CN220293713U - Heart valve steady-state flow test system - Google Patents
Heart valve steady-state flow test system Download PDFInfo
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- CN220293713U CN220293713U CN202321651446.1U CN202321651446U CN220293713U CN 220293713 U CN220293713 U CN 220293713U CN 202321651446 U CN202321651446 U CN 202321651446U CN 220293713 U CN220293713 U CN 220293713U
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- 210000003709 heart valve Anatomy 0.000 title claims abstract description 99
- 238000012360 testing method Methods 0.000 title claims abstract description 96
- 239000012530 fluid Substances 0.000 claims abstract description 37
- 238000005086 pumping Methods 0.000 claims abstract description 30
- 230000008439 repair process Effects 0.000 claims abstract description 30
- 238000005259 measurement Methods 0.000 claims abstract description 18
- 239000007788 liquid Substances 0.000 claims abstract description 12
- 238000007789 sealing Methods 0.000 claims description 16
- 230000000694 effects Effects 0.000 claims description 11
- 238000000034 method Methods 0.000 claims description 6
- 206010067171 Regurgitation Diseases 0.000 claims description 5
- 210000003698 chordae tendineae Anatomy 0.000 claims description 5
- 210000003540 papillary muscle Anatomy 0.000 claims description 5
- 238000000605 extraction Methods 0.000 claims 1
- 238000013461 design Methods 0.000 abstract description 6
- 238000010992 reflux Methods 0.000 abstract description 6
- 238000009530 blood pressure measurement Methods 0.000 description 10
- 230000013011 mating Effects 0.000 description 7
- 238000010586 diagram Methods 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 230000008569 process Effects 0.000 description 4
- XECAHXYUAAWDEL-UHFFFAOYSA-N acrylonitrile butadiene styrene Chemical compound C=CC=C.C=CC#N.C=CC1=CC=CC=C1 XECAHXYUAAWDEL-UHFFFAOYSA-N 0.000 description 3
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 description 3
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 238000009434 installation Methods 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 206010067660 Heart valve incompetence Diseases 0.000 description 2
- 230000006978 adaptation Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000004088 simulation Methods 0.000 description 2
- 239000012085 test solution Substances 0.000 description 2
- 239000004793 Polystyrene Substances 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 210000001765 aortic valve Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- 238000013480 data collection Methods 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000003754 machining Methods 0.000 description 1
- 210000004115 mitral valve Anatomy 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 210000003102 pulmonary valve Anatomy 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 210000000591 tricuspid valve Anatomy 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
Classifications
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E30/00—Energy generation of nuclear origin
- Y02E30/30—Nuclear fission reactors
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- External Artificial Organs (AREA)
Abstract
The present application provides a heart valve steady-state flow testing system comprising: the measuring unit comprises a flow measuring module, a first differential pressure measuring module and a second differential pressure measuring module; the pumping module is used for pumping test liquid in the fluid storage module so as to enable the test liquid to flow through the isolated heart valve, the calibration standard nozzle and the flow measurement module in sequence and then return to the fluid storage module; the first differential pressure measuring module of the measuring unit is connected in parallel with two ends of the isolated heart valve, and the second differential pressure measuring module is connected in parallel with two ends of the calibration standard nozzle. The differential pressure and the reflux leakage of the standard nozzle can be tested, and the test data support close to reality is provided for valve repair instrument design.
Description
Technical Field
The application relates to the technical field of medical equipment, in particular to a heart valve steady-state flow testing system.
Background
When blood flows through a heart valve, a certain pressure difference across the valve is generated, and when the valve is closed, a certain amount of reflux leakage is caused, so that how to reasonably design the artificial heart valve needs to know the characteristics of the artificial heart valve in blood flow dynamics. In the prior art, two schemes of heart valve repair devices or replacement devices are often adopted for solving the problem of heart valve reflux leakage. The biggest difference between the former is that the prosthetic device acts on the native valve tissue, i.e. the leaflets or annulus are mechanically clamped on the basis of the native valve tissue, without replacing the native valve tissue. Therefore, it is important to measure how the effect of the prosthetic device in heart valve repair. In the prior art, a steady-state flow test system related to a heart valve repair instrument does not exist yet; and further, the repairing effect of the repairing instrument cannot be compared.
