CN219896581U - Biological hemodialysis machine system - Google Patents
Biological hemodialysis machine system Download PDFInfo
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- CN219896581U CN219896581U CN202320439922.7U CN202320439922U CN219896581U CN 219896581 U CN219896581 U CN 219896581U CN 202320439922 U CN202320439922 U CN 202320439922U CN 219896581 U CN219896581 U CN 219896581U
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- 238000001631 haemodialysis Methods 0.000 title claims abstract description 45
- 230000000322 hemodialysis Effects 0.000 title claims abstract description 45
- 238000012544 monitoring process Methods 0.000 claims abstract description 15
- 230000005540 biological transmission Effects 0.000 claims abstract description 12
- 238000002615 hemofiltration Methods 0.000 claims abstract description 11
- 239000008280 blood Substances 0.000 claims description 70
- 210000004369 blood Anatomy 0.000 claims description 70
- 239000012530 fluid Substances 0.000 claims description 51
- 238000001514 detection method Methods 0.000 claims description 35
- 238000007872 degassing Methods 0.000 claims description 25
- 230000036772 blood pressure Effects 0.000 claims description 22
- 238000001914 filtration Methods 0.000 claims description 19
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 10
- 229910052760 oxygen Inorganic materials 0.000 claims description 10
- 239000001301 oxygen Substances 0.000 claims description 10
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 9
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims description 9
- 238000006243 chemical reaction Methods 0.000 claims description 9
- 239000008103 glucose Substances 0.000 claims description 9
- 229960002897 heparin Drugs 0.000 claims description 9
- 229920000669 heparin Polymers 0.000 claims description 9
- 230000003321 amplification Effects 0.000 claims description 7
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 7
- 238000000108 ultra-filtration Methods 0.000 claims description 5
- 238000000034 method Methods 0.000 abstract description 10
- 238000011282 treatment Methods 0.000 abstract description 7
- 238000004891 communication Methods 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 4
- 230000008569 process Effects 0.000 abstract description 4
- 238000000502 dialysis Methods 0.000 description 6
- 239000000706 filtrate Substances 0.000 description 6
- 238000010586 diagram Methods 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 102000004190 Enzymes Human genes 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 208000009304 Acute Kidney Injury Diseases 0.000 description 1
- 206010001526 Air embolism Diseases 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 208000033626 Renal failure acute Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 201000011040 acute kidney failure Diseases 0.000 description 1
- 208000012998 acute renal failure Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 208000020832 chronic kidney disease Diseases 0.000 description 1
- 208000022831 chronic renal failure syndrome Diseases 0.000 description 1
- 238000007485 conventional hemodialysis Methods 0.000 description 1
- 210000001808 exosome Anatomy 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 238000012959 renal replacement therapy Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
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Abstract
The utility model provides a biological hemodialysis machine system, and particularly relates to the technical field of hemodialysis, wherein the biological portable hemodialysis machine system comprises an operation control chip, a temperature control module, a driving module, a hemofiltration device and a monitoring module: the biological portable hemodialysis machine system introduces a control system of a biological module, so that the hemodialysis treatment effect is effectively improved; the data transmission module is introduced, so that cloud medical service, doctor-patient communication and emergency treatment capability in the hemodialysis treatment process can be effectively realized.
Description
Technical Field
The utility model relates to the technical field of hemodialysis, in particular to a biological hemodialysis machine system.
Background
Hemodialysis is one of the renal replacement therapies employed by patients with acute and chronic renal failure. Hemodialysis requires draining blood from a patient to the outside, purifying the blood by passing it through a dialysis machine, and then returning the purified blood to the patient. Current conventional hemodialysis devices require that patients with renal failure receive dialysis treatment three times a week for four hours each. Similarly, uremic patients also require frequent hospital visits to hemodialysis, which limits the patient's personal freedom. Clinical researches show that the introduction of the biological reaction module can reduce the use of dialysate, improve the blood toxin removal efficiency, prolong the hemodialysis time, improve the long-term survival rate and reduce the reciprocating dialysis center and medical care cost of patients.
The utility model aims at improving eyesight by providing a biological hemodialysis machine system, wherein monitoring sensors for blood pressure, bubbles, blood leakage and the like are introduced into the system, and blood viscosity, blood sugar and the like are also introduced into the system as monitoring indexes which are ignored in the dialysis process. The prior dialysis machine is not provided with the detection devices, when the indexes are required to be detected, a pipeline is connected with a luer connector in an external mode and then connected with detection equipment of the indexes, and the detection equipment is usually connected with a blood feedback end of the dialysis machine. On the other hand, the biological hemodialysis machine comprises a specific biological module, and the biological module comprises but is not limited to bioactive substances such as cells, proteins, enzymes, exosomes and the like, so that in order to maintain the activity of the cells and the reactivity of the enzymes in a stable state, the temperature of the whole system needs to be controlled at 37 ℃, and whether the whole system influences the hemodialysis effect or the accuracy of the detection result, therefore, a pH sensor, a dissolved oxygen sensor and a temperature controller are introduced into the system so as to meet the requirements of safety indexes and biological index monitoring of the novel hemodialysis machine.
Disclosure of Invention
In order to solve the technical problem that the existing hemodialysis machine cannot solve the problem that various blood indexes of a dialyzer are difficult to detect simultaneously in the hemodialysis process, the utility model provides a hemodialysis machine system which can detect indexes such as blood pressure, viscosity, blood sugar, flow rate, pH value, dissolved oxygen and the like simultaneously.
The utility model is realized by the following technical scheme:
the utility model discloses a biological hemodialysis machine system, which comprises an operation control chip, a temperature control module, a driving module, a filtering module, a biological module, a monitoring module, a current and voltage acquisition module and a signal amplification module, wherein:
the filtering module comprises a heparin pump, a blood filtering device, an ultrafiltrate pump and a degassing device which are sequentially connected through fluid pipelines;
the biological module comprises a biological reactor which is communicated with a fluid pipeline between an ultrafiltrate pump of the filtering module and the degassing device through the fluid pipeline;
the temperature control module is positioned in a pipeline between the ultrafiltrate pump and the biological module and is connected with the operation control chip;
the monitoring module comprises a first blood pressure sensor, a temperature sensor, a flow sensor, a second blood pressure sensor, a blood viscosity sensor, a pH sensor, a dissolved oxygen sensor, a blood leakage sensor and a bubble sensor;
the temperature sensor detection end is connected with pipeline fluid between the blood filtering device and the bioreactor, the first blood pressure sensor detection end is connected with pipeline fluid between the blood pump and the blood filtering device, the temperature sensor detection end is connected with pipeline fluid between the blood filtering device and the bioreactor, the dissolved oxygen sensor detection end is connected with pipeline fluid between the ultrafiltration pump and the bioreactor, the pH sensor detection end is connected with pipeline fluid of the bioreactor module, the second blood pressure sensor detection end is connected with pipeline fluid between the bioreactor module and the degassing device, the blood viscosity sensor detection end is connected with pipeline fluid between the bioreactor module and the degassing device, the blood glucose sensor detection end is connected with pipeline fluid between the blood filtering device and the degassing device, the bubble sensor detection end is connected with pipeline fluid between the bioreactor module and the degassing device, and the blood leakage sensor detection end is connected with pipeline fluid between the bioreactor module and the degassing device;
the sensor of the monitoring module is connected with the operation control chip through the current and voltage acquisition module and the signal amplification module.
Further, the biological hemodialysis machine system further comprises a driving module, and the driving module is connected with the operation control chip;
the driving module comprises a first driving motor, a second driving motor, a third driving motor, a heparin pump, a blood pump and an ultrafiltration liquid pump, wherein the first motor is electrically connected with the heparin pump, the second driving motor is electrically connected with the blood pump, and the third driving motor is electrically connected with the ultrafiltration liquid pump.
Further, the device also comprises an exchange component, wherein the exchange component comprises an LCD display module and a storage module, and the operation control chip is respectively connected with the storage module and the LCD display module.
Further, the switching assembly further comprises a data interface module and a wireless transmission module, and the operation control chip is respectively connected with the data interface module and the wireless transmission module.
Further, the intelligent alarm device also comprises a buzzer module, wherein the buzzer module is connected with the operation control chip.
Further, the temperature compensation module is connected with the operation control chip.
Further, the intelligent control system also comprises a key module and a power module, wherein the power module and the key module are electrically connected with the operation control chip.
Further, the device also comprises a filter circuit and an A/D conversion module, wherein the signal amplification module, the filter circuit, the A/D conversion module and the operation control chip are sequentially connected.
