CN220141871U - Multifunctional mouse fixing device - Google Patents
Multifunctional mouse fixing device Download PDFInfo
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- CN220141871U CN220141871U CN202321567647.3U CN202321567647U CN220141871U CN 220141871 U CN220141871 U CN 220141871U CN 202321567647 U CN202321567647 U CN 202321567647U CN 220141871 U CN220141871 U CN 220141871U
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- orifice plate
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- 238000002474 experimental method Methods 0.000 claims abstract description 81
- 241000699666 Mus <mouse, genus> Species 0.000 claims abstract description 39
- 208000002193 Pain Diseases 0.000 claims abstract description 38
- 230000036407 pain Effects 0.000 claims abstract description 38
- 241000699670 Mus sp. Species 0.000 claims abstract description 17
- 238000012360 testing method Methods 0.000 claims abstract description 6
- 238000004659 sterilization and disinfection Methods 0.000 claims description 12
- 239000007921 spray Substances 0.000 claims description 5
- 238000005192 partition Methods 0.000 claims description 3
- 230000001954 sterilising effect Effects 0.000 claims description 2
- 239000008280 blood Substances 0.000 abstract description 12
- 210000004369 blood Anatomy 0.000 abstract description 12
- 238000005259 measurement Methods 0.000 abstract description 6
- 241001465754 Metazoa Species 0.000 abstract description 4
- 201000010099 disease Diseases 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 238000011160 research Methods 0.000 description 4
- 238000010171 animal model Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 241000282414 Homo sapiens Species 0.000 description 2
- 210000003608 fece Anatomy 0.000 description 2
- 230000008506 pathogenesis Effects 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241000524057 Acacia fleckii Species 0.000 description 1
- 208000000114 Pain Threshold Diseases 0.000 description 1
- 238000001467 acupuncture Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000010871 livestock manure Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000037040 pain threshold Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
Abstract
The utility model discloses a multi-functional mouse fixing device of animal experiment apparatus technical field, including the experiment case of a plurality of intercommunications, separate through the baffle between the experiment case, experiment case bottom fixedly connected with support, the experiment case includes first experiment case, second experiment case and third experiment case, first experiment case bottom is excreteing the orifice plate, second experiment case bottom is mechanical pain survey orifice plate, third experiment case bottom is thermal pain survey test plate, all there are a plurality of holes that are equipped with on excreteing orifice plate and the mechanical pain survey orifice plate, the terminal surface that the second experiment case was kept away from to first experiment case is equipped with semicircular operating hole. The device can be used for carrying out tail breaking and blood taking, mechanical pain measurement and thermal pain measurement experiments of mice in the same device.
Description
Technical Field
The utility model belongs to the technical field of animal experiment tools, and particularly relates to a multifunctional mouse fixing device.
Background
The disease animal model is a common tool in the field of medical research, and is used for simulating the pathogenesis and conditions of clinical diseases of human beings by experimental animals and establishing similar disease occurrence and development states so as to research the pathogenesis, diagnosis and treatment of the diseases. Is the most effective tool for researching human diseases, and is helpful for more conveniently researching disease control measures. At present, a large blank exists for constraint and auxiliary intervention devices of experimental animals, a novel auxiliary intervention device is developed, better intervention stimulation is facilitated, experimental research efficiency is improved, and labor cost is saved.
Experimental mice are commonly used in the teaching and research of subjects such as physiology, medicine and pharmacy, in a specific experimental process, experimental staff often need to perform operations such as injecting samples and drawing blood on the experimental mice, and the experimental staff is easy to bite by the experimental mice during the operation, so that the experimental mice are fixed by adopting corresponding fixing devices before starting the operation. The tail-breaking blood taking, mechanical pain measuring and thermal pain measuring of the mice are common test experiments in the mouse experiments, and are usually required to be carried out continuously, however, the tail-breaking blood taking, the mechanical pain measuring and the thermal pain measuring of the mice are required to be carried out in three different devices at present, so that the operation risk of experimenters is increased in the grabbing process of the mice, and meanwhile, the experimenters are injured artificially. Therefore, it is highly desirable to design a multifunctional mouse fixing device that can perform experiments of tail breaking and blood taking, mechanical pain measurement and thermal pain measurement of a mouse in the same device.
Disclosure of Invention
The utility model aims to provide a multifunctional mouse fixing device, and provides a device for carrying out experiments of tail breaking and blood taking, mechanical pain measurement and thermal pain measurement of a mouse in the same device.
