CN220485677U - Active ingredient enrichment device - Google Patents
Active ingredient enrichment device Download PDFInfo
- Publication number
- CN220485677U CN220485677U CN202321984490.4U CN202321984490U CN220485677U CN 220485677 U CN220485677 U CN 220485677U CN 202321984490 U CN202321984490 U CN 202321984490U CN 220485677 U CN220485677 U CN 220485677U
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- China
- Prior art keywords
- active ingredient
- collecting part
- cavity
- enrichment
- inner cylinder
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- 239000004480 active ingredient Substances 0.000 title claims abstract description 104
- 238000000034 method Methods 0.000 claims abstract description 7
- 239000008280 blood Substances 0.000 claims description 55
- 210000004369 blood Anatomy 0.000 claims description 55
- 210000001185 bone marrow Anatomy 0.000 claims description 33
- 239000000463 material Substances 0.000 claims description 19
- 238000007789 sealing Methods 0.000 claims description 11
- 239000007788 liquid Substances 0.000 abstract description 7
- 230000004087 circulation Effects 0.000 abstract description 6
- 239000002699 waste material Substances 0.000 abstract description 3
- 210000000988 bone and bone Anatomy 0.000 description 8
- 210000000130 stem cell Anatomy 0.000 description 5
- 230000000740 bleeding effect Effects 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
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- External Artificial Organs (AREA)
Abstract
The utility model provides an active ingredient enrichment device, which comprises an inner cylinder and an outer cylinder which are coaxially arranged, wherein an active ingredient collecting part is radially clamped and embedded on the inner cylinder, the active ingredient collecting part can be taken out, and an active ingredient collecting part must be passed through in the process of reciprocating flow of enrichment liquid in a first chamber and a second chamber; the second piston assembly is pushed forward, so that the liquid to be enriched enters the first chamber after passing through the active ingredient collecting part, and the first piston assembly is pushed forward, so that the liquid to be enriched flows back into the second chamber after passing through the active ingredient collecting part. The active ingredient collecting part is radially embedded on the inner cylinder, the active ingredient collecting part is used as a part of the inner cylinder and is matched with the outer cylinder which is coaxially arranged, the reciprocating circulation of the enrichment liquid can be successfully completed only by a short stroke, the waste amount of the enrichment liquid is very small, and the operation of enriching the active ingredient is simple, convenient and handy.
Description
Technical Field
The present utility model relates to an active ingredient enrichment device.
Background
The document CN113493739a provides a stem cell enrichment device, in which the upper cover and the lower cover of a bone storage tube are in threaded connection, and a bone marrow reflux tube is connected with a filter bowl through a circulation pipeline, when the stem cell enrichment device is used, firstly, air tightness is checked, if the air tightness is good, a valve of a blood injection port is opened to inject a proper volume of blood, after the blood is injected, the valve of the blood injection port is closed, an operator presses a piston rod of a first blood storage tube to enable a piston of a first blood storage tube to move downwards, and simultaneously, the piston of a second blood storage tube moves upwards under the lifting action of a rope, blood in the first blood storage tube flows out through a first bleeding port under the pressure of the piston of the first blood storage tube and the suction action of the piston of the second blood storage tube, and after the stem cells in the blood flow into the first bone storage tube are enriched on a porous material in the first bone storage tube, the stem cells flow into the first pipeline through an outlet, and then flow into the second blood inlet along the first pipeline; the operating personnel presses the piston rod of the second blood storage tube to enable the piston of the second blood storage tube to move downwards, meanwhile, the piston of the first blood storage tube moves upwards, blood in the second blood storage tube flows into the second bone storage tube through the second bleeding port and the inlet of the second bone storage tube under the action of pressure and suction, stem cells in the blood are enriched on porous materials in the blood, then flows into the second pipeline through the outlet of the second bone storage tube, and enters the first blood storage tube along the second pipeline to complete one cycle.
