CN108676697A - A kind of biological respinse and bio-separation device - Google Patents

A kind of biological respinse and bio-separation device Download PDF

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Publication number
CN108676697A
CN108676697A CN201810296918.3A CN201810296918A CN108676697A CN 108676697 A CN108676697 A CN 108676697A CN 201810296918 A CN201810296918 A CN 201810296918A CN 108676697 A CN108676697 A CN 108676697A
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space
biological respinse
fixedly connected
annular
stirring
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洪杰
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/48Holding appliances; Racks; Supports
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02Stirrer or mobile mixing elements
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04Filters; Permeable or porous membranes or plates, e.g. dialysis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/04Seals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18Heat exchange systems, e.g. heat jackets or outer envelopes
    • C12M41/22Heat exchange systems, e.g. heat jackets or outer envelopes in contact with the bioreactor walls
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10Separation or concentration of fermentation products

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • General Engineering & Computer Science (AREA)
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  • Thermal Sciences (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention discloses a kind of biological respinses and bio-separation device, including fixed bottom plate, it is fixedly installed a reaction unit on the left of the fixed bottom plate upper surface, the reaction unit includes cylindrical seal tank, the cylindrical seal tank is internally provided with a biological reaction chamber, the middle position in biological respinse intracavitary portion is provided with a flowing shell, the flowing enclosure interior is provided with a stirring space up and down, spiral winding has a cooling tube on the cylindroid of the flowing hull outside, it is fixedly connected with a cold water storage cistern on fixation bottom plate on rear side of the cylindrical seal tank, detachable connection has a filter cartridge in the sealing hole, the separator includes static housing, upside inside the static housing is provided with a centrifugal space.In present invention work, biological respinse intracavitary portion forms and circulates, ensure the uniform of stirring, be conducive to the efficient progress of biological respinse, suitable temperature is provided for the survival of microorganism, the culture solution of biological respinse intracavitary through filtering leave excreta etc. unwanted particulate matter, to isolated required effective ingredient.

Description

A kind of biological respinse and bio-separation device
Technical field
The present invention relates to field of biological pharmacy, specially a kind of biological respinse and bio-separation device.
Background technology
Currently, in daily life, bio-pharmaceuticals is generally connect by its good effect, non-hazardous effect by people By, and during bio-pharmaceuticals, required for generally being obtained by the promotion functions of the culture of biological cell or biological enzyme Pharmaceutical compositions, existing culture tank all be mechanical stirring rod stir, mixing effect is poor, can not be stirred to all positions in tank It sets, and the shearing force of stirring rod can cause the death of cell, reduces reaction speed, will produce heat during biological respinse Amount, needs to radiate in time, and the product after biological respinse also needs to be detached.
Invention content
The purpose of the present invention is to provide a kind of biological respinses and bio-separation device, to solve to carry in above-mentioned background technology The problem of going out.
