CN220424356U

CN220424356U - Plug-in type percutaneous administration device

Info

Publication number: CN220424356U
Application number: CN202222897464.XU
Authority: CN
Inventors: 陈刚; 王梅林
Original assignee: Beijing Sinohanfang Pharmaceutical Sci& Tech Co ltd
Current assignee: Beijing Sinohanfang Pharmaceutical Sci& Tech Co ltd
Priority date: 2022-11-01
Filing date: 2022-11-01
Publication date: 2024-02-02
Anticipated expiration: 2032-11-01

Abstract

The present application relates to the field of percutaneous, i.e. transdermal, drug delivery, and more particularly to a plug-in transdermal drug delivery device. In some embodiments of the present application, the tray body assembly and the tray cover assembly are detachably connected by the plug-in combination and the detachment separation of the first electrical plug-in unit and the second electrical plug-in unit, and the tray body assembly in contact with the skin can be independently sterilized after the treatment is finished, for example, the tray body assembly is sterilized by boiling in water, so that the biological safety of the next use is ensured. In other embodiments of the present application, a gas inlet and a gas outlet are provided on the support, and the gas inlet and the gas outlet are communicated with the space formed by the support and the second socket and the inside of the tray cover body, so as to prevent the second electric plug rod from being difficult to be inserted into the second electric plug cylinder due to the compression of air in the space formed by the support and the second socket.

Description

Plug-in type percutaneous administration device

Technical Field

The present application relates to the field of percutaneous, i.e. transdermal, drug delivery, and more particularly to a plug-in transdermal drug delivery device.

Background

Transdermal drug delivery is an effective method for treating diseases by introducing the drug into the body through skin permeation, and the drug in the use process enters the lesion part or acupoint of the human body through skin to play a role, so that the damage of oral drug to the gastrointestinal tract can be avoided. However, the skin of the human body has a very compact structure, and the medicine is quite resistant to permeation through the skin, so that the medicine is difficult to achieve the required therapeutic dose. The following two means can increase the transdermal rate of the drug and increase the transdermal penetration amount of the drug: firstly, the heating can raise the temperature of the skin at the medicine applying part, quicken the local blood circulation, increase the permeability of the skin, provide physiological environment for the transdermal entry of medicine, and promote the release of volatile components of the medicine; the second is to close the local space (administration space) where the drug is located to create as high transdermal drug delivery kinetics as possible.

In the prior art, after the percutaneous administration device is used, in order to avoid damaging electronic elements, alcohol cotton balls are generally used for wiping and sterilizing. With the increasing number of sterilization modes, there is a need to provide products with richer sterilization modes.

Disclosure of Invention

In view of this, the present application provides a plug-in type transdermal drug delivery device, so as to solve one or more technical problems in the prior art, and the present application is implemented as follows:

in a first aspect, embodiments of the present application provide a plug-in transdermal drug delivery device comprising:

a tray assembly, the tray assembly comprising:

the disc body is provided with a central cavity and an annular negative pressure annular cavity, and the negative pressure annular cavity is provided with an air guide elbow joint;

the tray body cover is connected with the tray body and is arranged above the central cavity;

an electronic element comprising an electrical heating element located on the tray and above the central cavity to indirectly heat the central cavity;

a first seal member connected to the tray body, the first seal member sealing the electronic component from water;

a first electrical plug-in unit, which is in sealing connection with the first sealing element, wherein the top of the first electrical plug-in unit extends out of the first sealing element, and the bottom of the first electrical plug-in unit is electrically connected with the electronic element;

a tray cover assembly disposed on the tray body assembly, the tray cover assembly comprising:

the disc cover body is used for covering the first sealing element and is in sealing connection with the first sealing element; the side face of the tray cover body is provided with an air guide pipe joint and an air guide elbow joint, the air guide pipe joint is used for being connected with an external air extractor through an air guide pipe, the air guide pipe joint is used for forming ventilation connection with the air guide elbow joint, and the air guide elbow joint is used for forming ventilation connection with the air guide elbow joint;

the second electric plug-in is connected with the disc cover body and arranged in the disc cover body, and is electrically connected with an external power supply;

the first electric plug-in unit is in friction connection with the second electric plug-in unit when in plug-in connection, the tray body component and the tray cover component are mutually combined when the first electric plug-in unit is in plug-in connection with the second electric plug-in unit so as to prevent the tray cover component from falling off from the tray body component, and the tray body component and the tray cover component are mutually separated to sterilize the tray body component when the first electric plug-in unit is detached from the second electric plug-in unit.

