CN219942792U - Synthesis device of nicotine derivative - Google Patents
Synthesis device of nicotine derivative Download PDFInfo
- Publication number
- CN219942792U CN219942792U CN202321591068.2U CN202321591068U CN219942792U CN 219942792 U CN219942792 U CN 219942792U CN 202321591068 U CN202321591068 U CN 202321591068U CN 219942792 U CN219942792 U CN 219942792U
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- CN
- China
- Prior art keywords
- stirring
- kettle
- kettle cover
- heating
- lifting frame
- Prior art date
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- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical class CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title claims abstract description 34
- 230000015572 biosynthetic process Effects 0.000 title claims abstract description 22
- 238000003786 synthesis reaction Methods 0.000 title claims abstract description 22
- 238000003756 stirring Methods 0.000 claims abstract description 52
- 238000010438 heat treatment Methods 0.000 claims abstract description 44
- 230000007246 mechanism Effects 0.000 claims abstract description 16
- 230000002194 synthesizing effect Effects 0.000 claims abstract description 4
- 238000002156 mixing Methods 0.000 claims description 6
- 238000009434 installation Methods 0.000 claims description 5
- 229910001220 stainless steel Inorganic materials 0.000 claims description 5
- 239000010935 stainless steel Substances 0.000 claims description 5
- 230000008878 coupling Effects 0.000 claims description 4
- 238000010168 coupling process Methods 0.000 claims description 4
- 238000005859 coupling reaction Methods 0.000 claims description 4
- 238000006243 chemical reaction Methods 0.000 abstract description 24
- 229960002715 nicotine Drugs 0.000 description 11
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
- 239000000463 material Substances 0.000 description 7
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 6
- 238000000034 method Methods 0.000 description 5
- JOOXCMJARBKPKM-UHFFFAOYSA-N laevulinic acid Natural products CC(=O)CCC(O)=O JOOXCMJARBKPKM-UHFFFAOYSA-N 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 239000005711 Benzoic acid Substances 0.000 description 3
- -1 base 1 Chemical class 0.000 description 3
- 235000010233 benzoic acid Nutrition 0.000 description 3
- 229940040102 levulinic acid Drugs 0.000 description 3
- VAUQRLHPXWYZRZ-UHFFFAOYSA-N benzoic acid;3-(1-methylpyrrolidin-2-yl)pyridine Chemical compound OC(=O)C1=CC=CC=C1.CN1CCCC1C1=CC=CN=C1 VAUQRLHPXWYZRZ-UHFFFAOYSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000003571 electronic cigarette Substances 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 230000007794 irritation Effects 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 235000019505 tobacco product Nutrition 0.000 description 2
- 235000019504 cigarettes Nutrition 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Landscapes
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
The utility model discloses a nicotine derivative synthesizing device, which comprises a base, wherein a reaction kettle, a collecting tank and a lifting driving mechanism are arranged on the base, the reaction kettle comprises a heating kettle body and a kettle cover, the lifting frame is driven by the lifting driving mechanism to vertically lift, the kettle cover, a stirring motor, a stirring assembly and a condenser are arranged on the lifting frame, the stirring motor and the kettle cover are vertically arranged and respectively and fixedly arranged on the lifting frame, the stirring assembly comprises a stirring shaft and stirring paddles arranged at the bottom of the stirring shaft, the stirring paddles are positioned below the kettle cover, the upper end of the stirring shaft extends upwards above the kettle cover and is fixedly connected with an output shaft of the stirring motor, the inlet end of the condenser is connected with a steam outlet of the kettle cover through a pipeline, the outlet end of the condenser is downward and positioned above the collecting tank, and a vacuum suction port of the kettle cover is connected to a vacuum pump through a pipeline. Compared with the prior art, the utility model has the following advantages: realizes the batch continuous synthesis of the nicotine derivative with stable quality.
Description
Technical Field
The utility model relates to a reaction device, in particular to a synthesis device of a nicotine derivative.
Background
Derivatives such as nicotine and its salts are widely used in new tobacco products represented by electronic cigarettes. Free nicotine is volatile, and has large irritation and poor stability. The nicotine is further prepared into a nicotine derivative, so that the stability of the nicotine can be effectively improved. The nicotine salt prepared by the reaction of nicotine and organic acid is commonly used because of the advantages of moderate stiffness, small irritation, weak miscellaneous gases and the like.