To achieve the above object, the present invention provides the following technical solutions:A kind of biological respinse and bio-separation device, including Bottom plate is fixed, a reaction unit, the right side of the fixed bottom plate upper surface are fixedly installed on the left of the fixed bottom plate upper surface Side is fixedly installed a separator, and the reaction unit includes cylindrical seal tank, and the cylindrical seal tank is internally provided with one Biological respinse chamber, is provided with an annular fixing groove on the downside of the cylindrical seal tank cylindroid, solid inside the annular fixing groove Surely it is connected with a ring-type fixing plate, the outside of the ring-type fixing plate is located at outside annular fixing groove, and under the ring-type fixing plate The outer circumference direction of end face is uniformly distributed there are four support column, and the lower end of the support column is solid with the upper surface of fixed bottom plate Fixed connection, the middle position of cylindrical seal tank upper surface are provided with a feed pipe extended to the left, in the feed pipe It is provided with a feed opening, the feed opening is connected to biological respinse chamber, a feeding seal valve is provided at the tube body of the feed pipe, The middle position in biological respinse intracavitary portion is provided with a flowing shell, and the flowing enclosure interior is provided with about one and passes through The middle position of logical stirring space, the stirring space lower end is provided with a motor housing, and the motor housing passes through its left and right The symmetrically arranged connecting rod in both ends is fixedly connected with the inner wall of stirring space, the middle position setting of the stirring space upper end There are a link block, the link block to be fixedly connected with the inner wall of stirring space by the symmetrically arranged fixed link in its left and right ends, The motor housing is internally provided with a stirring motor, and the stirring motor upper end is provided with a rotary shaft, the rotary shaft it is upper End is pierced by motor housing and is fixedly connected with the center position rotary type of link block lower face, is arranged on the axis body of the rotary shaft There is a spiralling paddle, the middle position of the flowing shell cylindroid is symmetrically set with supporting rod, described The outside of supporting rod is fixedly connected with the inner wall of biological respinse chamber, there is spiral winding on the cylindroid of the flowing hull outside One cooling tube, is fixedly connected with a cold water storage cistern on the fixation bottom plate on rear side of the cylindrical seal tank, setting inside the cold water storage cistern There is a water space, the lower end of the cold water storage cistern front end face is fixedly connected with a hydraulic pump, under the water space front bulkhead End is provided with a connecting hole, and the connecting hole connection hydraulic pump and water space, the hydraulic pump front end are connected with a water inlet pipe, The front end of the water inlet pipe passes through the downside of biological respinse cavity rear end wall and is fixedly connected with the lower end of cooling tube, the water inlet pipe It is internally provided with a solenoid valve, the upper end of the cooling tube is fixedly connected with outlet pipe, and the rear end of the outlet pipe passes through biology It the upside of reaction chamber aft bulkhead and is connect with the upper surface of cold water storage cistern, the outlet pipe connection water space and cooling tube are described The downside of biological respinse cavity rear end wall is embedded to be equipped with a temperature inductor, the center of the biological respinse chamber lower end wall Place is provided with a sealing hole, and detachable connection has a filter cartridge in the sealing hole, and an opening is provided in the filter cartridge Upward lautertuns, the lautertuns is connected to biological respinse chamber, and a filter screen is equipped with inside the lautertuns, the filtering The center position of box lower face is fixedly connected with one and extends drain pipe to the right, and the drainage hole is connected to lautertuns, and the row An electric control valve is provided in fluid apertures, the separator includes static housing, and the upside inside the static housing is provided with One centrifugal space, the centrifugal space lower end wall are internally provided with a high pressure inlet opening extended to the left, the static housing The lower end of left side is fixedly connected with a liquid booster pump, the high pressure inlet opening connection liquid booster pump and centrifugal space, institute The left end for stating liquid booster pump is connected to drain pipe, and the centrifugal space lower end is provided with ring rotation disk, the ring rotation Circle distribution has multiple swinging plates, ring rotation disk lower face to be arranged at paracentral position on the annular surface of disk upper end There are an annular T blocks, an annular link slot, institute are provided at centrifugal space lower end wall position corresponding with annular T blocks It states annular T blocks to be connected with annular link slot, ring rotation disk lower face is provided with one at deep position Internal gear is provided with a ring rotation slot at centrifugal space lower end wall position corresponding with internal gear, and the internal gear is located at ring In shape swivelling chute, the right side inside the centrifugal space lower end wall is provided with a driving space, fixes and sets in the driving space It is equipped with a driving motor, the driving space upper end wall is internally provided with a driving groove, the right end connected ring of the driving groove The inside of shape swivelling chute, the driving motor upper end are provided with a transmission shaft, and the upper end of the transmission shaft passes through driving space Upper end wall and with the transmission gear be connected by power in driving groove, the right end of the transmission gear is pierced by driving groove and passed with internal gear Dynamic to be connected, the center position of the static housing upper surface is provided with a lightweight liquid discharge port, on the static housing The left end of end face is provided with a heavy liquid discharge port, and the lightweight liquid discharge port is connected to centrifugal space with heavy liquid discharge port.
