CN220609183U

CN220609183U - Chromatographic separation device

Info

Publication number: CN220609183U
Application number: CN202321977855.0U
Authority: CN
Inventors: 王树民; 王汉中; 潘月平
Original assignee: Bainuo Chuangrei Wenzhou Biotechnology Co ltd
Current assignee: Bainuo Chuangrei Wenzhou Biotechnology Co ltd
Priority date: 2023-07-26
Filing date: 2023-07-26
Publication date: 2024-03-19
Anticipated expiration: 2033-07-26

Abstract

The utility model discloses a chromatographic separation device, which belongs to the technical field of chromatographic separation and comprises a base and an upright post fixedly arranged above the base, wherein a chromatographic tube supporting piece is arranged on the upright post, the chromatographic tube supporting piece comprises a sleeve which slides with the upright post and a four-corner frame which is fixedly arranged on the sleeve, a movable piece is arranged behind the four-corner frame, and a clamping part is formed by combining the movable piece with each corner of the four-corner frame. Compared with the prior art, the positioning mechanism in the application can realize the clamping of the chromatographic tube by opening the clamping part only by using one hand to operate the toggle rod, and can enable the other chromatographic tube to be in butt joint with the last chromatographic tube and rotate to enable the other chromatographic tube and the last chromatographic tube to be in threaded connection and fixed.

Description

Chromatographic separation device

Technical Field

The utility model relates to the technical field of chromatographic separation, in particular to a chromatographic separation device.

Background

Chromatography is a separation technique established by utilizing the physical and chemical properties of different substances, and in the process of separating substances by chromatography, a chromatographic separation device is required to complete the separation of the substances.

The chromatographic separation device in the prior art comprises an air compression pump for compressing air, a mobile phase management assembly and a chromatographic column. Controllable dripping of the mobile phase is realized in the mobile phase management component. When in use, air enters the mobile phase management assembly and the chromatographic column through the pressure interface by pressure regulation and pressure measurement of the buffer bottle, and is conducted to the mobile phase to drive the mobile phase to elute at a high speed. The installation mode is that a chromatographic column, a pressure interface component (buffer bottle) and a mobile phase management component are arranged in sequence from bottom to top. In the prior published patent (publication number: CN 218900907U), chromatographic separation devices are realized by butting chromatographic tubes together in a threaded manner, so that chromatographic systems with different lengths of mobile phases can be changed, and meanwhile, stationary phases can be filled and cleaned in a segmented manner.

However, in the above patent, when different chromatographic tubes are abutted, a gravity chromatographic column is required to be used, in the prior art, the chromatographic tubes are fixed by a fixing rod, two connecting seats which are vertically distributed and a clamping piece fixedly connected with the connecting seats, and the fixing mode is troublesome, and the threaded connection between the chromatographic columns is required to be completed while the fixing is required to be completed. The use is inconvenient.

Disclosure of Invention

The present utility model is directed to a chromatographic separation device, which solves the problems of the prior art that the screw connection between chromatographic tubes needs to be considered while the fixation is completed.

In order to achieve the above purpose, the present utility model provides the following technical solutions:

the utility model provides a chromatographic separation device, includes the base and fixed mounting is in the stand of base top, be provided with chromatographic tube support piece on the stand, chromatographic tube support piece include with stand gliding sleeve pipe, the four corners frame of fixed mounting on the sleeve pipe already, the rear of four corners frame is provided with the moving part, the moving part with make up into a clamping part between every angle of four corners frame.

As still further aspects of the utility model: the movable parts are hinged to the back of the four-corner frame through rotating shafts, reset springs are arranged between the two movable parts in the same group, and a poking rod is fixedly arranged at the movable ends of the movable parts.

As still further aspects of the utility model: the movable part is fixedly provided with positioning columns at the movable end, and the four corners of the four-corner frame are also provided with positioning columns.

As still further aspects of the utility model: wherein, the reference column is made of rubber material.

As still further aspects of the utility model: wherein, the reference column is set up to cylindrical shape.

As still further aspects of the utility model: the clamping devices comprise sliding pieces, supporting arms are fixedly arranged on two sides of the sliding pieces, and clamping rings are fixedly arranged on end faces, far away from the sliding pieces, of the supporting arms.

As still further aspects of the utility model: wherein, the clamping piece and the sleeve are both provided with positioning bolts.