The scheme is only suitable for the situation that the using amount of the bone marrow blood is large (more than 20 mL), and in some special situations (such as dental bone grafting, bone grafting of a spine interbody fusion device and the like), the required filling material is very small (0.5 mL of filling material), and correspondingly, the bone marrow blood is relatively small (2-2.5 mL of bone marrow blood). However, there is currently a lack of an enrichment apparatus suitable for rapid enrichment of trace volumes (2-10 mL) of bone marrow blood active ingredients.
Disclosure of Invention
The utility model aims to provide an active ingredient enrichment device which at least can solve the technical problem of how to rapidly enrich active ingredients aiming at extracted trace bone marrow blood.
The utility model adopts the following technical scheme.
The utility model provides an active ingredient enrichment ware, including the inner tube and the urceolus of coaxial setting, part of inner tube is located the urceolus, be provided with first passageway in inner tube front portion, be provided with the second passageway in urceolus front portion, the first cavity of inner tube communicates with each other with the second cavity of urceolus, be provided with first piston assembly in the first cavity, be provided with the second piston assembly in the second cavity, the second piston assembly is connected with the inner tube front portion, be provided with active ingredient collection portion between first cavity and second cavity, active ingredient collection portion radially clamps on the inner tube, active ingredient collection portion can be taken out, and the marrow blood must pass through active ingredient collection portion in the in-process of reciprocating flow in first cavity and second cavity.
Further, the active ingredient collecting part comprises a cylinder body and at least two filter screens arranged on the cylinder body, at least two filter screens and the inner wall of the cylinder body jointly form a space for storing the enrichment filling material, and the volume of the space corresponds to the volume of the enrichment filling material.
Preferably, the active ingredient collecting part comprises a cylinder body and two filter screens arranged at two ends of the cylinder body, and a space for storing the enriched filling material is jointly formed by the two filter screens and the inner wall of the cylinder body. More preferably, the filter screen is stuck to both ends of the cylinder, or the filter screen is fastened (fixed) to both ends of the cylinder.
Further, sealing elements are arranged at two ends of the cylinder body, and the connecting parts of the active ingredient collecting part and the inner cylinder are sealed by adopting the sealing elements.
In order to be more convenient and smooth to take and mount the active ingredient collecting part, the inner cylinder is provided with a notch, and when the active ingredient collecting part is clamped in the notch, part of the side wall of the active ingredient collecting part is abutted against the inner wall of the inner cylinder. When in use, the active ingredient collecting part is inserted into the notch; after enrichment is completed, the active ingredient collecting part is taken out from the notch, and then the enrichment filling material in the active ingredient collecting part is taken out for use.
In order to further reduce the amount of bone marrow blood, one end of the active ingredient collecting part is abutted against the bottom wall of the first chamber.
In the utility model, the front end of the second channel is provided with a detachable cover body; the inner barrel may be employed directly as a second piston assembly in the second chamber.
In the utility model, an annular piece fixedly arranged at the front part of the inner cylinder can be used as a second piston assembly in the second cavity, the outer wall of the inner cylinder is provided with a sleeve, the front end of the sleeve is fixedly connected with the annular piece, and the active ingredient collecting part is radially limited by the sleeve.
When in use, the method comprises the following steps:
step 1, pulling back a second piston assembly in a second chamber to pump bone marrow blood into the second chamber;
step 2, sealing the second channel;
step 3, pushing the second piston assembly in the second chamber forwards to enable the bone marrow blood to enter the first chamber after passing through the active ingredient collecting part, and moving the first piston assembly backwards in the process;
step 4, pushing the first piston assembly forwards to enable the bone marrow blood to flow back into the second chamber after passing through the active ingredient collecting part;
and 5, repeating the step 3 and the step 4 for a plurality of times, and taking out the enriched filling material with the active ingredients after enrichment.
The beneficial effects are that: according to the utility model, the active ingredient collecting part is radially embedded on the inner cylinder in an ingenious manner, the active ingredient collecting part is used as a part of the inner cylinder, the coaxial outer cylinder is matched, the reciprocating circulation of the bone marrow blood can be smoothly completed with a short stroke, the waste amount of the bone marrow blood is very small, and the active ingredient can be enriched rapidly for about 2-2.5ml even smaller bone marrow blood by adopting the structure, so that the bone marrow blood with different volumes can be matched by changing the active ingredient collecting part with different volumes when in use.