Preferably, the diameter of the paddle is equal to the cross-sectional diameter of stirring space.
Preferably, the temperature inductor connects hydraulic pump and solenoid valve by circuit.
Preferably, the sealing hole is divided into two kinds of connection structures up and down with filter cartridge connecting portion, top junction is It is threadedly coupled, lower part junction is to be tightly connected, and airtight rubber circle is set on the cylindroid of the corresponding filter cartridge.
Compared with prior art, the beneficial effects of the invention are as follows:In present invention work, by opening filter cartridge, in biology It is packed into biological enzyme or biological cell in reaction compartment, by feed opening, required culture medium is packed into biological respinse space, is made Used time, stirring motor work drive paddle rotation, the liquid in stirring space to move to upper end from lower end by rotary shaft, It is moved downward again by biological respinse chamber, while so that liquid is obtained stirring, is formed and circulated in biological respinse intracavitary portion, protected Card stirs uniform, is conducive to the efficient progress of biological respinse, meanwhile, temperature inductor receives the liquid in biological respinse intracavitary portion Temperature, when the temperature is excessively high, hydraulic pump works, the cold water extracted in water space enters cooling tube, cooling tube by water inlet pipe Middle cold water completes the exchange of heat during spiral, to achieve the purpose that cooling biological respinse intracavitary culture solution, Suitable temperature is provided for the survival of microorganism, the cell death under overheat condition is avoided, is efficiently completed biological respinse, is reacted After the completion, electric control valve is opened, the culture solution of biological respinse intracavitary by filter screen filtration leave excreta etc. it is unwanted Particulate matter enters drain pipe by filtered culture solution, then by entering centrifugal space after liquid booster pump, at this point, driving Motor works, and is rotated by transmission shaft band nutating gear, then drives ring rotation with engaging for internal gear by transmission gear Disk and swinging plate rotation, to drive the culture solution in centrifugal space to move in a circle, during circumferentially rising, heavy is molten Liquid is located at the outside of centrifugal space under the effect of centrifugation, and is collected by heavy liquid discharge port, work of the lightweight solution in centrifugation It with lower positioned at the inside of centrifugal space, and is collected by lightweight liquid discharge port, to isolated required effective ingredient.
Description of the drawings
Fig. 1 is a kind of main structure diagram of biological respinse and bio-separation device entirety complete section of the present invention;
Fig. 2 is a kind of left view structural representation of biological respinse and bio-separation device entirety complete section of the present invention;
Fig. 3 is the main structure diagram of filter cartridge complete section in a kind of biological respinse of the present invention and bio-separation device;
Fig. 4 is the overlooking structure diagram of annular swivel plate in a kind of biological respinse of the present invention and bio-separation device;
Fig. 5 is the vertical view figure structure schematic representation of complete section in flowing shell in a kind of biological respinse of the present invention and separator.
