CN220459374U - Visual cell sampler of endometrium - Google Patents
Visual cell sampler of endometrium Download PDFInfo
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- CN220459374U CN220459374U CN202320497587.6U CN202320497587U CN220459374U CN 220459374 U CN220459374 U CN 220459374U CN 202320497587 U CN202320497587 U CN 202320497587U CN 220459374 U CN220459374 U CN 220459374U
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- probe
- sampling brush
- endometrium
- endoscope
- sampling
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- 210000004696 endometrium Anatomy 0.000 title claims abstract description 32
- 230000000007 visual effect Effects 0.000 title abstract description 11
- 238000005070 sampling Methods 0.000 claims abstract description 66
- 239000000523 sample Substances 0.000 claims abstract description 58
- 210000004027 cell Anatomy 0.000 claims abstract description 50
- 239000012528 membrane Substances 0.000 claims abstract description 9
- 210000005168 endometrial cell Anatomy 0.000 claims abstract description 6
- 238000000926 separation method Methods 0.000 claims abstract description 4
- 230000002357 endometrial effect Effects 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 3
- 239000002184 metal Substances 0.000 claims description 3
- 239000004033 plastic Substances 0.000 claims description 3
- 239000000741 silica gel Substances 0.000 claims description 3
- 229910002027 silica gel Inorganic materials 0.000 claims description 3
- 230000004888 barrier function Effects 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 9
- 206010014759 Endometrial neoplasm Diseases 0.000 abstract description 8
- 206010014733 Endometrial cancer Diseases 0.000 abstract description 7
- 238000012216 screening Methods 0.000 abstract description 7
- 238000003745 diagnosis Methods 0.000 abstract description 3
- 230000036285 pathological change Effects 0.000 abstract description 2
- 231100000915 pathological change Toxicity 0.000 abstract description 2
- 230000003902 lesion Effects 0.000 description 13
- 230000001575 pathological effect Effects 0.000 description 6
- 239000003761 preservation solution Substances 0.000 description 6
- 206010008342 Cervix carcinoma Diseases 0.000 description 4
- 206010028980 Neoplasm Diseases 0.000 description 4
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 description 4
- 201000010881 cervical cancer Diseases 0.000 description 4
- 230000002380 cytological effect Effects 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 4
- 210000004291 uterus Anatomy 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000010827 pathological analysis Methods 0.000 description 3
- 238000004321 preservation Methods 0.000 description 3
- 210000003484 anatomy Anatomy 0.000 description 2
- 230000001680 brushing effect Effects 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 238000001574 biopsy Methods 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000028149 female reproductive system neoplasm Diseases 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
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Abstract
The utility model discloses an endometrium visual cell sampler, which consists of a sampling brush, a separation membrane, a guide tube and an endoscope; the endoscope consists of a probe, a guide shaft, a handle and a display screen, and the sampling brush is sleeved and fixed on the outer wall of the probe of the endoscope and is arranged in the guide pipe. When in use, the probe and the sampling brush are extended into the uterine cavity, the pathological change area of the endometrium is observed through the probe, and the endometrial cells are brushed by the sampling brush in the target area to obtain a diagnosis sample. The utility model provides a safe and effective technical method for screening endometrial cancer.
Description
Technical Field
The utility model belongs to the technical field of medical appliances, and particularly relates to an endometrium visible cell sampler.
Background
Endometrial cancer is one of the common gynaecological tumors, the incidence rate of the endometrial cancer is increased year by year, and along with the effective application of cytology and molecular technology in cervical cancer screening, the incidence rate of the endometrial cancer exceeds that of cervical cancer, and the endometrial cancer becomes a malignant tumor of which the incidence rate is inferior to that of breast cancer in female reproductive system tumors, but an effective screening means for the tumor is still lacking. At present, the clinically common endometrial pathological diagnosis methods comprise diagnostic uterine curettage, endometrial biopsy and the like, and the methods are large in wound and complex in operation, are suitable for diagnosing endometrial lesions, and are not suitable for screening endometrial cancers. By screening technology, early detection and early operation on tumors are the most effective methods for treating tumors, and the large reduction of the incidence rate and death rate of cervical cancer is benefited by the application of the large-scale screening technology of cervical cancer. Currently, there are endometrial cell collectors on the market, however, due to the special structure of uterus, including small cervical canal, enlarged uterine cavity and individual difference of uterine anatomy, these devices can only blindly obtain partial areas of endometrium, especially difficult to obtain cell samples of high-incidence parts of endometrial cancer, the specimens are not representative, and there are problems of insufficient materials, small cell quantity and the like, and there is still no effective and practical method for cytologically sampling and screening endometrial lesions in clinic.