The utility model provides a multi-functional mouse fixing device, including the experimental box of a plurality of intercommunications, separate through the baffle between the experimental box, experimental box bottom fixedly connected with support, the experimental box includes first experimental box, second experimental box and third experimental box, first experimental box bottom is excreteing the orifice plate, second experimental box bottom is mechanical pain survey orifice plate, third experimental box bottom is thermal pain survey test plate, all have on excreteing orifice plate and the mechanical pain survey orifice plate and be equipped with a plurality of holes, the terminal surface that the second experimental box was kept away from to first experimental box is equipped with semicircular operating hole.
The working principle of the scheme and the beneficial effects thereof are that: when carrying out the experiment, close the baffle between the experimental box, place the mouse in first experimental box, take out the tail of mouse from the operation hole, the mouse grasps the hole on excreteing the orifice plate and climbs forward when struggling, the operator carries out the tail breaking and gets blood at the operation hole department, after the tail breaking and gets blood successfully, open the baffle between first experimental box and the second experimental box, after the mouse gets into the second experimental box, close the baffle, and use the acupuncture end of mechanical pain tester to pass mechanical pain survey orifice plate thorn mouse sole, observe the mouse pain threshold on the instrument, after mechanical pain survey is accomplished, open the baffle between second experimental box and the third experimental box, with the thermal pain survey test plate intercommunication thermal pain appearance, observe the mouse through thermal pain appearance and lift foot number of times and time. Through this device, can accomplish the mouse fast and cut off the tail and get blood, mechanical pain survey and the experiment of thermal pain survey, and in the experimentation, need not the operator to grab the mouse and change experimental apparatus, only need open the baffle can shift the mouse, this device can improve the security of experiment, and can improve experimental efficiency.
Further, the first experiment box is internally provided with four binding bands for fixing the mice. When the tail breaking and blood taking experiment is carried out, the limbs of the mice are fixed by using the binding bands, so that the mice are limited to struggle, and the experiment can be conveniently carried out.
Further, the second experiment box and the third experiment box are far away from the end part sliding connection of the first experiment box and are provided with placing grooves. In the experiment, animal feces were placed in a holding tank, and the mice were attracted to advance to the next room by smell.
Further, first experiment case and second experiment case bottom fixedly connected with supporter is equipped with the collection box on the supporter. The excrement of the mice operated in the first experiment box and the second experiment box can be discharged into the collecting box through the holes, so that experimenters can conveniently treat the excrement of the mice.
Further, a disinfection tube is arranged at the top of the experiment box. After the experiment is completed, the disinfection tube can be opened, so that the disinfection liquid is sprayed into the experiment box, the experiment box can be disinfected in time, and the condition that the wound on the four limbs of the mouse is infected when excrement is remained on the holes is avoided.
Further, the sterilizing pipes are uniformly provided with spray heads. When the disinfection is performed, the spray head is opened, the disinfection water is sprayed into the experiment box by the spray head, and the experiment box is sprayed by the spray head, so that the disinfection water in the experiment box is sprayed more uniformly, and the disinfection is facilitated.
Further, a light shielding film is arranged on the partition board. The shading film is arranged on the partition board, so that a dark environment can be created, and rapid quiescence of mice is facilitated.
Drawings
Fig. 1 is a schematic structural diagram of a multifunctional mouse fixing device according to the present utility model.
Detailed Description
The following is a further detailed description of the embodiments:
reference numerals in the drawings of the specification include: experiment box 1, thermal pain determination test plate 2, bracket 3, commodity shelf 4, collecting box 5, mechanical pain determination pore plate 6, drain pore plate 7, operation hole 8, disinfection tube 9, shower nozzle 10, bandage 11, baffle 12, standing groove 13.
An example is substantially as shown in figure 1: including the experiment case 1 of a plurality of intercommunications, separate through baffle 12 between the experiment case 1, be equipped with the shading membrane on the baffle 12, experiment case 1 bottom fixedly connected with support 3, experiment case 1 includes first experiment case 1, second experiment case 1 and third experiment case 1, install the bandage 11 of four fixed mice in the first experiment case 1, first experiment case 1 bottom is excreted orifice plate 7, second experiment case 1 bottom is mechanical pain survey orifice plate 6, third experiment case 1 bottom is thermal pain survey orifice plate 2, all be equipped with a plurality of holes on excreting orifice plate 7 and the mechanical pain survey orifice plate 6, the terminal surface that second experiment case 1 was kept away from to first experiment case 1 is equipped with semicircular operating hole 8, the tip sliding connection that first experiment case 1 was kept away from to second experiment case 1 and third experiment case 1 has standing groove 13, first experiment case 1 and second experiment case 1 bottom fixedly connected with supporter 4, be equipped with supporter 5 on 4, experiment case 1 top is equipped with disinfection pipe 9, evenly distributed has shower nozzle 10 on the disinfection pipe 9.
