CN213156668U - Mouse tail intravenous route fixing device - Google Patents
Mouse tail intravenous route fixing device Download PDFInfo
- Publication number
- CN213156668U CN213156668U CN202020472640.3U CN202020472640U CN213156668U CN 213156668 U CN213156668 U CN 213156668U CN 202020472640 U CN202020472640 U CN 202020472640U CN 213156668 U CN213156668 U CN 213156668U
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- CN
- China
- Prior art keywords
- mouse
- barrel
- tail
- fixing device
- injection
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- Expired - Fee Related
Links
- 241000581650 Ivesia Species 0.000 title claims abstract description 28
- 238000001990 intravenous administration Methods 0.000 title description 8
- 238000010253 intravenous injection Methods 0.000 claims abstract description 14
- 229920001971 elastomer Polymers 0.000 claims abstract description 13
- 230000007246 mechanism Effects 0.000 claims abstract description 11
- 230000005484 gravity Effects 0.000 claims abstract description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 24
- 238000005192 partition Methods 0.000 claims description 10
- 229920002379 silicone rubber Polymers 0.000 claims description 5
- 229920003229 poly(methyl methacrylate) Polymers 0.000 claims description 3
- 239000004926 polymethyl methacrylate Substances 0.000 claims description 3
- 239000004945 silicone rubber Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 2
- 239000012780 transparent material Substances 0.000 claims description 2
- 238000002347 injection Methods 0.000 abstract description 26
- 239000007924 injection Substances 0.000 abstract description 26
- 210000003462 vein Anatomy 0.000 abstract description 16
- 230000006378 damage Effects 0.000 abstract description 6
- 238000000034 method Methods 0.000 abstract description 6
- 206010040007 Sense of oppression Diseases 0.000 abstract description 3
- 208000027418 Wounds and injury Diseases 0.000 abstract description 3
- 208000014674 injury Diseases 0.000 abstract description 3
- 241000699666 Mus <mouse, genus> Species 0.000 description 53
- 241000699670 Mus sp. Species 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 238000013461 design Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000037237 body shape Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000007928 intraperitoneal injection Substances 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
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Abstract
The utility model relates to a mouse tail intravenous injection fixing device, which comprises a cylinder body and a loading mechanism arranged on the cylinder body, wherein the loading mechanism is used for adjusting the gravity of the cylinder body; the barrel is a hollow barrel, and a rubber gasket matched with the barrel is arranged at the edge of an opening at the bottom of the barrel. The utility model discloses can alleviate mouse tail intravenous injection's misery, avoid the mouse in tail intravenous injection in-process struggle the influence that causes tail intravenous injection, in addition through the moderate degree oppression of heavy burden mechanism to the mouse afterbody, can make mouse tail vein blood vessel sufficient rapidly, clearly can distinguish, shortened the injection required time, and can not cause the injury to the afterbody of mouse, improved mouse tail intravenous injection's efficiency greatly.
Description
Technical Field
The utility model relates to an animal fixing device technical field, concretely relates to mouse tail intravenous route fixing device.
Background
The mouse is the most commonly used experimental animal in scientific research experiments at present, and the administration modes of the experimental mouse comprise tail vein injection, gastric perfusion administration, intraperitoneal injection, subcutaneous injection and the like, wherein the tail vein injection is one of the most common administration modes, but the mouse is lively and well-moved naturally, reacts violently under external stimulation, even scratches and bites an operator, so that great difficulty is brought to the fixed mouse, and the difficulty of tail vein injection is greatly increased.
The traditional mouse tail vein injection device is generally used for completely confining the body of a mouse in a narrow space and only exposing the tail part for injection, and the narrow space cannot be suitable for the sizes of all mouse body types, so that the type of the mouse suitable for the injection is very limited, the mouse can be frightened and painful to cause severe struggle, and certain damage can be caused to an experimental mouse; in addition, because the whole injection device can not be well fixed on the operation platform, the whole displacement of the device is caused when a mouse struggles, even injection can be carried out by cooperation of multiple people, the injection efficiency is low, and more parts are arranged in a large-scale device, the structure is complex, the device is not convenient to carry, and the price is high and the cost is high.
Therefore, the mouse tail vein injection fixing device which is simple in structure, convenient to operate and capable of greatly improving injection efficiency is urgently needed to be found.
SUMMERY OF THE UTILITY MODEL
The defect or not enough to prior art exists, the utility model aims at providing a mouse tail intravenous injection fixing device, can alleviate mouse tail intravenous injection's misery, avoided the mouse struggle in tail intravenous injection in-process and led to the fact the influence to tail intravenous injection, in addition, through the moderate degree oppression of heavy burden mechanism and barrel to the mouse afterbody, can make mouse tail vein blood vessel be full rapidly, it is clear can, the required time of injection has been shortened, and can not cause the injury to the afterbody of mouse, the efficiency of mouse tail intravenous injection has been improved greatly.