Disclosure of Invention
The visual cell sampler for the endometrium is characterized by comprising a sampling brush, a separation membrane, a guide tube and an endoscope; the endoscope consists of a probe, a guide shaft, a handle and a display screen, wherein the handle is provided with a control rod, and an image detected by the probe can be observed on the display screen; the sampling brush and the isolating film are sequentially sleeved and fixed on the outer wall of the endoscope probe and are arranged in the guide pipe. The sampling brush can be made of metal, plastic, silica gel and other materials, and the outer side surface of the sampling brush is provided with bulges and depressions, and can also form a net structure; the sampling brush is directly fixed on the outer wall of the probe due to the lack of the isolating film, so that a similar technical effect can be achieved.
When in use, the isolating film and the sampling brush can be sequentially sleeved and fixed on the outer wall of the endoscope probe and placed in the guide pipe to assemble the cell sampler. Then, after the guide tube is extended into the internal opening of the cervical canal, the guide shaft is pushed forward to extend the probe and the sampling brush into the uterine cavity, the pathological change area of the endometrium is observed through the probe, the sampling brush is contacted with the endometrium in the target area and moves longitudinally, and endometrial cells are brushed to obtain a diagnosis sample.
Compared with the prior art, the utility model provides a novel endometrium visible cell sampler, which has the following beneficial technical effects: (1) The technology is used for sampling the cytological specimen of the endometrium under the visual condition, and can effectively solve the practical problems of difficult sampling such as small cervical canal, large uterine cavity, large difference of individual anatomy structures of the uterus and the like.
(2) The sampling under the visual condition can accurately sample the endometrium lesion area which is visible to the naked eye, and can simply obtain the lesion cells, so that the sampling is accurate.
(3) Can accurately sample the high-incidence part of endometrial cancer, such as cytological samples of the parts of uterine horns, uterine bottoms and the like.
(4) A smaller diameter cell sampler can be used, so that the patient does not need to dilate the cervical canal, and discomfort and pain in the sampling process are greatly reduced.
(5) The cytological specimens obtained by the method have sufficient quantity, and the high abundance of pathological cells (such as pathological cells) is beneficial to pathological diagnosis.
(6) The method can obtain macroscopic images of endometrium and microscopic forms of cells at the same time, and a doctor of a pathology department can refer to the images of endometrium when reading (cell slice or smear), thereby being beneficial to making accurate pathological diagnosis of diseases.
(7) The purpose of obtaining samples with different diagnosis requirements can be achieved by changing the sampling layer structure of the cell sampler.
(8) The technical method belongs to minimally invasive sampling, is safe and effective, and can not cause damage to patients.
Drawings
FIG. 1 is a schematic diagram of the structure of an endometrium visible cell sampler.
Fig. 2 is a schematic diagram of the structure of the endometrium visible cell sampler in the use state.
Description of the embodiments
For the purposes of making the objects, technical solutions and advantages of the present utility model more clearly apparent, it should be noted that the directions or positional relationships indicated by the terms "upper", "lower", "inner", "outer", etc. are based on the directions or positional relationships shown in the drawings, and are merely for convenience of description and simplification of description, and do not mean or imply that the apparatus or element in question must have a specific direction, and that "connected", "mounted", etc. should be construed broadly.
