CN219836000U - Full-automatic drug delivery device for lung surfactant - Google Patents
Full-automatic drug delivery device for lung surfactant Download PDFInfo
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- CN219836000U CN219836000U CN202321298498.5U CN202321298498U CN219836000U CN 219836000 U CN219836000 U CN 219836000U CN 202321298498 U CN202321298498 U CN 202321298498U CN 219836000 U CN219836000 U CN 219836000U
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- piston
- liquid injection
- liquid
- cylinder body
- fully automatic
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- 239000003580 lung surfactant Substances 0.000 title claims description 23
- 238000012377 drug delivery Methods 0.000 title abstract description 8
- 229940066294 lung surfactant Drugs 0.000 title description 5
- 239000007788 liquid Substances 0.000 claims abstract description 78
- 238000002347 injection Methods 0.000 claims abstract description 61
- 239000007924 injection Substances 0.000 claims abstract description 61
- 210000002445 nipple Anatomy 0.000 claims abstract description 13
- 238000001647 drug administration Methods 0.000 claims description 5
- 210000004072 lung Anatomy 0.000 abstract description 3
- 239000013543 active substance Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 11
- 229940079593 drug Drugs 0.000 description 10
- 238000000034 method Methods 0.000 description 5
- 210000003437 trachea Anatomy 0.000 description 5
- 206010001052 Acute respiratory distress syndrome Diseases 0.000 description 3
- 208000013616 Respiratory Distress Syndrome Diseases 0.000 description 3
- 241000272525 Anas platyrhynchos Species 0.000 description 2
- 238000001802 infusion Methods 0.000 description 2
- 230000002028 premature Effects 0.000 description 2
- 230000000750 progressive effect Effects 0.000 description 2
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 206010011703 Cyanosis Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 208000032571 Infant acute respiratory distress syndrome Diseases 0.000 description 1
- 206010028974 Neonatal respiratory distress syndrome Diseases 0.000 description 1
- 208000004756 Respiratory Insufficiency Diseases 0.000 description 1
- 206010038687 Respiratory distress Diseases 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 238000009098 adjuvant therapy Methods 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000003595 mist Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 201000002652 newborn respiratory distress syndrome Diseases 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 230000011514 reflex Effects 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 201000004193 respiratory failure Diseases 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000009469 supplementation Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The utility model discloses a full-automatic drug delivery device for lung surface active substances, which comprises a cylinder body, a liquid injection rod, a first piston, a second piston, a nipple and pre-filling liquid; the nipple is arranged at the bottom of the cylinder body; the first piston and the second piston are arranged on the inner wall of the cylinder body and in interference fit with the inner wall of the cylinder body, and the second piston is positioned above the first piston; the prefilling liquid is filled in a first cavity formed by the first piston, the second piston and the cylinder; the radius of the second piston is larger than that of the first piston; the liquid injection rod penetrates through the second piston and is fixedly connected with the second piston; the bottom of the liquid injection rod is detachably connected with the upper end of the first piston. The utility model is integrally formed, so that the steps of disassembling the push rod, installing the connector, exhausting and the like are omitted, and the operation is simpler and more convenient.
Description
Technical Field
The utility model belongs to the field of medical instruments, and particularly relates to a full-automatic pulmonary surfactant feeder.
Background
Neonatal Respiratory Distress Syndrome (RDS) is a common respiratory disease that is well developed in premature infants, and it is currently believed that its occurrence is closely related to the lack of lung surfactant (Pulmonary Surfactant, PS). RDS clinical manifestations are shortness of breath, progressive respiratory distress, cyanosis and respiratory failure in the short term after delivery, if not timely rescuing the mortality rate is high. Exogenous PS supplementation has been used in great numbers today for RDS adjuvant therapy in premature infants and has shown significant advantages in improving overall prognosis.