Disclosure of Invention
To overcome at least one of the problems in the related art, the present application provides a heart valve steady-state flow testing system.
The test system comprises:
the system of pipes is provided with a plurality of pipes,
the measuring unit comprises a flow measuring module, a first differential pressure measuring module and a second differential pressure measuring module;
the pumping module is used for pumping test liquid in the fluid storage module so as to enable the test liquid to flow through the isolated heart valve, the calibration standard nozzle and the flow measurement module in sequence and then return to the fluid storage module;
the first differential pressure measuring module of the measuring unit is connected in parallel with two ends of the isolated heart valve, and the second differential pressure measuring module is connected in parallel with two ends of the calibration standard nozzle.
In an alternative embodiment, a buffer device is further arranged on the pipeline between the pumping module and the isolated heart valve, and a plurality of through holes are arranged on the buffer device.
In an alternative embodiment, the isolated heart valve is connected in the pipeline system through a mounting bracket, two ends of the mounting bracket are respectively abutted with corresponding pipeline end faces, and the isolated heart valve is mounted in the mounting bracket.
In an alternative embodiment, the mounting bracket includes a first fixing seat and a second fixing seat, one of the first fixing seat and the second fixing seat is provided with an annular protrusion, the other one is provided with a groove matched with the annular protrusion, the isolated heart valve is mounted between the protrusion and the groove, and a fluid channel formed by the isolated heart valve extends along the pipeline system.
In an alternative embodiment, the first fixing seat and the second fixing seat are respectively provided with sealing rings on end faces facing the pipeline, and the sealing rings are used for sealing a gap between the mounting bracket and the pipeline.
In an alternative embodiment, the mounting bracket further comprises a first nut, a second nut, a third nut and a bolt, one end of the bolt passes through the through hole on the mounting bracket and is locked with the mounting bracket through the first nut, the second nut and the third nut are mounted at the other end of the bolt, and the second nut and the third nut are used for fixing papillary muscles and/or chordae tendineae of the isolated heart valve.
In an alternative embodiment, after completion of the ex vivo heart valve test, a repair device is mounted on the ex vivo heart valve to verify the repair effect of the repair device on regurgitation of the heart valve.
In an alternative embodiment, the pipeline system is provided with at least one evacuation module, and the evacuation module is connected with the air suction module to evacuate the gas in the pipeline system.
In an alternative embodiment, the evacuation module is switchable between an open state and a closed state, and is switched to the closed state after evacuation of gas within the piping system.
In an alternative embodiment, the test system further comprises a control module electrically connected to at least one of the pumping module, the flow measurement module, the first differential pressure measurement module, and the second differential pressure measurement module.
The technical scheme of the application has the following advantages or beneficial effects:
the pumping module is used for pumping test liquid in the fluid storage module, so that the test liquid flows through the isolated heart valve, the calibration standard nozzle and the flow measurement module in sequence and then returns to the fluid storage module; the first differential pressure measuring module of the measuring unit is connected in parallel with two ends of the isolated heart valve, and the second differential pressure measuring module is connected in parallel with two ends of the calibration standard nozzle; the structure enables the testing system of the application to synchronously measure the pressure difference and the backflow leakage of the isolated heart valve, and calibrate the pressure difference and the leakage flow of the standard nozzle; and calibrating the standard nozzle serves as a contrast by obtaining the differential pressure of the standard nozzle to calculate an acceptable precision tolerance. The data measurement of the calibration standard nozzle can ensure that the test data of the differential pressure and the backflow leakage quantity of the isolated heart valve are reasonable and reliable, and a test data support close to reality is provided for the valve repair instrument design.
A buffer device is arranged on a pipeline between the pumping module and the isolated heart valve, and a plurality of through holes are arranged on the buffer device; the uniformity of the fluid in the pipeline can be improved, so that the simulation effect is more fit with the actual blood flow process, and the measured reflux leakage quantity and the measured differential pressure data are more fit with the actual situation.
