CN220315880U - Sealing bottle for lentivirus storage - Google Patents
Sealing bottle for lentivirus storage Download PDFInfo
- Publication number
- CN220315880U CN220315880U CN202322015505.2U CN202322015505U CN220315880U CN 220315880 U CN220315880 U CN 220315880U CN 202322015505 U CN202322015505 U CN 202322015505U CN 220315880 U CN220315880 U CN 220315880U
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- China
- Prior art keywords
- sealing
- plate
- lentivirus
- sealed bottle
- embedded groove
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- 238000007789 sealing Methods 0.000 title claims abstract description 104
- 241000713666 Lentivirus Species 0.000 title claims abstract description 27
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 44
- 239000011521 glass Substances 0.000 claims abstract description 10
- 230000000007 visual effect Effects 0.000 claims abstract description 9
- 229920001971 elastomer Polymers 0.000 claims description 9
- 230000000903 blocking effect Effects 0.000 claims 1
- 238000004321 preservation Methods 0.000 abstract 1
- 239000006260 foam Substances 0.000 description 6
- 230000000694 effects Effects 0.000 description 3
- 239000013598 vector Substances 0.000 description 3
- 206010011409 Cross infection Diseases 0.000 description 2
- 241000713772 Human immunodeficiency virus 1 Species 0.000 description 2
- 206010029803 Nosocomial infection Diseases 0.000 description 2
- 229920001821 foam rubber Polymers 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 239000012780 transparent material Substances 0.000 description 2
- 208000031886 HIV Infections Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 101150010487 are gene Proteins 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 238000001415 gene therapy Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000001177 retroviral effect Effects 0.000 description 1
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- Closures For Containers (AREA)
Abstract
The utility model discloses a sealing bottle for lentivirus storage, which comprises a sealing bottle body and a sealing cover, wherein an external thread part is fixedly arranged at the upper end of the sealing bottle body, an internal thread part is fixedly arranged at the lower end of the sealing cover, the external thread part and the internal thread part are fixedly connected through threads, visual glass is arranged on the left side and the right side of the sealing bottle body, a first embedded groove and a second embedded groove are respectively arranged on the left side and the right side of the sealing cover, a first sealing plate and a second sealing plate are respectively embedded in the first embedded groove and the second embedded groove, a bottom plate is fixedly arranged on the front side and the rear side of the sealing bottle body, a transverse plate is clamped on the bottom plate, a plurality of placing openings are formed in the transverse plate, and reagent tubes are arranged in the placing openings; the utility model is convenient for observation, convenient for light-proof preservation and strong in sealing property.
Description
Technical Field
The utility model relates to the technical field of sealed bottles, in particular to a sealed bottle for storing slow viruses.
Background
Lentiviral (Lentivirus) vectors are gene therapy vectors developed based on HIV-1 (human immunodeficiency virus type I), which distinguish between retroviral vectors in general and which have infectivity in both dividing and non-dividing cells. Lentiviral reagents are generally stored in a kit, but the existing kit has the main effects of being limited to storage and poor in sealing performance, and the lentiviral reagents are not convenient to observe lentivirus when being contained in the kit.
The utility model of the prior art with the publication number of CN211255916U is a sealing bottle for lentivirus packaging, and the whole body of the sealing bottle body is of an integrated structure, so that the sealing bottle body has good sealing performance, and is made of transparent materials, thereby being more convenient for observing lentivirus; however, since the storage of lentivirus needs to satisfy the sealed condition, still needs to keep away from light, if exposing in the stronger environment of light for a long time, the reagent is inefficacy easily, causes the testing result error great, detects the failure even, and the observation of lentivirus needs to observe the record many times in certain time, and the prior art adopts full transparent material although being convenient for the observation of lentivirus, but need to shift out the sealed bottle repeatedly and shift back the light-proof department again when observing, complex operation and very inconvenient, therefore this application provides a sealed bottle for lentivirus storage.
Disclosure of Invention
The utility model aims to provide a sealed bottle for lentivirus storage, which is convenient to observe, convenient to preserve in a dark place and strong in sealing performance.