The utility model has the beneficial effects that:
1. the utility model provides a novel biological hemodialysis machine system, which is introduced with a control system of a biological module, so that the hemodialysis treatment effect is effectively improved; the data transmission module is introduced, so that cloud medical service, doctor-patient communication and emergency treatment capability in the hemodialysis treatment process can be effectively realized.
2. According to the utility model, various detection sensors are introduced into the system, including indexes such as blood pressure, viscosity, blood sugar, flow rate, pH value, dissolved oxygen and the like, so that the requirements of a novel hemodialysis machine on biological module safety indexes and biological index monitoring are met, the physical condition of a patient is monitored and recorded in real time, and the safety of hemodialysis is improved.
Drawings
FIG. 1 is a schematic diagram of a biological hemodialysis machine system of the present utility model.
Fig. 2 is a schematic diagram of one embodiment of a biological hemodialysis machine system of the present utility model.
Fig. 3 is a schematic diagram of one embodiment of a biological hemodialysis machine system of the present utility model.
Fig. 4 is a schematic diagram of one embodiment of a biological hemodialysis machine system of the present utility model.
The realization, functional characteristics and advantages of the present utility model are further described with reference to the accompanying drawings in combination with the embodiments.
Detailed Description
In order to more clearly and completely describe the technical scheme of the utility model, the utility model is further described below with reference to the accompanying drawings.
Referring to fig. 1, the hemodialysis machine system of the present utility model includes an operation control chip, a filtering module, a temperature control module, a monitoring module, a current and voltage acquisition module and a signal amplification module, wherein:
the operation control chip is used for carrying out data operation and controlling the data transmitted by the monitoring module;
the temperature control module is positioned in a pipeline between the ultrafiltrate pump and the biological module, is connected with the operation control chip and is used for automatically cooling or heating;
the current and voltage acquisition module is used for acquiring an electric signal of the sensor;
the filtering module comprises a heparin pump, a blood filtering device, an ultrafiltrate pump and a degassing device which are sequentially connected by utilizing a fluid pipeline.
The biological module comprises a biological reactor and a fluid pipeline, wherein the biological reactor is communicated with a fluid pipeline between an ultrafiltrate pump of the filtering module and a degassing device through the fluid pipeline, the biological reactor can be a biological reactor in the literature (DOI: 10.1111/j.1523-1755.2004.00923.X; DOI:10.1002/adhm.202101606; DOI: 10.1016/j.talanta.2006.04.023), and contains cells or enzymes for filtering toxic substances in blood, the hemofiltration device is used for filtering blood, the blood enters the hemofiltration device from the fluid pipeline through a driving module to generate ultrafiltrate, then the blood and the filtrate respectively enter two chambers of the biological reactor after passing through the hemofiltration device, the blood flows back to a human body through the fluid pipeline, and the filtrate finally flows to a waste liquid bag;
the monitoring module comprises a first blood pressure sensor, a flow sensor, a temperature sensor, a second blood pressure sensor, a blood viscosity sensor, a blood leakage sensor and a bubble sensor, wherein the first blood pressure sensor and the second blood pressure sensor are used for detecting the blood pressure in a fluid pipeline, the bubble sensor is used for detecting whether bubbles exist in the fluid pipeline, the flow sensor is used for detecting the fluid flow in the fluid pipeline, and the blood viscosity sensor is used for detecting the viscosity of liquid in blood;
the first blood pressure sensor detection end is connected with the pipeline fluid between the blood pump and the blood filtering device and used for detecting the blood pressure;
the detection end of the flow sensor is connected with the pipeline fluid between the hemofiltration device and the bioreactor, and detects the flow rate of filtrate filtered by the hemofiltration device;
the temperature sensor detection end is connected with the pipeline fluid between the hemofiltration device and the bioreactor and is used for detecting the temperature of filtrate filtered by the hemofiltration device;
the detection end of the dissolved oxygen sensor is connected with pipeline fluid between the ultrafiltration pump and the biological module, and detects the oxygen content of filtrate entering the biological module;
the detection end of the pH sensor is connected to the pipeline fluid of the biological reaction module, and the pH value of the filtrate flowing out of the biological module is detected;
the detection end of the second blood pressure sensor is connected with the pipeline fluid between the biological module and the degassing device and used for detecting the blood pressure;
the detection end of the blood viscosity sensor is connected with the pipeline fluid between the biological module and the degassing device to detect the blood viscosity;
the detection end of the blood glucose sensor is connected with pipeline fluid between the biological module and the degassing device, and the glucose content in the blood pipeline is detected;
the detection end of the bubble sensor is connected with the pipeline fluid between the biological module and the degassing device and used for detecting whether bubbles are generated in the blood pipeline;
the detection end of the blood leakage sensor is connected with the pipeline fluid between the biological module and the degassing device and used for detecting whether blood leakage occurs in the blood pipeline;
in this embodiment, the fluid pipeline is sequentially connected with a heparin pump, a blood pump, a first blood pressure sensor, a hemofiltration device, an ultrafiltrate pump, a flow sensor, a temperature control module, a dissolved oxygen sensor, a pH sensor, a biological reaction module, a second blood pressure sensor, a blood viscosity sensor, a blood glucose sensor, a bubble sensor, a blood leakage sensor and a degassing device, blood is finally returned to the human body through the degassing device, all sensors in the system are provided with corresponding current and voltage acquisition modules, the current and voltage acquisition modules are amplified by signals and then pass through a filter circuit, and a filter signal output by the filter circuit is converted into a digital signal through an A/D conversion module and then transmitted to an operation control chip. The sensor is connected with the operation control chip through the sensor identification module, and different sensors are identified through the sensor identification module and the identification result is transmitted to the operation control chip.