The mounting bracket comprises a first fixing seat and a second fixing seat, one of the first fixing seat and the second fixing seat is provided with an annular bulge, the other one of the first fixing seat and the second fixing seat is provided with a groove matched with the annular bulge, and the isolated heart valve is mounted between the bulge and the groove; the groove and the bulge structure enable the isolated heart valve to be firmly fixed on the mounting bracket, and even if the repaired instrument is acted by external force, the repaired instrument can be kept on the mounting bracket and not carried out; the complex mating surface formed by the concave-convex structure ensures tightness, so that the test solution cannot leak out from the mating surface between the first fixing seat and the second fixing seat.
The isolated heart valve can be further provided with a repair instrument, after the instrument installation is completed, the isolated heart valve is installed in the installation bracket, then the assembly is installed in the pipeline system, and the pumping module is started to simulate the reflux leakage of the heart valve so as to verify whether the designed repair instrument meets the use requirement; thereby providing ideal test conditions for the design of the repairing apparatus and improving the reliability of the design of the repairing apparatus.
Drawings
The drawings are included to provide a better understanding of the present application and are not to be construed as unduly limiting the present application. Wherein:
FIG. 1 is a schematic diagram of a heart valve steady-state flow testing system according to an embodiment of the present application;
FIG. 2 is an exploded schematic view of a heart valve mounting bracket according to an embodiment of the present application;
FIG. 3 is a schematic view of a heart valve mounted to a mounting bracket according to an embodiment of the present application;
FIG. 4 is a schematic diagram of a water pump according to an embodiment of the present application;
FIG. 5 is a schematic diagram of a piping structure of a piping system according to an embodiment of the present application;
FIG. 6 is a schematic structural view of a flow measurement module according to an embodiment of the present application;
FIG. 7 is a schematic illustration of a fluid storage module configuration according to an embodiment of the present application;
FIG. 8 is a schematic diagram of a buffer module according to an embodiment of the present application;
FIG. 9 is a schematic view in longitudinal section of a buffer module according to an embodiment of the present application;
FIG. 10 is an assembled schematic view of an evacuation module and a differential pressure measurement module according to an embodiment of the present application;
FIG. 11 is a schematic view of the structure of a calibration standard nozzle according to an embodiment of the present application;
FIG. 12 is a schematic cross-sectional view of the A-A position of a calibration standard nozzle according to an embodiment of the present application;
FIG. 13 is a schematic structural view of an evacuation module according to an embodiment of the present application;
FIG. 14 is a schematic illustration of an evacuation process according to an embodiment of the present application;
FIG. 15 is an evacuation complete schematic according to an embodiment of the present application;
FIG. 16 is an exploded schematic view of a prosthetic device mounted to a heart valve according to an embodiment of the present application;
FIG. 17 is a physical connection schematic of a test system according to an embodiment of the present application;
FIG. 18 is a schematic partial cross-sectional view of a physical connection of a test system according to an embodiment of the present application.
Detailed Description
Exemplary embodiments of the present application are described below in conjunction with the accompanying drawings, which include various details of the embodiments of the present application to facilitate understanding, and should be considered as merely exemplary. Accordingly, one of ordinary skill in the art will recognize that various changes and modifications of the embodiments described herein can be made without departing from the scope and spirit of the present application. Also, descriptions of well-known functions and constructions are omitted in the following description for clarity and conciseness.
The terminology used in the present application is for the purpose of describing particular embodiments only and is not intended to be limiting of the present application. As used in this application and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It should also be understood that the term "and/or" as used herein refers to and encompasses any or all possible combinations of one or more of the associated listed items.
It should be understood that although the terms first, second, third, etc. may be used herein to describe various information, these information should not be limited by these terms. These terms are only used to distinguish one type of information from another. For example, a first message may also be referred to as a second message, and similarly, a second message may also be referred to as a first message, without departing from the scope of the present application. The word "if" as used herein may be interpreted as "at … …" or "at … …" or "responsive to a determination", depending on the context.