By adopting the scheme of the utility model, the operation of enriching the active ingredients is simple, convenient and handy, and the reciprocating circulation of the marrow blood in the first chamber and the second chamber can be realized by pushing the piston components in the inner cylinder and the outer cylinder forwards during the operation; the active ingredient enrichment device has the advantages of small structure, portability and low manufacturing cost.
Drawings
FIG. 1 is a schematic diagram showing the external structure of an active ingredient enrichment device in example 1;
FIG. 2 is a cross-sectional view of FIG. 1;
FIG. 3 is a schematic diagram showing the external structure of an active ingredient enrichment device in example 1;
FIG. 4 is a cross-sectional view of FIG. 3;
FIG. 5 is a schematic view of the inner cylinder structure of the active ingredient enrichment device of example 1 (equipped with an active ingredient collecting part);
FIG. 6 is a schematic view of the inner cylinder structure of the active ingredient enrichment device of example 1 (no active ingredient collecting part is installed);
FIG. 7 is a schematic view of an active ingredient collection portion of the active ingredient enrichment device of example 1;
fig. 8 is a schematic view of an active ingredient collection portion of the active ingredient enrichment device of example 3.
Description of the embodiments
The following description of the embodiments of the present utility model will be apparent and complete, and it is to be understood that the embodiments described are merely some, but not all embodiments of the present utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Examples
Referring to fig. 1 to 7, an active ingredient enrichment apparatus includes an inner cylinder 1 and an outer cylinder 2 coaxially disposed, a part of the inner cylinder 1 is located in the outer cylinder 2, a first passage 11 is provided at the front of the inner cylinder 1, a second passage 21 is provided at the front of the outer cylinder 2, a first chamber 12 of the inner cylinder 1 communicates with a second chamber 22 of the outer cylinder 2, a first piston assembly 13 is provided in the first chamber 12, a second piston assembly 23 is provided in the second chamber 22, the second piston assembly 23 is connected with the front of the inner cylinder 1, an active ingredient collecting portion 3 is provided between the first chamber 12 and the second chamber 12, the active ingredient collecting portion 3 is radially caught on the inner cylinder 1, the active ingredient collecting portion 3 can be taken out, and bone marrow blood must pass through the active ingredient collecting portion 3 during the reciprocating flow in the first chamber 12 and the second chamber 22.
In this embodiment, as shown in fig. 7, the active ingredient collection portion 3 includes a cylindrical body 31 and two screens 32 provided at both ends of the cylindrical body 31, and a space for storing the enriched filler 33 is formed by the two screens 32 and the inner wall of the cylindrical body 31. Sealing elements are provided at both ends of the cylindrical body 31, and the connection portion between the active ingredient collecting portion 3 and the inner cylinder 1 is sealed by the sealing elements. As shown in fig. 6, the inner tube 1 is provided with a notch 14, and when the active ingredient collecting portion 3 is fitted into the notch 14, a part of the side wall of the active ingredient collecting portion 3 is abutted against the inner wall of the inner tube 1, and the removable active ingredient collecting portion 3 is substantially a part of the inner tube 1. Wherein one end of the active ingredient collection portion 3 abuts against the bottom wall of the first chamber 12.
In this embodiment, the front end of the second channel 21 is provided with a detachable cover 24; the annular piece 15 fixedly arranged at the front part of the inner cylinder 1 is used as a second piston assembly in the second chamber 22, the outer wall of the inner cylinder 1 is provided with the sleeve 4, the annular piece 15 is fixedly connected with the front end of the sleeve 4, and the active ingredient collecting part 3 is radially limited by means of the sleeve 4.
