CN220443469U - Serpentine exhaust pipe and sterilization filter applying same - Google Patents
Serpentine exhaust pipe and sterilization filter applying same Download PDFInfo
- Publication number
- CN220443469U CN220443469U CN202320583369.4U CN202320583369U CN220443469U CN 220443469 U CN220443469 U CN 220443469U CN 202320583369 U CN202320583369 U CN 202320583369U CN 220443469 U CN220443469 U CN 220443469U
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- China
- Prior art keywords
- silica gel
- gel pipeline
- filter
- pipeline
- exhaust pipe
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- 230000001954 sterilising effect Effects 0.000 title claims abstract description 48
- WYTGDNHDOZPMIW-RCBQFDQVSA-N alstonine Natural products C1=CC2=C3C=CC=CC3=NC2=C2N1C[C@H]1[C@H](C)OC=C(C(=O)OC)[C@H]1C2 WYTGDNHDOZPMIW-RCBQFDQVSA-N 0.000 title claims abstract description 13
- 238000004659 sterilization and disinfection Methods 0.000 title claims description 22
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 78
- 239000000741 silica gel Substances 0.000 claims abstract description 78
- 229910002027 silica gel Inorganic materials 0.000 claims abstract description 78
- 239000007788 liquid Substances 0.000 claims abstract description 48
- 229920000742 Cotton Polymers 0.000 claims abstract description 34
- 241000894006 Bacteria Species 0.000 abstract description 8
- 238000009395 breeding Methods 0.000 abstract description 7
- 230000001488 breeding effect Effects 0.000 abstract description 7
- 239000001963 growth medium Substances 0.000 abstract description 5
- 229960000074 biopharmaceutical Drugs 0.000 abstract description 2
- 238000001914 filtration Methods 0.000 description 9
- 230000000694 effects Effects 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- 241000270295 Serpentes Species 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 238000009987 spinning Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 238000001471 micro-filtration Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/20—Air quality improvement or preservation, e.g. vehicle emission control or emission reduction by using catalytic converters
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- Filtering Materials (AREA)
Abstract
The utility model relates to the technical field of biopharmaceutical sterilizing filters, in particular to a snake-shaped exhaust pipe and a sterilizing filter using the same. A snake-shaped exhaust pipe comprises a silica gel pipeline, wherein one end of the silica gel pipeline is connected with a sterilizing filter, and the other end of the silica gel pipeline is connected with an air filter; the silica gel pipeline comprises a silica gel pipeline body, wherein a line capable of adsorbing liquid drops is arranged in the silica gel pipeline body, and the line extends along the length direction of the silica gel pipeline body. The utility model provides a sterile external environment for the sterilizing filter, so that bacteria breeding at the exhaust port of the sterilizing filter is avoided, and the inside of the sterilizing filter is polluted; the environment of the clean room is protected, and bacteria are prevented from breeding in the environment when the culture medium is sprayed into the environment. The serpentine exhaust pipe occupies a small area, saves precious space in a test area, and is safe to use and convenient to operate. The cotton thread in the silica gel pipeline is equivalent to a liquid drop capturing device, and can use the shorter silica gel pipeline to retain more liquid, so that the service life is longer.
Description
Technical Field
The utility model relates to the technical field of biopharmaceutical sterilizing filters, in particular to a snake-shaped exhaust pipe and a sterilizing filter using the same.
Background
In the fields of biological medicine and food production, the sterilization and filtration are becoming a general technology, and the sterilization and filtration mainly adopts a micro-filtration filter element with large specific surface area and filtration precision of more than 0.22 mu m, and is mainly used for preventing impurities, harmful bacteria, microorganisms and the like in the air from entering a tank body, a production line, a sterile room and the like, causing the change of water quality, products and the environment of the sterile room and meeting the requirements of biological medicine technology.
The sterilization filter membrane needs to be fully wetted when in use, liquid in the filter core needs to be emptied before high-pressure sterilization, and the liquid is fully infiltrated behind the filter by exhausting through an exhaust port when in use, so that the sterilization filter can be performed. If air is trapped in the filter housing, the filter membrane at the air blocking part cannot work, so that the exhaust is a necessary step in the sterilization and filtration process.
The current method of exhausting the sterilizing filter is to directly exhaust or use an exhaust gas bottle/gas collecting bottle, the exhaust gas is easy to pollute the clean indoor environment when directly exhausting, and the gas collecting bottle needs a certain space and occupies the area of an operating platform. When a bioreactor is used for culturing cells, a culture medium is often used for perfusion culture through filtration of a sterilizing filter, a small 5-inch filter core is usually used, and air fused into the liquid can be redissolved to form bubbles due to temperature change of the culture medium in the use process, so that frequent exhaust is often required. Meanwhile, due to the fact that a large number of pipelines exist around the bioreactor, many operations often exist around the bioreactor, and a fragile gas collection bottle is not suitable for the application scene.