In this embodiment, the device further includes an exchange component, where the exchange component includes an LCD display module and a storage module, where the operation control chip is connected with the storage module and the LCD display module, where the LCD display module is used to display the detected value obtained by processing the operation control chip, and the storage module is used to store the detected value obtained by processing the operation control chip. The method is characterized in that when in specific implementation: the LCD display module can display the data on a display screen of the dialysis machine, the operation control chip performs operation processing to detect the numerical value, a numerical value curve or list is generated, the display module displays the numerical value on the display screen, and the storage module stores the numerical value of the operation control chip.
In this embodiment, the portable electronic device further includes a key module and a power module, where the power module is electrically connected to the operation control chip, the power module is used to provide electric energy, and the key module is used for user operation. The method is characterized in that when in specific implementation: the power module can provide electric energy for other modules to maintain the normal operation of other modules, and the key module can facilitate the data interaction between users and the system and the operation control system of the user.
In this embodiment, the device further includes a temperature control module, where the temperature control module is connected to the operation control chip. The method is characterized in that when in specific implementation: the temperature sensor can detect the temperature in the fluid pipeline, the operation control chip is used for cooling the fluid pipeline when the temperature is too high according to the setting, and the temperature control module is used for heating the fluid pipeline when the temperature is too low.
In this embodiment, the hemodialysis machine system further includes a temperature compensation module, the temperature compensation module is connected to the operation control chip, the operation control chip determines whether to output a temperature compensation signal, and the operation control chip transmits the temperature compensation signal to the temperature compensation module.
In this embodiment, a blood glucose sensor for detecting the blood glucose concentration in blood is further included. The method is characterized in that when in specific implementation: before blood flows back into the human body, the filtered blood can be degassed by the degassing device, the filtered blood is conveyed back to the inside of the human body after being degassed, the degassing device can ensure that the blood returned to the human body does not contain bubbles, the human body is prevented from generating air embolism, and the blood glucose sensor can be used for monitoring the concentration of blood glucose in the blood.
In some embodiments, as shown in fig. 2, the switching assembly further includes a data interface module and a wireless transmission module, the operation control chip is respectively connected with the data interface module and the wireless transmission module, the data interface module is used for implementing data communication of different software, and the wireless transmission module is used for converting the serial port data into wireless network data. The method is characterized in that when in specific implementation: the data interface module and the wireless transmission module can realize data communication, so that on-line communication between medical staff and patients is realized, for example, the wireless transmission module converts serial data into wireless network data, the wireless network data is transmitted to the outside, different software is displayed through the data interface module, the data is transmitted to the software on line for feedback storage, then the medical staff realizes on-line communication through feedback, and the data interface module and the wireless transmission module are used for transmitting detection values obtained through the operation control chip.
In some embodiments, as in fig. 3, the hemodialysis machine system further includes a drive module, which in this embodiment includes a first drive motor electrically connected to the heparin pump, a second drive motor electrically connected to the blood pump, and a third drive motor electrically connected to the ultrafiltrate pump. The first motor is used for driving the heparin pump, the second driving motor is used for driving the blood pump, and the third driving motor is used for the ultrafiltrate pump.