In order to achieve the purpose, the utility model adopts the technical proposal that:
a mouse tail intravenous injection fixing device comprises a cylinder body and a loading mechanism arranged on the cylinder body, wherein the loading mechanism is used for adjusting the gravity of the cylinder body; the barrel is a hollow barrel, and a rubber gasket matched with the barrel is arranged at the edge of an opening at the bottom of the barrel.
The barrel body of the fixing device can realize the effect of separating the body and the tail of a mouse, so that the body of the mouse is positioned in the barrel, and the tail of the mouse is positioned outside the barrel; the pressure generated by the gravity of the loading mechanism can ensure that the lower edge of the cylinder body can well fix the root of the mouse tail; the large space in the barrel can accommodate mice with different sizes, and meanwhile, the design of separating the body from the tail can ensure certain moving space of other parts except the tail, so that the pain of the mice can be relieved. Struggle action that mouse body and four limbs produced can not produce any influence to the intravenous route of afterbody in the injection process, can improve tail intravenous route efficiency greatly.
In the tail vein injection process, the elastic organic silicon rubber gasket arranged at the lower opening of the cylinder body is in direct contact with the tail of the mouse, so that pressure can be generated to firmly fix the tail of the mouse, and the body of the mouse and the tail of the mouse can be effectively separated; meanwhile, the mouse tail can be protected from being damaged due to the increase of the stress area, the compression on the tail of the mouse can not cause any damage to the mouse in a short time, the tail vein blood vessel of the mouse can be quickly filled, the mouse tail vein blood vessel slightly bulges and is clearly distinguished, and the time required by injection is greatly shortened.
Preferably, a plurality of air holes communicated with the inner cavity are formed in the wall of the barrel body, so that normal breathing of a mouse can be better ensured, and the comfortableness of the mouse is improved to reduce struggling of the mouse.
Preferably, the weight-bearing mechanism comprises a clapboard and a weight adjusting part, wherein the clapboard seals the top opening of the cylinder and is used for supporting and placing the weight adjusting part; the weight adjustment member is located above the partition plate.
Further preferably, the weight adjusting component is a water container, a proper amount of water can be added according to the body shape and the body weight of the mouse, the pressure generated by the gravity can well fix the root of the tail of the mouse, and the compression in a short time can fill and clearly identify the tail vein blood vessel of the mouse, so that the injection is easy without causing damage to the mouse.
Preferably, the water container is also provided with a rubber plug matched with the opening of the water container to prevent water in the water container from splashing.
Preferably, a fence is further arranged around the upper part of the partition board, and the height of the fence is at least 2/3 of the height of the water container, so that the weight adjusting part cannot slide down due to bumping caused by the movement of the mouse.
Preferably, the barrel is made of a transparent material, so that the state of the mouse can be observed conveniently during tail vein injection. Specifically, the material of the barrel is polymethyl methacrylate.
Preferably, the rubber gasket is a silicone rubber gasket, and the silicone rubber gasket is durable and has good elasticity, so that the gravity can be well transferred to fix the root of the mouse tail, and meanwhile, the stress area of the tail is increased to protect the mouse tail from being injured.
When the device is used for injecting a mouse, a certain volume of water is added into a water container according to the weight of the mouse. The mouse body is covered by the cylinder buckle, the rubber gasket is pressed at the root of the tail of the mouse, and then the water container is rapidly arranged in the fence to complete the fixation of the mouse, so that the subsequent injection operation is convenient.
Compared with the prior art, the utility model discloses following beneficial effect has:
1. the utility model discloses a fixing device can realize carrying out the divided effect with the body and the tail of mouse, causes struggling action that mouse body and four limbs produced in the injection process can not produce any influence to the intravenous route of afterbody, can improve tail intravenous route efficiency greatly, and simultaneously, certain activity space in its other positions except the tail can be guaranteed in this kind of body and tail divided design, can alleviate the misery of mouse.
2. The structure of the cylinder body can ensure that the interior has larger space, can hold mice with different body sizes, and greatly increases the application range of mouse types.
3. The device simple structure, portable can produce fixed effect by the gravity of reliable water, easy operation, low cost has good popularization application prospect.
Drawings
FIG. 1 is a schematic view of a mouse tail vein injection fixture;
1. a barrel; 2. a rubber gasket; 3. air holes are formed; 4. a water container; 5. a rubber plug; 6. a partition plate; 7. and (4) fencing.
Detailed Description
The following examples are preferred embodiments of the present invention, but are not intended to limit the scope of the present invention in any manner. The replacement of simple parameters in the embodiments can not be repeated one by one in the embodiments, but the present invention is not limited thereby, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be regarded as equivalent replacement modes, and all should be included in the scope of the present invention.