When in use, a proper active ingredient collecting part 3 is selected in advance according to the required amount of the bone marrow blood, if the required volume of the bone marrow blood is 0.5ml, the active ingredient collecting part 3 which can just store 0.1ml of the enrichment filling material 33 can be selected, and then the active ingredient collecting part 3 is inserted into the notch 14; then, a liquid taking needle connected to the first passage 11 is inserted into a site where bone marrow blood (bone marrow) can be sucked, and then the following steps are performed;
step 1, pulling the second piston assembly in the second chamber 22 backwards to draw the bone marrow blood into the second chamber 22;
step 2, taking out the liquid taking needle, and sealing the second channel 21 by using the cover body 24, wherein the state is shown in fig. 1 and 2;
step 3, pushing the second piston assembly in the second chamber 22 forward, so that the bone marrow blood passes through the active ingredient collecting part 3 and enters the first chamber 12, and the state is shown in fig. 3 and 4, and in the process, the first piston assembly 13 moves backward;
step 4, pushing the first piston assembly 13 forward to make the bone marrow blood flow back to the second chamber 22 after passing through the active ingredient collecting part 3, and the state at this time is shown in fig. 1 and 2 again;
and 5, repeating the step 3 and the step 4 for a plurality of times, and taking out the enriched filling material 33 with the active ingredients after enrichment.
In the active ingredient enrichment process, when the second piston assembly moves forward, the bone marrow blood in the second chamber 22 firstly passes through the first channel 11 and the active ingredient collecting part 3 and then enters the first chamber 12, and a first part of active ingredients in the bone marrow blood (bone marrow) can be remained in the enrichment filling material 33; when the first piston assembly 13 moves forward, the marrow blood in the first chamber 12 flows back to the second chamber 22 after passing through the active ingredient collecting part 3 and the first channel 11, and a second part of active ingredients in the marrow blood also remain in the enrichment filling material 33, so that the marrow blood completes one cycle; advancing the piston assembly in the manner described above allows the bone marrow blood to complete multiple cycles, each of which is enriched with a portion of the active ingredient remaining in the enriched fill material 33.
In this embodiment, the length (the dimension in the axial direction) of the active ingredient collecting portion 3 can be 3mm (the thickness of the single filter screen 32 is about 0.5mm, the length of the cylinder 31 is 2mm, the cylinder 31 with the length not exceeding 5mm can be directly replaced by a sealing ring), the active ingredient collecting portion is radially clamped on the inner cylinder, the active ingredient collecting portion is used as a part of the inner cylinder, and the active ingredient collecting portion 3 can meet the active ingredient enrichment requirement only by processing the active ingredient collecting portion 3 into a very short segment.
Examples
An active ingredient enrichment device, the main structure of which is referred to in example 1, differs from that of example 1 in that: the annular part 15 and the sleeve 4 are omitted, the inner cylinder 1 is directly adopted as a second piston assembly in the second chamber 22, and a sealing ring is arranged on the outer wall of the inner cylinder 1.
Examples
An active ingredient enrichment device, the main structure of which is referred to in example 1, differs from that of example 1 in that: as shown in fig. 8, the active ingredient collecting part 3 includes a cylindrical body 31 and five screens 32 provided on the cylindrical body 31, a space for storing the enriched filling material 33 is formed by the five screens 32 and the inner wall of the cylindrical body 31, and a space for storing the enriched filling material 33 is formed by two adjacent screens 32 and the inner wall of the cylindrical body 31, and only the enriched filling material 33 adapted according to the desired bone marrow blood is required to be contained in a plurality of space units when in use (only one space unit is required when the volume of the enriched filling material 33 does not exceed the volume of the space unit, and only two space units are required when the volume of the enriched filling material 33 exceeds the volume of the space unit but does not exceed the volume of the two space units).
In various embodiments, when the length of the notch 14 is not changed and enrichment is required for different volumes of bone marrow blood, sealing elements with different heights can be selected to match with active ingredient collecting parts 3 with different lengths.
According to the utility model, the active ingredient collecting part is radially embedded on the inner cylinder in a ingenious manner, the active ingredient collecting part is used as a part of the inner cylinder, the coaxial outer cylinder is matched, the reciprocating circulation of the bone marrow blood can be smoothly completed with a short stroke, the waste amount of the bone marrow blood is very small, and the active ingredient can be enriched rapidly for about 2-2.5ml even smaller bone marrow blood by adopting the structure, so that the bone marrow blood with different volumes can be matched by changing the active ingredient collecting part with different volumes when in use; by adopting the scheme of the utility model, the operation of enriching the active ingredients is simple, convenient and handy, and the reciprocating circulation of the marrow blood in the first chamber and the second chamber can be realized by pushing the piston components in the inner cylinder and the outer cylinder forwards during the operation; the active ingredient enrichment device has the advantages of small structure, portability and low manufacturing cost.
Claims (8)
1. The utility model provides an active ingredient enrichment ware, includes inner tube (1) and urceolus (2) of coaxial setting, and one of them part of inner tube (1) is located urceolus (2), is provided with first passageway (11) in inner tube (1) front portion, is provided with second passageway (21) in urceolus (2) front portion, and first cavity (12) of inner tube (1) communicate with each other with second cavity (22) of urceolus (2), its characterized in that: be provided with first piston assembly (13) in first cavity (12), be provided with second piston assembly (23) in second cavity (22), second piston assembly (23) are connected with inner tube (1) front portion, be provided with active ingredient collection portion (3) between first cavity (12) and second cavity (22), active ingredient collection portion (3) radial inlay card is on inner tube (1), active ingredient collection portion (3) can be taken out, and the in-process that bone marrow blood reciprocated in first cavity (12) and second cavity (22) must pass through active ingredient collection portion (3).
2. The active ingredient-enriching machine according to claim 1, characterized in that: the active ingredient collecting part (3) comprises a cylinder body (31) and at least two filter screens (32) arranged on the cylinder body (31), and at least two filter screens (32) and the inner wall of the cylinder body (31) jointly form a space for storing an enrichment filling material (33).
3. The active ingredient enrichment device according to claim 2, wherein: the active ingredient collecting part (3) comprises a cylinder body (31) and two filter screens (32) arranged at two ends of the cylinder body (31), and a space for storing an enrichment filling material (33) is jointly formed by the two filter screens (32) and the inner wall of the cylinder body (31).
4. An active ingredient enrichment device according to claim 3, wherein: sealing elements are arranged at two ends of the cylinder body (31), and the connecting part of the active ingredient collecting part (3) and the inner cylinder (1) is sealed by adopting the sealing elements.
5. The active ingredient-enriching machine according to claim 4, characterized in that: the inner cylinder (1) is provided with a notch (14), and when the active ingredient collecting part (3) is clamped in the notch (14), part of the side wall of the active ingredient collecting part (3) is attached to the inner wall of the inner cylinder (1).
6. The active ingredient-enriching machine according to any one of claims 1-5, characterized in that: one end of the active ingredient collecting part (3) is abutted against the bottom wall of the first cavity (12).
7. The active ingredient-enriching machine according to claim 6, characterized in that: the front end of the second channel (21) is provided with a detachable cover body (24); the inner cylinder (1) is adopted as a second piston assembly in the second chamber (22) directly.
8. The active ingredient-enriching machine according to claim 6, characterized in that: the annular piece (15) fixedly arranged at the front part of the inner cylinder (1) is used as a second piston assembly in the second cavity (22), the sleeve (4) is arranged on the outer wall of the inner cylinder (1), the annular piece (15) is fixedly connected with the front end of the sleeve (4), and the active ingredient collecting part (3) is radially limited by means of the sleeve (4).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321984490.4U CN220485677U (en) | 2023-07-26 | 2023-07-26 | Active ingredient enrichment device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321984490.4U CN220485677U (en) | 2023-07-26 | 2023-07-26 | Active ingredient enrichment device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220485677U true CN220485677U (en) | 2024-02-13 |
Family
ID=89838870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321984490.4U Active CN220485677U (en) | 2023-07-26 | 2023-07-26 | Active ingredient enrichment device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220485677U (en) |
-
2023
- 2023-07-26 CN CN202321984490.4U patent/CN220485677U/en active Active
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| GR01 | Patent grant | ||
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