Specific implementation mode
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation describes, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
- 5 are please referred to Fig.1, a kind of embodiment provided by the invention:A kind of biological respinse and bio-separation device, including it is solid Determine bottom plate 1, a reaction unit 2 is fixedly installed on the left of 1 upper surface of fixed bottom plate, 1 upper surface of fixed bottom plate Right side is fixedly installed a separator 3, and the reaction unit 2 includes cylindrical seal tank 4, is set inside the cylindrical seal tank 4 It is equipped with a biological reaction chamber 5, an annular fixing groove 6 is provided on the downside of 4 cylindroid of cylindrical seal tank, the annular is fixed A ring-type fixing plate 7 is fixedly connected with inside slot 6, the outside of the ring-type fixing plate 7 is located at outside annular fixing groove 6, and described The outer circumference direction of 7 lower face of ring-type fixing plate is uniformly distributed there are four support column 8, the lower end of the support column 8 with it is solid The upper surface for determining bottom plate 1 is fixedly connected, the middle position of 4 upper surface of cylindrical seal tank be provided with one extend to the left into Expects pipe 9 is provided with a feed opening 10 in the feed pipe 9, and the feed opening 10 is connected to biological respinse chamber 5, the feed pipe 9 A feeding seal valve 11 is provided at tube body, the middle position inside the biological respinse chamber 5 is provided with a flowing shell 12, The flowing shell 12 is internally provided with a stirring space 13 up and down, the middle position of 13 lower end of the stirring space It is provided with a motor housing 14, the motor housing 14 passes through in the symmetrically arranged connecting rod 15 in its left and right ends and stirring space 13 Wall is fixedly connected, and the middle position of 13 upper end of the stirring space is provided with a link block 16, and the link block 16 passes through it The symmetrically arranged fixed link 17 in left and right ends is fixedly connected with the inner wall of stirring space 13, and the motor housing 14 is internally provided with one Stirring motor 18,18 upper end of the stirring motor are provided with a rotary shaft 19, and the upper end of the rotary shaft 19 is pierced by motor housing 14 And be fixedly connected with the center position rotary type of 16 lower face of link block, a spiral is provided on the axis body of the rotary shaft 19 The middle position of the paddle 20 of rising, flowing 12 cylindroid of shell is symmetrically set with supporting rod 21, the branch The outside of strut 21 is fixedly connected with the inner wall of biological respinse chamber 5, and spiral twines on the cylindroid in 12 outside of flowing shell It is wound with a cooling tube 22, a cold water storage cistern 23, the cold water are fixedly connected on the fixation bottom plate 1 of 4 rear side of the cylindrical seal tank Case 23 is internally provided with a water space 24, and the lower end of 23 front end face of the cold water storage cistern is fixedly connected with a hydraulic pump 25, described The lower end of 24 front bulkhead of water space is provided with a connecting hole 26, and the connecting hole 26 is connected to hydraulic pump 25 and water space 24, 25 front end of the hydraulic pump is connected with a water inlet pipe 27, and the front end of the water inlet pipe 27 passes through under 5 aft bulkhead of biological respinse chamber It side and is fixedly connected with the lower end of cooling tube 22, the water inlet pipe 27 is internally provided with a solenoid valve 28, the cooling tube 22 Upper end is fixedly connected with outlet pipe 29, and the rear end of the outlet pipe 29 passes through upside and and the cold water of 5 aft bulkhead of biological respinse chamber The upper surface of case 23 connects, and the outlet pipe 29 is connected to water space 24 and cooling tube 22,5 aft bulkhead of biological respinse chamber Downside is embedded to be equipped with a temperature inductor 30, and the center position of 5 lower end wall of biological respinse chamber is provided with a sealing Hole 31, detachable connection has a filter cartridge 32 in the sealing hole 31, and an opening upwards are provided in the filter cartridge 32 Lautertuns 33, the lautertuns 33 is connected to biological respinse chamber 5, and a filter screen 34 is equipped with inside the lautertuns 33, described The center position of 32 lower face of filter cartridge is fixedly connected with one and extends drain pipe 35 to the right, and the drainage hole 35 is connected to lautertuns 33, and an electric control valve 36 is provided in the drainage hole 35, the separator 3 includes static housing 37, the fixed case Upside inside body 37 is provided with a centrifugal space 38, and being internally provided with for 38 lower end wall of the centrifugal space one extends to the left The lower end of high pressure inlet opening 39,37 left side of the static housing is fixedly connected with a liquid booster pump 40, the high pressure feed liquor Hole 39 is connected to liquid booster pump 40 and centrifugal space 38, the left end of the liquid booster pump 40 and is connected to drain pipe 35, it is described from 38 lower end of heart space is provided with ring rotation disk 41, and circle distribution has multiple groups on the annular surface of 41 upper end of ring rotation disk Movable plate 42,41 lower face of ring rotation disk are provided with an annular T blocks 43, the centrifugal space at paracentral position An annular link slot 44 is provided at 38 lower end walls position corresponding with annular T blocks 43, the annular T blocks 43 connect with annular Access slot 44 is connected, and an internal gear 45 is provided at the deep position in 41 lower face of ring rotation disk, and centrifugation is empty Between be provided with a ring rotation slot 46 at 38 lower end walls position corresponding with internal gear 45, the internal gear 45 is located at ring rotation In slot 46, the right side inside 38 lower end wall of the centrifugal space is provided with a driving space 47, is fixed in the driving space 47 It is provided with a driving motor 48, driving 47 upper end wall of space is internally provided with a driving groove 49, the driving groove 49 The inside of right end connection annular swivelling chute 46,48 upper end of the driving motor are provided with a transmission shaft 50, the transmission shaft 50 Upper end pass through driving space 47 upper end wall and with 51 be connected by power of transmission gear in driving groove 49, the transmission gear 51 Right end is pierced by driving groove 49 and is driven with internal gear 45 and is connected, the center position setting of 37 upper surface of the static housing There are a lightweight liquid discharge port 52, the left end of 37 upper surface of the static housing to be provided with a heavy liquid discharge port 53, the lightweight Liquid discharge port 52 is connected to centrifugal space 38 with heavy liquid discharge port 53.