In some embodiments, as shown in fig. 4, the hemodialysis machine system further includes a buzzer module connected to the operation control chip, where the buzzer module is configured to generate a warning tone to alarm an abnormal situation. The method is characterized in that when in specific implementation: the buzzer module can be used for alarming, and the buzzer module alarms when the temperature is too low, the pressure of the fluid pipeline is too high, the fluid pipeline leaks blood, bubbles appear in blood and the like, so that timely reminding of a user is completed.
Of course, the present utility model can be implemented in various other embodiments, and based on this embodiment, those skilled in the art can obtain other embodiments without any inventive effort, which fall within the scope of the present utility model.
Claims (8)
1. The utility model provides a biological hemodialysis machine system, its characterized in that, biological hemodialysis machine system includes operation control chip, control by temperature change module, filtration module, biological module, monitoring module, electric current voltage acquisition module and signal amplification module, wherein:
the filtering module comprises a heparin pump, a blood filtering device, an ultrafiltrate pump and a degassing device which are sequentially connected through fluid pipelines;
the biological module comprises a biological reactor which is communicated with a fluid pipeline between an ultrafiltrate pump of the filtering module and the degassing device through the fluid pipeline;
the temperature control module is positioned in a pipeline between the ultrafiltrate pump and the biological module and is connected with the operation control chip;
the monitoring module comprises a first blood pressure sensor, a blood sugar sensor, a temperature sensor, a flow sensor, a second blood pressure sensor, a blood viscosity sensor, a pH sensor, a dissolved oxygen sensor, a blood leakage sensor and a bubble sensor;
the temperature sensor detection end is connected with pipeline fluid between the hemofiltration device and the bioreactor, the first blood pressure sensor detection end is connected with pipeline fluid between the blood pump and the hemofiltration device, the dissolved oxygen sensor detection end is connected with pipeline fluid between the ultrafiltration pump and the biological module, the pH sensor detection end is connected with pipeline fluid of the biological reaction module, the second blood pressure sensor detection end is connected with pipeline fluid between the biological module and the degassing device, the blood viscosity sensor detection end is connected with pipeline fluid between the biological module and the degassing device, the blood glucose sensor detection end is connected with pipeline fluid between the biological module and the degassing device, the bubble sensor detection end is connected with pipeline fluid between the biological module and the degassing device, and the blood leakage sensor detection end is connected with pipeline fluid between the biological module and the degassing device;
the sensor of the monitoring module is connected with the operation control chip through the current and voltage acquisition module and the signal amplification module.
2. The biological hemodialysis machine system of claim 1, further comprising a drive module, the drive module being connected to the arithmetic control chip;
the driving module comprises a first driving motor, a second driving motor and a third driving motor;
the first driving motor is electrically connected with the heparin pump, the second driving motor is electrically connected with the blood pump, and the third driving motor is electrically connected with the ultrafiltrate pump.
3. The biological hemodialysis machine system of claim 1, further comprising an exchange assembly including an LCD display module and a storage module, wherein the arithmetic control chip is connected to the storage module and the LCD display module, respectively.
4. The biological hemodialysis machine system of claim 3, wherein the exchange assembly further comprises a data interface module and a wireless transmission module, and the arithmetic control chip is respectively connected with the data interface module and the wireless transmission module.
5. The biological hemodialysis machine system of claim 1, further comprising a buzzer module connected to the arithmetic control chip.
6. The biological hemodialysis machine system of claim 1, further comprising a temperature compensation module, the temperature compensation module being coupled to the operational control chip.
7. The biological hemodialysis machine system of claim 1, further comprising a key module and a power module, wherein the power module, the key module, and the operational control chip are electrically connected.
8. The biological hemodialysis machine system of claim 1, further comprising a filter circuit and an a/D conversion module, wherein the signal amplification module, the filter circuit, the a/D conversion module, and the operation control chip are connected in sequence.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN202320439922.7U CN219896581U (en) | 2023-03-10 | 2023-03-10 | Biological hemodialysis machine system |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202320439922.7U CN219896581U (en) | 2023-03-10 | 2023-03-10 | Biological hemodialysis machine system |
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| CN219896581U true CN219896581U (en) | 2023-10-27 |
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| CN202320439922.7U Active CN219896581U (en) | 2023-03-10 | 2023-03-10 | Biological hemodialysis machine system |
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