CN220089691U - Batch fixing device for intravenous injection of tail of mice - Google Patents
Batch fixing device for intravenous injection of tail of mice Download PDFInfo
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- CN220089691U CN220089691U CN202321564337.6U CN202321564337U CN220089691U CN 220089691 U CN220089691 U CN 220089691U CN 202321564337 U CN202321564337 U CN 202321564337U CN 220089691 U CN220089691 U CN 220089691U
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- mouse
- tail
- clamping mechanism
- groove
- injection
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- 241000699670 Mus sp. Species 0.000 title claims abstract description 22
- 238000010253 intravenous injection Methods 0.000 title claims abstract description 16
- 241000699666 Mus <mouse, genus> Species 0.000 claims abstract description 43
- 238000002347 injection Methods 0.000 claims abstract description 21
- 239000007924 injection Substances 0.000 claims abstract description 21
- 230000007246 mechanism Effects 0.000 claims abstract description 21
- 210000003462 vein Anatomy 0.000 claims abstract description 17
- 238000005286 illumination Methods 0.000 claims abstract description 16
- 241000581650 Ivesia Species 0.000 claims abstract description 15
- 238000001990 intravenous administration Methods 0.000 claims description 4
- 210000004204 blood vessel Anatomy 0.000 abstract description 4
- 238000006243 chemical reaction Methods 0.000 abstract description 4
- 230000006835 compression Effects 0.000 abstract description 4
- 238000007906 compression Methods 0.000 abstract description 4
- 230000000007 visual effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 description 9
- 238000002474 experimental method Methods 0.000 description 7
- 230000008569 process Effects 0.000 description 7
- 230000000694 effects Effects 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 206010040007 Sense of oppression Diseases 0.000 description 2
- 238000002791 soaking Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010047139 Vasoconstriction Diseases 0.000 description 1
- 230000015624 blood vessel development Effects 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004630 mental health Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- 230000025033 vasoconstriction Effects 0.000 description 1
Abstract
The utility model relates to the technical field of experimental equipment, and particularly provides a batch fixing device for intravenous injection of mouse tails, which comprises an operation platform, wherein a plurality of sleeves for fixing the mice are arranged on the operation platform, a groove for placing the mouse tails is formed in one end of each sleeve, a clamping mechanism for fixing the mouse tails is arranged outside each groove, each clamping mechanism comprises a U-shaped support, an air bag is adhered to the inner side of each U-shaped support, and each U-shaped support is fixedly connected with each sleeve. According to the utility model, the mouse is safely fixed through the cooperation of the plurality of fixed mouse sleeves, the clamping mechanism and the illuminating lamp, so that the situation that an experimenter is bitten by the mouse due to the stress reaction of the mouse is avoided, meanwhile, the air bag device enables the tail vein of the mouse to flow back and be blocked and filled due to the compression, the puncture success rate is improved, the blood vessel of the mouse can be fully developed through illumination, the visual field definition of the operator is improved, and the plurality of fixed barrels can be used for experimental batch tail vein injection, so that the injection success rate and experimental efficiency are further improved.
Description
Technical Field
The utility model relates to the technical field of experimental equipment, in particular to a batch fixing device for intravenous injection of a tail part of a mouse.
Background
Intravenous injection into the tail of a mouse is a commonly used experimental method in the fields of pharmacology, toxicology, genetics, tumors, immunology and other experiments, but has low success rate of freehand operation in the experiments, especially for inexperienced experimenters. The mouse tail vein is thinner, the observation is not obvious, the needle insertion is difficult, the problems of difficult fixation, struggling after frightening, vasoconstriction after cooling and the like of the mouse are further increased, the operation difficulty is increased, even the occurrence of the event that the mouse bites an experimenter is caused, the experiment difficulty is increased, the experiment process is prolonged, and the physical and mental health of the experimenter is also damaged to a certain extent.
At present, a plurality of mouse tail intravenous injection devices exist, but the problems that the comfort level of the mice is low, the struggle is caused, the tail vein is contracted due to incapacity of regulating and controlling the temperature, the blood vessel development is poor due to poor illumination and the like are still limited in application, and most of the mice are fixed by single mice, so that the experimental operation cannot be completed efficiently.
Disclosure of Invention
The utility model aims to provide a batch fixing device for intravenous injection of a tail part of a mouse, which is characterized in that the body position and the tail part of the mouse are fixed through a clamping mechanism and a fixing sleeve, the blood vessel position of the tail part of the mouse is fully exposed in the sight of an operator, and the operation difficulty is reduced; the problems of low tail vein injection success rate, low experimental efficiency, increased animal pain due to repeated puncture and physical and psychological damage of a mouse bitten person to an experimenter in a mouse experiment are solved; the utility model has simple structure and greatly improves the injection success rate and experimental efficiency.
In order to achieve the above purpose, the present utility model provides the following technical solutions:
the utility model provides a batch fixing device for intravenous injection of a tail part of a mouse, which comprises an operation platform, wherein a plurality of sleeves for fixing the mouse are arranged on the operation platform, a groove for placing the tail part of the mouse is arranged at one end of each sleeve, a clamping mechanism for fixing the tail part of the mouse is arranged at the outer side of each groove, each clamping mechanism comprises a U-shaped bracket, an air bag is adhered to the inner side of each U-shaped bracket, and each U-shaped bracket is fixedly connected with each sleeve.