Valuably, the diameter of the paddle 20 is equal to the cross-sectional diameter of stirring space 13.Its effect is stirring motor 18 work drive paddle 20 to rotate by rotary shaft 19, and the liquid in stirring space 13 moves to upper end from lower end, then passes through Biological respinse chamber 5 moves downward, and while so that liquid is obtained stirring, is formed and is circulated inside biological respinse chamber 5, ensure to stir That mixes is uniform, is conducive to the efficient progress of biological respinse.
Valuably, the temperature inductor 30 connects hydraulic pump 25 and solenoid valve 28 by circuit.Its effect is to pass through temperature The fluid temperature inside the reception biological respinse of inductor 30 chamber 5 is spent, when the temperature is excessively high, hydraulic pump 25 works, and it is empty to extract water storage Between cold water in 24 cooling tube 22 is entered by water inlet pipe 27, cold water completes heat during spiral in cooling tube 22 Exchange provide suitable temperature to achieve the purpose that culture solution in cooling biological respinse chamber 5 for the survival of microorganism, keep away Exempt from the cell death under overheat condition, is efficiently completed biological respinse.
Valuably, the sealing hole 31 is divided into two kinds of connection structures up and down, top junction with 32 connecting portion of filter cartridge To be threadedly coupled, lower part junction is to be tightly connected, and airtight rubber circle is set on the cylindroid of the corresponding filter cartridge 32 33.Its effect is to be connected through a screw thread, and filter cartridge 32 can be removed freely, convenient for removing the cell excretion that filter screen 34 filters Product ensures the normal use of filter screen 34, meanwhile, the filter screen more renewed 34 is also allowed for, airtight rubber circle 33 can ensure The air-tightness of filter cartridge 32 and 31 junction of sealing hole, ensures that the leakproofness in biological respinse space 5, prevents liquid from letting out Leakage or living contaminants.
Specifically used mode:In present invention work, by opening filter cartridge 32, biology is packed into biological respinse space 5 Enzyme or biological cell are packed into required culture medium, in use, stirring motor 18 by feed opening 10 in biological respinse space 5 Work drives paddle 20 to rotate by rotary shaft 19, and the liquid in stirring space 13 moves to upper end from lower end, then passes through life Object reaction chamber 5 moves downward, and while so that liquid is obtained stirring, is formed and is circulated inside biological respinse chamber 5, ensures stirring It is uniform, be conducive to the efficient progress of biological respinse, meanwhile, temperature inductor 30 receives the liquid temperature inside biological respinse chamber 5 Degree, when the temperature is excessively high, hydraulic pump 25 works, and the cold water extracted in water space 24 enters cooling tube 22 by water inlet pipe 27, Cold water completes the exchange of heat during spiral in cooling tube 22, to reach culture in cooling biological respinse chamber 5 The purpose of liquid provides suitable temperature for the survival of microorganism, avoids the cell death under overheat condition, be efficiently completed biology Reaction, after the completion of reaction, electric control valve 36 is opened, and the culture solution in biological respinse chamber 5 leaves excretion by the filtering of filter screen 34 Object etc. unwanted particulate matter, enter drain pipe 35 by filtered culture solution, then by entering after liquid booster pump 40 Centrifugal space 38 is rotated by transmission shaft 50 with nutating gear 51, then pass through transmission gear at this point, driving motor 48 works 51 drive ring rotation disk 41 and swinging plate 42 to rotate with engaging for internal gear 45, to drive the culture solution in centrifugal space 38 It moves in a circle, during circumferentially rising, heavy solution is located at the outside of centrifugal space 38 under the effect of centrifugation, and leads to The collection of heavy liquid discharge port 53 is crossed, lightweight solution is located at the inside of centrifugal space 38 under the effect of centrifugation, and passes through lightweight liquid Discharge port 52 is collected, to isolated required effective ingredient.