Taking the embodiment as an example, the specific implementation process is as follows: when carrying out the experiment, close the baffle between the experiment case 1, place the mouse in first experiment case 1, use bandage 11 fixed with the four limbs of mouse, it struggles to restrict the mouse, tail with the mouse is taken out from operation hole 8 departments, the mouse is when struggling to grasp the hole on the excretory orifice plate 7 and climb forward, the operator carries out the tail to the mouse and gets blood, after the tail gets blood successfully, open the baffle between first experiment case 1 and the second experiment case 1, place animal manure in standing groove 13, attract the mouse to the next operation room through the smell and go forward, after the mouse gets into second experiment case 1, and use the needled end of mechanical pain tester to pass mechanical pain survey orifice plate 6 thorn mouse sole, observe the mouse pain domain value on the instrument, after mechanical pain survey is accomplished, open the baffle between second experiment case 1 and the third experiment case 1, with thermal pain tester plate 2 intercommunication thermal pain appearance, lift the mouse foot and time, the shower nozzle 10 can be opened to the shower nozzle 10 in the time of the experiment case 1, can be realized to the shower nozzle 10, the shower nozzle 10 is passed through the shower nozzle is opened to the experiment case 1, can be more convenient, the disinfection experiment is carried out in the shower nozzle 10, the experiment is carried out the shower nozzle is carried out in the shower nozzle is 10 to the shower nozzle is carried out in the experiment case, the shower nozzle is more convenient for the experiment is 10, the shower nozzle is 10 to the shower nozzle is worth the end.
The foregoing is merely exemplary embodiments of the present utility model, and specific structures and features that are well known in the art are not described in detail herein. It should be noted that modifications and improvements can be made by those skilled in the art without departing from the structure of the present utility model, and these should also be considered as the scope of the present utility model, which does not affect the effect of the implementation of the present utility model and the utility of the patent. The protection scope of the present utility model is subject to the content of the claims, and the description of the specific embodiments and the like in the specification can be used for explaining the content of the claims.
Claims (7)
1. A multifunctional mouse fixing device, which is characterized in that: including the experimental box of a plurality of intercommunications, separate through the baffle between the experimental box, experimental box bottom fixedly connected with support, experimental box include first experimental box, second experimental box and third experimental box, and first experimental box bottom is excreteing the orifice plate, and second experimental box bottom is mechanical pain survey orifice plate, and third experimental box bottom is thermal pain survey and tests the board, all has on excreteing orifice plate and the mechanical pain survey orifice plate to be equipped with a plurality of holes, and the terminal surface that the second experimental box was kept away from to first experimental box is equipped with semicircular operating hole.
2. The multi-functional mouse fixing means according to claim 1, wherein: four binding bands for fixing mice are arranged in the first experiment box.
3. A multi-functional mouse fixing means as claimed in claim 2, wherein: the second experiment box and the third experiment box are far away from the end part sliding connection of the first experiment box and are provided with placing grooves.
4. A multi-functional mouse fixing means as claimed in claim 3, wherein: first experiment case and second experiment case bottom fixedly connected with supporter are equipped with the collection box on the supporter.
5. The multi-functional mouse fixing means of claim 4, wherein: the top of the experiment box is provided with a disinfection tube.
6. The multi-functional mouse fixing means of claim 5, wherein: the sterilizing pipes are uniformly provided with spray heads.
7. The multi-functional mouse fixing means of claim 6, wherein: and a shading film is arranged on the partition board.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321567647.3U CN220141871U (en) | 2023-06-19 | 2023-06-19 | Multifunctional mouse fixing device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321567647.3U CN220141871U (en) | 2023-06-19 | 2023-06-19 | Multifunctional mouse fixing device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220141871U true CN220141871U (en) | 2023-12-08 |
Family
ID=89014425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321567647.3U Active CN220141871U (en) | 2023-06-19 | 2023-06-19 | Multifunctional mouse fixing device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220141871U (en) |
-
2023
- 2023-06-19 CN CN202321567647.3U patent/CN220141871U/en active Active
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