CN220310171U - Raw material stirring device for cefuroxime axetil production for pharmaceutical engineering - Google Patents
Raw material stirring device for cefuroxime axetil production for pharmaceutical engineering Download PDFInfo
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- CN220310171U CN220310171U CN202321838871.1U CN202321838871U CN220310171U CN 220310171 U CN220310171 U CN 220310171U CN 202321838871 U CN202321838871 U CN 202321838871U CN 220310171 U CN220310171 U CN 220310171U
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- fixedly connected
- stirring
- stirring tank
- wall
- raw material
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- 238000003756 stirring Methods 0.000 title claims abstract description 86
- 239000002994 raw material Substances 0.000 title claims abstract description 46
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 20
- KEJCWVGMRLCZQQ-YJBYXUATSA-N Cefuroxime axetil Chemical compound N([C@@H]1C(N2C(=C(COC(N)=O)CS[C@@H]21)C(=O)OC(C)OC(C)=O)=O)C(=O)\C(=N/OC)C1=CC=CO1 KEJCWVGMRLCZQQ-YJBYXUATSA-N 0.000 title description 8
- 229960002620 cefuroxime axetil Drugs 0.000 title description 8
- 238000007790 scraping Methods 0.000 claims abstract description 10
- WDLWHQDACQUCJR-ZAMMOSSLSA-N (6r,7r)-7-[[(2r)-2-azaniumyl-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(e)-prop-1-enyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)/C=C/C)C(O)=O)=CC=C(O)C=C1 WDLWHQDACQUCJR-ZAMMOSSLSA-N 0.000 claims abstract 4
- 229960002580 cefprozil Drugs 0.000 claims abstract 4
- 229930186147 Cephalosporin Natural products 0.000 claims description 8
- 229940124587 cephalosporin Drugs 0.000 claims description 8
- 150000001780 cephalosporins Chemical class 0.000 claims description 8
- 238000007789 sealing Methods 0.000 claims description 5
- 239000000463 material Substances 0.000 abstract description 42
- 230000000694 effects Effects 0.000 abstract description 4
- 238000000034 method Methods 0.000 abstract description 2
- OKBVVJOGVLARMR-QSWIMTSFSA-N cefixime Chemical compound S1C(N)=NC(C(=N\OCC(O)=O)\C(=O)N[C@@H]2C(N3C(=C(C=C)CS[C@@H]32)C(O)=O)=O)=C1 OKBVVJOGVLARMR-QSWIMTSFSA-N 0.000 description 7
- 229960002129 cefixime Drugs 0.000 description 7
- 230000005540 biological transmission Effects 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 241000193830 Bacillus <bacterium> Species 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 238000007599 discharging Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 229940041008 second-generation cephalosporins Drugs 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 206010061695 Biliary tract infection Diseases 0.000 description 1
- 241001478240 Coccus Species 0.000 description 1
- 108090000204 Dipeptidase 1 Proteins 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 102000006635 beta-lactamase Human genes 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 208000003167 cholangitis Diseases 0.000 description 1
- 239000007919 dispersible tablet Substances 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 208000020029 respiratory tract infectious disease Diseases 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 208000019206 urinary tract infection Diseases 0.000 description 1
Landscapes
- Accessories For Mixers (AREA)
- Mixers Of The Rotary Stirring Type (AREA)
Abstract
The utility model discloses a raw material stirring device for cefprozil production for pharmaceutical engineering, which comprises a material receiving box, wherein the top of the material receiving box is fixedly connected with an installing table, the left side of the material receiving box is fixedly connected with a fixed column, the top of the fixed column is fixedly connected with a supporting column, the middle part of the right side of the supporting column is provided with a connecting box, the right side of the connecting box is provided with a stirring tank, a scraping plate outside the stirring frame can scrape raw materials on the inner wall of the stirring tank, the condition that the mixing effect is reduced due to the adhesion of the scraping plate on the inner wall of the stirring tank in the mixing process is avoided, the top and the bottom of the stirring tank can be rotated and changed, the raw materials at the bottom of the inner cavity of the stirring tank can be more directly stirred and fully stirred, the full stirring mode is more direct, the mixing efficiency is greatly improved, a filter cartridge can further filter the discharged raw materials, and the quality of the discharged raw materials can be improved.
Description
Technical Field
The utility model relates to the technical field of cefixime production and processing, in particular to a raw material stirring device for cefixime production in pharmaceutical engineering.
Background
Cefixime is a third-generation cephalosporin antibiotic for oral administration, and is suitable for treating respiratory, urinary and biliary tract infections caused by sensitive bacteria. Cefixime is highly stable to beta-lactamase produced by gram-negative bacillus, has stronger antibacterial effect to gram-negative bacillus than the first generation and the second generation cephalosporins, has lower antibacterial effect to gram-positive coccus than the first generation and the second generation cephalosporins, and is available in various dosage forms such as tablets, capsules, dispersible tablets, dry suspension, granules and the like approved by the national food and drug administration at present. When cefixime is produced, a stirring device is needed to stir raw materials.
In the prior art, raw materials stirring device for cefixime production for pharmaceutical engineering can not stir the raw materials at the bottom effectively, so that the raw materials at the bottom can not be stirred sufficiently, the stirring effect is reduced, application number 202020094471.4 discloses a raw materials stirring device for cefixime production for pharmaceutical engineering, which comprises a shell, connecting rods are arranged at four corners of the upper surface of the shell, a mounting plate is arranged at the top end of the connecting rod, a gear motor is arranged at the center of the upper surface of the mounting plate, an output shaft of the gear motor penetrates through a through hole in the mounting plate and is connected with a second rotating shaft through a coupler, the bottom end of the second rotating shaft penetrates through a bearing on the shell and is positioned in the shell, a transmission gear is arranged above the outer wall of the second rotating shaft, driven gears are arranged at two sides of the transmission gear, and the transmission gear is in meshed transmission connection with the driven gears; the device conveys the liquid medicine at the bottom to the upper part through the spiral, but the upward conveying effect and efficiency are insufficient, particles which are not mixed are adhered to the inner wall of the shell, the particles are difficult to fully mix, the discharging structure is not provided with a filtering mechanism, and the discharging quality is easy to be reduced.
For the problems in the related art, no effective solution has been proposed at present.
Disclosure of Invention
Aiming at the problems in the related art, the utility model provides a raw material stirring device for cefuroxime axetil production for pharmaceutical engineering, which aims to overcome the technical problems in the prior related art.
For this purpose, the utility model adopts the following specific technical scheme:
the utility model provides a raw material mixing device of cephalosporin production for pharmaceutical engineering, includes connects the workbin, connect workbin top fixedly connected with mount table, connect workbin left side fixedly connected with fixed column, fixed column top fixedly connected with support column, support column right side middle part is equipped with the connection box, the connection box right side is equipped with the agitator tank, agitator tank top right side is equipped with the conveying pipeline through the solenoid valve, connect the workbin right side to be equipped with and connect the silo.
Preferably, the middle part of the top side of the stirring tank is fixedly connected with a first motor, an output shaft of the first motor stretches into the inner cavity of the stirring tank and is fixedly connected with a rotating shaft, stirring frames are symmetrically arranged on the outer wall of the rotating shaft, and a scraping plate is fixedly connected to the outer side of the stirring frames.
Preferably, the scraping plate is movably attached to the inner wall of the stirring tank, a storage battery is arranged on one side of the top of the stirring tank, the storage battery is electrically connected with the first motor through a wire, and a sealing plug is fixedly clamped in the top opening of the conveying pipe.
Preferably, the left side of the inner wall of the connecting box is connected with a shaft rod through a bearing, the left side of the supporting column is fixedly connected with a second motor, the output shaft of the second motor and the outer wall of the shaft rod are respectively sleeved with and fixed with gears, the gears are meshed with each other, and the shaft rod penetrates through the outer side of the connecting box and is fixedly connected with the stirring tank.
Preferably, the middle part of the top side of the mounting table is communicated with a hose, two ends of the hose are respectively provided with a connecting ring through bearing sleeves, the top end of the hose is fixedly connected with an external threaded pipe on the top side edge of the connecting ring, and the bottom end of the hose is fixedly connected with a filter cartridge on the bottom side edge of the connecting ring.
Preferably, a thread groove is formed in the inner wall of the conveying pipe, the conveying pipe is in threaded connection with the external thread pipe in a matched mode through the thread groove, the bottom end of the hose extends into the receiving groove, and the filter cartridge is located on the top side of the inner cavity of the receiving groove.
The beneficial effects of the utility model are as follows: the stirring frame outside scrape the flitch and can strike off the raw materials on the agitator tank inner wall, avoid leading to the condition that the mixing effect descends on the agitator tank inner wall at the in-process adhesion, can make the top of agitator tank carry out rotatory transformation with the bottom, make the residual raw materials of bottom change top position, can be more direct stir the raw materials of agitator tank inner chamber bottom and mix, make the raw materials of bottom can carry out abundant stirring, the intensive stirring mode is more direct, mixing efficiency improves greatly, can pass through the hose with the raw materials in the agitator tank inner chamber and discharge, the cartridge filter can carry out further filtration operation to the discharged raw materials, can improve the quality of discharged raw materials.
Drawings
In order to more clearly illustrate the embodiments of the present utility model or the technical solutions in the prior art, the drawings that are needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present utility model, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
Fig. 1 is a schematic diagram showing the general structure of a raw material stirring device for cefuroxime axetil production for pharmaceutical engineering according to an embodiment of the present utility model;
fig. 2 is a schematic diagram of the internal structure of a stirring tank of a raw material stirring device for cefuroxime axetil production for pharmaceutical engineering according to an embodiment of the utility model;
fig. 3 is a schematic view showing the internal structure of a connection box of a raw material stirring device for cefuroxime axetil production in pharmaceutical engineering according to an embodiment of the present utility model;
fig. 4 is a schematic diagram of the internal structure of a receiving tank of a raw material stirring device for cefuroxime axetil production in pharmaceutical engineering according to an embodiment of the utility model.
In the figure:
1. a material receiving box; 2. a mounting table; 3. fixing the column; 4. a support column; 5. a connection box; 6. a stirring tank; 7. a material conveying pipe; 8. a receiving groove; 9. a first motor; 10. a rotating shaft; 11. a stirring frame; 12. a scraping plate; 13. a storage battery; 14. a sealing plug; 15. a shaft lever; 16. a second motor; 17. a gear; 18. a hose; 19. a connecting ring; 20. an external threaded tube; 21. a filter cartridge.
Detailed Description
For the purpose of further illustrating the various embodiments, the present utility model provides the accompanying drawings, which are a part of the disclosure of the present utility model, and which are mainly used to illustrate the embodiments and, together with the description, serve to explain the principles of the embodiments, and with reference to these descriptions, one skilled in the art will recognize other possible implementations and advantages of the present utility model, wherein elements are not drawn to scale, and like reference numerals are generally used to designate like elements.
According to the embodiment of the utility model, a raw material stirring device for cefuroxime axetil production for pharmaceutical engineering is provided.
Example 1
As shown in fig. 1-4, a raw material stirring device for cephalosporin production for pharmaceutical engineering according to the embodiment of the utility model comprises a material receiving box 1, a mounting table 2 is fixedly connected to the top of the material receiving box 1, a fixed column 3 is fixedly connected to the left side of the material receiving box 1, a support column 4 is fixedly connected to the top of the fixed column 3, a connecting box 5 is arranged in the middle of the right side of the support column 4, a stirring tank 6 is arranged on the right side of the connecting box 5, a material conveying pipe 7 is arranged on the right side of the top of the stirring tank 6 through an electromagnetic valve, a material receiving groove 8 is arranged on the right side of the material receiving box 1, a first motor 9 is fixedly connected to the middle of the top side of the stirring tank 6, an output shaft of the first motor 9 stretches into the inner cavity of the stirring tank 6, a rotating shaft 10 is fixedly connected to the rotating shaft 10, a stirring frame 11 is symmetrically arranged on the outer wall of the rotating shaft 10, a scraping plate 12 is fixedly connected to the outer side of the stirring frame 11, the scraping plate 12 is movably attached to the inner wall of the stirring tank 6, a sealing plug 14 is arranged on one side of the top of the stirring tank 6, the storage battery 13 is electrically connected with the first motor 9 through a wire, the sealing plug 14 is fixedly clamped in the top of the material conveying pipe 7, raw materials are injected into the stirring tank 6 through the conveying pipe 9, the stirring shaft 9, the output shaft 9 is started, the rotating shaft of the first motor 9 drives the rotating shaft 10 to rotate the rotating shaft 10 to the rotating shaft 10 to the stirring plate to the stirring frame 11 on the inner wall of the stirring frame 11, and the inner wall of the stirring frame is prevented from being mixed material is adhered to the inner wall of the stirring frame 11.