Along with the expansion of the international market of heating cigarettes and the release of national standards of GB41700 electronic cigarettes, the capacity of novel tobacco products is increased increasingly, and the nicotine derivatives required to be used in the formula are also increased. At present, nicotine derivatives are mainly prepared by a laboratory, the amount of synthesized samples is small each time, the requirements cannot be met, and most of glass instruments adopted by the laboratory transmit light, so that nicotine changes color in the synthesis process of the nicotine derivatives, and the stability among batches is poor.
Disclosure of Invention
The utility model aims to overcome the defects of the prior art and provides a synthesis device of nicotine derivatives, so as to realize batch continuous synthesis of nicotine derivatives with stable quality.
The utility model is realized by the following technical scheme:
the utility model provides a synthesizer of nicotine derivative, the on-line screen storage device comprises a base, be equipped with reation kettle on the base, collection tank and lift actuating mechanism, reation kettle includes the heating cauldron body and can dismantle the cauldron lid of being connected with heating cauldron body top, lift actuating mechanism's loose end is fixed with lifting frame, drive lifting frame through lift actuating mechanism and go up and down, install the cauldron lid on the lifting frame, agitator motor, the stirring subassembly, agitator motor and cauldron lid are arranged from top to bottom and fixed mounting respectively on lifting frame, the stirring subassembly includes the (mixing) shaft and sets up the stirring paddle in the (mixing) shaft bottom, stirring paddle is located under the cauldron lid, the (mixing) shaft upper end upwards stretches out on the cauldron lid and with agitator motor's output shaft fixed connection, the entrance point of condenser is connected with the steam outlet of cauldron lid through the pipeline, the exit end of condenser is down and is located the collection tank top, the vacuum suction mouth of cauldron lid passes through the pipe connection to the vacuum pump.
As the preferable scheme of the synthesis device, the bottom of the heating kettle body is provided with a plurality of bottom wheels, and the heating kettle body is supported on the ground through the plurality of bottom wheels.
As the preferable scheme of the synthesis device, the heating kettle body, the kettle cover and the pipelines are all stainless steel pieces.
As the preferable scheme of the synthesis device, a thermometer and a pressure gauge are arranged on the kettle cover.
As the preferable scheme of the synthesis device, the stirring shaft is provided with an upper stirring blade and a lower stirring blade.
As the preferable scheme of above-mentioned synthesizer, heating cauldron body top is equipped with two at least coupling assembling along circumference, and every coupling assembling includes looks threaded connection's connecting rod and bolt, and the connecting rod tip articulates on the heating cauldron body, withholds at cauldron lid top edge through the head of bolt, realizes the fastening installation of cauldron lid and heating cauldron body.
As a preferable scheme of the synthesizing device, the lifting driving mechanism is a linear motor, and the lifting frame is fixedly connected with the output end of the linear motor.
Compared with the prior art, the utility model has the following advantages:
the synthesis device of the nicotine derivative provided by the utility model comprises the reaction kettle, the collection tank and the condenser, integrates reaction and concentration, realizes continuous preparation of the nicotine derivative, is simple and convenient to operate, is safe and reliable, and improves the preparation efficiency; simultaneously, it installs lid, agitator motor, stirring subassembly on lifting frame, can drive lifting frame and the whole of last installation component go up and down through lifting drive mechanism to can drive the lid and go up and down, the lid of being convenient for opens and shuts with the heating cauldron body, the dismantlement and the washing of the heating cauldron body of being convenient for, convenient operation is swift. In addition, the heating kettle body, the kettle cover and each pipeline are made of opaque stainless steel, so that the effect of avoiding light is achieved, nicotine is effectively prevented from changing color when encountering light, and the stability of products among batches is good.
Drawings
Fig. 1 is a schematic structural view of the present utility model.
FIG. 2 is a schematic diagram of the structure of the kettle cover of the utility model lifted off the heating kettle body.
Fig. 3 is a top view of the base of the present utility model.
Fig. 4 is a top view of the present utility model with the bolt head crimped to the kettle cover.
Reference numerals in the drawings: 1, a base; 2, a reaction kettle; 3, collecting a tank; 4, lifting driving mechanism; 5 heating the kettle body; 6, a kettle cover; 7, a bottom wheel; 8 avoiding grooves; 9 connecting rods; 10 bolts; 11 lifting the frame; 12, a stirring motor; 13 a condenser; 14, a stirring shaft; 15 stirring paddles; a 16 thermometer; 17 pressure gauge; 18 charging port; 19 discharge openings; 20 vacuum pump.
Detailed Description
The following describes in detail the examples of the present utility model, which are implemented on the premise of the technical solution of the present utility model, and detailed embodiments and specific operation procedures are given, but the scope of protection of the present utility model is not limited to the following examples.