Compared with the prior art, the utility model has the beneficial effects that:

the chromatographic device in this embodiment realizes pressing (even its mutual motion) to the poking rod through two fingers of a hand respectively control poking rod, and the moving part can be close to each other and extrude reset spring this moment, and reset spring has elastic potential energy, and the clamping part that exists between moving part and the four corners frame is opened, can put into the clamping part with the chromatographic tube, then releases poking rod, under the elastic potential energy effect that reset spring has, can apply reverse power to the moving part and carry out the centre gripping location to the chromatographic tube. The fixing effect is realized. Compared with the prior art, the positioning mechanism in the application can realize the clamping of the chromatographic tube by opening the clamping part only by using one hand to operate the toggle rod, and can enable the other chromatographic tube to be in butt joint with the last chromatographic tube and rotate to enable the other chromatographic tube and the last chromatographic tube to be in threaded connection and fixed.

Drawings

FIG. 1 is a schematic diagram of the overall structure of the present utility model;

FIG. 2 is a schematic view of the back of a chromatographic tube support according to the present utility model;

FIG. 3 is a schematic view of a four-corner frame structure according to the present utility model;

FIG. 4 is an enlarged schematic view of the structure A of FIG. 3 according to the present utility model;

FIG. 5 is a schematic diagram showing the connection of the chromatographic apparatus of the utility model.

The correspondence between the reference numerals and the component names in the drawings is as follows:

100. a chromatographic device; 10. a base; 11. a column; 20. a chromatographic tube support; 21. a sleeve; 22. a quadrangle frame; 23. a movable member; 24. a return spring; 25. a toggle rod; 26. positioning columns; 30. a clamping member; 31. a slider; 32. a support arm; 33. a clamping ring.

Detailed Description

Referring to fig. 1, which is a schematic overall structure of the present embodiment, the chromatography apparatus 100 includes a base 10, a column 11 is fixedly installed at the top of the base 10, a chromatography tube support 20 is installed above the column 11, the chromatography tube support 20 includes a sleeve 21 sliding with the column 11, and four corner frames 22 already fixedly installed on the sleeve 21, a movable member 23 is disposed at the rear of the four corner frames 22, and a clamping portion is formed between each corner of the movable member 23 and the four corner frames 22. In this embodiment, the movable member 23 is manually controlled to move away from or close to the four-corner frame 22 to complete the opening and tightening of the clamping portion, and when the movable member 23 is required to be used, that is, the movable member 23 is operated to move away from the four-corner frame 22, the clamping portion is opened at this time, and the chromatographic tube can be placed into the chromatographic tube support 20 to form clamping fixation of the chromatographic tube.

As shown in fig. 3, because not only the fixation of the chromatographic tube but also the convenience of the threaded connection of the chromatographic tube are required, based on this, a set of moving members 23 are respectively provided on the left and right sides of the four-corner frame 22, the moving members 23 are hinged to the back of the four-corner frame 22 through a rotating shaft, and a return spring 24 is provided between two moving members 23 in the same set, and a toggle rod 25 is fixedly mounted at the moving ends of the moving members 23. In this embodiment, the two fingers of one hand respectively control the toggle rod 25 to realize the pressing (even the mutual movement) of the toggle rod 25, at this time, the movable pieces 23 are close to each other and squeeze the return springs 24, the return springs have elastic potential energy, the clamping parts between the movable pieces 23 and the four-corner frames 22 are opened, the chromatographic tube can be placed in the clamping parts, then the toggle rod 25 is released, and under the action of the elastic potential energy of the return springs 24, the opposite force can be applied to the movable pieces 23 to clamp and position the chromatographic tube. The fixing effect is realized. In the prior art, the chromatographic tubes are connected one by arranging the inner threads on the plurality of top ends and the outer protruding thread parts on the bottom ends, so that the lengths of the chromatographic tubes are changed to adapt to different mobile phases. During normal use, the chromatographic tubes at the upper part are firstly fixed through the clamping mechanism, then the chromatographic tubes with the required lengths are butted one by one, and then the lowest chromatographic tube is fixed through the lower clamping assembly. When the chromatographic device is used, the fastening bolt is required to be operated every time the length of the chromatographic tube is changed, so that the chromatographic device is very inconvenient to use; the positioning mechanism in this application only need use one hand to go to operate the toggle rod 25 just can realize opening to accomplish the centre gripping to the chromatographic tube to clamping part, and another hand can make another chromatographic tube dock with last chromatographic tube and rotate and make the two carry out threaded connection fixed.

