CN220495322U - Automatic sterilization room for veterinary drug oral liquid non-high temperature resistant packaging material - Google Patents
Automatic sterilization room for veterinary drug oral liquid non-high temperature resistant packaging material Download PDFInfo
- Publication number
- CN220495322U CN220495322U CN202321785122.7U CN202321785122U CN220495322U CN 220495322 U CN220495322 U CN 220495322U CN 202321785122 U CN202321785122 U CN 202321785122U CN 220495322 U CN220495322 U CN 220495322U
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- CN
- China
- Prior art keywords
- fumigation
- oral liquid
- fumigation chamber
- room
- veterinary drug
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- 230000001954 sterilising effect Effects 0.000 title claims abstract description 37
- 239000007788 liquid Substances 0.000 title claims abstract description 20
- 239000005022 packaging material Substances 0.000 title claims abstract description 20
- 239000000273 veterinary drug Substances 0.000 title claims abstract description 17
- 238000004659 sterilization and disinfection Methods 0.000 title claims description 22
- 238000003958 fumigation Methods 0.000 claims abstract description 63
- 238000007789 sealing Methods 0.000 claims description 27
- 238000010438 heat treatment Methods 0.000 claims description 22
- 238000011049 filling Methods 0.000 claims description 12
- 238000007599 discharging Methods 0.000 claims description 10
- 238000012544 monitoring process Methods 0.000 claims description 3
- 230000002457 bidirectional effect Effects 0.000 claims description 2
- 239000000645 desinfectant Substances 0.000 abstract description 14
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 239000003595 mist Substances 0.000 abstract description 4
- 239000000126 substance Substances 0.000 abstract description 3
- 238000000746 purification Methods 0.000 abstract description 2
- 239000000463 material Substances 0.000 description 17
- 239000007789 gas Substances 0.000 description 6
- 238000003860 storage Methods 0.000 description 6
- 230000005540 biological transmission Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 230000007613 environmental effect Effects 0.000 description 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 2
- LOUPRKONTZGTKE-WZBLMQSHSA-N Quinine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@@H]2[C@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-WZBLMQSHSA-N 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- CPKVUHPKYQGHMW-UHFFFAOYSA-N 1-ethenylpyrrolidin-2-one;molecular iodine Chemical compound II.C=CN1CCCC1=O CPKVUHPKYQGHMW-UHFFFAOYSA-N 0.000 description 1
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 description 1
- 235000001258 Cinchona calisaya Nutrition 0.000 description 1
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 1
- 229920000153 Povidone-iodine Polymers 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 238000000889 atomisation Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229960002233 benzalkonium bromide Drugs 0.000 description 1
- KHSLHYAUZSPBIU-UHFFFAOYSA-M benzododecinium bromide Chemical compound [Br-].CCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 KHSLHYAUZSPBIU-UHFFFAOYSA-M 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- LOUPRKONTZGTKE-UHFFFAOYSA-N cinchonine Natural products C1C(C(C2)C=C)CCN2C1C(O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-UHFFFAOYSA-N 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- -1 compound potassium hydrogen persulfate Chemical class 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005429 filling process Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229960001621 povidone-iodine Drugs 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 229960000948 quinine Drugs 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000012859 sterile filling Methods 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 230000026683 transduction Effects 0.000 description 1
- 238000010361 transduction Methods 0.000 description 1
Landscapes
- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
The utility model belongs to the technical field of aseptic purification production, and particularly relates to an automatic sterilizing room for non-high-temperature-resistant packaging materials of veterinary drug oral liquid. The air exhaust fan is utilized to replace the gas in the fumigation chamber through the air inlet pipeline and the air exhaust pipeline, so that the sterilized disinfectant mist is rapidly discharged from the fumigation chamber, and the sterilizing filter on the air inlet pipeline and the one-way air outlet valve on the air exhaust pipeline ensure that sterile substances enter when the fumigation chamber exchanges gas with the outside.
Description
Technical Field
The utility model belongs to the technical field of sterile purification production, and particularly relates to an automatic sterilization room for non-high-temperature-resistant packaging materials of veterinary drug oral liquid.
Background
The products produced in the D-level clean area generally comprise solid oral preparations, such as tablets, granules, capsules and the like, and can also be high-concentration oral liquid, and when the filling process of the oral liquid is carried out in the D-level clean area, various materials entering a clean workshop are subjected to unpacking, cleaning and other treatments in an unpacking room, wherein the unpacking room is generally arranged across the clean area and the non-clean area, the unpacking room generally comprises two rooms, one unpacking room in the non-clean area, one material temporary storage room in the clean area, and the two rooms form a generalized unpacking room, namely the unpacking room is arranged across the clean area. In order to ensure that microorganisms of products produced in the D-level clean area cannot exceed standards, a transmission window is generally adopted when material transfer is carried out between a packaging material temporary storage room and an unpacking room of a D-level workshop for producing the traditional veterinary drug oral liquid.