The current common exogenous PS administration methods include INSERE technology and LISA/MIST technology, wherein PS is injected into alveoli through a pipeline by adopting a manual pushing syringe method, and the method has the following problems: the PS injection speed is slow, preferably not less than 15min, and occupies the time of medical staff in the neonatal intensive care unit; 2. the manual pushing of the injector is difficult to control, the PS injection speed is too high, the respiratory tract blockage, the heart rate blood oxygen fluctuation, the choking and cough reflex, the PS reflux and the drug loss are easily caused; 2. the exogenous PS is expensive, the dosage of each time is only 1-3 ml, the PS can directly enter alveoli as much as possible to improve the therapeutic effect of unit medicines, the PS injection pipeline is too long, and PS is stained on the inner wall of the pipeline to cause medicine waste.
Automated handling, good dosing speed and reduced PS passage length are therefore of great importance in exogenous PS dosing processes. The PS automatic drug delivery device in the prior art still has some technical problems, for example, the automatic drug delivery device CN202220568447.9 for pulmonary surfactant is actually applied, and some problems of the original device still need to be further improved: 1. the original device lacks of fixed arrangement, needs to be fixed by external articles such as rubberized fabric, rope buckles and the like, and is inconvenient to use; 2. the original device needs to disassemble the push rod, install the connector, exhaust, and the like, and has complicated operation; 3. the exhaust of the outer cavity of the hollow cylinder of the original device easily causes the downward movement of the piston, the operation is very careful, the PS loss is easy to be caused, and the operation is inconvenient.
Disclosure of Invention
In order to solve the technical problems, the utility model provides a full-automatic pulmonary surfactant feeder, and when in drug delivery, a piston can stably push PS into a tracheal cannula, so that the operation is convenient.
The technical scheme of the utility model is as follows:
a full-automatic drug delivery device for pulmonary surfactant,
comprises a cylinder body, a liquid injection rod, a first piston, a second piston, a nipple and pre-filling liquid;
the nipple is arranged at the bottom of the cylinder body;
the first piston and the second piston are arranged on the inner wall of the cylinder body and in interference fit with the inner wall of the cylinder body, and the second piston is positioned above the first piston;
the prefilling liquid fills the hollow cavity of the injection rod and the first cavity formed by the first piston, the second piston and the cylinder;
the radius of the second piston is larger than that of the first piston;
the liquid injection rod penetrates through the second piston and is fixedly connected with the second piston;
the bottom of the liquid injection rod is detachably connected with the upper end of the first piston.
The upper end of the liquid injection rod is provided with a liquid injection joint which is used for being connected with an external extension tube; and a duckbill valve is arranged in the liquid injection joint.
Wherein, annotate the liquid joint outside and still be equipped with detachable lid.
Wherein, the cap with annotate the outside interference fit of liquid joint.
The bottom of the liquid injection rod is detachably connected with the upper end of the first piston in a concrete mode, the upper end of the first piston is provided with a screw hole which does not penetrate through the first piston, the outer side of the bottom end of the liquid injection rod is provided with a thread structure, and the bottom end of the liquid injection rod is in threaded connection with the first piston through the screw hole.
Wherein, the outer wall at barrel upper portion is equipped with fixed subassembly.
The fixing assembly is an annular piece with a clamping groove, an annular chute is formed in the outer wall of the upper portion of the barrel, and the annular piece can be rotatably installed in the annular chute.
Wherein, the side wall of the cylinder body is provided with scales.
Wherein, the utility model also comprises a liquid sucking needle and a drug administration needle.
The needle stem of the liquid sucking needle is vertical, and the needle stem of the drug administration needle is a 45-degree elbow.
Compared with the background art, the full-automatic pulmonary surfactant feeder comprises a cylinder, a liquid injection rod, a first piston, a second piston, a nipple and pre-filling liquid; the nipple is arranged at the bottom of the cylinder body; the first piston and the second piston are arranged on the inner wall of the cylinder body and in interference fit with the inner wall of the cylinder body, and the second piston is positioned above the first piston; the prefilling liquid fills the hollow cavity of the injection rod and the first cavity formed by the first piston, the second piston and the cylinder; the radius of the second piston is larger than that of the first piston; the liquid injection rod penetrates through the second piston and is fixedly connected with the second piston; the bottom of the liquid injection rod is detachably connected with the upper end of the first piston.