In some embodiments, the first electrical insert is a first electrical cartridge and the second electrical insert is a first electrical insert so that the first electrical insert is inserted into the first electrical cartridge with the opposite hole viewed from above; when the first electric plug rod is inserted into the first electric plug cylinder, the disc body assembly and the disc cover assembly are combined with each other, and when the first electric plug rod is separated from the first electric plug cylinder, the disc body assembly and the disc cover assembly are separated from each other; or (b)

The first electric plug is a second electric plug, and the second electric plug is a second electric plug cylinder, so that residual liquid on the second electric plug can be cleaned after the tray body assembly is disinfected; when the second electric plug rod is inserted into the second electric plug cylinder, the disc body component and the disc cover component are mutually combined, and when the second electric plug rod is separated from the second electric plug cylinder, the disc body component and the disc cover component are mutually separated.

In some embodiments, the first electrical insert is an electrical plunger and the second electrical insert is an electrical cartridge to facilitate cleaning of residual liquid on the electrical plunger after the tray assembly is retorted;

the tray body assembly is combined with the tray cover assembly when the electric plunger is inserted into the electric socket, and the tray body assembly is separated from the tray cover assembly when the electric plunger is separated from the electric socket.

In some embodiments, the first seal comprises a tray cover, a first receptacle, wherein,

the disc cover is provided with an annular groove with an opening facing the center of the disc cover, and the first plug seat is inserted into the annular groove and is connected with the annular groove in an adhesive manner so as to seal the disc cover and the first plug seat; or (b)

The first plug seat forms an annular groove with an opening facing the edge of the disc body cover, and the disc body cover is inserted into the annular groove and is connected with the annular groove in an adhesive mode so that the disc body cover is sealed with the first plug seat.

the tray body cover is provided with a tray body cover ring groove with an upward opening, the first plug seat is provided with a downward extending edge, and the edge is inserted into the tray body cover ring groove and is connected with the first plug seat in an adhesive mode so that the tray body cover is sealed with the first plug seat.

the tray cover is provided with a tray cover flange, the first plug seat is provided with a first plug seat flange, and the fastener is sleeved on the tray cover flange and the first plug seat flange so as to seal the tray cover and the first plug seat.

In some embodiments, the air guide conduit joint forms an air vent connection with the air guide elbow joint, comprising:

the air guide conduit joint and the air guide elbow an air pipe is connected between the joints to form ventilation connection; or (b)

The tray cover body is used for covering the first sealing piece and is in sealing connection with the first sealing piece so as to enable the air guide conduit joint and the air guide elbow joint to form ventilation connection; when the air guide conduit joint and the air guide elbow joint form ventilation connection, a negative pressure space is formed in the tray cover body, so that sealing force between the tray cover body and the first sealing piece is increased to prevent the tray cover body from falling off from the first sealing piece.

the outer surface of the first plug seat is provided with a groove with an outward opening, a sealing ring is arranged in the groove, and the disc cover body is in sealing connection with the first plug seat by abutting against the sealing ring; or (b)

The novel socket comprises a first socket body and is characterized in that a first socket annular groove with an upward opening is formed in the first socket body, a U-shaped sealing ring with an upward opening is arranged in the first socket annular groove, and the disc cover body is inserted into the U-shaped sealing ring to be in sealing connection with the first socket body.

In some embodiments, the first electrical insert is a first electrical cartridge and the second electrical insert is a first electrical insert so that the first electrical insert is inserted into the first electrical cartridge with the opposite hole viewed from above; the bottom end of the first electric plug cylinder is sealed to prevent liquid from being in contact with the electronic element and short-circuited, and an exhaust channel is formed in the first electric plug rod to prevent the first electric plug rod from being difficult to insert into the first electric plug cylinder due to the fact that the first electric plug rod compresses air in the first electric plug cylinder; or (b)

The first electric plug is a second electric plug, and the second electric plug is a second electric plug cylinder, so that residual liquid on the second electric plug can be cleaned after the tray body assembly is steamed and disinfected; the top end of the second electric plug cylinder is provided with a through hole so as to prevent the second electric plug rod from compressing air in the second electric plug cylinder to cause that the second electric plug rod is difficult to insert into the second electric plug cylinder.

In a second aspect, embodiments of the present application provide a method of using a plug-in transdermal drug delivery device, comprising:

the medicine pad is sleeved on the central convex column in the central cavity;

combining the tray cover assembly with the tray body assembly: connecting the first electrical plug-in with the second electrical plug-in;

air is extracted through an air guide pipe joint of the disc cover assembly, and negative pressure is formed in the disc cover body and a negative pressure annular cavity arranged on the disc body;

adsorbing the negative pressure ring cavity on the skin;

indirectly heating the central cavity by an electric heating element to cause a temperature increase in the central cavity to promote passage of drug molecules of the drug pad through the skin;

the temperature sensing element is connected with the electric heating element to detect the temperature of the electric heating element;

after the treatment is finished, the tray cover assembly is separated from the tray body assembly, and the tray body assembly is steamed and disinfected for the next use.