It is obvious to a person skilled in the art that invention is not limited to the details of the above exemplary embodiments, Er Qie In the case of without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power Profit requires rather than above description limits, it is intended that all by what is fallen within the meaning and scope of the equivalent requirements of the claims Variation is included within the present invention.Any reference signs in the claims should not be construed as limiting the involved claims.

Claims (4)

1. a kind of biological respinse and bio-separation device, including fixed bottom plate, it is characterised in that:The fixed bottom plate upper surface Left side is fixedly installed a reaction unit, and a separator is fixedly installed on the right side of the fixed bottom plate upper surface, described anti- It includes cylindrical seal tank to answer device, and the cylindrical seal tank is internally provided with a biological reaction chamber, the cylindrical seal tank cylindricality It is provided with an annular fixing groove on the downside of face, a ring-type fixing plate, the annular are fixedly connected with inside the annular fixing groove The outside of fixed plate is located at outside annular fixing groove, and the outer circumference direction of the ring-type fixing plate lower face is evenly distributed with four The lower end of a support column, the support column is fixedly connected with the upper surface of fixed bottom plate, cylindrical seal tank upper surface Middle position is provided with a feed pipe extended to the left, and a feed opening, the feed opening connection are provided in the feed pipe Biological respinse chamber is provided with a feeding seal valve, the centre position in biological respinse intracavitary portion at the tube body of the feed pipe Place is provided with a flowing shell, and the flowing enclosure interior is provided with a stirring space up and down, under the stirring space The middle position at end is provided with a motor housing, and the motor housing is empty with stirring by the symmetrically arranged connecting rod in its left and right ends Between inner wall be fixedly connected, the middle position of the stirring space upper end is provided with a link block, and the link block passes through it The symmetrically arranged fixed link in left and right ends is fixedly connected with the inner wall of stirring space, and the motor housing is internally provided with stirring electricity Machine, the stirring motor upper end are provided with a rotary shaft, the upper end of the rotary shaft be pierced by motor housing and with link block lower face Center position rotary type be fixedly connected, a spiralling paddle, the stream are provided on the axis body of the rotary shaft The middle position of dynamic shell cylindroid is symmetrically set with supporting rod, the outside of the supporting rod with biological respinse chamber Inner wall is fixedly connected, and spiral winding has a cooling tube, the cylindrical seal tank rear side on the cylindroid of the flowing hull outside Fixation bottom plate on be fixedly connected with a cold water storage cistern, the cold water storage cistern is internally provided with a water space, the cold water storage cistern front end The lower end in face is fixedly connected with a hydraulic pump, and the lower end of the water space front bulkhead is provided with a connecting hole, the connecting hole It is connected to hydraulic pump and water space, the hydraulic pump front end is connected with a water inlet pipe, and the front end of the water inlet pipe passes through biology anti- It answers the downside of cavity rear end wall and is fixedly connected with the lower end of cooling tube, the water inlet pipe is internally provided with a solenoid valve, described cold But the upper end of pipe is fixedly connected with outlet pipe, and the rear end of the outlet pipe passes through upside and and the cold water of biological respinse cavity rear end wall The upper surface of case connects, the outlet pipe connection water space and cooling tube, and the downside of the biological respinse cavity rear end wall is embedded Formula is equipped with a temperature inductor, and the center position of the biological respinse chamber lower end wall is provided with a sealing hole, the sealing Detachable connection has a filter cartridge in hole, and the lautertuns of an opening upwards is provided in the filter