But the delivery window volume is less, can't transfer the great material of volume to transfer material inefficiency. In addition, materials entering the transmission window need to be guaranteed to be in a sterile state, namely, the materials in the earlier stage need to be sterilized, and the non-sterile materials cannot be transmitted.
Disclosure of Invention
The utility model aims to solve the problems and provide an automatic sterilizing room for non-high-temperature-resistant packaging materials of veterinary drug oral liquid. The air exhaust fan is utilized to replace the gas in the fumigation chamber through the air inlet pipeline and the air exhaust pipeline, so that the sterilized disinfectant mist is rapidly discharged from the fumigation chamber, and the sterilizing filter on the air inlet pipeline and the one-way air outlet valve on the air exhaust pipeline ensure that sterile substances enter when the fumigation chamber exchanges gas with the outside.
The technical problems to be solved by the utility model are realized by adopting the following technical scheme: an automatic sterilizing room for veterinary drug oral liquid non-high temperature resistant packaging materials comprises a fumigation room connected with a clean area of a filling room, an atomizer arranged in the fumigation room, a circulating fan and a temperature control module;
an air inlet pipeline and an air exhaust pipeline are arranged on the fumigation chamber, a sterilizing filter is arranged on the air inlet pipeline, and an air exhaust fan and a one-way air outlet valve are arranged on the air exhaust pipeline;
a feeding sealing door is arranged at the left side of the fumigation chamber, and a discharging sealing door communicated with a clean area of the filling chamber is arranged at the right side of the fumigation chamber;
the temperature control module is used for controlling the temperature between fumigation chambers.
The technical scheme of the utility model is as follows: the temperature control module comprises an environment heating device and a temperature sensor;
the temperature sensor is used for monitoring the temperature between fumigation chambers;
the environment heating device is used for heating the environment in the fumigation chamber. The temperature sensor monitors the temperature between the fumigating rooms, the threshold temperature in the fumigating rooms is set, when the environmental temperature in the fumigating rooms is lower than the threshold temperature, the environmental heating device is used for heating the environment in the fumigating rooms, the environmental temperature in the fumigating rooms is higher than the threshold temperature, and therefore the temperature requirement of volatilization of disinfectant is met, and the sterilization effect is guaranteed.
The technical scheme of the utility model is as follows: the environment heating device is arranged at an air inlet of the circulating fan. The environment heating device is arranged at the air inlet of the circulating fan, so that heated gas can circularly flow in the fumigation chamber, and the environment temperature in the fumigation chamber is rapidly improved.
The technical scheme of the utility model is as follows: and the feeding sealing door and the discharging sealing door are respectively provided with a bidirectional electronic lock. Through set up two-way electronic lock on feeding sealing door and ejection of compact sealing door, can guarantee that the user can open and close feeding sealing door and ejection of compact sealing door from inside and outside the fumigation room.
The technical scheme of the utility model is as follows: the air inlet pipeline is provided with an air inlet valve. Through setting up electric valve on the air inlet pipeline, during fumigating, through closing electric valve, can avoid the antiseptic solution fog in the fumigation room to follow air inlet pipeline and discharge, improve sealed sterilization efficiency.
The technical scheme of the utility model is as follows: the atomizer comprises an ultrasonic atomizer.
Compared with the prior art, the utility model has the beneficial effects that: according to the utility model, the existing transmission window structure is replaced by the fumigation room connected with the clean area of the filling room, so that non-sterile materials can be sterilized, the efficiency of entering the filling room by the materials such as the packaging material container is improved, and bacterial pollution caused by carrying the packaging material container is greatly reduced.
The temperature control module is used for controlling the temperature between fumigation chambers to meet the volatilizing temperature requirement of the disinfectant, the atomizer is used for atomizing the disinfectant to sterilize materials in the fumigation chambers, and the circulating fan is used for enabling disinfectant mist to circulate in the fumigation chambers, so that sterilization dead angles are avoided, and sterilization efficiency is improved. The fumigation temperature of the disinfectant is lower and is generally over 20 ℃, so that the disinfectant can sterilize non-high-temperature-resistant packaging materials, and is suitable for sterilizing more similar materials.
After sterilization is completed, the disinfectant mist is discharged through the exhaust pipeline by utilizing the exhaust fan, the one-way air outlet valve can prevent external air from entering the fumigation chamber from the exhaust pipeline, and fresh air enters the fumigation chamber after being sterilized and filtered by the sterilizing filter, so that the environment in the fumigation chamber is kept in a sterile state. The material to be sterilized can be sent into the fumigation chamber from one side of the feeding sealing door, and the sterilized material can be moved to one side of the clean area of the filling workshop from one side of the discharging sealing door.