The utility model has the following advantages:
1. the structure is simple, the operation is full-automatic, and the labor is saved;
2. the combination with the trachea cannula is more flexible and stable;
3. adverse reactions and drug losses caused by too fast administration are avoided;
4. shortening PS pipeline and reducing PS loss
5. The device is integrally formed, the push rod is removed, the connector is installed, the exhaust is realized, the operation is simple and convenient, the operation steps are fewer, and the device is simpler.
Drawings
FIG. 1 is a schematic diagram of the structure of the present utility model;
FIG. 2 is a schematic view of the structure of the liquid injection rod;
FIG. 3 is a top view of the first piston;
FIG. 4 is a schematic structural view of a fixing assembly;
in the figure, a liquid injection rod 1, a fixing assembly 2, a cylinder 3, a first piston 4, a second piston 5, a prefill liquid 6, a nipple 7, a liquid injection joint 11, a duckbill valve 12, a cap 13, a thread structure 14, a screw hole 41, an annular piece 21, a clamping groove 22, an annular chute 31, a scale 32, a drug delivery needle 8, an external syringe 9, an external extension tube 10 and an tracheal cannula 101.
Detailed Description
In order to better understand the aspects of the present utility model, the present utility model will be described in further detail with reference to the accompanying drawings and detailed description.
The utility model adopts a progressive description method.
As shown in fig. 1 to 4, a full-automatic pulmonary surfactant feeder comprises a cylinder 3, a liquid injection rod 1, a first piston 4, a second piston 5, a nipple 7 and a prefill liquid 6;
the nipple 7 is arranged at the bottom of the cylinder 3;
the first piston 4 and the second piston 5 are arranged on the inner wall of the cylinder body 3 and in interference fit with the inner wall of the cylinder body 3, and the second piston 5 is positioned above the first piston 4;
the prefilling liquid 6 is filled in a first cavity formed by the first piston 4, the second piston 5 and the cylinder 3;
the radius of the second piston 5 is slightly larger than the radius of the first piston 4;
the liquid injection rod 1 penetrates through the second piston 5 and is fixedly connected with the second piston 5;
the bottom of the liquid injection rod 1 is detachably connected with the upper end of the first piston 4.
Drug inhalation and exhaust: when the PS injection device is used, the nipple 7 on the cylinder body 3 is connected with the drug sucking needle, the drug sucking needle is inserted into a bottle filled with PS, the injection rod 1 is pulled outwards, PS is sucked into a second cavity formed by the first piston 4 and the bottom of the cylinder body 3, the drug sucking needle is pulled out from the nipple 7 after the suction is finished, the drug feeding needle 8 is installed, proper air is exhausted, and proper air is reserved in the second cavity, so that the reserved air can flush PS into lung tissues as much as possible after PS passes through a pipeline during drug feeding, PS loss is reduced, and the air quantity is generally 2 times of the PS passing path volume.
Separating: the liquid injection rod 1 is rotated, and the bottom of the liquid injection rod 1 is separated from the upper end of the first piston 4.
And (3) connection: the external injector 9 absorbs a proper amount of liquid which is the same as the pre-filling liquid 6, is connected with the external extension tube 10 and exhausts, the external injector 9 is arranged on the external injection pump, and the upper end of the liquid injection rod 1 is connected with the external extension tube 10.
Fixing: the tip of the administration needle 8 is inserted into the endotracheal tube 101 at a distance of 2-3cm from the upper lip, and the annular member 21 is rotated to select a suitable size of the clip groove 22 to be fixed to the endotracheal tube 101.