cartridge, and the lautertuns connects Logical biological respinse chamber, and a filter screen is installed inside the lautertuns, the center position of the filter cartridge lower face is fixed It is connected with one and extends drain pipe to the right, the drainage hole is connected to lautertuns, and is provided with an electric control valve in the drainage hole, institute It includes static housing to state separator, and the upside inside the static housing is provided with a centrifugal space, under the centrifugal space End wall is internally provided with a high pressure inlet opening extended to the left, and the lower end of the static housing left side is fixedly connected with a liquid Body booster pump, the high pressure inlet opening connection liquid booster pump and centrifugal space, the left end and drain pipe of the liquid booster pump Connection, the centrifugal space lower end are provided with ring rotation disk, there is circle distribution on the annular surface of ring rotation disk upper end Multiple swinging plates, ring rotation disk lower face are provided with an annular T blocks, the centrifugal space at paracentral position An annular link slot is provided at lower end wall position corresponding with annular T blocks, the annular T blocks coordinate with annular link slot It connects, an internal gear, centrifugal space lower end wall and internal tooth is provided at the deep position in ring rotation disk lower face A ring rotation slot is provided at the corresponding position of ring, the internal gear is located in ring rotation slot, the centrifugal space lower end It is provided with a driving space on the right side of pars intramuralis, a driving motor, the driving space are fixedly installed in the driving space Upper end wall is internally provided with a driving groove, the inside of the annular swivelling chute of right end connection of the driving groove, the driving motor Upper end is provided with a transmission shaft, the upper end of the transmission shaft pass through the upper end wall in driving space and with the transmission gear in driving groove Be connected by power, the right end of the transmission gear, which is pierced by driving groove and is driven with internal gear, to be connected, the static housing upper end The center position in face is provided with a lightweight liquid discharge port, and the left end of the static housing upper surface is provided with heavy liquid discharging Mouthful, the lightweight liquid discharge port is connected to centrifugal space with heavy liquid discharge port.
2. a kind of biological respinse according to claim 1 and bio-separation device, it is characterised in that:The paddle it is straight Diameter is equal to the cross-sectional diameter of stirring space.
3. a kind of biological respinse according to claim 1 and bio-separation device, it is characterised in that:The temperature inductor Hydraulic pump and solenoid valve are connected by circuit.
4. a kind of biological respinse according to claim 1 and bio-separation device, it is characterised in that:The sealing hole and mistake Filter box connecting portion is divided into two kinds of connection structures up and down, and top junction is to be threadedly coupled, and lower part junction is to be tightly connected, right Airtight rubber circle is set on the cylindroid for the filter cartridge answered.
CN201810296918.3A 2018-04-04 2018-04-04 A kind of biological respinse and bio-separation device Withdrawn CN108676697A (en)

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Application Number Priority Date Filing Date Title
CN201810296918.3A CN108676697A (en) 2018-04-04 2018-04-04 A kind of biological respinse and bio-separation device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810296918.3A CN108676697A (en) 2018-04-04 2018-04-04 A kind of biological respinse and bio-separation device

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CN108676697A true CN108676697A (en) 2018-10-19

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117547960A (en) * 2024-01-13 2024-02-13 福建众辉环保设备有限公司 Biocatalysis reaction environment-friendly deodorizing device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117547960A (en) * 2024-01-13 2024-02-13 福建众辉环保设备有限公司 Biocatalysis reaction environment-friendly deodorizing device
CN117547960B (en) * 2024-01-13 2024-04-09 福建众辉环保设备有限公司 Biocatalysis reaction environment-friendly deodorizing device

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