Heart valve regurgitation leakage is one of the major disorders of heart disease. In the prior art, two modes of valve replacement and valve repair are commonly adopted for treatment. In the latter case, how to determine the heart valve regurgitation parameters and how to evaluate the effect of repair after implantation of the repair instrument is a key indicator that the designer needs to consider. Thus, how to systematically and accurately evaluate the regurgitant leakage amount of a heart valve and the repair effect of a repair instrument is a core problem to be solved by the present application. To this end, the present application proposes a heart valve steady-state flow testing system comprising: the system comprises a pipeline system and a measuring unit, wherein the measuring unit comprises a flow measuring module, a first differential pressure measuring module and a second differential pressure measuring module; the pumping module is used for pumping test liquid in the fluid storage module so as to enable the test liquid to flow through the isolated heart valve, the calibration standard nozzle and the flow measurement module in sequence and then return to the fluid storage module; the first differential pressure measuring module of the measuring unit is connected in parallel with two ends of the isolated heart valve, and the second differential pressure measuring module is connected in parallel with two ends of the calibration standard nozzle.
In the embodiment shown in fig. 1, a heart valve steady-state flow testing system is illustratively shown. The test system mainly comprises a pipeline system and a measuring unit. The measuring unit comprises a flow measuring module, a first differential pressure measuring module and a second differential pressure measuring module. The flow measuring module is used for measuring the flow in the pipeline system in the valve regurgitation state, and the flow is used for reflecting the leakage quantity flowing through the isolated valve in the regurgitation state. The flow measurement module may be a flowmeter, for example, and is merely exemplary, and is not intended to limit the scope of the present application. The first differential pressure measuring module and the second differential pressure measuring module are used for measuring the differential pressure of fluid at the upstream and downstream of the element to be measured. As shown in fig. 1, the pipe system is formed by splicing a plurality of test channels (or called pipes), and a flange end surface is arranged on the end surface of each test pipe so as to be connected with each other or other elements. Specifically, in the example shown in fig. 1, the pipe system includes a test channel No. 1 104, a test channel No. 2 105, a test channel No. 3 106, a test channel No. 4 107, a test channel No. 5 108, a test channel No. 4 107, a test channel No. 6 111, and a test channel No. 7 112, which are connected in sequence. In addition, the pumping module 101, the isolated heart valve 205, the calibration standard nozzle 115, the flow measurement module 114 and the fluid storage module 113 are connected in series in the pipeline system. The serial connection means that the elements are connected in series through a pipeline or a test channel. In operation, the pumping module 101 draws and pumps the test liquid from the fluid storage module 113 to flow the test liquid sequentially through the isolated heart valve, the calibrated standard nozzle, and the flow measurement module and back to the fluid storage module. In practice, the pumping module 101 may be selected as a water pump, which is only a name for pumping various fluids, not just water, such as the test fluids used in the test of the present application. Fig. 4 illustrates a conventional water pump 301 having two ports, each having a conduit 302 and a conduit 303 connected thereto, wherein the conduit 302 is connected to the fluid storage module described above and the conduit 303 is connected to the test channel No. 1. The isolated heart valve may be an animal heart valve. The fluid storage module 113 may optionally be a reservoir. The reservoir may take a variety of configurations, such as the rectangular parallelepiped configuration shown in fig. 7. In the embodiments shown in fig. 1, 17 and 18, the backflow flow process of the ex-vivo heart valve may be simulated after the fluid pumped by the pumping module enters the ex-vivo heart valve. The calibration standard nozzle is used to calculate acceptable precision tolerances that are required for use with flow measurement modules and differential pressure measurement modules, as described in detail below. The first differential pressure measuring module 118 of the measuring unit is connected in parallel to two ends of the isolated heart valve, and the second differential pressure measuring module 116 is connected in parallel to two ends of the calibration standard nozzle. The back flow leakage of the isolated heart valve and the flow through the calibrated standard nozzle are monitored by installing a flow measurement module within the tubing. The first differential pressure measuring unit is used for measuring the differential pressure of the test fluid crossing the front and the rear of the isolated heart valve, and the differential pressure reflects the differential pressure of the front and the rear of the isolated heart valve; the second differential pressure measuring unit is used for measuring the differential pressure of the test fluid which spans the front and the rear of