Embodiment 1 mouse tail intravenous route fixing device
As shown in fig. 1, this example provides a mouse tail vein injection fixture. The fixing device comprises a water container 4 and a polymethyl methacrylate barrel 1, wherein the top opening of the barrel 1 is sealed by a partition plate 6, the water container 4 is positioned above the partition plate 6, the water container 4 is also provided with a rubber plug 5 matched with an opening for use, a fence 7 is further arranged around the upper part of the partition plate 6, the height of the fence 7 is 2/3 of the height of the water container 4, an organic silicon rubber gasket 2 matched for use is arranged at the bottom opening of the barrel, and a plurality of air holes 3 communicated with an inner cavity are formed in the upper end of the barrel wall of the barrel 1.
The embodiment can realize effective separation of the body and the tail of the mouse, avoid the struggle behavior generated by the body and the four limbs of the mouse in the injection process from influencing the intravenous injection at the tail part, greatly improve the tail intravenous injection efficiency, and simultaneously, the design of separating the body and the tail can ensure certain movement space at other parts except the tail, thereby relieving the pain of the mouse; in addition, the device has a larger space in the cylinder body, can accommodate mice with different body sizes, and greatly increases the application range of mouse types; in addition, the bottom of the fixing device adopts an organic silica gel rubber gasket with good elasticity, so that the gravity can be well transferred to fix the root of the mouse tail, and meanwhile, the stress area of the tail is increased to protect the mouse tail from being injured; can add appropriate amount of water according to the body type and the weight of mouse in the dress water container, the root of mouse tail can be fixed well to the pressure that its gravity produced, and the oppression of short time can make mouse tail vein blood vessel fill rapidly, and is clear distinguishable, has shortened the required time of injection, and can not cause the injury to the afterbody of mouse, has improved mouse tail vein injection's efficiency greatly.
When the device is used for injecting a mouse, a certain volume of water is added into the water container 4 according to the weight of the mouse. The body of a mouse is covered by the cylinder body 1, the rubber gasket 2 is pressed at the root of the tail of the mouse, and then the water container 4 is rapidly arranged in the fence 7 to complete the fixation of the mouse, so that the subsequent injection operation is convenient.
It should be understood that the above-described embodiments of the present invention are merely examples for clearly illustrating the present invention, and are not intended to limit the embodiments of the present invention. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. Any modification, equivalent replacement, and improvement made within the spirit and principle of the present invention should be included in the protection scope of the claims of the present invention.
Claims (9)
1. A mouse tail intravenous injection fixing device is characterized by comprising a barrel body (1) and a loading mechanism arranged on the barrel body, wherein the loading mechanism is used for adjusting the gravity of the barrel body; the barrel (1) is a hollow barrel, and a rubber gasket (2) matched with the barrel is arranged at the edge of an opening at the bottom of the barrel.
2. The fixing device according to claim 1, characterized in that the wall of the cylinder (1) is provided with a plurality of air holes (3) communicated with the inner cavity.
3. The fixing device according to claim 1, wherein the weight-bearing mechanism comprises a partition (6) and a weight-adjusting member, the partition (6) closing the top opening of the cylinder (1), the weight-adjusting member being located above the partition (6).
4. A fixture according to claim 3, characterised in that the weight-adjusting means is a water container (4).
5. A fixture according to claim 4, characterised in that the water container (4) is further provided with a rubber stopper (5) for cooperation with its opening.
6. A fixture according to claim 5, characterized in that a fence (7) is arranged around the upper part of the partition (6), and the height of the fence (7) is at least 2/3 of the height of the water container (4).
7. The fixing device according to claim 1, characterized in that the cylinder (1) is made of a transparent material.
8. A fixation device according to claim 7, characterized in that the material of the cylinder (1) is polymethylmethacrylate.
9. The fixing device according to claim 1, characterized in that the rubber gasket (2) is a silicone rubber gasket.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020472640.3U CN213156668U (en) | 2020-04-02 | 2020-04-02 | Mouse tail intravenous route fixing device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020472640.3U CN213156668U (en) | 2020-04-02 | 2020-04-02 | Mouse tail intravenous route fixing device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN213156668U true CN213156668U (en) | 2021-05-11 |
Family
ID=75763856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202020472640.3U Expired - Fee Related CN213156668U (en) | 2020-04-02 | 2020-04-02 | Mouse tail intravenous route fixing device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN213156668U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113693772A (en) * | 2021-09-23 | 2021-11-26 | 天津开发区合普工贸有限公司 | Rapid pressurizing and fixing device for tail vein injection of experimental mice |
| CN113907910A (en) * | 2021-11-18 | 2022-01-11 | 天津开发区合普工贸有限公司 | Experimental mice tail intravenous route flexible pressurization fixing device |
-
2020
- 2020-04-02 CN CN202020472640.3U patent/CN213156668U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113693772A (en) * | 2021-09-23 | 2021-11-26 | 天津开发区合普工贸有限公司 | Rapid pressurizing and fixing device for tail vein injection of experimental mice |
| CN113907910A (en) * | 2021-11-18 | 2022-01-11 | 天津开发区合普工贸有限公司 | Experimental mice tail intravenous route flexible pressurization fixing device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20210511 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |