CN220294598U - Mixing structure and immunoassay appearance - Google Patents
Mixing structure and immunoassay appearance Download PDFInfo
- Publication number
- CN220294598U CN220294598U CN202321642666.8U CN202321642666U CN220294598U CN 220294598 U CN220294598 U CN 220294598U CN 202321642666 U CN202321642666 U CN 202321642666U CN 220294598 U CN220294598 U CN 220294598U
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- reaction cup
- driving unit
- mixing structure
- driving
- base
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- 238000002156 mixing Methods 0.000 title claims abstract description 27
- 238000003018 immunoassay Methods 0.000 title claims abstract description 10
- 239000000758 substrate Substances 0.000 claims abstract description 7
- 238000004140 cleaning Methods 0.000 abstract description 16
- 239000007788 liquid Substances 0.000 abstract description 16
- 239000011324 bead Substances 0.000 abstract description 9
- 239000000203 mixture Substances 0.000 abstract description 2
- 238000001514 detection method Methods 0.000 description 4
- 238000003745 diagnosis Methods 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000011435 rock Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
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- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The utility model discloses a mixing structure and an immunoassay analyzer, wherein the immunoassay analyzer comprises a mixing structure, the mixing structure comprises a fixed plate, and a support frame for placing a reaction cup is arranged on the fixed plate; the device comprises a reaction cup, a fixing plate, a first driving unit, a base, a first driving unit, a second driving unit, a first driving unit and a second driving unit, wherein the reaction cup is arranged on the fixing plate; the fixed plate is provided with a driving part for driving the shaking part to move up and down. According to the utility model, the cleaning liquid and the magnetic beads in the reaction cup are uniformly mixed through the shaking part, after uniform mixing, the mixture is separated from the bottom of the reaction cup through the downward movement of the substrate, the cleaning liquid and the redundant objects to be detected are removed, and after the completion, the reaction cup can be directly taken down from the fixing ring and replaced by a new reaction cup, so that the reaction cup is convenient and quick.
Description
Technical Field
The utility model belongs to the technical field of immunity analyzers, and particularly relates to a mixing structure and an immunity analyzer.
Background
In the in vitro diagnosis immunoassay, a detection sample (blood, body fluid, tissue and the like) is detected outside a human body to obtain diagnosis information, the detection sample is obtained by extracting an object to be detected by a magnetic bead method, and the object to be detected in the detection sample is adsorbed under the characteristics of the magnetic beads and the action of an external magnetic field, wherein the redundant object to be detected which is not adsorbed needs to be removed so as to avoid influencing detection data.
The existing mixing structure is used for better mixing, and the reaction cup is usually required to be fixed, so that the reaction cup is taken and placed more fussy, the working efficiency is affected, and improvement is required.
Disclosure of Invention
The utility model aims to provide a mixing structure so as to solve the problem that the existing mixing structure is inconvenient to take and place a reaction cup. A second object of the present utility model is to provide an immunoassay instrument.
In order to achieve the above purpose, the present utility model adopts the following technical scheme:
as a first aspect of the present utility model, a mixing structure is disclosed, comprising a fixing plate, wherein a supporting frame for placing a reaction cup is arranged on the fixing plate;
the device comprises a reaction cup, a fixing plate, a first driving unit, a base, a groove, a first driving unit and a second driving unit, wherein the shaking part is used for shaking the reaction cup and comprises a base plate, the base plate is connected with the fixing plate in a sliding mode, the output end of the first driving unit is connected with the base, the base is provided with the groove for placing the bottom of the reaction cup, and the center of the groove is arranged in a dislocation mode with the axis of the output shaft of the driving unit;
the fixed plate is provided with a driving part for driving the shaking part to move up and down.
Optionally, the device further comprises a follow-up bearing, wherein the follow-up bearing is detachably connected with the base plate, the driving part comprises a second driving unit, the second driving unit is detachably connected with the fixed plate, and the output end of the second driving unit is connected with an eccentric wheel matched with the follow-up bearing.
Optionally, be equipped with the slide rail on the fixed plate, rock the portion still include with slide rail matched with slider, the slider with the base plate can dismantle the connection, rock the portion through the slider with constitute sliding connection between the slide rail of fixed plate, carry out spacingly to the direction of movement of rocking the portion.
Optionally, be equipped with the solid fixed ring that is used for putting the reaction cup on the support frame, gu fixed ring with the support frame detachable connection.
Optionally, the inside anticollision gasket that is equipped with of recess avoids causing the collision to the reaction cup.
As a second aspect of the present utility model, an immunoassay analyzer is disclosed, comprising the mixing structure.