Drawings
Fig. 1 is a schematic structural diagram of an automatic sterilization room of a veterinary drug oral liquid non-high temperature resistant packaging material;
in the figure, a fumigation chamber 1, an atomizer 2, a circulating fan 3 and a sterilization filter 4 are arranged;
101 air inlet pipelines and 102 air exhaust pipelines;
the device comprises an exhaust fan 5, a one-way air outlet valve 6, a feeding sealing door 7, a discharging sealing door 8, an environment heating device 9, a two-way electronic lock 10 and an electric valve 11.
Detailed Description
The technical solutions in the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model.
As shown in figure 1, an automatic sterilizing room for veterinary drug oral liquid non-high temperature resistant packaging materials comprises a fumigation room 1 connected with a clean area of a filling room, an atomizer 2 arranged in the fumigation room 1, a circulating fan 3 and a temperature control module. Wherein the atomizer 2 comprises an ultrasonic atomizer. The circulating fan 3 is arranged at the left upper part of the fumigation chamber 1, and the outlet of the circulating fan 3 is horizontally arranged rightward, so that the gas in the upper space and the lower space of the fumigation chamber 1 can be fully mixed, and atomized disinfectant is prevented from being gathered below the fumigation chamber 1.
An air inlet pipeline 101 and an air exhaust pipeline 102 are arranged on the fumigation chamber 1, a sterilizing filter 4 is arranged on the air inlet pipeline 101, and an air exhaust fan 5 and a one-way air outlet valve 6 are arranged on the air exhaust pipeline 102.
The left side of the fumigation chamber 1 is provided with a feeding sealing door 7, and the right side of the fumigation chamber 1 is provided with a discharging sealing door 8 communicated with a clean area of the filling chamber.
The temperature control module is used for controlling the temperature of the fumigation chamber 1.
The temperature control module comprises an ambient heating device 9, a temperature sensor and a controller.
The temperature sensor is used for monitoring the temperature of the fumigation chamber 1.
The environment heating device 9 is used for heating the environment in the fumigation chamber 1.
The controller is used for controlling the starting and the closing of the environment heating device 9 according to the comparison between the temperature of the fumigation chamber 1 and the preset temperature, which are measured by the temperature sensor, so as to ensure that the environment temperature in the fumigation chamber 1 is maintained at the preset temperature.
The environment heating device 9 is arranged at the air inlet of the circulating fan 3. Specifically, the environmental heating device 9 is an explosion-proof heating fan, and the circulating fan 3 is an air disturbance fan.
And a two-way electronic lock 10 is respectively arranged on the feeding sealing door 7 and the discharging sealing door 8.
The automatic sterilizing room of the veterinary drug oral liquid non-high temperature resistant packaging material also comprises an electric valve 11 arranged on the air inlet pipeline 101.
Working principle:
a. when sterilizing non-sterile plastic or glass bottles or metal bottles or other packaging materials to be sterilized, firstly, one side of a feed sealing door 7 enters the fumigation chamber 1, sterilized materials are orderly discharged in the fumigation chamber 1 according to production requirements, and then the feed sealing door 7 is closed.
b. After the feed sealing door 7 is closed, a temperature sensor in the temperature control module starts to detect the ambient temperature. When the temperature of the fumigation chamber 1 is lower than the set volatilization temperature, the environment heating device 9 and the circulating fan 3 start to work, when the temperature reaches the set volatilization temperature, the environment heating device 9 stops working, meanwhile, the atomizer 2 starts to work, different atomization times are set according to different disinfectants and the volume of the fumigation chamber 1, and when the preset time is reached, the atomizer 2 stops working. The fumigation chamber 1 is in a static fumigation disinfection state, and the circulating fan 3 is always in a working state during the period.
c. When the time reaches the set exhaust time, the exhaust fan 5 and the electric valve 11 are opened, fresh air enters the fumigation chamber 1 through the sterilizing filter 4, the gas with the disinfectant is exhausted out of the fumigation chamber 1 through the one-way air outlet valve 6, after the set exhaust odor removal requirement is met, the two-way electronic lock 10 of the discharging sealing door 8 on one side of the filling chamber of the clean area is unlocked, the green light is turned on, and the sterilizing process is finished.
The application has the advantages that:
1. the utility model changes the transmission window between the temporary storage room and the unpacking room of the D-level workshop packing materials for producing veterinary drug oral liquid into the automatic sterilization room of double leaves, and the temporary storage room replaces the function of the transmission window, thereby expanding the storage space.