Disclosure of Invention
Based on the above, the utility model aims to provide a snake-shaped exhaust pipe and a sterilization filter using the same, which provide a sterile external environment for the sterilization filter and avoid bacteria breeding at an exhaust port of the filter and polluting the inside of the filter.
The technical scheme of the utility model is as follows: the serpentine exhaust pipe comprises a silica gel pipeline, wherein one end of the silica gel pipeline is connected with a sterilizing filter, and the other end of the silica gel pipeline is connected with an air filter;
the silica gel pipeline include silica gel pipeline body, this internal line that can adsorb the liquid droplet that is equipped with of silica gel pipeline, the line extend along the length direction of silica gel pipeline body.
In the utility model, in the exhaust process, the gas can carry a large number of tiny liquid drops to pass through the silica gel pipeline, and the liquid drops can be captured by the line and fixed in the line when flying in the silica gel pipeline, so that the air filter is prevented from being blocked after the liquid drops are flushed into the air filter.
In a further technical scheme of the utility model, the lines are cotton lines. Cotton thread (cotton thread) is a kind of daily necessities, and is a slender and random-bendable thread which is made up by using cotton fibre through the process of twisting and spinning. The cotton thread is equivalent to a liquid drop catching device, plays the role of absorbing liquid drops, has low cost, can use a shorter silica gel pipeline to retain more liquid, and has longer service life.
In a further technical scheme of the utility model, the diameter of the cotton thread is smaller than 1/4 of the diameter of the silica gel pipeline. The cotton thread diameter is suitable with the diameter proportion of the silica gel pipeline, if the diameter of the cotton thread is too large, the silica gel pipeline is easy to be blocked, and if the diameter of the cotton thread is too small, the effect of absorbing and capturing liquid drops is difficult to be achieved, so that the diameter of the cotton thread is suitable with the proportion of less than 1/4 of the diameter of the silica gel pipeline.
In a further technical scheme of the utility model, the length of the cotton thread is smaller than that of the silica gel pipeline. Because degerming filter and air cleaner are connected respectively at the both ends of silica gel pipeline, if the length of cotton thread is greater than the length of silica gel pipeline, can influence the fixed effect of silica gel pipeline and degerming filter, air cleaner.
In a further technical scheme of the utility model, the silica gel pipeline is soft silica gel. The silica gel pipeline is soft silica gel, and the silica gel pipeline is bendable and foldable, is similar to a snake shape, occupies a small area, saves precious space in a test area, and is safe to use and convenient to operate. Meanwhile, the length is variable, and the proper length and placement form can be selected according to the conditions of the production environment and the actual use requirements.
In a further technical scheme, the utility model also provides a sterilization filter, wherein the serpentine exhaust pipe comprises a sterilization filter body, the top of the sterilization filter body is provided with an exhaust pipe, and the exhaust pipe is connected with one end of a silica gel pipeline;
the side part upper end of the degerming filter body is provided with a liquid inlet pipeline, the degerming filter body is internally provided with a filter element, and the bottom of the degerming filter body is provided with a liquid outlet pipeline.
Specifically, the exhaust pipe is provided with a plunger valve. The liquid outlet pipeline is provided with a valve.
In the process of sterilization and filtration, the plunger valve is opened, the valve of the liquid outlet pipeline is closed, liquid enters from the liquid inlet pipeline, gas is discharged from the exhaust pipe, flows through the silica gel pipeline and is discharged after being filtered by the air filter. Cotton threads arranged in the silica gel pipeline can effectively capture liquid drops in the gas.
In a further technical scheme of the utility model, in the degerming filter body, the height of a connecting port of the liquid inlet pipeline and the degerming filter body is larger than that of the filter element. The bottom of the degerming filter body is also provided with a bracket.
The height relation between the liquid inlet pipeline and the filter element enables the filtering effect to be better, and the bracket plays a role in supporting the sterilizing filter body.
Compared with the prior art, the beneficial effects are that:
1. the aseptic environment is provided for the aseptic filter, so that bacteria breeding at the exhaust port of the aseptic filter is avoided, and the interior of the aseptic filter is polluted; the environment of the clean room is protected, and bacteria are prevented from breeding in the environment when the culture medium is sprayed into the environment.
2. The serpentine exhaust pipe occupies a small area, saves precious space in a test area, and is safe to use and convenient to operate. Meanwhile, the length is variable, and the proper length and placement form can be selected according to the conditions of the production environment and the actual use requirements.
3. The cotton thread in the silica gel pipeline is equivalent to a liquid drop capturing device, and can use the shorter silica gel pipeline to retain more liquid, so that the service life is longer.