The utility model has the beneficial effects that:
according to the utility model, the cleaning liquid and the magnetic beads in the reaction cup are uniformly mixed through the shaking part, after the mixing, the second driving unit is started to drive the eccentric wheel to rotate, the eccentric wheel rotates to drive the substrate to move downwards through the follow-up bearing, the substrate is separated from the cup bottom of the reaction cup, the cleaning liquid and the redundant objects to be detected are removed, after the completion, the reaction cup can be directly taken down from the fixing ring, and a new reaction cup is replaced, so that the reaction cup is convenient and quick.
Drawings
Fig. 1 is a first perspective view of a blending structure according to the present utility model.
Fig. 2 is a second perspective view of the mixing structure of the present utility model.
Fig. 3 is a plan view of a substrate of the mixing structure of the present utility model.
In the figure: 1. a shaking part; 11. a first driving unit; 12. a substrate; 13. a base; 131. a groove; 1311. an anti-collision gasket; 14. a slide block; 2. a support frame; 3. a fixing plate; 31. a slide rail; 4. a driving section; 41. a second driving unit; 42. an eccentric wheel; 43. and a follow-up bearing.
Detailed Description
The present utility model will be described in further detail with reference to the accompanying drawings.
As shown in fig. 1-3, the utility model discloses a mixing structure, which comprises a fixed plate 3, wherein a supporting frame 2 for placing a reaction cup is arranged on the fixed plate 3;
the device comprises a reaction cup, and is characterized by further comprising a shaking part 1 for shaking the reaction cup, wherein the shaking part 1 comprises a base plate 12, the base plate 12 is in sliding connection with the fixed plate 3, a first driving unit 11 is connected to the base plate 12, the first driving unit 11 is a driving motor, the output end of the first driving unit 11 is connected with a base 13, a groove 131 for placing the bottom of the reaction cup is arranged on the base 13, and the center of the groove 131 is arranged in a dislocation manner with the axis of an output shaft of the driving unit;
the fixed plate 3 is provided with a driving part 4 for driving the shaking part 1 to move up and down.
It should be noted that, since the outer side of the reaction cup is provided with the limiting edge, the reaction cup can be inserted into the supporting frame 2 to be limited and placed, the driving part 4 drives the shaking part 1 to rise, so that the groove 131 of the base 13 is attached to the bottom of the reaction cup upwards;
after the reaction cup is attached, the first driving unit 11 starts to drive the base 13 to rotate, and the groove 131 and the axis of the output shaft of the driving unit are arranged in a staggered mode, so that the cup bottom of the reaction cup is driven to eccentrically rotate, and the cup body of the reaction cup is limited by the support frame 2, so that the reaction cup is driven to shake, the cleaning liquid in the reaction cup generates vortex, the magnetic beads in the reaction cup move along with the vortex direction of the cleaning liquid, and the magnetic beads move up and down along with the vortex of the cleaning liquid and are fully mixed with the cleaning liquid uniformly;
after the mixture is fully mixed, the driving part 4 drives the shaking part 1 to descend, so that the base 13 is far away from the reaction cup, and the cleaning liquid and the redundant objects to be detected are sucked out by using the suction pipe.
As shown in fig. 1 and fig. 2, it should be noted that in this embodiment, the mixing structure further includes a follower bearing 43, the follower bearing 43 is detachably connected with the base plate 12, the driving portion 4 includes a second driving unit 41, the second driving unit 41 is a driving motor, the second driving unit 41 is detachably connected with the fixing plate 3, and an output end of the second driving unit is connected with an eccentric wheel 42 matched with the follower bearing 43;
it should be noted that, the second driving unit 41 is started to drive the eccentric wheel 42 to rotate, the eccentric wheel 42 is rotationally connected with the follower bearing 43, and the follower bearing 43 is detachably connected with the base plate 12, so that the eccentric wheel 42 rotates to drive the base plate 12 to move up and down through the follower bearing 43.
When the reaction cup rises to the corresponding position, the groove 131 of the base 13 is attached to the bottom of the reaction cup, and the reaction cup is uniformly shaken and mixed;
after being uniformly mixed, the base 13 is far away from the bottom of the reaction cup when being lowered to the corresponding position, and the cleaning liquid and the redundant objects to be tested are sucked out through the suction pipe, and the reaction cup is replaced.
As shown in fig. 1 and 2, in this embodiment, the fixing plate 3 is provided with a sliding rail 31, the shaking portion 1 further includes a sliding block 14 matched with the sliding rail 31, the sliding block 14 is detachably connected with the base plate 12, and the shaking portion 1 is slidably connected with the sliding rail 31 of the fixing plate 3 through the sliding block 14.