Referring to fig. 1 to 4, this embodiment discloses a synthesizing device of nicotine derivative, including base 1, be equipped with reation kettle 2, collection tank 3 and lift actuating mechanism 4 on the base 1, reation kettle 2 includes heating cauldron body 5 and can dismantle the cauldron lid 6 of being connected with heating cauldron body 5 top, and heating cauldron body 5 bottom is equipped with a plurality of return pulleys 7, and heating cauldron body 5 supports subaerial through a plurality of return pulleys 7, opens on base 1 and has the avoidance groove 8 that supplies heating cauldron body 5 business turn over to remove. The top end of the heating kettle body 5 is circumferentially provided with at least two connecting components, each connecting component comprises a connecting rod 9 and a bolt 10 which are in threaded connection, the end part of the connecting rod 9 is hinged on the heating kettle body 5 and can be turned up and down, the top edge of the kettle cover 6 is buckled and pressed through the head of the bolt 10, and the fastening installation of the kettle cover 6 and the heating kettle body 5 is realized.
The movable end of the lifting driving mechanism 4 is fixed with a lifting frame 11, and the lifting frame 11 is driven to vertically lift by the lifting driving mechanism 4. Wherein, lifting drive mechanism 4 is linear electric motor, lifting frame 11 and linear electric motor's output fixed connection. The kettle cover 6, the stirring motor 12, the stirring assembly and the condenser 13 are arranged up and down on the lifting frame 11, the stirring motor 12 and the kettle cover 6 are respectively and fixedly arranged on the lifting frame 11, the stirring assembly comprises a stirring shaft 14 and stirring paddles 15 arranged at the bottom of the stirring shaft 14, two layers of stirring paddles 15 are arranged on the stirring shaft 14, the two layers of stirring paddles 15 are positioned below the kettle cover 6, the upper end of the stirring shaft 14 upwards extends out of the kettle cover 6 and is fixedly connected with an output shaft of the stirring motor 12, the stirring shaft 14 is driven to rotate through the stirring motor 12, and accordingly the two layers of stirring paddles 15 on the stirring shaft 14 are driven to rotate together, materials in the reaction kettle 2 can be sufficiently stirred, and wall sticking and wall hanging of the materials are effectively prevented.
The inlet end of the condenser 13 is connected with the steam outlet of the kettle cover 6 through a pipeline, the outlet end of the condenser 13 faces downwards and is positioned above the collecting tank 3, the outlet end of the condenser 13 is communicated with the collecting tank 3 through a hose, the vacuum suction port of the kettle cover 6 is connected to a vacuum pump 20 through a pipeline, and a vacuum environment is provided for the reaction kettle 2 through the vacuum pump 20.
Wherein, heating cauldron body 5, kettle cover 6 and each pipeline are stainless steel spare, adopt stainless steel to play the light-proof effect, have effectively prevented that the nicotine from meeting the photochromism for product stability is good between the batch.
The kettle cover 6 is provided with a thermometer 16 and a pressure gauge 17 for detecting temperature and pressure. The kettle cover 6 is also provided with a charging hole 18.
When the heating kettle body 5 needs to be disassembled, the bolt 10 is rotated, the bolt 10 is gradually screwed out from the connecting rod 9, the total length of the screw rod and the connecting rod 9 is increased, the head of the bolt 10 is gradually separated from the kettle cover 6, and then the connecting assembly is turned outwards, so that the locking of the kettle cover 6 and the heating kettle body 5 can be released. Then the lifting frame 11 is driven by the linear motor to lift up, so that the kettle cover 6 and the stirring assembly are lifted up and away from the heating kettle body 5, and the heating kettle body 5 can be easily removed for cleaning by utilizing the bottom wheel 7 at the bottom of the heating kettle body 5.
When the heating kettle body 5 is required to be installed, the heating kettle body 5 is moved to the lower part of the kettle cover 6, the lifting frame 11 is driven by the linear motor to descend, the kettle cover 6 and the heating kettle body 5 are closed, then each connecting component is turned upwards, the bolts 10 of each connecting component are screwed, and the fastening installation of the kettle cover 6 and the heating kettle body 5 can be realized until the heads of the bolts 10 are pressed on the kettle cover 6. The whole operation process is convenient and quick.
The synthesis process of the levulinic acid nicotine salt by using the synthesis device provided by the embodiment is as follows:
levulinic acid and nicotine sequentially pass through a charging hole 18 of a kettle cover 6 of the reaction kettle 2 and are added into the reaction kettle 2, a stirring motor 12 is started, the stirring motor 12 drives a stirring blade 15 to rotate, materials in the reaction kettle 2 are started to be stirred, a heating kettle body 5 starts to heat the materials in the kettle, the materials in the kettle react, after the reaction is finished, the reaction kettle 2 stops heating and stirring, and a discharge hole 19 at the bottom of the heating kettle body 5 discharges levulinic acid nicotine salt generated by the reaction.