As shown in fig. 4, further, a positioning column 26 is fixedly mounted at the movable end of the movable member 23, the positioning column 26 is made of rubber material, and the positioning columns 26 are fixedly mounted at the four corners of the four-corner frame 22. In this embodiment, when the chromatographic tube is clamped, the two positioning posts 26 are close to each other and contact with the surface wall of the chromatographic tube, the positioning posts 26 made of rubber have higher contact stability with the chromatographic tube, and because the movable member 23 rotates on the back of the quadrangular frame 22 (i.e. the moving track of the movable end is arc-shaped), the positioning posts 26 are arranged in a cylindrical shape, and can better contact with the surface wall of the chromatographic tube.

As shown in fig. 2 and 5. Further, a plurality of clamping pieces 30 are arranged above the upright 11, the uppermost clamping piece 30 is used for fixing a constant-pressure dropping funnel, the lower clamping piece 30 is used for fixing a pressure interface buffer bottle, the constant-pressure dropping funnel is connected with the pressure interface buffer bottle through a valve, and when the pressure interface buffer bottle is used, the layered device can be connected with an air pressurizing assembly through the pressure interface buffer bottle. The clamping piece 30 comprises a sliding piece 31, two sides of the sliding piece 31 are fixedly provided with supporting arms 32, clamping rings 33 are fixedly arranged on end faces, far away from the sliding piece 31, of the supporting arms 32, the clamping piece 30 can fix a chromatography management assembly, the chromatography management assembly is connected with a chromatography tube through a valve, and a discharge end is further arranged at the bottom of the chromatography tube and used for discharging. Thus forming a complete chromatographic device.

In order to facilitate the use of chromatographic components with different heights, positioning bolts are arranged on the clamping piece 30 and the sleeve 21, the height position of the clamping piece 30 and the sleeve 21 on the upright 11 is fixed by screwing the positioning bolts, and when the positioning bolts are loosened, the height position of the device can be adjusted.

The foregoing description is only a preferred embodiment of the present utility model, but the scope of the present utility model is not limited thereto, and any person skilled in the art, who is within the scope of the present utility model, should make equivalent substitutions or modifications according to the technical solution of the present utility model and the inventive concept thereof, and should be covered by the scope of the present utility model.

Claims

1. The utility model provides a chromatographic separation device, includes base (10) and fixed mounting stand (11) in base (10) top, be provided with chromatographic tube support piece (20) on stand (11), its characterized in that, chromatographic tube support piece (20) include with stand (11) gliding sleeve pipe (21), four corners frame (22) that have fixed mounting on sleeve pipe (21), the rear of four corners frame (22) is provided with moving part (23), moving part (23) with make up into a clamping part between each angle of four corners frame (22).

2. The chromatographic separation device according to claim 1, wherein a group of moving parts (23) are respectively arranged on the left side and the right side of the four-corner frame (22), the moving parts (23) are hinged on the back surface of the four-corner frame (22) through a rotating shaft, a reset spring (24) is arranged between two moving parts (23) in the same group, and a toggle rod (25) is fixedly arranged at the moving end of each moving part (23).

3. The chromatographic separation device according to claim 2, characterized in that the movable end of the movable member (23) is fixedly provided with positioning posts (26), and the four corners of the four-corner frame (22) are also provided with positioning posts (26).

4. A chromatographic separation device in accordance with claim 3 characterized in that the positioning posts (26) are made of rubber material.

5. A chromatographic separation device in accordance with claim 3 characterized in that the positioning posts (26) are arranged in a cylindrical shape.

6. Chromatographic separation device according to claim 1, characterized in that a plurality of clamping members (30) are arranged above the upright (11), the clamping members (30) comprise sliding members (31), supporting arms (32) are fixedly arranged on two sides of the sliding members (31), and clamping rings (33) are fixedly arranged on the end faces, far away from the sliding members (31), of the supporting arms (32).

7. Chromatographic separation device according to claim 6, characterized in that the clamping member (30) and the sleeve (21) are provided with positioning bolts.