It should be noted that, since the base plate 12 is detachably connected with the slide block 14, and meanwhile, the slide block 14 is slidably connected with the slide rail 31, the base plate 12 is stably moved up and down by limiting the moving direction of the base plate 12 of the slide rail 31 during the up and down movement of the base plate 12.
In this embodiment, the support 2 is provided with a fixing ring for placing the reaction cup, and the fixing ring is detachably connected with the support 2.
It should be noted that a reserved opening is arranged on the support frame 2, and the fixing ring is in clamping connection with the support frame 2 through the reserved opening; when the fixing device is used, the fixing ring is inserted into the reserved opening of the support frame 2, the reaction cup is clamped on the fixing ring through the limiting edge, a certain gap is reserved between the reserved opening and the fixing ring, and between the fixing ring and the reaction cup, so that a certain shaking space is reserved for the reaction cup, and the reaction cup is prevented from being blocked in the shaking process.
As shown in fig. 3, in this embodiment, an anti-collision pad 1311 is disposed inside the recess 131; the reaction cup is prevented from being damaged when the groove 131 of the base 13 drives the cup bottom of the reaction cup to eccentrically rotate.
When the embodiment works, after the magnetic beads fully adsorb and detect an object to be detected in the reaction cup, cleaning liquid is injected into the reaction cup, the reaction cup is placed on the fixed ring, the second driving unit 41 is started to drive the eccentric wheel 42 to rotate, and the eccentric wheel 42 rotates to drive the follow-up bearing 43 and the substrate 12 to move upwards to corresponding positions at the same time, so that the groove 131 of the base 13 is attached to the bottom of the reaction cup upwards;
then the first driving unit 11 is started to drive the cup bottom of the reaction cup to eccentrically rotate, so that the cleaning liquid in the reaction cup generates vortex, the magnetic beads move along with the vortex direction of the cleaning liquid, and the magnetic beads move up and down along with the vortex direction of the cleaning liquid and are fully and uniformly mixed with the cleaning liquid;
after the mixing is completed, the second driving unit 41 drives the eccentric wheel 42 to rotate, the follow-up bearing 43 drives the base plate 12 to move downwards to the corresponding position, the base 13 is separated from the bottom of the reaction cup, and the cleaning liquid and the redundant objects to be detected are sucked out by the suction pipe, so that the work is completed.
The utility model also discloses an immunoassay analyzer, which comprises the mixing structure, wherein the mixing structure is detachably connected with the immunoassay analyzer through the fixing plate 3.
The foregoing is merely a preferred embodiment of the utility model, and it should be noted that modifications and enhancements can be made by those skilled in the art without departing from the principles of the present utility model. Such modifications and variations are also considered to be a departure from the scope of the utility model.
Claims (5)
1. The uniformly mixing structure is characterized by comprising a fixed plate, wherein a supporting frame for placing a reaction cup is arranged on the fixed plate;
the device comprises a reaction cup, a fixing plate, a first driving unit, a base, a groove, a first driving unit and a second driving unit, wherein the shaking part is used for shaking the reaction cup and comprises a base plate, the base plate is connected with the fixing plate in a sliding mode, the output end of the first driving unit is connected with the base, the base is provided with the groove for placing the bottom of the reaction cup, and the center of the groove is arranged in a dislocation mode with the axis of the output shaft of the driving unit;
the fixing plate is provided with a driving part for driving the shaking part to move up and down, the driving part comprises a second driving unit, and the second driving unit is detachably connected with the fixing plate;
the second driving unit is connected with the substrate, and the output end of the second driving unit is connected with an eccentric wheel matched with the follow-up bearing.
2. The mixing structure of claim 1, wherein the fixing plate is provided with a sliding rail, the shaking portion further comprises a sliding block matched with the sliding rail, the sliding block is detachably connected with the base plate, and the shaking portion is in sliding connection with the sliding rail of the fixing plate through the sliding block.
3. The mixing structure of claim 1, wherein the support frame is provided with a fixing ring for placing the reaction cup, and the fixing ring is detachably connected with the support frame.
4. The blending structure of claim 1, wherein an anti-collision gasket is disposed within the recess.
5. An immunoassay according to any one of claims 1 to 4, comprising a mixing structure.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321642666.8U CN220294598U (en) | 2023-06-26 | 2023-06-26 | Mixing structure and immunoassay appearance |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321642666.8U CN220294598U (en) | 2023-06-26 | 2023-06-26 | Mixing structure and immunoassay appearance |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220294598U true CN220294598U (en) | 2024-01-05 |
Family
ID=89374042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321642666.8U Active CN220294598U (en) | 2023-06-26 | 2023-06-26 | Mixing structure and immunoassay appearance |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220294598U (en) |
-
2023
- 2023-06-26 CN CN202321642666.8U patent/CN220294598U/en active Active
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