As shown in fig. 1, a schematic structural diagram of an endometrium visual cell sampler, the visual cell sampler is composed of a sampling brush 2, a separation membrane 3, a guide tube 4 and an endoscope 1; the endoscope 1 consists of a probe 11, a guide shaft 12, a handle 13 and a display screen 16, wherein the handle 13 is provided with a control rod 14 and is connected with the display screen 16 through a signal wire 15, and an image detected by the probe 11 can be observed on the display screen 16; the sampling brush 2 and the isolating film 3 are sequentially sleeved and fixed on the outer wall of the probe 11 of the endoscope 1 and are placed in the guide pipe 4. The sampling brush 2 can be made of metal, plastic, silica gel and other materials, and the outer side surface of the sampling brush is provided with bulges and depressions, and can also form a net structure; the sampling brush 2 is directly fixed on the outer wall of the probe 11 due to the lack of the isolating membrane 3, so that similar technical effects can be achieved.
As shown in figure 2, a structural schematic diagram of the use state of the endometrium visible cell sampler, when in use, the isolating membrane 3 and the sampling brush 2 can be sequentially sleeved and fixed on the outer wall of the probe 11 of the endoscope 1, and placed in the guide tube 4 to be assembled into the cell sampler; then, after the guide tube 4 is extended into the endocervical opening along the cervical canal, the probe 11 and the sampling brush 2 are extended into the uterine cavity by pushing the guide shaft 12 forward, the pathological region of the endometrium is observed through the probe 11, the sampling brush 2 is contacted with the endometrium in the target region and repeatedly moves longitudinally, and the endometrial cells are rubbed to obtain a diagnostic sample.
Embodiment one (reuse of the probe 11 of the endoscope 1): (1) The handle 13 of the endoscope 1 is held by hand, the isolating membrane 3 is sleeved on the probe 11 and the guide shaft 12 of the endoscope 1, then the sampling brush 2 is sleeved and fixed on the probe 11 and the isolating membrane 3, and is inserted into the guide tube 4 to assemble the endometrial cell sampler.
(2) After the guide tube 4 of the cell sampler is extended into the endocervical opening along the cervical canal, the probe 11 and the sampling brush 2 are extended into the uterine cavity by pushing the guide shaft 12 forward with the handle.
(3) The endometrium is observed on a display screen 16 through a probe 11, a possible lesion area is observed, after the lesion area is found, the positions of the probe 11 and a sampling brush 2 are moved by operating a handle 13 and a control lever 14 on the handle, and cells in the lesion area are brushed by the sampling brush 2.
(4) When the probe 11 is used to observe endometrium and the suspicious lesion area is not observed, the handle 13 and the operating lever 14 on the handle are moved, and the sampling brush 2 is used to brush cell samples at the uterine horn, uterine fundus, anterior and posterior walls of uterus and other parts.
(5) By moving the handle 13, the guide shaft 12 and the probe 11 are pulled back, the sampling brush 2 and the probe 11 are re-introduced into the lumen of the guide tube 4, and the whole endometrium visible cell sampler is withdrawn from the cervical canal.
(6) The handle 13 and the guide shaft 12 are pushed forward, the sampling brush is pushed out of the cavity of the guide tube 4, the sampling brush is stretched into the preservation solution of the cell preservation bottle, and the cells on the sampling brush 2 are eluted into the cell preservation solution for inspection.
(7) The isolation diaphragm 3 and the sampling brush 2 and the guide tube 4 thereon are removed from the probe 11 and the guide shaft 12 of the endoscope 1 and discarded.
Second embodiment (single use endoscope 1 probe 11): (1) The handle 13 of the endoscope 1 is held by hand, the sampling brush 2 is fixed on the probe 11 in a telescopic way and is inserted into the guide tube 4 to assemble the endometrium visible cell sampler.
(2) After the guide tube 4 of the visual cell sampler is extended into the endocervical opening along the cervical canal, the probe 11 and the sampling brush 2 are extended into the uterine cavity by pushing the guide shaft 12 forward.
(3) The endometrium is observed on a display screen through the probe 11, a possible pathological region is observed, after the pathological region is found, the positions of the probe 11 and the sampling brush 2 are moved through the operation handle 13 and the operating rod 14 on the handle, and the sampling brush 2 is used for brushing cells and sampling the pathological region preferentially.
(4) When the endometrium is observed through the probe 11, if the suspicious lesion area is not found, the handle 13 and the control rod 14 on the handle are moved, and the cytological specimens are respectively brushed at the uterine horn, the uterine fundus, the anterior wall, the posterior wall and the like by the sampling brush 2.
