is used for fixing the supporting plate on the screw rod.
In at least one embodiment, an upward annular sealing plate is arranged on the supporting plate, an annular sealing strip is arranged on the lower side of the connecting plate, the annular sealing strip is provided with a downward notch, and the annular sealing plate is inserted into the notch.
In at least one embodiment, a first sealing ring is arranged at the position of the filter, which is in contact with the top wall, and a second sealing ring is arranged at the position of the filter, which is in contact with the supporting plate.
In at least one embodiment, a downwardly extending stop plate is provided on the top wall for limiting the position of the filter such that the air inlet face of the filter is aligned with the air inlet of the top wall.
In at least one embodiment, a negative pressure pipe is provided on the support plate, which is communicated with the negative pressure protection space, and the negative pressure protection space is connected to the negative pressure generating device through the negative pressure pipe.
The isolator provided by the embodiment of the application comprises the anti-leakage negative pressure protection structure.
In at least one embodiment, the separator comprises a filter as described above.
According to the filter, the negative pressure protection space is arranged between the frame of the filter and the cavity of the isolator, and unfiltered air is prevented from entering the cavity from between the filter and the cavity in an active suction mode. The problems of leakage and pollution possibly generated after the ageing and invalidation of the traditional sealing structure such as the sealing ring are solved.
Drawings
Fig. 1 shows a schematic structural view of a leak-proof negative pressure protection structure according to an embodiment of the present application.
Fig. 2 shows a partial enlarged view of the leak-proof negative pressure protection structure in fig. 1.
Description of the reference numerals
1, a cavity; 11 top wall; 111 air inlets; 112 limiting plates; a 12 support plate; 121 exhaust outlet; 122 annular sealing plates; 13 side walls; 14, connecting a plate; 141 annular sealing strips;
2, a filter; 20 frames; 21 air inlet surfaces; 22 exhaust surfaces; 23 a first seal ring; 24 a second seal ring;
3. a negative pressure protection space;
4. a screw;
5. a nut;
6. negative pressure pipeline.
Detailed Description
Exemplary embodiments of the present application are described below with reference to the accompanying drawings. It should be understood that these specific descriptions are merely illustrative of how one skilled in the art may practice the present application and are not intended to be exhaustive of all of the possible ways of practicing the present application nor to limit the scope of the present application.
In the description of the present application, it is to be understood that the terms: the directions or positional relationships indicated by the center, the longitudinal direction, the transverse direction, the length, the width, the thickness, the upper, lower, front, rear, left, right, vertical, horizontal, top, bottom, inner, outer, clockwise, counterclockwise, etc. are those based on the drawings, which are merely for convenience of description of the present application and thus are not to be construed as limitations of the present application.
Furthermore, the term: first, second, etc. are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of features shown. In the description of the present application, unless explicitly specified and defined otherwise, the terms: mounting, connecting, etc. are to be construed broadly and the specific meaning of the terms herein described will be understood by those skilled in the art in view of the specific circumstances.
Referring to fig. 1 and 2, embodiments of the present application provide a leak-proof negative pressure protection structure and an isolator.
The negative pressure protection structure for preventing leakage can be a component structure of the isolator. A filter 2 may be provided in the separator. The leak-proof negative pressure protection structure may comprise a chamber 1, and a filter 2 is connected to the chamber 1. The filter 2 is capable of filtering and feeding gas into the chamber 1.
A negative pressure protection space 3 is formed between the frame 20 of the filter 2 and the cavity 1, the negative pressure protection space 3 is used for being connected with a negative pressure generating device, and negative pressure is generated in the negative pressure protection space 3 through active suction of the negative pressure generating device so as to prevent unfiltered gas from entering the cavity 1 from between the frame 20 and the cavity 1. Through setting up negative pressure protection space 3 and initiatively sucking between filter 2 and the cavity 1 that probably leak, avoided unfiltered unclean gas to get into the aseptic operation area in the cavity, effectively controlled and revealed, pollution risk. Illustratively, the negative pressure generating device may be an air pump, a negative pressure blower, or the like. It should be appreciated that the rim 20 may be a frame structure of the filter 2, such as a structure of the side walls, top surface and bottom surface thereof that does not participate in the filtering.
Further, referring to fig. 2, the cavity 1 may include a top wall 11, a support plate 12, and side walls 13. The top wall 11 is provided with an air inlet 111, and the edge of the air inlet surface 21 (top surface in fig. 2) of the filter 2 abuts against the top wall 11, so that the air inlet surface 21 of the filter 2 is aligned with the air inlet 111. The support plate 12 is provided with an air outlet 121, and the edge of the air exhaust surface 22 (the bottom surface in fig. 2) of the filter 2 abuts against the support plate 12, so that the air exhaust surface 22 of the filter 2 is aligned with the air outlet 121. The support plate 12 is connected to the side walls 13 to secure the filter 2 between the top wall 11 and the support plate 12.
The top wall 11, the support plate 12, the side walls 13 and the rim 20 of the filter 2 form the above-mentioned sub-pressure protection space 3. Compared with the prior art that the side wall of the filter is connected with the side wall of the cavity, the air inlet surface 21 and the air exhaust surface 22 of the filter 2 are respectively connected with the top wall 11 and the supporting plate 12, so that the negative pressure protection space 3 is positioned on the side surface of the filter 2, and the filter is simple in structure and easy to realize.
Further, the cavity 1 further comprises a connecting plate 14 extending inwards from the side wall 13, and the negative pressure protection structure can further comprise a screw 4 and a nut 5. One end of the screw 4 (upper end of fig. 2) is connected to the connection plate 14, for example, one end of the screw 4 is welded to the connection plate 14. The other end (lower end in fig. 2) of the screw 4 passes through the support plate 12, and the nut 5 fixes the support plate 12 to the screw 4. The nut 5 may be a cap nut that covers the end of the stud 4 to reduce contact between the interior of the cavity 1 and the threads on the screw 4 for greater safety.
Further, an upward annular sealing plate 122 is arranged on the supporting plate 12, an annular sealing strip 141 is arranged on the lower side of the connecting plate 14, the annular sealing strip 141 is provided with a downward notch, and the annular sealing plate 122 is inserted into the notch to realize sealing.
Further, a first sealing ring 23 is arranged between the filter 2 and the top wall 11, and a second sealing ring 24 is arranged between the filter 2 and the supporting plate 12, so that sealing is realized. It is understood that this includes the case where the first seal ring 23 is previously provided or formed on the top surface of the top wall 11 or the filter 2, and the case where the second seal ring 24 is previously provided or formed on the bottom surface of the support plate 12 or the filter 2.
It will be appreciated that even if the first seal ring 23 and the second seal ring 24 fail due to aging or the like, the leaked gas is pumped away from the negative pressure protection space 3, so that the unfiltered gas is prevented from polluting the inner space of the cavity 1.
Further, a limiting plate 112 extending downwards is arranged on the top wall 11, and the limiting plate 112 is used for limiting the position of the filter 2, so that the air inlet surface 21 of the filter 2 is aligned with the air inlet 111 of the top wall 11. The limiting plate 12 may be a plurality of block-shaped limiting plates; the limiting plate 12 may be an annular limiting plate with a rectangular groove formed on the inner side of the top wall 11.
Further, the support plate 12 is provided with a negative pressure pipe 6 communicated with the negative pressure protecting space 3, and the negative pressure protecting space 3 is connected to a negative pressure generating device through the negative pressure pipe 6. It will be appreciated that the arrows at the negative pressure conduit 6 in fig. 2 represent the direction of gas flow in the conduit.
The separator provided herein may include a negative pressure protection structure that is leak-proof as described above, and the filter 2. The filter 2 is mounted in a negative pressure protection structure. It will be appreciated that the top wall 11 may be the top structure of the negative pressure protection structure shown in fig. 2, but does not necessarily represent the top structure of the separator.
In another embodiment of the present application, the separator may include a negative pressure protection structure that is leak-proof as described above, without including the filter 2 described above.
While the foregoing is directed to the preferred embodiments of the present application, it will be appreciated by those skilled in the art that changes and modifications may be made without departing from the principles of the present application, such changes and modifications are to be considered as within the scope of the present application.

Claims (9)

1. A leak-proof negative pressure protection structure is characterized by comprising a cavity, a filter connected with the cavity,
the filter can filter gas and send the filtered gas into the cavity, a negative pressure protection space is formed between the frame of the filter and the cavity, and the negative pressure protection space is used for being connected with negative pressure generating equipment so as to generate negative pressure in the negative pressure protection space, so that unfiltered gas is prevented from entering the cavity from the position between the frame and the cavity.
2. The leak-proof negative pressure protection structure of claim 1, wherein the cavity comprises:
the top wall is provided with an air inlet, the edge of the air inlet surface of the filter is abutted against the top wall, and the air inlet surface of the filter is aligned to the air inlet;
the support plate is provided with an air outlet, the edge of the air exhaust surface of the filter is abutted against the support plate, the air exhaust surface of the filter is aligned with the air outlet,
a side wall, the support plate being connected to the side wall to secure the filter between the top wall and the support plate,
the top wall, the support plate, the side walls and the rim of the filter form the negative pressure protection space.
3. The leakage prevention negative pressure protection structure according to claim 2, wherein said cavity further comprises a connection plate protruding inward from said side wall, said negative pressure protection structure further comprising a screw, a nut,
one end of the screw rod is connected with the connecting plate, the other end of the screw rod penetrates through the supporting plate, and the nut is used for fixing the supporting plate on the screw rod.
4. A leak-proof negative pressure protection structure as claimed in claim 3, wherein an upward-facing annular sealing plate is provided on the support plate, an annular sealing strip is provided on the underside of the connection plate, the annular sealing strip has a downward-facing notch, and the annular sealing plate is inserted into the notch.
5. The leakage-proof negative pressure protection structure according to claim 2, wherein a first sealing ring is provided at a portion of the filter abutting against the top wall, and a second sealing ring is provided at a portion of the filter abutting against the support plate.
6. The leakage-proof negative pressure protection structure according to claim 2, wherein a limiting plate extending downward is provided on the top wall, and the limiting plate is used for limiting the position of the filter, so that the air inlet surface of the filter is aligned with the air inlet of the top wall.
7. The leak-proof negative pressure protection structure according to claim 2, wherein a negative pressure pipe is provided on the support plate, which communicates with the negative pressure protection space, the negative pressure protection space being connected to the negative pressure generating apparatus through the negative pressure pipe.
8. An isolator comprising the leak-proof negative pressure protection structure according to any one of claims 1 to 7.
9. The isolator of claim 8, further comprising the filter.
CN202321981033.XU 2023-07-26 2023-07-26 Leak-proof negative pressure protection structure and isolator Active CN220677175U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202321981033.XU CN220677175U (en) 2023-07-26 2023-07-26 Leak-proof negative pressure protection structure and isolator

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202321981033.XU CN220677175U (en) 2023-07-26 2023-07-26 Leak-proof negative pressure protection structure and isolator

Publications (1)

Publication Number Publication Date
CN220677175U true CN220677175U (en) 2024-03-29

Family

ID=90404879

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202321981033.XU Active CN220677175U (en) 2023-07-26 2023-07-26 Leak-proof negative pressure protection structure and isolator

Country Status (1)

Country Link
CN (1) CN220677175U (en)

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