2. The efficiency of packing material container entering workshop has been improved, the bacterial contamination that the very big reduction container carried and caused. The method is matched with a full sterile filling process, omits a process link of final sterilization, reduces or avoids the addition of preservative, obviously reduces the production cost and improves the stability and the storage time of the drug solution.
3. The automatic sterilization room of the application contains a two-way electronic lock 10, when a feeding sealing door 7 communicated with the unpacking room is opened, a discharging sealing door 8 of the filling room facing the D-level environment is automatically closed, and vice versa, so that the filling room is prevented from being communicated with the outside.
4. The atomized transduction piece of the ultrasonic atomizer is subjected to ceramic glaze sealing treatment, and can atomize formalin solution with the concentration of less than 30%, glutaraldehyde solution with the concentration of less than 10%, benzalkonium bromide solution with the concentration of less than 15%, compound potassium hydrogen persulfate solution with the concentration of less than 5%, povidone iodine solution with the concentration of less than 5% and quinine bromide solution with the concentration of less than 4% under the environment of the room temperature of not less than 20 ℃ at the frequency of 1700 Hz.
5. The environment heating device 9 can keep the sterilizing and fumigating environment above 20 ℃, thereby meeting the requirement of the volatilization temperature of the disinfectant and avoiding the disinfectant from becoming liquid and not playing a role in disinfection.
6. The disinfection fog circularly flows in the fumigation chamber 1 by utilizing the explosion-proof pipeline type exhaust fan and the explosion-proof air disturbance fan, so that no dead angle is ensured in the fumigation space in the fumigation process, and the harmful gas is ensured to be discharged cleanly from the fumigation chamber 1 in time after fumigation.
7. The sterilizing filter 4 with fresh air filtering and sterilizing functions, the electric valve 11 and the one-way air outlet valve 6 ensure that sterile substances enter when the fumigation chamber 1 exchanges air.
Claims (6)
1. An automatic sterilization room for veterinary drug oral liquid non-high temperature resistant packaging materials, which is characterized in that: comprises a fumigation room (1) connected with a clean area of a filling room, an atomizer (2) arranged in the fumigation room (1), a circulating fan (3) and a temperature control module;
an air inlet pipeline (101) and an air exhaust pipeline (102) are arranged on the fumigation chamber (1), a sterilizing filter (4) is arranged on the air inlet pipeline (101), and an air exhaust fan (5) and a one-way air outlet valve (6) are arranged on the air exhaust pipeline (102);
a feeding sealing door (7) is arranged at the left side of the fumigation chamber (1), and a discharging sealing door (8) communicated with a clean area of the filling chamber is arranged at the right side of the fumigation chamber (1);
the temperature control module is used for controlling the temperature of the fumigation chamber (1).
2. The automatic sterilization booth for veterinary drug oral liquid non-high temperature resistant packaging materials according to claim 1, wherein: the temperature control module comprises an environment heating device (9) and a temperature sensor;
the temperature sensor is used for monitoring the temperature of the fumigation chamber (1);
the environment heating device (9) is used for heating the environment in the fumigation chamber (1).
3. The automatic sterilization booth for veterinary drug oral liquid non-high temperature resistant packaging materials according to claim 2, wherein: the environment heating device (9) is arranged at the air inlet of the circulating fan (3).
4. The automatic sterilization booth for veterinary drug oral liquid non-high temperature resistant packaging materials according to claim 1, wherein: and the feeding sealing door (7) and the discharging sealing door (8) are respectively provided with a bidirectional electronic lock (10).
5. The automatic sterilization booth for veterinary drug oral liquid non-high temperature resistant packaging materials according to claim 1, wherein: the air inlet pipeline (101) is provided with an electric valve (11).
6. The automatic sterilization booth for veterinary drug oral liquid non-high temperature resistant packaging materials according to claim 1, wherein: the atomizer (2) comprises an ultrasonic atomizer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321785122.7U CN220495322U (en) | 2023-07-07 | 2023-07-07 | Automatic sterilization room for veterinary drug oral liquid non-high temperature resistant packaging material |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321785122.7U CN220495322U (en) | 2023-07-07 | 2023-07-07 | Automatic sterilization room for veterinary drug oral liquid non-high temperature resistant packaging material |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220495322U true CN220495322U (en) | 2024-02-20 |
Family
ID=89866391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321785122.7U Active CN220495322U (en) | 2023-07-07 | 2023-07-07 | Automatic sterilization room for veterinary drug oral liquid non-high temperature resistant packaging material |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220495322U (en) |
-
2023
- 2023-07-07 CN CN202321785122.7U patent/CN220495322U/en active Active
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