In order to achieve the above purpose, the present utility model provides the following technical solutions:
the utility model provides a be used for lentivirus to store with sealed bottle, includes sealed bottle body and closing cap, sealed bottle body upper end is fixed and is equipped with external screw thread portion, the closing cap lower extreme is fixed and is equipped with internal screw thread portion, external screw thread portion with internal screw thread portion passes through screw thread fixed connection, sealed bottle body left and right sides all is equipped with visual glass, the closing cap left and right sides is equipped with interior caulking groove one and interior caulking groove two respectively, interior caulking groove one with inlay groove two respectively the embedding be equipped with closing plate one and closing plate two, closing plate one with closing plate two be close to interior caulking groove one with one side lower terminal surface of interior caulking groove two inboard is all fixed and is equipped with the semi-ring buckle, interior caulking groove one with interior caulking groove two port is all fixed and is equipped with the diaphragm, the diaphragm upper end respectively with the correspondence closing plate two lower terminal surface offsets, both sides all are fixed and are equipped with the bottom plate in the sealed bottle body, the card is equipped with the diaphragm on the bottom plate, be equipped with a plurality of placing ports on the diaphragm, all be equipped with reagent in the placing port.
By adopting the technical scheme, the utility model has the following advantages:
the arrangement of the internal thread part and the external thread part ensures that the sealing cover and the sealing bottle body can be fixedly connected through threads to play a role in sealing the sealing bottle body; the visual glass is convenient for staff to observe and study the lentivirus reagent; according to the utility model, the first sealing plate and the second sealing plate are arranged, so that when a worker does not observe the lentiviral reagent and needs to keep the lentiviral reagent in a dark place, the semi-ring buckle plate is buckled on the transverse column only by pulling out the first sealing plate and the second sealing plate, and when the worker needs to observe, the first sealing plate and the second sealing plate are pushed back into the first embedded groove and the second embedded groove, and the sealed bottle body does not need to be repeatedly moved out of the dark place, so that the sealed bottle is more convenient to use.
Furthermore, the first sealing plate and the second sealing plate are fixedly provided with pull ropes at one ends far away from the semi-ring buckle plates.
By adopting the technical scheme, the utility model has the following advantages:
the stay cord of the utility model plays a role in facilitating the pulling out of the first sealing plate and the second sealing plate.
Further, screw holes I are formed in the first sealing plate and the second sealing plate, and screw holes II are formed in the left side and the right side of the sealing cover, corresponding to the screw holes I.
By adopting the technical scheme, the utility model has the following advantages:
according to the utility model, the first threaded hole and the second threaded hole are arranged, so that when the lentivirus reagent needs to be stored, the first sealing plate and the second sealing plate can be fixed by penetrating the first threaded hole and the second threaded hole through bolts, and the lentivirus reagent can be stored in a dark place.
Further, the lower end of the sealing bottle body is sleeved with a rubber sleeve, and two ends of the rubber sleeve are respectively provided with an inner groove.
By adopting the technical scheme, the utility model has the following advantages:
the rubber sleeve provided by the utility model has the effect of increasing the friction force between the sealing bottle body and the tabletop, and can effectively prevent the sealing bottle body from slipping to cause damage, and the inner groove is arranged so that when the sealing plate I and the sealing plate II are pulled out, the pull rope can be clamped at the inner groove.
Furthermore, the internal fixation of placing the mouth is equipped with annular cutting ferrule, reagent pipe upper end is equipped with the arch around fixed, protruding lower extreme with reagent pipe outside all with annular cutting ferrule offsets, the inboard embedding of reagent pipe upper end is equipped with the shutoff.
By adopting the technical scheme, the utility model has the following advantages:
the reagent tubes can be clamped on the placing opening by the aid of the bulges, the annular clamping sleeve is arranged to fix the reagent tubes, and each reagent tube can be sealed independently by means of plugging, so that cross infection is effectively prevented.
Further, a handle is fixedly arranged at the upper end of the sealing cover, a sealing layer is fixedly arranged at the lower end of the sealing cover, and the lower end face of the sealing layer abuts against the upper end face of the sealing plug.
By adopting the technical scheme, the utility model has the following advantages:
the arrangement of the sealing layer further enhances the tightness of the sealing bottle body and the reagent tube.
Further, both sides of the upper end of the bottom plate are respectively provided with a rotating plate through rotating nails, the upper ends of the rotating plates are respectively fixedly provided with an L-shaped plate, and the lower ends of one side of the L-shaped plates are propped against the upper end faces of the transverse plates.
By adopting the technical scheme, the utility model has the following advantages:
the L-shaped plate is arranged, so that when the L-shaped plate is screwed out to prop against the transverse plate, the transverse plate can be fixed, and workers are prevented from taking out the transverse plate when the reagent tube is pulled out.
Further, the upper end of the bottom plate is provided with clamping grooves, a foam-rubber cushion is arranged in the clamping grooves, clamping blocks are fixedly arranged at the positions, corresponding to the clamping grooves, of the lower end of the transverse plate, and the clamping blocks are clamped in the foam-rubber cushion.
By adopting the technical scheme, the utility model has the following advantages:
the clamping groove, the clamping block and the foam cushion are arranged, so that the transverse plate can be rapidly positioned and fixed on the bottom plate, the foam cushion plays a role of extruding the clamping block, the clamping block can be more firmly fixed in the clamping groove, and finally the transverse plate cannot be randomly moved.
Drawings
The utility model will be further described with reference to the drawings and examples.
FIG. 1 is a schematic elevational cross-sectional view of the present utility model;
FIG. 2 is a schematic view of the cross-sectional structure of the front (drawn out sealing plate) of the present utility model;
FIG. 3 is a schematic view of a left-hand cross-sectional structure of the present utility model;
FIG. 4 is a schematic elevational cross-sectional view of the closure of the present utility model;
FIG. 5 is an enlarged schematic view of the structure of FIG. 2A according to the present utility model;
FIG. 6 is an enlarged schematic view of the structure of FIG. 2B according to the present utility model;
FIG. 7 is a schematic top view cross-sectional structure of the present utility model;
fig. 8 is an enlarged view of the structure of fig. 3 at C according to the present utility model.
Reference numerals: 1. sealing the bottle body; 101. visual glass; 102. an external thread portion; 2. a reagent tube; 201. a protrusion; 202. plugging; 3. a cover; 301. the first embedded groove is formed; 302. a second embedded groove; 4. a rubber sleeve; 401. an inner groove; 5. a bottom plate; 501. a clamping groove; 502. a sponge cushion; 6. a cross plate; 601. a placement port; 602. a clamping block; 7. a rotating plate; 701. rotating nails; 702. an L-shaped plate; 8. a handle; 9. a sealing layer; 10. a second sealing plate; 11. a first sealing plate; 12. an annular cutting sleeve; 13. a half-ring buckle plate; 14. a cross column; 15. a pull rope; 16. a first threaded hole; 17. and a threaded hole II.
Detailed Description
As shown in fig. 1 to 3, in the specific embodiment, a sealed bottle for lentivirus storage comprises a sealed bottle body 1 and a sealing cap 3, wherein an external thread 102 is fixedly arranged at the upper end of the sealed bottle body 1, an internal thread 14 is fixedly arranged at the lower end of the sealing cap 3, the external thread 102 and the internal thread are fixedly connected through threads, visible glass 101 is respectively arranged at the left side and the right side of the sealed bottle body 1, an embedded groove 301 and an embedded groove 302 are respectively arranged at the left side and the right side of the sealing cap 3, a sealing plate 11 and a sealing plate 10 are respectively embedded in the embedded groove 301 and the embedded groove 302, a semi-ring buckle 13 is fixedly arranged at the lower end face of one side, close to the inner side of the embedded groove 301 and the embedded groove 302, of the sealing plate 11 and the embedded groove 302, a cross post 14 is fixedly arranged at the upper end of the cross post and is respectively abutted against the lower end faces of the corresponding sealing plate 11 and the embedded groove 10, a bottom plate 5 is fixedly arranged at the front side and the rear side of the sealed bottle body 1, a cross plate 6 is arranged on the bottom plate 5, a plurality of placing ports 601 are respectively arranged on the cross plate 6, and a plurality of placing ports 601 are respectively arranged on the bottom plate 6.
Through the arrangement, the sealing cap 3 and the sealing bottle body 1 can be fixedly connected through the threads by arranging the internal thread part and the external thread part 102, so that the sealing bottle body 1 is sealed; the visual glass 101 is arranged, so that a worker can observe and research lentiviral reagents conveniently; the arrangement of the first sealing plate 11 and the second sealing plate 10 ensures that when a worker does not observe a lentiviral reagent and needs to keep the lentiviral reagent away from light, the semi-ring buckle plate 13 is buckled on the transverse column 14 only by pulling out the first sealing plate 11 and the second sealing plate 10, and when the worker needs to observe, the first sealing plate 11 and the second sealing plate 10 are pushed back into the first embedded groove 301 and the second embedded groove 302, so that the sealed bottle body 1 does not need to be repeatedly moved out of the light-proof position, and the use is more convenient.
As shown in fig. 4 to 6, a pull rope 15 is fixedly arranged at one end of each of the first sealing plate 11 and the second sealing plate 10, which is far away from the semi-ring buckle plate 13; screw holes I16 are formed in the first sealing plate 11 and the second sealing plate 10, and screw holes II 17 are formed in the left side and the right side of the sealing cover 3 and correspond to the screw holes I16; the lower end of the sealing bottle body 1 is sleeved with a rubber sleeve 4, and both ends of the rubber sleeve 4 are provided with inner grooves 401.
Through the arrangement, the stay cord 15 plays a role in facilitating the pulling out of the first sealing plate 11 and the second sealing plate 10; according to the utility model, the first threaded hole 16 and the second threaded hole 17 are arranged, so that when the lentivirus reagent needs to be stored, the first sealing plate 11 and the second sealing plate 10 can be fixed by penetrating the first threaded hole 16 and the second threaded hole 17 through bolts, and the lentivirus reagent can be stored in a dark place; the rubber sleeve 4 has the function of increasing friction force between the sealed bottle body 1 and the tabletop, and can effectively prevent the sealed bottle body 1 from slipping to cause damage, and the inner groove 401 is arranged so that when the first sealing plate 11 and the second sealing plate 10 are pulled out, the pull rope 15 can be clamped at the inner groove 401.
As shown in fig. 3, 7 and 8, an annular clamping sleeve 12 is fixedly arranged in a placement opening 601, a bulge 201 is fixedly arranged on the upper end of a reagent tube 2 in a surrounding manner, the lower end of the bulge 201 and the outer side of the reagent tube 2 are propped against the annular clamping sleeve 12, and a plug 202 is embedded into the inner side of the upper end of the reagent tube 2; the upper end of the sealing cover 3 is fixedly provided with a handle 8, the lower end of the sealing cover 3 is fixedly provided with a sealing layer 9, and the lower end face of the sealing layer 9 is propped against the upper end face of the plug 202; the two sides of the upper end of the bottom plate 5 are provided with rotating plates 7 through rotating nails 701, the upper ends of the rotating plates 7 are fixedly provided with L-shaped plates 702, and the lower ends of one sides of the L-shaped plates 702 are propped against the upper end surfaces of the transverse plates 6; the upper end of the bottom plate 5 is provided with a clamping groove 501, a foam cushion 502 is arranged in the clamping groove 501, a clamping block 602 is fixedly arranged at the lower end of the transverse plate 6 corresponding to the clamping groove 501, and the clamping block 602 is clamped in the foam cushion 502.
Through the arrangement, the reagent tubes 2 can be clamped on the placing opening 601 by the arrangement of the protrusions 201, the annular clamping sleeve 12 plays a role in fixing the reagent tubes 2, and each reagent tube 2 can be independently sealed by the arrangement of the plugs 202, so that cross infection is effectively prevented; the sealing layer 9 further enhances the tightness of the sealed bottle body 1 and the reagent tube 2; the L-shaped plate 702 is arranged, so that when the L-shaped plate 702 is screwed out to prop against the transverse plate 6, the L-shaped plate 702 can play a role in fixing the transverse plate 6, and the transverse plate 6 is prevented from being taken out by staff when the reagent tube 2 is pulled out; the clamping groove 501, the clamping block 602 and the foam cushion 502 are arranged, so that the transverse plate 6 can be rapidly positioned and fixed on the bottom plate 5, the foam cushion 502 plays a role of extruding the clamping block 602, the clamping block 602 can be more firmly fixed in the clamping groove 501, and finally the transverse plate 6 cannot be randomly moved.
Working principle: during the use, put lentiviral reagent in reagent pipe 2 and seal through shutoff 202, place reagent pipe 2 in sealed bottle body 1 again, insert in annular cutting ferrule 12, make protruding 201 lower extreme offset with annular cutting ferrule 12, play the effect of fixed reagent pipe 2, rethread both sides L template 702 rotates to block and establish on diaphragm 6, when making take out reagent pipe 2, diaphragm 6 is difficult for removing, finally fix on sealed bottle body 1 through closing cap 3 spiral, sealing layer 9 further plays the sealed that extrusion shutoff 202 realized lentiviral reagent, after placing, need observe when need observe only push into indent and indent second 302 one respectively with closing plate first 11 and closing plate second 10, observe through visual glass 101, the time between the two observations, accessible stay cord 15 draws closing plate first 11 and closing plate second 10, until semi-ring buckle 13 detains on diaphragm 14, at this moment closing plate first 11 and closing plate second 10 can block visual glass 101, realize the photophobic save of lentiviral reagent, when observing and need store lentiviral reagent for a long time, need only pass first screw hole 16 and second screw hole 17 and two screw hole, make sealing plate 1 and sealing plate second 3 need not be connected repeatedly with the sealed bottle 1 and can be used to observe.