Specifically, clamping mechanism still includes the illumination groove, illumination groove and operation platform fixed connection, install the illumination LED lamp on the illumination groove.
Specifically, the illumination LED lamp is also connected with a switch and a storage battery.
Specifically, the sleeve comprises a bottom shell and an upper shell, the bottom shell is movably connected with the upper shell through a hinge, a binding belt is arranged on the bottom shell to fix the body position of the mouse, and the upper shell is in a grid shape.
Specifically, both ends of the bottom shell are closed, and the through hole is arranged at one end close to the clamping mechanism.
Specifically, the horizontal vertical position of the bottom of the inner side groove of the U-shaped bracket is the same as that of the bottom of the groove.
Specifically, the number of the clamping mechanisms corresponds to the number of the operating platforms.
Based on the technical scheme, the embodiment of the utility model at least has the following technical effects:
according to the batch fixing device for intravenous injection of the tail part of the mouse, provided by the utility model, the compression of the U-shaped air bag is added at the root part of the tail part of the mouse, so that the tourniquet effect of clinical intravenous puncture can be simulated, the appearance of veins is increased after blood flow is blocked, and the success rate of injection is greatly improved; the traditional tail vein injection usually adopts warm water soaking, alcohol wiping and other methods to pre-relax tail veins and then perform injection, in the process, the mice can generate stress reactions with different degrees, and the injection success rate is low.
Drawings
The accompanying drawings are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate the utility model and together with the embodiments of the utility model, serve to explain the utility model.
FIG. 1 is a schematic overall structure of an embodiment of the present utility model;
FIG. 2 is a schematic view of a sleeve structure according to an embodiment of the present utility model;
in the figure: 1. an operating platform; 2. a sleeve; 21. a bottom case; 22. an upper case; 23. an upper end; 24. a bottom end; 3. clamping mechanism; 31. a U-shaped bracket; 32. an illumination slot.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the present utility model more apparent, the technical solutions of the present utility model will be described in detail below, and the described embodiments are only some embodiments of the present utility model, but not all embodiments, and all other embodiments obtained by those skilled in the art without making any inventive effort based on the embodiments in the present utility model are included in the scope of protection of the present utility model. The utility model is described in further detail below with reference to the embodiments of the drawings.
As shown in fig. 1-2, the device for batch intravenous injection of the tail of the mice provided by the embodiment of the utility model comprises an operation platform 1, wherein a plurality of sleeves 2 for fixing the mice are arranged on the operation platform 1, specifically, the sleeves 2 comprise a bottom shell 21 and an upper shell 22, the bottom shell 21 and the upper shell 22 are movably connected through a hinge, and the bottom shell 21 is provided with a binding belt for fixing the body of the mice, so that the movable space of the mice in the sleeves 2 is reduced, operators are protected from being grabbed by the mice, and the mice are effectively prevented from escaping unexpected events; wherein the upper shell 22 of the sleeve 2 is grid-shaped, so that the mice can breathe conveniently, and the mice are prevented from struggling uncomfortably in a closed environment, and are prevented from generating excessive stress reaction in the operation process.
As shown in fig. 2, in this embodiment, two ends of the bottom shell 21 are closed, wherein a groove for placing a tail of a mouse is provided at one end of the bottom shell 21 near the clamping mechanism 3, and the tail of the mouse is further fixed by passing the tail of the mouse through the groove and placing the tail of the mouse on the clamping mechanism 3 during the process of capturing and fixing the mouse in the experimental process.
As shown in fig. 2, in this embodiment, the clamping mechanism 3 for fixing the tail of the mouse is installed at the same position outside the groove, the clamping mechanism 3 includes a U-shaped bracket 31, an air bag is adhered to the inner side of the U-shaped bracket 31, and the tourniquet effect of clinical venipuncture is simulated by using the compression of the air bag, so that the vein appearance is increased after the blood flow of the tail of the mouse is blocked, and the success rate of injection is greatly improved.
In this embodiment, the clamping mechanism 3 further includes an illumination slot 32, and the illumination slot 32 is mounted at the rear end of the U-shaped bracket 31, so that an operator can illuminate the tail of the mouse, thereby improving the development of blood vessels in the tail of the mouse and increasing the success rate of injection. The illumination groove 32 is provided with an illumination LED lamp, and the LED lamp is connected with a switch and a storage battery to provide power control for the LED lamp; because experimental mice are different in size, the tail length is inconsistent, the positions which are required to be illuminated by injection are inconsistent, in the embodiment, the LED lamp is set to be long, the length of the LED lamp is equivalent to the length of the tail of the mice, the position of the illuminating lamp is not required to be adjusted for many times, and the injection operation of operators is convenient.
In the embodiment, the number of the clamping mechanisms 3 corresponds to the number of the operation platforms 1, so that a plurality of mice can be fixed in the device for injection, and the experimental efficiency is improved.