For a better understanding and implementation, the present utility model is described in detail below with reference to the drawings.
Drawings
Fig. 1 is a schematic overall view of the present utility model.
Detailed Description
In order that the objects, features and advantages of the utility model will be readily understood, a more particular description of the utility model will be rendered by reference to specific embodiments thereof which are illustrated in the appended drawings. Several embodiments of the utility model are presented in the figures. This utility model may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein.
In the present utility model, unless explicitly specified and limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present utility model can be understood by those of ordinary skill in the art according to the specific circumstances. The terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include one or more such feature.
In the present utility model, unless expressly stated or limited otherwise, a first feature "above" or "below" a second feature may include both the first and second features being in direct contact, as well as the first and second features not being in direct contact but being in contact with each other through additional features therebetween. Moreover, a first feature being "above," "over" and "on" a second feature includes the first feature being directly above and obliquely above the second feature, or simply indicating that the first feature is higher in level than the second feature. The first feature being "under", "below" and "beneath" the second feature includes the first feature being directly under and obliquely below the second feature, or simply means that the first feature is less level than the second feature. The terms "vertical," "horizontal," "left," "right," "up," "down," and the like are used for descriptive purposes only and are not to indicate or imply that the devices or elements being referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the utility model.
The present utility model will be described in detail below with reference to the accompanying drawings and examples.
As shown in fig. 1, the serpentine exhaust pipe comprises a silica gel pipeline 2, wherein one end of the silica gel pipeline 2 is connected with a sterilizing filter, and the other end of the silica gel pipeline 2 is connected with an air filter 1;
the silica gel pipeline 2 comprises a silica gel pipeline body 22, a line capable of adsorbing liquid drops is arranged in the silica gel pipeline body 22, and the line extends along the length direction of the silica gel pipeline body 22.
In this embodiment, during the exhaust process, the gas will pass through the silica gel pipe 2 with a large number of fine droplets, and the droplets will be captured by the wire and fixed in the wire when flying in the silica gel pipe 2, thus avoiding the droplets from blocking the air filter 1 after being flushed into the air filter 1.
In this embodiment, the line is cotton thread 21. The cotton thread 21 is an elongated, arbitrarily bendable thread made of cotton fibers by spinning. The cotton thread is equivalent to a liquid drop catching device, plays the role of absorbing liquid drops, has low cost, can use the shorter silica gel pipeline 2 to retain more liquid, and has longer service life.
In addition, the silica gel pipe 2 is soft silica gel. The silica gel pipeline 2 is soft silica gel, and the silica gel pipeline 2 is bendable and foldable, is similar to a snake shape, has small occupied area, saves precious space in a test area, and is safe to use and convenient to operate. Meanwhile, the length is variable, and the proper length and placement form can be selected according to the conditions of the production environment and the actual use requirements.
So the soft silica gel pipeline 2 and the cotton thread 21 are combined with each other to form a snake-shaped exhaust pipe, and the snake-shaped exhaust pipe can be wound into a roll or folded, so that the use is convenient and the occupied space is small.
Specifically, the cotton thread 21 has a diameter smaller than 1/4 of the diameter of the silicone tube 2. If the diameter of the cotton thread 21 is too large, the silica gel pipe 2 is likely to be blocked, and if the diameter of the cotton thread 21 is too small, the effect of adsorbing and capturing liquid drops is difficult to be achieved, so that the diameter of the cotton thread 21 is smaller than the 1/4 of the diameter of the silica gel pipe 2 in a proper ratio.
Still further, the length of the cotton thread 21 is smaller than the length of the silicone tube 2. Since the two ends of the silica gel pipe 2 are respectively connected with the sterilizing filter and the air filter 1, if the length of the cotton thread 21 is greater than that of the silica gel pipe 2, the fixing effect of the silica gel pipe 2 and the sterilizing filter and the air filter 1 can be affected.
In the embodiment, a sterilization filter is further provided, wherein a serpentine exhaust pipe is applied, the sterilization filter comprises a sterilization filter body 8, the top of the sterilization filter body 8 is provided with an exhaust pipe, and the exhaust pipe is connected with one end of the silica gel pipeline 2;
the upper end of the side part of the sterilizing filter body 8 is provided with a liquid inlet pipeline 4, a filter element 5 is arranged inside the sterilizing filter body 8, and a liquid outlet pipeline 6 is arranged at the bottom of the sterilizing filter body 8.
The exhaust pipe is provided with a plunger valve 3, and the liquid outlet pipe 6 is provided with a valve 7.
Still further, in the degerming filter body 8, the height of the connecting port between the liquid inlet pipeline 4 and the degerming filter body 8 is larger than the height of the filter element 5. The bottom of the sterilizing filter body 8 is also provided with a bracket.
In this embodiment, the height relationship between the liquid inlet pipe 4 and the filter element 5 makes the filtering effect better, and the bracket plays a role in supporting the sterilizing filter body 8.
The working principle of the utility model is as follows:
in the process of sterilization and filtration, the plunger valve 3 is opened, the valve 7 of the liquid outlet pipeline is closed, liquid enters from the liquid inlet pipeline 4, gas is discharged from the exhaust pipe, flows through the silica gel pipeline 2 and is discharged after being filtered by the air filter 1. Cotton threads 21 installed in the silica gel pipe 2 can effectively capture liquid drops in the gas. The cotton thread 21 can be directly arranged in the silica gel pipeline 2, and the cotton thread 21 can be adhered to the pipe wall after absorbing liquid drops, and as the two ends of the silica gel pipeline 2 are respectively connected with the sterilizing filter and the air filter, the cotton thread 21 can effectively capture the liquid drops in the silica gel pipeline 2.
The utility model has the following technical effects:
1. the aseptic environment is provided for the aseptic filter, so that bacteria breeding at the exhaust port of the aseptic filter is avoided, and the interior of the aseptic filter is polluted; the environment of the clean room is protected, and bacteria are prevented from breeding in the environment when the culture medium is sprayed into the environment.
2. The serpentine exhaust pipe occupies a small area, saves precious space in a test area, and is safe to use and convenient to operate. Meanwhile, the length is variable, and the proper length and placement form can be selected according to the conditions of the production environment and the actual use requirements.
3. The cotton thread in the silica gel pipeline is equivalent to a liquid drop capturing device, and can use the shorter silica gel pipeline to retain more liquid, so that the service life is longer.
It is to be understood that the above examples of the present utility model are provided by way of illustration only and not by way of limitation of the embodiments of the present utility model. Other variations or modifications of the above teachings will be apparent to those of ordinary skill in the art. It is not necessary here nor is it exhaustive of all embodiments. Any modification, equivalent replacement, improvement, etc. which come within the spirit and principles of the utility model are desired to be protected by the following claims.
Claims (10)
1. The snakelike exhaust pipe is characterized by comprising a silica gel pipeline (2), wherein one end of the silica gel pipeline (2) is connected with a sterilizing filter, and the other end of the silica gel pipeline is connected with an air filter;
the silica gel pipeline (2) comprises a silica gel pipeline body (22), wherein a line capable of adsorbing liquid drops is arranged in the silica gel pipeline body (22), and the line extends along the length direction of the silica gel pipeline body (22).
2. A serpentine exhaust tube according to claim 1, wherein: the lines are cotton lines (21).
3. A serpentine exhaust tube according to claim 2, wherein: the diameter of the cotton thread (21) is smaller than 1/4 of the diameter of the silica gel pipeline (2).
4. A serpentine exhaust tube according to claim 3, wherein: the length of the cotton thread (21) is smaller than that of the silica gel pipeline (2).
5. A serpentine exhaust tube according to claim 4, wherein: the silica gel pipeline (2) is soft silica gel.
6. The sterilization filter is characterized by comprising a sterilization filter body (8), wherein the top of the sterilization filter body (8) is provided with an exhaust pipe, and the exhaust pipe is connected with one end of a silica gel pipeline (2);
the side part upper end of the degerming filter body (8) is provided with a liquid inlet pipeline (4), a filter element (5) is arranged inside the degerming filter body (8), and the bottom of the degerming filter body (8) is provided with a liquid outlet pipeline (6).
7. A sterilizing filter according to claim 6 wherein: and a plunger valve (3) is arranged on the exhaust pipe.
8. A sterilizing filter according to claim 6 wherein: the liquid outlet pipeline (6) is provided with a valve (7).
9. A sterilizing filter according to claim 6 wherein: in the degerming filter body (8), the height of a connecting port between the liquid inlet pipeline (4) and the degerming filter body (8) is larger than that of the filter element (5).
10. A sterilizing filter according to claim 6 wherein: the bottom of the degerming filter body (8) is also provided with a bracket.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320583369.4U CN220443469U (en) | 2023-03-21 | 2023-03-21 | Serpentine exhaust pipe and sterilization filter applying same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320583369.4U CN220443469U (en) | 2023-03-21 | 2023-03-21 | Serpentine exhaust pipe and sterilization filter applying same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220443469U true CN220443469U (en) | 2024-02-06 |
Family
ID=89733909
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320583369.4U Active CN220443469U (en) | 2023-03-21 | 2023-03-21 | Serpentine exhaust pipe and sterilization filter applying same |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220443469U (en) |
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2023
- 2023-03-21 CN CN202320583369.4U patent/CN220443469U/en active Active
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