The beneficial effects that this application some embodiments bring are: the tray body component and the tray cover component are detachably connected through the plug-in combination and the disassembly separation of the first electric plug-in component and the second electric plug-in component, and the tray body component contacted with the skin can be independently disinfected after treatment is finished, for example, the biological safety in the next use is ensured.

In some embodiments of the present application, the first sealing member in the tray body assembly seals the electronic component so as to prevent water, so that the electronic component is always in an isolated state with disinfection liquids such as water and alcohol when the electronic component is boiled and disinfected in hot water, and short-circuit damage caused by dipping water on the electronic component when the electronic component is used next time is prevented.

In some embodiments of the present application, the both sides of first grafting seat annular groove are provided with towards the arch of disk cover body, and the sealed top of U-shaped ring offsets with the arch, can prevent like this that the disk cover body from taking out first grafting seat annular groove with the sealed U-shaped ring when taking out, reduced the damage rate of grafting formula percutaneous administration device.

In some embodiments of the present application, the support is provided with a gas inlet and a gas outlet, and the gas inlet and the gas outlet are communicated with the space formed by the support and the second socket and the inside of the tray cover body, so as to prevent the second electric plug rod from being difficult to be inserted into the second electric plug cylinder due to the compression of air in the space formed by the support and the second socket.

It should be understood that the description of this section is not intended to identify key or critical features of the embodiments of the application or to delineate the scope of the application. Other features of the present application will be described by and will be readily understood from the description of (2). The above, as well as additional objectives, advantages, and features of the present application will become apparent to those skilled in the art from the following detailed description of a specific embodiment of the present application when read in conjunction with the accompanying drawings.

Drawings

Some specific embodiments of the present application will be described in detail hereinafter by way of example and not by way of limitation with reference to the accompanying drawings, which serve to better understand the present solution and are not to be construed as limiting the present application. The same reference numbers will be used throughout the drawings to refer to the same or like parts or portions. It will be appreciated by those skilled in the art that the drawings are not necessarily drawn to scale. In the accompanying drawings:

FIG. 1 is a schematic top view of a plug-in transdermal drug delivery device according to some embodiments of the present application;

FIG. 2 is a cross-sectional view A-A of FIG. 1 in accordance with some embodiments of the present application;

FIG. 3 is a cross-sectional view B-B of FIG. 1 in accordance with some embodiments of the present application;

FIG. 4 is a schematic view of a disc cover assembly according to some embodiments of the present application;

FIG. 5 is a schematic view of a tray assembly according to some embodiments of the present application;

FIG. 6 is an isometric view of an electrical plunger according to some embodiments of the present application;

FIG. 7 is a cross-sectional view A-A of FIG. 1 according to further embodiments of the present application;

FIG. 8 is a cross-sectional view B-B of FIG. 1 according to further embodiments of the present application;

FIG. 9 is a schematic view of a disc cover assembly according to further embodiments of the present application;

FIG. 10 is a schematic view of a tray assembly according to further embodiments of the present application;

FIG. 11 is a schematic illustration of a seal ring according to some embodiments of the present application;

FIG. 12 is a cross-sectional view A-A of FIG. 1 in accordance with further embodiments of the present application;

FIG. 13 is a cross-sectional view B-B of FIG. 1 in accordance with further embodiments of the present application;

FIG. 14 is a schematic view of a U-shaped seal ring according to some embodiments of the present application;

fig. 15 is a flow chart illustrating a method of using a plug-in transdermal drug delivery device according to some embodiments of the present application.

Description of main reference numerals:

10-a tray assembly;

11-disc body, 111-negative pressure annular cavity, 112-central cavity, 113-central convex column and 114-air guide elbow joint;

12-disc cover, 121-disc cover inner edge, 122-disc cover ring groove, 123-disc cover flange, 124-disc cover seal, 124A-seal ring, 124B-U-seal ring, 124C-fastener;

13-an electric heating element;

14-a temperature sensing element, 141-a pin;

15-an inner wire;

16-a first socket, 161-a first socket outer edge, 162-a first socket annular groove;

17-first electrical plug, 171-second electrical plug, 172-first electrical cartridge;

20-a tray cover assembly;

21-a disc cover body, 211-an air guide pipe joint, 212-an electric guide pipe joint, 213-an air guide elbow joint and 214-a support;

22-conduit, 221-air guide conduit; 222-conductive conduits;

23-a second socket;

24-second electrical plug, 241-second electrical cartridge, 242-first electrical plug, 242A-vent channel;

30-an air guide elbow.

Detailed Description

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present application, where: many details of the embodiments of the present application are provided to facilitate understanding, the described embodiments are merely possible technical implementations of the present application, which should be considered as merely exemplary, not all implementations possible. Also, for the sake of clarity and conciseness, descriptions of well-known functions and constructions are omitted in the following description.

