CN220207240U

CN220207240U - Chylomicron separator

Info

Publication number: CN220207240U
Application number: CN202321460801.7U
Authority: CN
Inventors: 张宁; 许鑫; 王晓琴
Original assignee: First Affiliated Hospital of Medical College of Xian Jiaotong University
Current assignee: First Affiliated Hospital of Medical College of Xian Jiaotong University
Priority date: 2023-06-09
Filing date: 2023-06-09
Publication date: 2023-12-19
Anticipated expiration: 2033-06-09

Abstract

The utility model provides a chylomicron separating device, which comprises an outer sleeve, wherein a separating mechanism is arranged in the outer sleeve and comprises an inner sleeve, the bottom of the inner sleeve is connected with a first filter screen, the outer side of the inner sleeve is connected with a limiting ring, the limiting ring is arranged in the outer sleeve, limiting grooves are formed in two sides of the top of the outer sleeve, and the outer side of the limiting ring is clamped and matched with the inner part of the limiting grooves. The chylomicron separation device provided by the utility model solves the problems that chemical reagents added in a chemical method interfere with biochemical reaction, in a physical method, the dilution method also dilutes the content of a substance to be detected while eliminating chylomicron interference, so that the detection accuracy is reduced, the low-temperature refrigeration method is not suitable for the requirement of rapid detection of patients, the chylomicron can be rapidly separated by a high-speed centrifugation method, but the separated chylomicron still exists on the upper layer of a sample to be detected, and the chylomicron cannot be directly used for laboratory detection, and the detection result has deviation.

Description

Chylomicron separator

Technical Field

The utility model relates to the field of medical appliances, in particular to a chylomicron separation device.

Background

For chyle sample patients, interference factors cannot be removed through re-bleeding, and in most cases, the patients are emergency critical admission, quick and reliable test results are needed, and the test is needed to be yielded to meet clinical diagnosis and treatment requirements, so that the chyle samples are required to be quickly preprocessed, the influence of interference factors such as chyle particles on the test results is eliminated, the clinical test requirements are met, and the influence of unqualified samples on the test results is reduced to the greatest extent.

Based on interference mechanisms of chyle samples, the conventional methods for eliminating chyle particles comprise a physical method and a chemical method, wherein the physical method and the chemical method comprise a physiological saline dilution method, a high-speed centrifugation method, a freezing high-speed centrifugation method, a vacuum high-speed centrifugation method, a low-temperature refrigeration method, a phosphotungstic acid-magnesium method, a polyethylene glycol method, an ether extraction method, a lipid scavenger and the like, but the methods have defects of different degrees in clinical use, chemical reagents added in the chemical method interfere biochemical reaction, the dilution method also dilutes the content of substances to be detected while eliminating chyle particle interference in the physical method, so that the detection accuracy is reduced, the low-temperature refrigeration method is not suitable for the requirement of rapid detection of patients, the high-speed centrifugation method can rapidly separate chyle particles, but the separated chyle particles still exist on the upper layer of the samples to be detected in a laboratory and cannot be directly used for detection, and the problem of deviation of detection results can be caused.

Accordingly, there is a need to provide a new chylomicron separation device that solves the above-mentioned technical problems.

Disclosure of Invention

In order to solve the technical problems, the utility model provides a chylomicron separating device which has high practicability and is convenient to use.

The utility model provides a chyle particle separating device, which comprises an outer sleeve, wherein a separating mechanism is arranged in the outer sleeve and comprises an inner sleeve, the bottom of the inner sleeve is connected with a first filter screen, the outer side of the inner sleeve is connected with a limiting ring, and the limiting ring is arranged in the outer sleeve.

In order to achieve the effect of improving the clamping stability of the inner sleeve, the utility model provides the chylomicron separating device, preferably, both sides of the top of the outer sleeve are provided with limiting grooves, and the outer side of the limiting ring is matched with the inner part of the limiting grooves in a clamping way.

In order to achieve the effect of clamping the limiting ring, the chylomicron separating device provided by the utility model is preferable in that the bottom of the limiting ring is provided with a clamping groove, and the top of the outer sleeve is clamped in the clamping groove.

In order to achieve the effect of improving the sealing performance and the stability, as the chylomicron separating device provided by the utility model, preferably, an annular groove is formed on the outer side of the bottom of the inner sleeve, and a sealing ring is arranged in the annular groove.

In order to achieve the effect of improving the filtering, as the chylomicron separating device provided by the utility model, preferably, the bottom of the inner sleeve is connected with the contraction ring, the bottom of the first filter screen is provided with the second filter screen, and the outer side of the second filter screen is connected with the inner part of the contraction ring.

Compared with the prior art, the utility model has the beneficial effects that:

according to the chylomicron separation device, the inner sleeve is arranged in the outer sleeve, operation of a clinical laboratory worker is facilitated, only a serum or plasma sample containing chylomicron is required to be sucked into the inner sleeve of the separation device through the suction pipe, the inner sleeve is fixed on the top pipe of the outer sleeve, the inner sleeve is sealed and placed in the high-speed centrifugal machine, under the action of high-speed centrifugal force, the detected serum or plasma is stored at the bottom end of the outer sleeve through the filter screen, particulate matters such as chylomicron and the like remain in the filter screen of the inner sleeve, chylomicron separation can be completed by removing the inner sleeve, the operation is simple and convenient, the quality of a sample to be detected is greatly improved, the problem that the chemical reagent added in the traditional chemical method interferes with biochemical reaction is solved, the dilution method dilutes the content of the substance to be detected while eliminating the interference of the chylomicron, so that the detection accuracy is reduced, the low-temperature refrigeration method is not suitable for the requirement of rapid detection of a patient, the high-speed centrifugal method can rapidly separate chylomicron still exist on the upper layer of the sample to be detected, and the problem that deviation exists in the detection result cannot be caused.

Drawings

Fig. 1 is a schematic structural view of a preferred embodiment of a chylomicron separation device according to the present utility model;

FIG. 2 is a schematic view of the outer sleeve of FIG. 1;

FIG. 3 is a schematic view of the inner sleeve of FIG. 1;

fig. 4 is a structural cross-sectional view of the inner sleeve shown in fig. 3.

Reference numerals in the drawings: 1. an outer sleeve; 2. a separation mechanism; 21. an inner sleeve; 22. a limiting ring; 23. a first filter screen; 3. a limit groove; 4. a clamping groove; 5. a seal ring; 6. a shrink ring; 7. a second filter screen; 8. an annular groove.

Detailed Description

The utility model will be further described with reference to the drawings and embodiments.

Referring to fig. 1, fig. 2, fig. 3 and fig. 4 in combination, fig. 1 is a schematic structural view of a chylomicron separating apparatus according to a preferred embodiment of the present utility model; FIG. 2 is a schematic view of the outer sleeve of FIG. 1; FIG. 3 is a schematic view of the inner sleeve of FIG. 1; fig. 4 is a structural cross-sectional view of the inner sleeve shown in fig. 3. The chylomicron separating device comprises an outer sleeve 1, a separating mechanism 2 is arranged in the outer sleeve 1, the separating mechanism 2 comprises an inner sleeve 21, a first filter screen 23 is connected to the bottom of the inner sleeve 21, a limiting ring 22 is connected to the outer side of the inner sleeve 21, and the limiting ring 22 is arranged in the outer sleeve 1.

In the specific implementation process, as shown in fig. 1, 2, 3 and 4, the two sides of the top of the outer sleeve 1 are both provided with a limit groove 3, and the outer side of the limit ring 22 is in clamping fit with the inside of the limit groove 3.

Referring to fig. 1, 2, 3 and 4, a clamping groove 4 is formed at the bottom of the limiting ring 22, and the top of the outer sleeve 1 is clamped in the clamping groove 4.

Referring to fig. 1, 2, 3 and 4, an annular groove 8 is formed on the outer side of the bottom of the inner sleeve 21, and a sealing ring 5 is arranged in the annular groove 8.

Referring to fig. 1, 2, 3 and 4, the bottom of the inner sleeve 21 is connected with a shrink ring 6, the bottom of the first filter screen 23 is provided with a second filter screen 7, and the outer side of the second filter screen 7 is connected with the inside of the shrink ring 6.

It should be noted that: the length of interior sleeve pipe 21 is half of outer tube 1, liquid and chylomicron after being convenient for centrifuge separates, prevent interior sleeve pipe 21 length and outer tube 1 from being close, the condition of separating, first filter screen 23 has 50 mesh respectively, 100 mesh, 200 mesh, second filter screen 7 is higher than first filter screen 23 filter fineness, and the top of shrink ring 6 and the bottom of interior sleeve pipe 21 an organic whole of moulding plastics in interior sleeve pipe 21 bottom draw-in groove 4 are firmly fixed, through setting up shrink ring 6, the movable range of the serum and the plasma sample of the shrink chylomicron of being convenient for, the inside of spacing ring 22 and the outside of interior sleeve pipe 21 mould plastics an organic whole, the inside of interior sleeve pipe 21 is inlayed to first filter screen 23, the inside of shrink ring 6 is inlayed to second filter screen 7.

The working principle of the chyle particle separating device provided by the utility model is as follows:

when in use, the inner sleeve 21 is inserted into the outer sleeve 1, so that the limiting ring 22 and the clamping groove 4 at the outer side of the inner sleeve 21 are clamped in the limiting groove 3 at the outer side of the outer sleeve 1, when the inner sleeve 21 enters the outer sleeve 1, the sealing ring 5 at the outer side of the inner sleeve 21 can be attached to the inner wall of the outer sleeve 1 to prevent blood from adhering to the outer side of the inner sleeve 21 through gaps, then the serum or plasma sample containing chylomicron is sucked into the inner sleeve 21 by a suction pipe, the inner sleeve 21 is fixed on the top pipe of the outer sleeve 1, the inner sleeve 21 is hermetically placed in a high-speed centrifuge, under the action of high-speed centrifugal force, the serum or plasma for detection is stored at the bottom end of the outer sleeve 1 through the first filter screen 23, the second filter screen 7 is arranged at the bottom of the first filter screen 23, prevent that first filter screen 23's filter fineness is lower, chylomicron spills the inside that drops outer tube 1 from the through-hole, second filter screen 7's filter fineness is higher than first filter screen 23's filter fineness, be convenient for filter the chylomicron that first filter screen 23 filtered, particulate matter such as chylomicron remains in interior sleeve 21 first filter screen 23 and second filter screen 7, remove interior sleeve 21 and can accomplish chylomicron separation, easy and simple to handle, sample quality to be examined has been improved greatly, the centrifuge stops rotating the back, take out outer tube 1, then through stirring spacing ring 22, make spacing ring 22 drive interior sleeve 21 and outer tube 1 separation, then throw interior sleeve 21 into medical waste with concentrated processing can.

The foregoing description is only illustrative of the present utility model and is not intended to limit the scope of the utility model, and all equivalent structures or equivalent processes or direct or indirect application in other related technical fields are included in the scope of the present utility model.

Claims

1. Chylomicron separator, its characterized in that includes outer tube (1), the inside of outer tube (1) is provided with separating mechanism (2), separating mechanism (2) include interior sleeve pipe (21), the bottom of interior sleeve pipe (21) is connected with first filter screen (23), the outside of interior sleeve pipe (21) is connected with spacing ring (22), spacing ring (22) are seted up in the inside of outer tube (1).

2. The chyle particle separating device according to claim 1, wherein the two sides of the top of the outer sleeve (1) are provided with limiting grooves (3), and the outer side of the limiting ring (22) is matched with the inner part of the limiting grooves (3) in a clamping manner.

3. The chylomicron separation device according to claim 1, wherein the bottom of the limit ring (22) is provided with a clamping groove (4), and the top of the outer sleeve (1) is clamped in the clamping groove (4).

4. The chylomicron separation device according to claim 1, wherein an annular groove (8) is provided on the outer side of the bottom of the inner sleeve (21), and a sealing ring (5) is provided inside the annular groove (8).

5. The chylomicron separation device according to claim 1, wherein the bottom of the inner sleeve (21) is connected with a shrink ring (6), the bottom of the first filter screen (23) is provided with a second filter screen (7), and the outer side of the second filter screen (7) is connected with the inside of the shrink ring (6).