In order to facilitate understanding of the structure of the batch fixing device for intravenous injection of the tail of the mouse, the following description is provided for the working process of the device:
firstly, the upper shell 22 of the sleeve 2 is opened, a part of soft filler is filled on the bottom shell 21 of the sleeve 2, a grabbing experiment mouse is placed on the bottom shell 21, after the mouse is frightened and stabilized, the mouse is slightly fixed by using a binding belt on the bottom shell 21, the tail of the mouse passes through a groove at the bottom of the bottom shell 21, and then the upper shell 22 is closed, so that the movement space of the mouse is reduced and limited. Then place the mouse tail in the gasbag of U-shaped support 31 inboard, make the gasbag produce the oppression power to the mouse tail, afterbody vein is more fully apparent under the oppression effect easily, remove lighting device on the operation platform 1 to afterbody needs injection position department, develop the mouse tail blood vessel through the light, can clearly see the mouse tail vein position, at this moment, operating personnel can carry out afterbody intravenous route to the mouse, reduced the injection degree of difficulty, improve experimental success rate.
According to the batch fixing device for intravenous injection of the tail part of the mouse, provided by the embodiment of the utility model, the compression of the U-shaped air bag is added at the root part of the tail part of the mouse, so that the tourniquet effect of clinical intravenous puncture can be simulated, the appearance of veins is increased after blood flow is blocked, the success rate of puncture is greatly improved, and the air bag can be loosened after the puncture is successful, so that the injection can be performed; the traditional tail vein injection usually adopts warm water soaking, alcohol wiping and other methods to pre-relax tail veins for injection, because the tail veins of the mice are very thin, even if the mice are seen to be difficult to puncture successfully, and in the process, the mice can have different degrees of stress reactions, and the injection success rate is lower.
Finally, it should be noted that: in the description of the present utility model, it should be noted that the azimuth or positional relationship indicated by the terms "upper", "lower", "horizontal", etc. are based on the azimuth or positional relationship shown in the drawings, and are merely for convenience of describing the present utility model and simplifying the description, and do not indicate or imply that the apparatus or element to be referred to must have a specific azimuth, be constructed and operated in a specific azimuth, and thus should not be construed as limiting the present utility model.
It will be understood that the utility model has been described in terms of several embodiments, and that various changes and equivalents may be made to these features and embodiments by those skilled in the art without departing from the spirit and scope of the utility model. In addition, many modifications may be made to adapt a particular situation or material to the teachings of the utility model without departing from the essential scope thereof. Therefore, it is intended that the utility model not be limited to the particular embodiment disclosed, but that the utility model will include all embodiments falling within the scope of the appended claims.
Claims (7)
1. The utility model provides a mouse tail intravenous route is fixing device in batches, its characterized in that, including operation platform (1), be equipped with a plurality of sleeve (2) that are used for fixed mouse on operation platform (1), sleeve (2) one end is equipped with the recess that is used for placing the mouse tail, clamping mechanism (3) of fixed mouse tail are installed in the recess outside, clamping mechanism (3) include U-shaped support (31), the inboard bonding of U-shaped support (31) has the gasbag, U-shaped support (31) and sleeve (2) fixed connection.
2. The device for batch fixation of intravenous injection of mouse tail according to claim 1, wherein the clamping mechanism (3) further comprises an illumination groove (32), the illumination groove (32) is fixedly connected with the operation platform (1), and an illumination LED lamp is installed on the illumination groove (32).
3. The mouse tail vein injection batch fixing device according to claim 2, wherein the lighting LED lamp is further connected with a switch and a storage battery.
4. The batch fixing device for intravenous injection of the tail of the mouse according to claim 1, wherein the sleeve (2) comprises a bottom shell (21) and an upper shell (22), the bottom shell (21) and the upper shell (22) are movably connected through a hinge, a binding belt is arranged on the bottom shell (21) to fix the body position of the mouse, and the upper shell (22) is in a grid shape.
5. The batch fixing device for intravenous injection of mouse tail according to claim 4, wherein two ends of the bottom shell (21) are closed, and the groove is arranged on one end close to the clamping mechanism (3).
6. A tail vein injection batch fixing apparatus as claimed in claim 1, wherein the bottom of the inner side groove of the U-shaped bracket (31) is the same as the horizontal vertical position of the bottom of the groove.
7. The device for fixing the intravenous injection batches of the tail of the mice according to claim 1, wherein the number of the clamping mechanisms (3) corresponds to the number of the operating platforms (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321564337.6U CN220089691U (en) | 2023-06-19 | 2023-06-19 | Batch fixing device for intravenous injection of tail of mice |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321564337.6U CN220089691U (en) | 2023-06-19 | 2023-06-19 | Batch fixing device for intravenous injection of tail of mice |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220089691U true CN220089691U (en) | 2023-11-28 |
Family
ID=88869468
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321564337.6U Active CN220089691U (en) | 2023-06-19 | 2023-06-19 | Batch fixing device for intravenous injection of tail of mice |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220089691U (en) |
-
2023
- 2023-06-19 CN CN202321564337.6U patent/CN220089691U/en active Active
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