the standard calibrating nozzle, and the differential pressure reflects the differential pressure of the front and the rear of the standard calibrating nozzle. In the example shown in fig. 5 and 10, an assembly diagram of the differential pressure measurement unit is shown. Wherein, a differential pressure connecting hole 402 is arranged on the pipeline of the pipeline system, a differential pressure connector 1004 is installed in the differential pressure connecting hole 402, the other connector of the differential pressure connector 1004 is used for connecting a differential pressure measuring unit, and the differential pressure measuring unit can be a pressure sensor 1003. In one implementation, in order to reduce the difficulty of machining the pipeline, through holes formed in the pipeline of the pipeline system are used for connecting the evacuation module, and the differential pressure measurement unit is connected through an interface on the evacuation module. The method not only reduces the processing difficulty of the pipeline, but also is convenient for flexibly adjusting the number of the emptying modules in the emptying process, and is more convenient for the connection of the differential pressure measuring unit. In the embodiment shown in fig. 11 and 12, the calibration standard nozzle is in a disc structure, and a through hole is formed in the center of the disc structure; and the through hole has a tapered structure, namely the sectional area of the fluid inlet is larger than that of the fluid outlet, so that the fluid is sprayed out in a spraying state after flowing through the calibrated standard nozzle for acceleration. By the test system, the pressure difference and the backflow leakage quantity of the isolated heart valve, and the pressure difference and the leakage flow quantity of the calibrated standard nozzle can be synchronously measured. It should be noted that the calibration standard nozzle serves as a contrast, and the acceptable precision tolerance is calculated by obtaining the differential pressure of the standard nozzle. Further, by obtaining a pressure-leakage curve of the calibration standard nozzle and comparing the curve with the gradient of the industry standard backflow nozzle, whether the test data are reasonable and reliable is judged, so that the reasonable and reliable test data of the pressure difference and the backflow leakage of the isolated heart valve are ensured. Therefore, the technical scheme disclosed by the embodiment of the application not only can measure the data of the isolated heart valve, but also can monitor the reliability of the measured data, and provides a test data support close to reality for the design of the valve repair instrument.
In an alternative embodiment, a buffer device is further arranged on the pipeline between the pumping module and the isolated heart valve, and a plurality of through holes are arranged on the buffer device. In the example shown in fig. 1, 8 and 9, a buffer 102 is also connected between the pumping module and the ex-vivo heart valve. The damper 102 includes a pipe portion 801 and a through hole 802 provided in the pipe portion 801, the through hole 802 extending along an axis of the damper 102 and forming a flow passage therethrough. In one embodiment, the plurality of through holes 802 are uniformly distributed along the end surface of the pipe 801. In use, because the pressure of the fluid pumped by the pumping device is higher, and the distribution of the flow rate, the pressure and the like along the pipeline is uneven, if the fluid pumped by the pumping device is directly sent to the isolated heart valve, the uneven distribution of the fluid pressure received by the isolated heart valve can be caused, and the accuracy of the measurement result is affected. Therefore, after the buffer device is arranged, the flow speed and the pressure difference of the fluid after passing through the through holes are reduced, and the flow speed and the pressure of the outlet ends of the through holes are basically equal, and the water flow is more linear, so that the simulation result of the test system is more consistent with the actual situation.
In an alternative embodiment, the isolated heart valve is connected in the pipeline system through a mounting bracket, two ends of the mounting bracket are respectively abutted with corresponding pipeline end faces, and the isolated heart valve is mounted in the mounting bracket. In the embodiment shown in fig. 1 and 3, the illustrated ex-vivo heart valve 205 is attached to the conduit by a mounting bracket 103. Since the ex-vivo heart valve has a certain flexibility, it is difficult to mount directly on the connection end face of the tube, for example, it is difficult to directly connect to the mating face between the test tube No. 2 105 and the test tube No. 3 106 shown in fig. 1. Furthermore, even if it is forcibly attached to the above-mentioned mating surface, there is more or less leakage of fluid, which affects the safety of the test device and the accuracy of measurement. To this end, in one embodiment of the present application, a mounting bracket is provided as shown in fig. 2 and 3, the mounting bracket providing structure for holding or securing the isolated heart valve, and the combination of the two can be mounted on the mating surface when the isolated heart valve is mounted on the mounting bracket. It will be appreciated that the mounting bracket may be pre-configured with a connection interface that mates with the end face of the test tube.
