CN212633789U - Negative pressure protection structure for sterile toxic isolator and sterile toxic isolator - Google Patents
Negative pressure protection structure for sterile toxic isolator and sterile toxic isolator Download PDFInfo
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- CN212633789U CN212633789U CN202021311971.5U CN202021311971U CN212633789U CN 212633789 U CN212633789 U CN 212633789U CN 202021311971 U CN202021311971 U CN 202021311971U CN 212633789 U CN212633789 U CN 212633789U
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Abstract
A negative pressure protection structure for a sterile toxic isolator and the sterile toxic isolator are provided. The isolator comprises a cavity (10) defined by a plurality of cavity walls and at least one sensing or connecting element sealingly mounted to the cavity walls. The negative pressure protection structure includes: a housing (52) for mounting to the chamber wall such that the connection of the at least one detection or connection element to the chamber wall is located within the housing (52); and a negative pressure suction port (51) which is provided in the housing (52) and sucks the gas and/or particles in the housing (52) to form a negative pressure in the housing (52). Through the negative pressure protection structure for the sterile toxic isolator, the suction and discharge of trace toxic gas and/or particle leakage at the joint of the detection or connection element and the cavity wall can be realized, and further, the operation personnel can be protected.
Description
Technical Field
The application relates to a negative pressure protection structure for a sterile toxic isolator and the sterile toxic isolator.
Background
In the development of anticancer drugs, for example, it is necessary to isolate toxic materials using an isolator. The design of aseptic poisonous isolator generally adopts the pressure-fired to guarantee the sterility of product, takes out negative pressure in the twinkling of an eye after detecting to have the leak point and protects operating personnel. Based on the micro-positive pressure design, the system is undetectable if the detection in the isolator, the connection of the connection elements, has a small amount of leakage below the acceptable leakage rate.
SUMMERY OF THE UTILITY MODEL
In order to better protect the safety of operators and solve the problem of micro leakage, the application provides a negative pressure protection structure for a sterile toxic isolator and the sterile toxic isolator, and the main risk point of leakage is considered to be at the joint of a detection element and a connecting element.
There is provided a negative pressure protection arrangement for a sterile toxic isolator, the isolator comprising a cavity defined by a plurality of cavity walls and at least one sensing or connecting element sealingly mounted to the cavity walls,
the negative pressure protection structure includes:
a housing for mounting to the chamber wall such that the connection of the at least one sensing or connecting element to the chamber wall is located within the housing; and
and the negative pressure sucking port is arranged on the cover shell and is used for sucking the gas and/or the particles in the cover shell to form negative pressure in the cover shell.
In at least one embodiment, the enclosure includes an air inlet.
In at least one embodiment, the negative pressure protection structure further comprises an air filter or one-way valve mounted to the housing at the air inlet.
In at least one embodiment, the negative pressure protection structure further comprises a suction device for connecting to the negative pressure suction port to create negative pressure in the enclosure.
In at least one embodiment, the enclosure is formed as a closed structure.
In at least one embodiment, the at least one detection or connection element comprises one or more of the following elements: anemometer, temperature and humidity sensor, differential pressure transducer joint.
In at least one embodiment, the negative pressure protection structure further comprises a housing gasket, via which the housing is sealingly mounted to the chamber wall.
In at least one embodiment, the housing is a sheet metal housing on which one or more of the following elements are mounted: a glan head and a quick-insertion type air pipe joint.
Providing a sterile, toxic isolator, the isolator comprising:
a cavity defined by a plurality of cavity walls; and
at least one sensing or connecting element sealingly mounted to the chamber wall and extending into the chamber body;
wherein, the isolator still includes according to this application aseptic toxic negative pressure protection architecture for isolator.
In at least one embodiment, the isolator further comprises a mounting plate and a cavity seal, the at least one sensing or connecting element being sealingly mounted to the cavity wall via the mounting plate and the cavity seal.
Through aseptic toxic negative pressure protection structure for isolator of this application, can realize getting rid of the suction that detects or connecting element and chamber wall junction trace toxic gas and/or granule leaked, and then protect operating personnel. A sterile toxic isolator for suction venting of trace leaks of toxic gases and/or particles is also provided.