(5) The guide shaft 12 and the probe 11 are moved by the handle 13, the sampling brush 2 and the probe 11 are re-introduced into the chamber of the guide tube 4, and the endometrial visual cell sampler is withdrawn from the cervical canal.
(6) The handle 13 and the guide shaft 12 are pushed forward, the sampling brush 2 is pushed out of the cavity of the guide tube 4, the sampling brush 2 is stretched into the preservation solution of the cell preservation bottle, and the cells on the sampling brush 2 are eluted into the cell preservation solution.
(7) The guide shaft 12 on the handle 13 is removed, and the probe 11 and the sampling brush 2 connected thereto are discarded.
Embodiment three (disinfection reusable endoscope 1 probe 11): (1) The sampling brush 2 is sleeved and fixed on the outer wall of the probe 11 and is placed in the guide tube 4 to assemble the endometrium visible cell sampler.
(2) After the guide tube 4 of the cell sampler is extended into the endocervical opening along the cervical canal, the probe 11 and the sampling brush 2 are extended into the uterine cavity by pushing the guide shaft 12 forward.
(3) The endometrium is observed through the probe 11, a possible lesion area is observed, after the lesion area is found, the positions of the probe 11 and the sampling brush 2 are moved by moving the handle 13 and the operating lever 14 on the handle, and the cells of the lesion area are brushed by the sampling brush 2.
(4) The endometrium is observed through the probe 11, the suspicious lesion area is not seen, the handle 13 and the control rod 14 on the handle are moved, and the sampling brush 2 is used for brushing cells at the uterine horn, the uterine fundus, the anterior wall, the posterior wall and the like of the uterus respectively.
(5) By moving the handle 13, the guide shaft 12 and the probe 11 are pulled back, the sampling brush 2 and the probe 11 are accommodated in the lumen of the guide tube 4, and the endometrial visual cell sampler is withdrawn from the cervical canal.
(6) The handle 13 and the guide shaft 12 are pushed forward, the sampling brush 2 is pushed out of the cavity of the guide tube 4, the sampling brush 2 is stretched into the preservation solution of the cell preservation bottle, and the cells on the outer wall of the sampling brush 2 are eluted into the cell preservation solution for inspection.
(7) The guide shaft 12 on the handle 13, the probe 11 connected with the guide shaft and the sampling brush 2 are taken down, and the sampling brush is reassembled for use after cleaning and disinfection.
Claims (3)
1. An endometrium visible cell sampler is characterized by comprising a sampling brush, a separation membrane, a guide tube and an endoscope; the endoscope consists of a probe, a guide shaft, a handle and a display screen, and can observe images detected by the probe on the display screen; the sampling brush and the isolating film are sequentially sleeved and fixed on the outer wall of the endoscope probe, and the isolating film is positioned between the cell sampling brush and the endoscope probe and is arranged in the guide pipe; after the cell sampler is extended to the cervical internal opening, the probe and the sampling brush are extended into the uterine cavity, the endometrial wall is observed through the probe, the sampling brush is contacted with the endometrial wall in a target area and moves longitudinally, and the endometrial cells are rubbed to obtain a diagnostic sample.
2. An endometrium visible cell sampler as claimed in claim 1 wherein the cell sampling brush is made of metal, plastic or silica gel material and has protrusions and depressions on its outer surface, and may be in a mesh structure.
3. An endometrium visible cell sampler as claimed in claim 1 wherein the absence of a barrier membrane of the cell sampler achieves the same technical result.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320497587.6U CN220459374U (en) | 2023-03-15 | 2023-03-15 | Visual cell sampler of endometrium |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320497587.6U CN220459374U (en) | 2023-03-15 | 2023-03-15 | Visual cell sampler of endometrium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220459374U true CN220459374U (en) | 2024-02-09 |
Family
ID=89799500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320497587.6U Active CN220459374U (en) | 2023-03-15 | 2023-03-15 | Visual cell sampler of endometrium |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220459374U (en) |
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2023
- 2023-03-15 CN CN202320497587.6U patent/CN220459374U/en active Active
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