In an alternative embodiment, the mounting bracket includes a first fixing seat and a second fixing seat, one of the first fixing seat and the second fixing seat is provided with an annular protrusion, the other one is provided with a groove matched with the annular protrusion, the isolated heart valve is mounted between the protrusion and the groove, and a fluid channel formed by the isolated heart valve extends along the pipeline system. In the embodiment shown in fig. 2 and 3, the mounting bracket includes a first fixing base 202 and a second fixing base 204, and the two fixing bases may be made of acrylonitrile-butadiene-styrene (Acrylonitrile Butadiene Styrene, ABS), polycarbonate (PC), polystyrene (PS), and the like. The end faces of the first fixing seat and the second fixing seat, which are opposite, are provided with annular protrusions and annular grooves, and when the first fixing seat and the second fixing seat are assembled together, the protrusions and the grooves can be clamped together. When assembling the isolated heart valve, the edges of the valve may be crimped between the protrusions and the grooves. The groove and the bulge structure enable the isolated heart valve to be firmly fixed on the mounting bracket, and even the repaired instrument can be kept on the mounting bracket and not carried out after being acted by external force. For this reason, when later verifying the repair effect of the repair device, the operator can easily mount the repair device on the isolated heart valve, regardless of whether the heart valve is detached from between the mountings. Furthermore, the complex mating surface formed by the concave-convex structure ensures the tightness, so that the test solution cannot leak out from the mating surface between the first fixing seat and the second fixing seat. After the isolated heart valve is clamped on the mounting bracket, the flow passage formed by the isolated heart valve extends along the fluid flow direction 109 of the pipeline, so that the fluid pumped by the pumping module can be ensured to be reversely sent into the isolated heart valve to simulate the phenomenon of backflow leakage. In the test, the isolated heart valve may be a tricuspid valve, mitral valve, aortic valve, pulmonary valve, etc.
In an alternative embodiment, the first fixing seat and the second fixing seat are respectively provided with sealing rings on end faces facing the pipeline, and the sealing rings are used for sealing a gap between the mounting bracket and the pipeline. In the embodiment shown in fig. 2, the parts of the first fixing seat and the second fixing seat facing the end face of the pipeline are respectively provided with a sealing element mounting part, and the sealing elements can be a left sealing ring 201 and a right sealing ring 203. When the mounting bracket and the pipeline are matched and mounted, the end face of the pipeline and the mounting bracket jointly squeeze the sealing element and deform the sealing element to generate a sealing effect.
In an alternative embodiment, the mounting bracket further comprises a first nut, a second nut, a third nut and a bolt, one end of the bolt passes through the through hole on the mounting bracket and is locked with the mounting bracket through the first nut, the second nut and the third nut are mounted at the other end of the bolt, and the second nut and the third nut are used for fixing papillary muscles and/or chordae tendineae of the isolated heart valve. In the embodiment shown in fig. 3, the mounting bracket further includes a plurality of nuts and bolts 211, wherein the nuts include a first nut 206, a second nut 207, and a third nut 209. The bolts and the nuts comprise three groups, one bolt in each group is provided with the first nut, the second nut and the third nut, and the second nut and the third nut are positioned at the end part of the screw far away from the main body of the mounting bracket. The second and third nuts are spaced apart and are used to secure papillary muscles and/or chordae tendineae 210 of the isolated heart valve. In particular, the papillary muscles and/or chordae tendineae may be stuffed at the gap between the first nut and the second nut and then secured within the gap with a securing element. As shown in fig. 3, a tie 208 is used to secure it. The other end of the screw is secured to the mounting bracket by a first nut 206. Specifically, three through holes may be provided in the mounting bracket, and after the bolts are inserted into the through holes, the screw and the mounting bracket are locked together by the first nuts 206.