The use of ordinal numbers such as "first," "second," and the like in the description and in the claims, to modify a corresponding element does not by itself connote any ordinal number of that element, nor does it represent the order in which an element is ordered from another element, or the order in which it is manufactured, and use of such ordinal numbers merely serves to distinguish one element having a certain name from another element having the same name. In this application, "or/and", "and/or" means at least one of the objects, and "or" means one of the objects.

The terms "upper," "lower," "vertical," "high," "low" and "upper" are used herein with reference to fig. 2, and are used primarily for better describing the present application and its embodiments, and are not intended to limit the indicated device, element or component to a particular orientation or to be constructed and operated in a particular orientation. The term "plurality" shall mean two as well as more than two. The orientation or positional relationship indicated by the terms "inner", "outer", etc. are based on the orientation or positional relationship shown in the drawings, are merely for convenience of description and to simplify the description, and are not indicative or implying that the apparatus or elements being referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the present application.

According to a first aspect of the present application, there is provided a plug-in transdermal drug delivery device comprising:

a tray assembly 10, the tray assembly 10 comprising:

the disc body 11 is provided with a central cavity 112 and an annular negative pressure annular cavity 111, wherein the negative pressure annular cavity 111 is provided with an air guide elbow joint 114;

a tray cover 12 connected to the tray 11 and disposed above the central cavity 112;

an electronic component comprising an electric heating element 13, said electric heating element 13 being located on said tray 11 and above said central cavity 112 to indirectly heat said central cavity 112;

a first seal member connected to the tray 11, the first seal member sealing the electronic component from water;

a first electrical plug 17, which is connected with the first sealing element in a sealing way, wherein the top of the first electrical plug 17 extends out of the first sealing element, and the bottom of the first electrical plug 17 is electrically connected with the electronic element;

a tray cover assembly 20 disposed on the tray body assembly 10, the tray cover assembly 20 comprising:

a tray cover 21, configured to cover the first sealing member and be connected with the first sealing member in a sealing manner; the side surface of the tray cover 21 is provided with an air guide pipe joint 211 and an air guide elbow joint 213, the air guide pipe joint 211 is used for being connected with an external air extraction device through an air guide pipe 221, the air guide pipe joint 211 is used for forming ventilation connection with the air guide elbow joint 213, and the air guide elbow joint 213 is used for forming ventilation connection with the air guide elbow joint 114;

and a second electrical plug 24 connected to the tray cover 21 and disposed inside the tray cover 21, the second electrical plug 24 being electrically connected to an external power source. Specifically, the second electrical plug 24 is electrically connected to the conductive conduit 221 through an internal wire, and the conductive conduit 221 is electrically connected to an external power source.

Wherein the first electrical plug 17 is in frictional connection with the second electrical plug 24, the tray body assembly 10 and the tray cover assembly 20 are combined with each other to prevent the tray cover assembly 20 from falling off the tray body assembly 10 when the first electrical plug 17 is plugged with the second electrical plug 24, and the tray body assembly 10 and the tray cover assembly 20 are separated from each other to sterilize the tray body assembly 10 when the first electrical plug 17 is detached from the second electrical plug 24.

In this application, through first electric plug-in 17 with the grafting combination and the dismantlement separation of second electric plug-in 24, disk body subassembly 10 and disk lid subassembly 20 are detachable connection, can disinfect alone with the disk body subassembly 10 of skin contact after the treatment is over, for example boils disinfect with hot water, has guaranteed the biosafety when using next time.

In this application, the first sealing member in the disk assembly 10 seals the electronic component so as to be waterproof, ensures that the electronic component is always in an isolated state with disinfection liquids such as water and alcohol when the electronic component is boiled and disinfected in hot water, and prevents the electronic component from being stained with water and being damaged by short-circuit when the electronic component is used next time. In the embodiment shown in fig. 2, 3, 5, 7, 8, 10, 12 and 13, the first seal is a split structure comprising a tray cover 12 and a first socket 16; in other embodiments, the first seal member may also be an integral structure in which the tray cover 12 and the first socket 16 are fixedly connected together. The first socket 16 is tightly connected with the tray cover 12, and is fixedly connected with a first electric plug 17 and is electrically connected with the electric heating element 13 and the temperature sensing element 14 through an inner lead 15.

In some embodiments, a central protrusion 113 protruding downward is formed in the central cavity 112, and the drug pad can be sleeved on the central protrusion 113 for positioning. The central cavity 112 is connected to the negative pressure annular cavity 111 by an annular groove opening upwards to provide skin-compliant stretching and bending. In fig. 2, the electric heating element 13 is located between the tray 11 and the tray cover 12, the temperature sensing element 14 connected to the electric heating element 13 is located in the central boss 113, so that the bottom surface of the central boss 113 can provide support and fixation for the temperature sensing element 14. The temperature sensing element 14 can detect the temperature of the electric heating element 13, thereby indirectly detecting the temperature in the central cavity 112, on one hand, the release speed of the medicine molecules in the medicine pad can be controlled, and on the other hand, the temperature of the skin can be controlled, so as to prevent skin scalding or control the local blood circulation speed of the skin and further control the permeability of the skin.