The above is only a preferred embodiment of the present utility model, and the protection scope of the present utility model is not limited to the above examples, and all technical solutions belonging to the concept of the present utility model belong to the protection scope of the present utility model. It should be noted that modifications and adaptations to the present utility model may occur to one skilled in the art without departing from the principles of the present utility model and are intended to be within the scope of the present utility model.
Claims (8)
1. The utility model provides a be used for lentivirus to store and use sealed bottle, includes sealed bottle body (1) and closing cap (3), sealed bottle body (1) upper end is fixed to be equipped with external screw thread portion (102), closing cap (3) lower extreme is fixed to be equipped with internal screw thread portion, external screw thread portion (102) with internal screw thread portion passes through screw thread fixed connection, its characterized in that, sealed bottle body (1) left and right sides all is equipped with visual glass (101), closing cap (3) left and right sides is equipped with embedded groove one (301) and embedded groove two (302) respectively, embedded groove one (301) with embedded groove two (302) are embedded respectively to be equipped with closing plate one (11) and closing plate two (10) in, closing plate one (11) with closing plate two (10) are close to embedded groove one (301) with semi-ring buckle (13) are all fixed to be equipped with in the terminal surface under one side of embedded groove two (302), embedded groove one (301) and embedded groove two (302) ports are all are fixed to be equipped with visual glass (101), be equipped with embedded groove one (14) respectively, be equipped with on the terminal surface (14) and one end face (6) of sealing plate (6) are equipped with respectively in front end face (6) of sealing plate one side, two (6) are equipped with respectively on the sealing plate one side (6) and two (6) are equipped with sealing plate top end respectively, the placing ports (601) are internally provided with reagent pipes (2).
2. The sealed bottle for lentivirus storage according to claim 1, wherein the first sealing plate (11) and the second sealing plate (10) are fixedly provided with pull ropes (15) at one ends far away from the semi-ring buckle plate (13).
3. The sealed bottle for lentivirus storage according to claim 2, wherein the first sealing plate (11) and the second sealing plate (10) are respectively provided with a first threaded hole (16), and the left and right sides of the sealing cover (3) are respectively provided with a second threaded hole (17) corresponding to the first threaded hole (16).
4. The sealed bottle for lentivirus storage according to claim 1, wherein the lower end of the sealed bottle body (1) is sleeved with a rubber sleeve (4), and both ends of the rubber sleeve (4) are provided with inner grooves (401).
5. The sealed bottle for lentivirus storage according to claim 1, wherein the placement opening (601) is internally and fixedly provided with an annular clamping sleeve (12), the upper end of the reagent tube (2) is fixedly provided with a protrusion (201) in a surrounding manner, the lower end of the protrusion (201) and the outer side of the reagent tube (2) are propped against the annular clamping sleeve (12), and the inner side of the upper end of the reagent tube (2) is embedded with a blocking piece (202).
6. The sealed bottle for lentivirus storage according to claim 5, wherein a handle (8) is fixedly arranged at the upper end of the sealing cover (3), a sealing layer (9) is fixedly arranged at the lower end of the sealing cover (3), and the lower end face of the sealing layer (9) is abutted against the upper end face of the plug (202).
7. The sealed bottle for lentivirus storage according to claim 1, wherein both sides of the upper end of the bottom plate (5) are provided with rotating plates (7) through rotating nails (701), the upper ends of the rotating plates (7) are fixedly provided with L-shaped plates (702), and the lower ends of one side of the L-shaped plates (702) are propped against the upper end faces of the transverse plates (6).
8. The sealed bottle for lentivirus storage according to claim 7, wherein the upper end of the bottom plate (5) is provided with clamping grooves (501), the clamping grooves (501) are internally provided with sponge pads (502), the lower ends of the transverse plates (6) are fixedly provided with clamping blocks (602) corresponding to the clamping grooves (501), and the clamping blocks (602) are clamped in the sponge pads (502).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322015505.2U CN220315880U (en) | 2023-07-29 | 2023-07-29 | Sealing bottle for lentivirus storage |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322015505.2U CN220315880U (en) | 2023-07-29 | 2023-07-29 | Sealing bottle for lentivirus storage |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220315880U true CN220315880U (en) | 2024-01-09 |
Family
ID=89422918
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322015505.2U Active CN220315880U (en) | 2023-07-29 | 2023-07-29 | Sealing bottle for lentivirus storage |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220315880U (en) |
-
2023
- 2023-07-29 CN CN202322015505.2U patent/CN220315880U/en active Active
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