In an alternative embodiment, after completion of the ex vivo heart valve test, a repair device is mounted on the ex vivo heart valve to verify the repair effect of the repair device on regurgitation of the heart valve. As shown in fig. 16, a repair device 1601 may be further installed on the isolated heart valve, after the device is installed, the isolated heart valve is installed in the installation support, and then the assembly is installed in the pipeline system, and the pumping module is started to simulate the reflux leakage of the heart valve, so as to verify whether the designed repair device meets the use requirement. In a specific operation, the repair effect of the isolated heart valve can also be confirmed by collecting test data of the isolated heart valve after the repair instrument is installed, such as pressure difference and leakage amount data, and comparing the test data with the test data without the repair instrument.
In an alternative embodiment, the pipeline system is provided with at least one evacuation module, and the evacuation module is connected with the air suction module to evacuate the gas in the pipeline system. In an alternative embodiment, the evacuation module is switchable between an open state and a closed state, and is switched to the closed state after evacuation of gas within the piping system. In practice, in order to minimize the flow of blood, it is necessary to empty the tubing of the gas before starting the test device. In particular, an evacuation module may be provided on the piping system. It will be appreciated that when a plurality of evacuation modules are provided, evacuation may be performed for the tubing from different locations, improving the efficiency of the evacuation operation. In the embodiment shown in fig. 17, each pipe in the pipe system is provided with an evacuation connection hole, and the evacuation connection hole is connected with a corresponding evacuation module. As shown in fig. 5 and 10, it is illustrated how an evacuation valve connection hole 401 is provided in the pipe to perform an evacuation operation on the length of pipe. Specifically, an evacuation module such as an evacuation valve 1002 may be mounted on the connection hole 401, and then the evacuation module is connected at the connection port of the evacuation module. In one embodiment, a syringe is used to evacuate the gas from the tubing. For example, referring to the embodiment shown in fig. 14 and 15, after the syringe 1001 is connected to the port 1402 of the evacuation module, and the operating handle 1403 (or OFF flag) of the evacuation module is placed in an open position as shown in fig. 14 in an upright position, the plunger 1401 of the syringe is then pulled to drive fluid flow within the tubing, and the gas 1405 will exit the tubing and enter the injection session as the plunger moves. If there is more gas in the pipe, the above operation may be repeatedly performed until the gas in the pipe is exhausted. After the evacuation operation is completed, the operating handle of the evacuation module may be placed in a closed state, such as the horizontal state shown in fig. 15.
In an alternative embodiment, the test system further comprises a control module electrically connected to at least one of the pumping module, the flow measurement module, the first differential pressure measurement module, and the second differential pressure measurement module. In order to improve the automation degree of the test system and collect and store corresponding data in real time so as to perform various data analyses, in one example, a control module 1701 is further integrated in the test system, and the control module may be provided with a data collection card to collect data measured by various measurement modules, for example, the control module is respectively connected with the flow measurement module, the first differential pressure measurement module and the second differential pressure measurement module to collect flow and differential pressure data in real time; alternatively, the control module may be electrically connected to the pumping module to remotely control the pumping module to be remotely turned on or off.
The above embodiments do not limit the scope of the application. Other embodiments of the disclosure will be apparent to those skilled in the art from consideration of the specification and practice of the disclosed subject matter. This application is intended to cover any adaptations, uses, or adaptations of the disclosure following, in general, the principles of the disclosure and including such departures from the present disclosure as come within known or customary practice within the art to which the disclosure pertains. It is intended that the specification and examples be considered as exemplary only, with a true scope and spirit of the disclosure being indicated by the following claims.
It is to be understood that the present disclosure is not limited to the precise arrangements and instrumentalities shown in the drawings, and that various modifications and changes may be effected without departing from the scope thereof. The scope of the present disclosure is limited only by the appended claims.
Claims (10)
1. A heart valve steady-state flow testing system, comprising:
the system of pipes is provided with a plurality of pipes,
the measuring unit comprises a flow measuring module, a first differential pressure measuring module and a second differential pressure measuring module;
the method is characterized in that:
the pumping module is used for pumping test liquid in the fluid storage module so as to enable the test liquid to flow through the isolated heart valve, the calibration standard nozzle and the flow measurement module in sequence and then return to the fluid storage module;
the first differential pressure measuring module of the measuring unit is connected in parallel with two ends of the isolated heart valve, and the second differential pressure measuring module is connected in parallel with two ends of the calibration standard nozzle.