In some embodiments, the second socket 23 is detachably connected to a support 214 formed inside the tray cover 21, so that the second socket 23 is mounted to the tray cover 21. For example, in fig. 3, the first electrical plug 242 is inserted into the corresponding mounting hole of the second socket 23, and then the first electrical plug 242 is electrically connected to the conductive wire of the conductive pipe 222 by the conductive wire, and then the second socket 23 is mounted on the support 214.

In the embodiment shown in fig. 2 and 3, the first electrical plug 17 is a first electrical plug barrel 172, and the second electrical plug 24 is a first electrical plug 242, so that the first electrical plug 242 is inserted into the first electrical plug barrel 172 when the opposite holes are observed from top to bottom; the tray assembly 10 and the tray cover assembly 20 are coupled to each other when the first electric plug 242 is inserted into the first electric plug housing 172, and the tray assembly 10 and the tray cover assembly 20 are separated from each other when the first electric plug 242 is separated from the first electric plug housing 172.

In the embodiment of fig. 7 and 8, the first electrical insert 17 is a second electrical insert 171 and the second electrical insert 24 is a second electrical insert 241 to facilitate cleaning of residual liquid from the second electrical insert 171 after sterilization of the tray assembly 10; the tray assembly 10 and the tray cover assembly 20 are coupled to each other when the second electric plunger 171 is inserted into the second electric cartridge 241, and the tray assembly 10 and the tray cover assembly 20 are separated from each other when the second electric plunger 171 is separated from the second electric cartridge 241.

The present application provides three ways of sealing connection of the tray cover 12 to the first socket 16:

in the embodiment shown in fig. 2 and 3, the sealing connection is performed by planar bonding: the tray cover 12 is formed with an annular groove having an opening toward the center of the tray cover 12, and the first socket 16 is inserted into the annular groove and is connected with the annular groove by bonding to seal the tray cover 12 with the first socket 16. In other embodiments, it is also possible to: the first socket 16 forms an annular groove with an opening facing the edge of the tray cover 12, and the tray cover 12 is inserted into the annular groove and is connected with the annular groove by bonding so as to seal the tray cover 12 with the first socket 16. By providing an annular groove, the tray cover 12 forms a mechanical limit to the first socket 16, which can effectively prevent the first socket 16 from shaking and loosening relative to the tray cover 12, the sealing durability of the tray cover 12 and the first socket 16 is increased. In the embodiment shown in fig. 2 and 3, the inner edge 121 of the cover is configured to cooperate with the outer edge 161 of the first socket.

In the embodiment of fig. 7 and 8, the sealing connection is performed by means of groove bonding: the tray cover 12 is formed with a tray cover ring groove 122 with an opening facing upwards, and the first socket 16 is formed with a rim extending downwards, and the rim is inserted into the tray cover ring groove 122 and is connected by adhesion so as to seal the tray cover 12 with the first socket 16. For example, the bonding mode may be to inject glue solution into the disc body cover ring groove 122, the glue solution is self-leveling in the disc body cover ring groove 122 due to gravity, and the glue solution is tightly bonded with the disc body cover ring groove 122 into a whole after being inserted along the edge, so that the waterproof effect and the sealing effect are better.

In the embodiment of fig. 12 and 13, the sealing connection is made in a flange-like manner: the tray cover 12 is formed with a tray cover flange 123, the first socket 16 is formed with a first socket flange, and the fastener 124C is sleeved on the tray cover flange 123 and the first socket flange to seal the tray cover 12 and the first socket 16. In the embodiment of fig. 12 and 13, the fastener 124C is a nut. In some embodiments, a plurality of pairs of the tray cover flange 123 and the first socket flange may be disposed in the circumferential direction of the tray cover 12 and the first socket 16 according to the requirement of the sealing performance, and a corresponding number of fasteners 124C may be disposed to enhance the sealing performance between the tray cover 12 and the first socket 16. The tray cover flange 123, the first socket flange, and the fastener 124C cooperate with each other to increase the sealing reliability of the tray cover 12 and the first socket 16.

The present application provides two ways in which the air guide conduit fitting 211 forms an air-vented connection with the air guide elbow fitting 213:

the air guide pipe joint 211 and the air guide elbow joint 213 form an air connection, which may be: an air pipe is connected between the air guide pipe joint 211 and the air guide elbow joint 213 to form an air ventilation connection. In this way, the air pipe connects the air source, the air guide pipe joint 211, the air guide elbow joint 213, the air guide elbow joint 114 and the negative pressure annular cavity 111 together in sequence, and an independent closed negative pressure system is formed in use, which is basically not influenced by other components, such as the sealing effect of the tray cover 12 and the first socket 16, and has a simple and reliable structure.

The air guide pipe joint 211 and the air guide elbow joint 213 form an air connection, which may be: in the embodiments of fig. 2, 3, 7, 8, 12 and 13, the tray cover 21 is used to cover the first sealing member and is in sealing connection with the first sealing member so as to form a ventilation connection between the air guide pipe joint 211 and the air guide elbow joint 213; when the air guide pipe joint 211 and the air guide elbow joint 213 form an air connection, a negative pressure space is formed inside the tray cover 21, so that the sealing force between the tray cover 21 and the first sealing member is increased to prevent the tray cover 21 from falling off from the first sealing member. Specifically, in the embodiment shown in the drawings, the first sealing member is a split structure including a tray cover 12 and a first socket 16, and the tray cover 21 covers the first socket 16 and is connected with the first socket 16 in a sealing manner to form a ventilation connection between the air guide pipe joint 211 and the air guide elbow joint 213.

The engagement of the tray cover 21 with the first socket 16 is achieved by friction between the electrical pins 242, 171 and the electrical sockets 241, 172. During actual operation, the friction force should be sufficient to keep the cover assembly 20 and the tray assembly 10 as a single unit. During application of the tray assembly 10 to the skin, the operator holds the tray cover 21 in his hands and moves it in the air, and the friction force should be greater than the weight of the tray assembly 10 to prevent the tray assembly 10 from falling off the tray cover assembly 20 and falling to the ground. When the disc assembly 10 is applied to the skin, the disc assembly 10 is adsorbed on the skin by the negative pressure formed by the annular negative pressure ring cavity 111, and at this time, if the body position of the human body is prone, the insertion type transdermal drug delivery device is applied to the back of the human body, the gravity of the disc cover assembly 20 and the catheter 22 mounted thereon is pressurized on the disc assembly 10, and the combination of the disc cover assembly 20 and the disc assembly 10 is stable. However, if the body position of the person is sitting, the weight of the cap assembly 20 including the catheter 22 mounted thereon becomes a pulling separation force, increasing the risk of the cap assembly 20 falling off the disc assembly 10, and if the catheter 22 mounted on the cap assembly 20 swings in the air during treatment when the person shakes, this pulling separation force is increased, and if the friction between the electrical plungers 242, 171 and the electrical cartridges 241, 172 is small, the cap assembly 20 is at risk of falling off. However, excessive friction may result in a significant amount of force being required to separate the cap assembly 20 from the tray assembly 10 after the end of the treatment, which may increase the difficulty of operation.

In the embodiment in which the negative pressure space is formed inside the tray cover 21, the negative pressure generated during the treatment process is utilized to reduce the friction force between the electric plungers 242, 171 and the electric plungers 241, 172, so that the friction force is only ensured to be greater than the gravity of the tray assembly 10 when the tray cover 21 is pinched by hands to move in the air, and the tray assembly 10 cannot fall off. During the treatment, a negative pressure space is formed inside the tray cover body 21, and the formed negative pressure makes the tray cover body 21 including the tray cover assembly 20 integrated with the tray cover body to be adsorbed on the first plugging seat 16, so that the sealing force between the tray cover body 21 and the first plugging seat 16 is increased, the gravity of the tray cover assembly 20 and the guide tube 22 thereon and the pulling force formed when the guide tube 22 swings are reduced or offset, and the risk of falling off of the tray cover assembly 20 is avoided during the whole treatment. Thus, the self-tightening effect of the plug-in type percutaneous administration device is achieved, the continuous electric connection is maintained, and the reliability of the plug-in type percutaneous administration device is improved.

In order to realize that the inside negative pressure space that forms of tray lid 21, this application provides two kinds of tray lids 21 and the sealed mode of first bayonet socket 16 grafting:

as shown in fig. 7, 8 and 10, the outer surface of the first socket 16 is formed with a groove with an outward opening, a sealing ring 124A is disposed in the groove, and the disc cover 21 is in sealing connection with the first socket 16 by abutting against the sealing ring 124A. The seal ring 124A used in this way is shown in fig. 11, and has a simple structure and low production cost.

As shown in fig. 12 and 13, the first socket 16 is formed with a first socket annular groove 162 with an upward opening, a U-shaped sealing ring 124B with an upward opening is disposed in the first socket annular groove 162, and the disc cover 21 is inserted into the U-shaped sealing ring 124B to be in sealing connection with the first socket 16. As shown in FIG. 11, the U-shaped sealing rings 124B used in the method seal the two sides of the tray cover 21, and the U-shaped sealing rings 124B on the two sides and the bottom of the tray cover 21 can elastically deform, so that a good sealing effect between the tray cover 21 and the first plug seat 16 is realized. As shown in fig. 12 and 13, protrusions facing the disc cover 21 are provided on both sides of the first socket annular groove 162, and the top end of the U-shaped ring seal abuts against the protrusions, so that the U-shaped ring seal can be prevented from being carried out of the first socket annular groove 162 when the disc cover 21 is pulled out, and the damage rate of the plug-in type transdermal drug delivery device is reduced.