Example two
As shown in fig. 1-4, a raw material stirring device for producing cephalosporin for pharmaceutical engineering according to an embodiment of the utility model comprises a receiving box 1, a mounting table 2 is fixedly connected to the top of the receiving box 1, a fixed column 3 is fixedly connected to the left side of the receiving box 1, a support column 4 is fixedly connected to the top of the fixed column 3, a connecting box 5 is arranged in the middle of the right side of the support column 4, a stirring tank 6 is arranged on the right side of the connecting box 5, a material conveying pipe 7 is arranged on the right side of the top of the stirring tank 6 through an electromagnetic valve, a material receiving groove 8 is arranged on the right side of the receiving box 1, a shaft lever 15 is connected to the left side of the inner wall of the connecting box 5 through a bearing, a second motor 16 is fixedly connected to the left side of the support column 4, a gear 17 is respectively sleeved and fixed on the output shaft of the second motor 16 and the outer wall of the shaft lever 15, the gear 17 is meshed with each other, the shaft lever 15 penetrates through the outer side of the connecting box 5 and is fixedly connected with the stirring tank 6, the second motor 16 is started, the gear 17 on the outer wall of the output shaft of the second motor 16 drives the gear 17 on the outer wall of the shaft lever 15 to rotate, the stirring tank 6 connected with the shaft lever 15 can rotate outside the supporting column 4, the top and the bottom of the stirring tank 6 can be rotated and transformed, residual raw materials at the bottom are transformed into the top position, the raw materials at the bottom of the inner cavity of the stirring tank 6 can be stirred and mixed more directly, the raw materials at the bottom can be sufficiently stirred, the full stirring mode is more direct, and the mixing efficiency is greatly improved.
Example III
As shown in fig. 1-4, a raw material stirring device for cephalosporin production for pharmaceutical engineering according to an embodiment of the utility model comprises a material receiving box 1, a mounting table 2 is fixedly connected to the top of the material receiving box 1, a fixing column 3 is fixedly connected to the left side of the material receiving box 1, a supporting column 4 is fixedly connected to the top of the fixing column 3, a connecting box 5 is arranged in the middle of the right side of the supporting column 4, a stirring tank 6 is arranged on the right side of the connecting box 5, a material conveying pipe 7 is arranged on the right side of the top of the stirring tank 6 through an electromagnetic valve, a material receiving groove 8 is arranged on the right side of the material receiving box 1, a hose 18 is arranged in the middle of the top side of the mounting table 2 in a penetrating manner, connecting rings 19 are respectively arranged at two ends of the hose 18 through bearing sleeves, a thread groove 20 is formed in the top side edge of the top connecting ring 19, a thread groove is formed in the bottom end edge of the bottom connecting ring 19, a thread groove is formed in the inner wall of the material conveying pipe 7, the material conveying pipe 7 is in matched thread connection with the thread groove 20, the bottom end of the material conveying pipe 18 stretches into the inside the material receiving groove 8, the bottom of the hose 18 is positioned on the top side of the inner cavity of the material receiving groove 8, the material receiving groove is placed into the inside the material receiving groove 8, the material receiving groove 21 is inserted into the top of the material receiving groove, the material receiving groove 19 is inserted into the top of the material receiving groove, the material receiving groove through the material receiving groove, the material receiving groove 19, the material receiving the material groove is rotated into the material receiving groove and the inner cavity 6, and the material can be discharged through the thread groove and the thread groove 20, and can be further discharged through the thread groove 20.
In summary, by means of the above technical scheme of the utility model, when the device is used, raw materials are injected into the stirring tank 6 through the material conveying pipe 7, the first motor 9 is started, the output shaft of the first motor 9 drives the rotating shaft 10 to rotate, the stirring frame 11 on the outer wall of the rotating shaft 10 stirs and mixes the raw materials, the scraping plate 12 on the outer side of the stirring frame 11 can scrape the raw materials on the inner wall of the stirring tank 6, the second motor 16 is started, the gear 17 on the outer wall of the output shaft of the second motor 16 drives the gear 17 on the outer wall of the shaft rod 15 to drive and rotate, the stirring tank 6 connected with the shaft rod 15 can rotate on the outer side of the supporting column 4, the top and the bottom of the stirring tank 6 can be rotated and changed, the residual raw materials at the bottom can be changed into the top position, the raw materials at the bottom of the inner cavity of the stirring tank 6 can be more directly stirred and mixed, the collected tank body is placed into the receiving tank 8, the filter cartridge 21 is inserted into the top opening of the collecting tank body, after the top of the stirring tank 6 rotates to the lower side, the outer thread pipe 20 is matched with the inner wall of the material conveying pipe 7 in a sleeved mode, the inner wall of the material conveying pipe 7 can be further discharged through the outer thread pipe 20, and the raw materials in the inner cavity of the stirring tank 6 can be discharged through the filter tube 18, and the filter tube can be further operated.
The foregoing description of the preferred embodiments of the utility model is not intended to be limiting, but rather is intended to cover all modifications, equivalents, alternatives, and improvements that fall within the spirit and scope of the utility model.
Claims (6)
1. The utility model provides a raw material mixing device for cephalosporin production for pharmaceutical engineering, includes connects workbin (1), its characterized in that, connect workbin (1) top fixedly connected with mount table (2), connect workbin (1) left side fixedly connected with fixed column (3), fixed column (3) top fixedly connected with support column (4), support column (4) right side middle part is equipped with connecting box (5), connecting box (5) right side is equipped with agitator tank (6), agitator tank (6) top right side is equipped with conveying pipeline (7) through the solenoid valve, connect workbin (1) right side to be equipped with and connect silo (8).
2. The raw material stirring device for cefprozil production for pharmaceutical engineering according to claim 1, wherein a first motor (9) is fixedly connected to the middle part of the top side of the stirring tank (6), an output shaft of the first motor (9) stretches into an inner cavity of the stirring tank (6) and is fixedly connected with a rotating shaft (10), stirring frames (11) are symmetrically arranged on the outer wall of the rotating shaft (10), and scraping plates (12) are fixedly connected to the outer side of the stirring frames (11).
3. The raw material stirring device for producing cephalosporin for pharmaceutical engineering according to claim 2, wherein the scraping plate (12) is movably attached to the inner wall of the stirring tank (6), a storage battery (13) is arranged on one side of the top of the stirring tank (6), the storage battery (13) is electrically connected with the first motor (9) through a wire, and a sealing plug (14) is fixedly clamped in the top opening of the conveying pipe (7).
4. A raw material stirring device for producing cephalosporin for pharmaceutical engineering according to claim 3, characterized in that the left side of the inner wall of the connecting box (5) is connected with a shaft lever (15) through a bearing, the left side of the supporting column (4) is fixedly connected with a second motor (16), the output shaft of the second motor (16) and the outer wall of the shaft lever (15) are respectively sleeved and fixed with a gear (17), the gears (17) are meshed with each other, and the shaft lever (15) penetrates through the outer side of the connecting box (5) and is fixedly connected with a stirring tank (6).
5. The raw material stirring device for cefprozil production for pharmaceutical engineering according to claim 4, wherein a hose (18) is arranged in the middle of the top side of the mounting table (2), two ends of the hose (18) are respectively provided with a connecting ring (19) through bearing sleeves, the top end of the connecting ring (19) is fixedly connected with an external thread pipe (20), and the bottom end of the connecting ring (19) is fixedly connected with a filter cartridge (21).
6. The raw material stirring device for cefprozil production for pharmaceutical engineering according to claim 5, wherein a threaded groove is formed in the inner wall of the conveying pipe (7), the conveying pipe (7) is in threaded connection with the external threaded pipe (20) in a matched mode through the threaded groove, the bottom end of the hose (18) stretches into the receiving groove (8), and the filter cylinder (21) is located at the top side of the inner cavity of the receiving groove (8).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321838871.1U CN220310171U (en) | 2023-07-13 | 2023-07-13 | Raw material stirring device for cefuroxime axetil production for pharmaceutical engineering |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321838871.1U CN220310171U (en) | 2023-07-13 | 2023-07-13 | Raw material stirring device for cefuroxime axetil production for pharmaceutical engineering |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220310171U true CN220310171U (en) | 2024-01-09 |
Family
ID=89423442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321838871.1U Active CN220310171U (en) | 2023-07-13 | 2023-07-13 | Raw material stirring device for cefuroxime axetil production for pharmaceutical engineering |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220310171U (en) |
-
2023
- 2023-07-13 CN CN202321838871.1U patent/CN220310171U/en active Active
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