2. The test system of claim 1, wherein the test system comprises a plurality of test cells,
and a buffer device is further arranged on the pipeline between the pumping module and the isolated heart valve, and a plurality of through holes are formed in the buffer device.
3. The test system of claim 1, wherein the test system comprises a plurality of test cells,
the isolated heart valve is connected in the pipeline system through the mounting bracket, two ends of the mounting bracket are respectively abutted with the corresponding end faces of the pipeline, and the isolated heart valve is mounted in the mounting bracket.
4. The test system of claim 3, wherein the test system comprises a plurality of test cells,
the mounting bracket comprises a first fixing seat and a second fixing seat, one of the first fixing seat and the second fixing seat is provided with an annular bulge, the other one of the first fixing seat and the second fixing seat is provided with a groove matched with the annular bulge, the isolated heart valve is mounted between the bulge and the groove, and a fluid channel formed by the isolated heart valve extends along the pipeline system.
5. The test system of claim 4, wherein the test system comprises a plurality of test cells,
the first fixing seat and the second fixing seat are respectively provided with sealing rings on the end faces facing the pipeline, and the sealing rings are used for sealing gaps between the mounting support and the pipeline.
6. The test system of claim 3, wherein the test system comprises a plurality of test cells,
the mounting bracket further comprises a first nut, a second nut, a third nut and a bolt, one end of the bolt penetrates through the through hole in the mounting bracket and is locked with the mounting bracket through the first nut, the second nut and the third nut are mounted at the other end of the bolt, and the second nut and the third nut are used for fixing papillary muscles and/or chordae tendineae of the isolated heart valve.
7. The test system of claim 1, wherein the test system comprises a plurality of test cells,
after the completion of the ex vivo heart valve test, a repair instrument is mounted on the ex vivo heart valve to verify the repair effect of the repair instrument on regurgitation of the heart valve.
8. The test system of claim 1, wherein the test system comprises a plurality of test cells,
the pipeline system is provided with at least one evacuation module, and the evacuation module is connected with the air extraction module to evacuate the gas in the pipeline system.
9. The test system of claim 8, wherein the test system comprises a plurality of test cells,
the evacuation module is switchable between an open state and a closed state, and is switched to the closed state after the gas in the pipeline system is evacuated.
10. The test system of claim 1, wherein the test system comprises a plurality of test cells,
the test system further comprises a control module electrically connected with at least one of the pumping module, the flow measuring module, the first differential pressure measuring module and the second differential pressure measuring module.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310145512.6A CN115919509A (en) | 2023-02-22 | 2023-02-22 | Heart valve steady-state flow testing system |
| CN2023101455126 | 2023-02-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220293713U true CN220293713U (en) | 2024-01-05 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310145512.6A Pending CN115919509A (en) | 2023-02-22 | 2023-02-22 | Heart valve steady-state flow testing system |
| CN202321651446.1U Active CN220293713U (en) | 2023-02-22 | 2023-06-28 | Heart valve steady-state flow test system |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310145512.6A Pending CN115919509A (en) | 2023-02-22 | 2023-02-22 | Heart valve steady-state flow testing system |
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Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE513516T1 (en) * | 2005-01-21 | 2011-07-15 | Mayo Foundation | THORASCOPIC HEART VALVE REPAIR DEVICE |
| CA2703129C (en) * | 2007-10-18 | 2016-02-16 | Neochord Inc. | Minimially invasive repair of a valve leaflet in a beating heart |
| CN111437069A (en) * | 2020-04-26 | 2020-07-24 | 科凯(南通)生命科学有限公司 | Heart valve flow performance detection device |
| CN114533346A (en) * | 2022-02-15 | 2022-05-27 | 上海盈阁智能科技有限公司 | Valve steady-state flow performance testing system and method |
-
2023
- 2023-02-22 CN CN202310145512.6A patent/CN115919509A/en active Pending
- 2023-06-28 CN CN202321651446.1U patent/CN220293713U/en active Active
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| CN115919509A (en) | 2023-04-07 |
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