The tray assembly 10 includes a first electrical insert 17 and the tray cover assembly 20 includes a second electrical insert 24. The first electrical plug 17 is a first electrical plug barrel 172, and the second electrical plug 24 is a first electrical plug rod 242, so that the first electrical plug rod 242 is inserted into the first electrical plug barrel 172 by observing the opposite holes from top to bottom; the bottom end of the first electric plug 172 is closed to prevent the liquid from contacting with the electronic component and shorting out, and the first electric plug 242 is provided with an air exhaust channel 242A to prevent the first electric plug 242 from compressing air in the first electric plug 172, which makes it difficult for the first electric plug 242 to be inserted into the first electric plug 172. Fig. 6 shows a form of a first electric plunger 242 with a vent passage 242A open thereon in the form of a side slot. Fig. 4 shows a first electrical plug 242, fig. 5 shows a first electrical socket 172, in the embodiment shown in fig. 2, 3, the first electrical plug 172, the first electrical plug 242 is shown, and fig. 2, 3 show the shape change of the first electrical plug 242 with the vent passage 242A opened in different cross sections.

In the embodiment shown in fig. 7 and 8, the first electrical plug 17 is a second electrical plug 171, and the second electrical plug 24 is a second electrical plug 241, so as to clean residual liquid on the second electrical plug 171 after the tray assembly 10 is steamed and sterilized; the top end of the second electric plug 241 is provided with a through hole, so as to prevent the second electric plug 171 from being difficult to be inserted into the second electric plug 241 due to the compression of the second electric plug 171 to the air in the second electric plug 241. The second electric plug 241 is shown in fig. 9, the second electric plug 171 is shown in fig. 10, and the support 214 is provided with a gas inlet and a gas outlet, which communicate with the space formed by the support 214 and the second plug seat 23 and the inside of the tray cover 21, so as to prevent the second electric plug 171 from being difficult to be inserted into the second electric plug 241 due to the compression of the air in the space formed by the support 214 and the second plug seat 23.

It should be noted that, in the case of no conflict, the embodiments and technical features of the embodiments in the present application may be combined with each other, and the present application schematically provides some combined embodiments to illustrate possible combinations:

example 1:

fig. 1 is a schematic top view of a plug-in transdermal drug delivery device according to some embodiments of the present application, including a tray assembly 10, a tray cover assembly 20, a catheter 22, and an air guide elbow 30. One end of the air guide elbow 30 is communicated with the negative pressure annular cavity 111 through an air guide elbow joint 114, and the other end is connected with an air guide elbow joint 213 on the tray cover 21. The duct 22 includes an air duct 221 and a conductive duct 222. The side surface of the tray cover body 21 is provided with an air guide pipe joint 211, the air guide pipe joint 211 is connected with an air guide pipe 221, the adjacent part is also provided with a conductive pipe joint 212, and the second electric plug 24 is connected with a conductive pipe 222 through an inner lead 15; the side of the tray cover 21 is also provided with an air guide elbow joint 213, the air guide elbow joint 213 is perpendicular to the side of the tray cover 21, one end of the air guide elbow joint 213, which is positioned at the outer side of the tray cover 21, is communicated with the air guide elbow 30, and one end of the air guide elbow joint 211, which is positioned at the inner side of the tray cover 21, is communicated with the air guide pipe joint 211. Fig. 1 is a schematic top view of a plug-in transdermal drug delivery device according to some embodiments of the present application, fig. 2 is a cross-sectional view A-A in fig. 1, fig. 3 is a cross-sectional view B-B in fig. 1, fig. 4 is a schematic view of a disc cover assembly 20 according to some embodiments of the present application, fig. 5 is a schematic view of a disc assembly 10 according to some embodiments of the present application, and fig. 6 is an isometric schematic view of an electrical plug according to some embodiments of the present application. The embodiment of the combination is a combination of the structures shown in fig. 1-6, and has technical effects brought by the corresponding structures.

Example 2: fig. 1 is a schematic top view of a plug-in type transdermal drug delivery device according to some embodiments of the present application, fig. 7 is a cross-sectional view A-A in fig. 1, fig. 8 is a cross-sectional view B-B in fig. 1, fig. 9 is a schematic view of a disc cover assembly 20 according to some embodiments of the present application, fig. 10 is a schematic view of a disc body assembly 10 according to some embodiments of the present application, and fig. 11 is a schematic view of a seal ring 124A according to some embodiments of the present application. The present combined embodiment is a combination of the structures shown in figures 1 and 7-11, has the technical effect brought by the corresponding structure.