The synthesis process of the benzoic acid nicotine salt by using the synthesis device provided in this example is as follows:
ethanol and benzoic acid are sequentially added into the reaction kettle 2 through a charging hole 18 of a kettle cover 6 of the reaction kettle 2, a stirring motor 12 is started, the stirring motor 12 drives a stirring blade 15 to rotate, materials in the reaction kettle 2 are started to be stirred, a kettle body 5 is heated, the materials in the kettle are started to be heated, after the benzoic acid is completely dissolved, nicotine is added into the reaction kettle 2 through the charging hole 18 of the kettle cover 6, and the nicotine is fully reacted with ethanol solution of the benzoic acid. After the reaction is finished, the vacuum pump 20 and the condenser 13 are started, the reaction kettle 2 is vacuumized, the inside of the reaction kettle 2 starts to be decompressed and concentrated, gas in the reaction kettle 2 enters the condenser 13 to be condensed, solvent ethanol condensed by the condenser 13 is recovered into the collecting tank 3, and the concentration is finished after the ethanol of the condenser 13 does not flow out any more. Then the vacuum pump 20 and the condenser 13 are closed, and when the pressure gauge 17 returns to normal pressure, the benzoic acid nicotine salt in the reaction kettle 2 is discharged from the discharge port 19.
The foregoing description of the preferred embodiments of the utility model is not intended to be limiting, but rather is intended to cover all modifications, equivalents, and alternatives falling within the spirit and principles of the utility model.
Claims (7)
1. A nicotine derivative synthesizing device, comprising a base, characterized in that: be equipped with reation kettle, collecting vessel and lift actuating mechanism on the base, reation kettle includes the heating cauldron body and can dismantle the cauldron lid of being connected with heating cauldron body top, lift actuating mechanism's movable end is fixed with lifting frame, drive lifting frame vertical lift through lift actuating mechanism, install the cauldron lid on the lifting frame, agitator motor, stirring subassembly, the condenser, agitator motor and cauldron lid are arranged from top to bottom and fixed mounting respectively on lifting frame, the stirring subassembly includes the (mixing) shaft and sets up the stirring paddle in the (mixing) shaft bottom, stirring paddle is located under the cauldron lid, the (mixing) shaft upper end upwards stretches out on the cauldron lid and is connected with agitator motor's output shaft fixed connection, the entrance point of condenser is connected with the steam outlet of cauldron lid through the pipeline, the exit end of condenser is down and is located the collecting vessel top, the vacuum suction mouth of cauldron lid passes through the pipe connection to the vacuum pump.
2. A synthesis device of nicotine derivatives according to claim 1, characterized in that: the bottom of the heating kettle body is provided with a plurality of bottom wheels, and the heating kettle body is supported on the ground through the plurality of bottom wheels.
3. A synthesis device of nicotine derivatives according to claim 1, characterized in that: the heating kettle body, the kettle cover and the pipelines are all stainless steel parts.
4. A synthesis device of nicotine derivatives according to claim 1, characterized in that: the kettle cover is provided with a thermometer and a pressure gauge.
5. A synthesis device of nicotine derivatives according to claim 1, characterized in that: the stirring shaft is provided with an upper stirring blade and a lower stirring blade.
6. A synthesis device of nicotine derivatives according to claim 1, characterized in that: the heating kettle body top is equipped with two at least coupling assembling along circumference, and every coupling assembling includes looks threaded connection's connecting rod and bolt, and the connecting rod tip articulates on the heating kettle body, withholds at kettle cover top edge through the head of bolt, realizes the fastening installation of kettle cover and heating kettle body.
7. A synthesis device of nicotine derivatives according to claim 1, characterized in that: the lifting driving mechanism is a linear motor, and the lifting frame is fixedly connected with the output end of the linear motor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321591068.2U CN219942792U (en) | 2023-06-20 | 2023-06-20 | Synthesis device of nicotine derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321591068.2U CN219942792U (en) | 2023-06-20 | 2023-06-20 | Synthesis device of nicotine derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219942792U true CN219942792U (en) | 2023-11-03 |
Family
ID=88550424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321591068.2U Active CN219942792U (en) | 2023-06-20 | 2023-06-20 | Synthesis device of nicotine derivative |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219942792U (en) |
-
2023
- 2023-06-20 CN CN202321591068.2U patent/CN219942792U/en active Active
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