Drawings
Fig. 1 shows a schematic structural view of a sterile toxic isolator according to an embodiment of the present application.
Fig. 2 shows a perspective view of the sterile toxic isolator of fig. 1.
Description of the reference numerals
10 cavity 20 anemometer 30 temperature and humidity sensor 40 differential pressure transducer connector 51 draws negative pressure port 52 housing 53 air filter 54 housing seal 60 mounting plate 70 cavity seal.
Detailed Description
Exemplary embodiments of the present application are described below with reference to the accompanying drawings. It should be understood that the detailed description is only intended to teach one skilled in the art how to practice the present application, and is not intended to be exhaustive or to limit the scope of the application.
As shown in fig. 1 and 2, the present application provides a sterile toxic isolator (hereinafter, sometimes simply referred to as "isolator") and a negative pressure protection structure for the sterile toxic isolator (hereinafter, sometimes simply referred to as "negative pressure protection structure"). The isolator comprises a chamber 10 defined by a plurality of chamber walls and at least one sensing or connecting element sealingly mounted to one of the chamber walls.
This negative pressure protection architecture includes: a housing 52 for mounting to one of the chamber walls such that the connection of the at least one sensing or connecting element to the chamber wall is located within the housing 52; and a negative pressure suction port 51 provided in the casing 52 for sucking the gas and/or particles in the casing 52 to form a negative pressure in the casing 52.
The at least one detection or connection element may comprise one or more of the following elements: anemometer 20, temperature and humidity sensor 30, differential pressure transducer joint 40.
The isolator may further comprise a mounting plate 60 and a cavity seal 70, and the at least one sensing or connecting element may be sealingly mounted to the cavity wall via the mounting plate 60 and the cavity seal 70 using, for example, bolts, such that at least a functional portion of the at least one sensing or connecting element protrudes into the cavity 10.
The housing 52 may include an air inlet. The negative pressure protection structure may further include an air filter 53 or a check valve mounted to the housing 52 at the air inlet. The air filter 53 serves to absorb or filter toxic gases and/or particles that may leak from the chamber 10 to avoid the toxic gases and/or particles from causing a hazard to workers around the isolator. The air filter 53 may be replaced by a one-way valve configured to allow gas to enter the enclosure 52 while preventing gas from flowing from within the enclosure 52 to outside the enclosure 52.
The negative pressure protection structure may further comprise a suction device for connecting to the negative pressure suction port 51 to create a negative pressure in the housing 52. The suction device may be, for example, a vacuum pump or a suction fan.
Optionally, the negative pressure protection structure may further comprise a housing gasket 54, and the housing 52 may be sealingly mounted to the chamber wall via the housing gasket 54 using, for example, bolts, such that the housing 52 and the at least one detection or connection element are located on both sides of the chamber wall, i.e. the housing 52 is located outside the chamber 10.
The housing 52 may be a sheet metal housing. The sheet metal housing can be provided with a gland head and/or a quick-insertion type air pipe joint and other joints. It can be understood that the housing is not limited to a sheet metal housing, and the material and processing technique thereof may be other materials or techniques as long as the tightness of the housing is not affected by the reaction with the leaked trace gas and/or particles.
It is understood that the housing 52 is formed as a closed structure except for the suction port 51, the intake port, and the above-described joint.
It will be appreciated that the negative pressure created within the enclosure 52 may be near atmospheric pressure or a particular range of negative pressures, so long as the negative pressure is not positive and does not leak gas and/or particles within the enclosure 52.
It will be appreciated that where an air inlet is provided in the casing 52, the above-described suction device may be operated continuously to maintain the negative pressure in the casing 52. Alternatively, no air inlet may be provided in the casing 52, so that the extraction device may even be operated intermittently, only so far as it is possible to maintain a negative pressure in the casing 52.
Alternatively, a pressure sensor may be provided in the enclosure 52 to measure the air pressure inside the enclosure. The pressure sensor may be connected to a control system to realize automatic control of the pumping device, that is, the measured data of the pressure sensor may be used to control the operation or non-operation and operating state of the pumping device, so that the air pressure in the casing 52 meets the design requirements.
Optionally, the isolator top has an opening and the casing 52 is mounted to the isolator side walls.
In the negative pressure protection structure for the sterile toxic isolator, negative pressure is formed in the housing by the suction device, the air inlet and the like, so that the trace toxic gas and/or particle leakage at the joint of the detection or connection element and the cavity wall can be sucked and removed, and further operators are protected. The detection or connection element can be hermetically arranged on the cavity wall through the mounting plate and the sealing gasket, and the sealing performance of the isolator is further improved.
While the present application has been described with reference to exemplary embodiments, it is to be understood that the present application is not limited to the disclosed exemplary embodiments. Various modifications and alterations of the above-described embodiments may be made by those skilled in the art in light of the teachings of this application without departing from the scope thereof.
Claims (10)
1. A negative pressure protection arrangement for a sterile toxic isolator comprising a chamber body (10) defined by a plurality of chamber walls and at least one sensing or connecting element sealingly mounted to the chamber walls, characterized in that,
the negative pressure protection structure includes:
a housing (52) for mounting to the chamber wall such that the connection of the at least one detection or connection element to the chamber wall is located within the housing (52); and
a negative pressure suction port (51) arranged on the housing (52) for sucking the gas and/or particles in the housing (52) to form negative pressure in the housing (52).
2. The negative pressure protection structure for the sterile toxic isolator according to claim 1,
the housing (52) includes an air inlet.
3. The negative pressure protection structure for the sterile toxic isolator according to claim 2,
the negative pressure protection arrangement further comprises an air filter (53) or a one-way valve mounted to the housing (52) at the air inlet.
4. The negative pressure protection structure for the sterile toxic isolator according to claim 1,
the negative pressure protection structure further comprises a suction device for connecting to the negative pressure suction port (51) to form a negative pressure in the casing (52).
5. The negative pressure protection structure for the sterile toxic isolator according to claim 1,
the casing (52) is formed as a closed structure.
6. The negative pressure protection structure for a sterile toxic isolator according to claim 1, wherein the at least one detection or connection element comprises one or more of the following elements: an anemometer (20), a temperature and humidity sensor (30) and a differential pressure transmitter joint (40).
7. The negative pressure protection structure for the sterile toxic isolator according to claim 1,
the negative pressure protection structure further comprises a housing gasket (54), and the housing (52) is hermetically mounted to the cavity wall through the housing gasket (54).
8. The negative pressure protection structure for the sterile toxic isolator according to claim 1,
the housing (52) is a sheet metal housing on which one or more of the following elements are mounted: a glan head and a quick-insertion type air pipe joint.
9. An aseptic toxic isolator, the isolator comprising:
a cavity (10) defined by a plurality of cavity walls; and
at least one detection or connection element sealingly mounted to the chamber wall and extending into the chamber body (10);
the isolator is characterized by further comprising a negative pressure protection structure for the sterile toxic isolator, which is defined in any one of claims 1 to 8.
10. The isolator as in claim 9,
the isolator further comprises a mounting plate (60) and a cavity seal (70), the at least one sensing or connecting element being sealingly mounted to the cavity wall via the mounting plate (60) and the cavity seal (70).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021311971.5U CN212633789U (en) | 2020-07-07 | 2020-07-07 | Negative pressure protection structure for sterile toxic isolator and sterile toxic isolator |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021311971.5U CN212633789U (en) | 2020-07-07 | 2020-07-07 | Negative pressure protection structure for sterile toxic isolator and sterile toxic isolator |
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| CN212633789U true CN212633789U (en) | 2021-03-02 |
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| CN202021311971.5U Active CN212633789U (en) | 2020-07-07 | 2020-07-07 | Negative pressure protection structure for sterile toxic isolator and sterile toxic isolator |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111760869A (en) * | 2020-07-07 | 2020-10-13 | 上海森松制药设备工程有限公司 | Negative pressure protection structure for sterile toxic isolator and sterile toxic isolator |
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2020
- 2020-07-07 CN CN202021311971.5U patent/CN212633789U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111760869A (en) * | 2020-07-07 | 2020-10-13 | 上海森松制药设备工程有限公司 | Negative pressure protection structure for sterile toxic isolator and sterile toxic isolator |
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