Example 3: fig. 1 is a schematic top view of a plug-type transdermal drug delivery device according to some embodiments of the present application, fig. 12 is a cross-sectional view A-A of fig. 1 according to some embodiments of the present application, fig. 13 is a cross-sectional view B-B of fig. 1 according to some embodiments of the present application, and fig. 14 is a schematic view of a U-shaped sealing ring 124B according to some embodiments of the present application. The embodiment of the combination is a combination of the structures shown in fig. 1 and 12-14, and has technical effects brought by the corresponding structures.

Based on the same conception, embodiments of the second aspect of the present application also provide a method of using a plug-in transdermal drug delivery device, the using method comprises the following steps:

s101, sleeving the medicine pad on the central convex column 113 in the central cavity 112.

S102, combining the disc cover assembly 20 with the disc body assembly 10: the first electrical connector 17 is connected to the second electrical connector 24.

S103, air is pumped through the air guide pipe joint 211 of the tray cover assembly 20, and negative pressure is formed in the tray cover body 21 and a negative pressure annular cavity arranged on the tray body 11.

S104, the negative pressure ring cavity 111 is adsorbed on the skin.

S105, the central cavity 112 is indirectly heated by the electric heating element 13, so that the temperature of the central cavity 112 is promoted to rise to promote the drug molecules of the drug pad to pass through the skin.

S106, the temperature sensing element 14 is connected with the electric heating element 13 to detect the temperature of the electric heating element 13.

And S107, after the treatment is finished, separating the disc cover assembly 20 from the disc body assembly 10, and steaming and sterilizing the disc body assembly 10 for the next use.

In this application, through the grafting combination and the dismantlement separation of first electric plug-in components 17 and second electric plug-in components 24, disk body subassembly 10 and disk lid subassembly 20 are detachable connection, can disinfect with the disk body subassembly 10 of skin contact alone after the treatment is over, for example boils disinfection in hot water, has guaranteed the biosafety when using next time.

Thus, embodiments of the present application have been described in detail with reference to the accompanying drawings. It should be noted that, in the drawings or the text of the specification, implementations not shown or described are all forms known to those of ordinary skill in the art, and not described in detail.

The foregoing embodiments have been provided for the purpose of illustrating the general principles of the present application, and are not meant to limit the scope of the utility model, but to limit the scope of the utility model.

Claims

1. A plug-in transdermal drug delivery device, comprising:

a tray assembly, the tray assembly comprising:

2. The plug-in transdermal drug delivery device according to claim 1, wherein,

the first electric plug is a first electric plug cylinder, and the second electric plug is a first electric plug rod, so that the first electric plug rod is inserted into the first electric plug cylinder by observing the opposite holes from top to bottom; when the first electric plug rod is inserted into the first electric plug cylinder, the disc body assembly and the disc cover assembly are combined with each other, and when the first electric plug rod is separated from the first electric plug cylinder, the disc body assembly and the disc cover assembly are separated from each other; ###

3. The plug-in transdermal drug delivery device according to claim 1, wherein,

the first electric plug-in unit is an electric plug-in rod, and the second electric plug-in unit is an electric plug-in cylinder, so that residual liquid on the electric plug-in rod can be cleaned conveniently after the tray body assembly is steamed and disinfected;

4. The plug-in transdermal drug delivery device according to claim 1, wherein the first seal comprises a tray cover, a first plug seat, wherein,

5. The plug-in transdermal drug delivery device according to claim 1, wherein the first seal comprises a tray cover, a first plug seat, wherein,

6. The plug-in transdermal drug delivery device according to claim 1, wherein the first seal comprises a tray cover, a first plug seat, wherein,

7. The plug-in transdermal drug delivery device of claim 1, wherein the air guide conduit connector and the air guide elbow connector form a vented connection, comprising:

an air pipe is connected between the air guide pipe joint and the air guide elbow joint to form ventilation connection; or (b)

8. The plug-in transdermal drug delivery device according to claim 1, wherein the first seal comprises a tray cover, a first plug seat, wherein,

9. The plug-in transdermal drug delivery device according to claim 1, wherein,

the first electric plug is a first electric plug cylinder, and the second electric plug is a first electric plug rod, so that the first electric plug rod is inserted into the first electric plug cylinder by observing the opposite holes from top to bottom; the bottom end of the first electric plug cylinder is sealed to prevent liquid from being in contact with the electronic element and short-circuited, and an exhaust channel is formed in the first electric plug rod to prevent the first electric plug rod from compressing air in the first electric plug cylinder, so that the first electric plug rod is difficult to insert into the first electric plug cylinder.

10. The plug-in transdermal drug delivery device according to claim 1, wherein,

the first electric plug-in unit is a second electric plug-in rod, the second electric plug-in unit is a second electric plug-in cylinder, so as to clean residual liquid on the second electric plunger after the tray body assembly is boiled and disinfected; the top end of the second electric plug cylinder is provided with a through hole so as to prevent the second electric plug rod from compressing air in the second electric plug cylinder to cause that the second electric plug rod is difficult to insert into the second electric plug cylinder.