Administration: starting an external injection pump, adjusting proper infusion speed parameters, starting infusion administration, and injecting liquid in an external injector 9 into a first cavity through an external extension tube 10 and a hollow liquid injection rod, wherein the liquid in the first cavity is increased, and the pressure is increased; the radius of the second piston 5 is larger than that of the first piston 4, the friction force between the second piston 5 and the inner wall of the cylinder 3 is larger than that between the first piston 4 and the inner wall of the cylinder 3, at the moment, the first piston 4 moves downwards to push PS in the second cavity gap into the tracheal cannula 101, so that PS can enter the airway and lung tissues, and the treatment purpose is achieved.
In general, the prefilled liquid 6 may be physiological saline or a clinically common solution such as sterilized injection water.
The upper end of the liquid injection rod 1 is provided with a liquid injection joint 11 which is used for being connected with an external injector 9; the duck bill valve 12 is arranged in the liquid injection joint 11, the liquid injection joint 11 can be connected with the external extension tube 10 of an external syringe, the duck bill valve 12 plays a role of a one-way valve, and the pre-filling liquid 6 is prevented from flowing out from the liquid injection joint 11.
The outside of the liquid injection joint 11 is also provided with a detachable cap 13, and the cap 13 is used for being matched with the liquid injection joint 11 and protecting the prefilled liquid 6 from flowing out of the liquid injection joint 11 when not in use.
According to the utility model, the cap 13 is in interference fit with the outside of the liquid injection joint 11, so that the tightness of the cap 13 and the liquid injection joint 11 can be further ensured.
The bottom of the liquid injection rod 1 is detachably connected with the upper end of the first piston 4 in the concrete manner that a screw hole 41 which does not penetrate is formed in the upper end of the first piston 4, a thread structure 14 is arranged on the outer side of the bottom end of the liquid injection rod 1, and the bottom end of the liquid injection rod 1 is in threaded connection with the first piston 4. When the liquid injection rod 1 needs to be detached or installed, the purpose of detachment and installation can be achieved by rotating the liquid injection rod 1.
The liquid injection rod 1 of the utility model is of a hollow structure and is respectively opened at two ends of the liquid injection joint 11 and the thread structure 14.
The outer wall of the upper part of the cylinder 3 is provided with an annular chute 31.
The outer wall of the upper part of the cylinder body 3 is also provided with a fixing component 2.
The fixing component 2 of the utility model is a ring-shaped piece 21 with a clamping groove 22, and the ring-shaped piece 21 is arranged in the ring-shaped chute 31 and can rotate and move. The clamping groove 22 is used for being fixed with the trachea cannula 101, and the annular piece 21 can be adjusted in position in the annular sliding groove 31, so that the full-automatic lung surfactant feeder can be better matched with the trachea cannula 101, and further the full-automatic lung surfactant feeder can be fixed.
The clamping groove 22 has various sizes, can be suitable for the outer diameters of trachea cannula with different models, and is used for fixing the full-automatic pulmonary surfactant feeder on the trachea cannula 101.
The side wall of the cylinder body 3 is provided with scales 32, so that medical staff can observe the dosage.
The utility model also includes a pipette tip and an administration tip 8.
The needle stem of the liquid sucking needle head is vertical, and the needle stem of the drug administration needle head 8 is a 45-degree elbow.
The device needs to be used for an external injection pump, an external injector 9, an external extension tube 10 and normal saline, and the articles are stock instruments and medicines for the ward of the infant and are not in the scope of the utility model.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present utility model. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the utility model. Thus, the present utility model is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (10)
1. A fully automatic pulmonary surfactant feeder, characterized in that:
comprises a cylinder body (3), a liquid injection rod (1), a first piston (4), a second piston (5), a nipple (7) and a pre-filling liquid (6);
the nipple (7) is arranged at the bottom of the cylinder (3);
the first piston (4) and the second piston (5) are arranged on the inner wall of the cylinder body (3) and in interference fit with the inner wall of the cylinder body (3), and the second piston (5) is positioned above the first piston (4);
the prefilling liquid (6) is filled in a first cavity formed by the first piston (4), the second piston (5) and the cylinder body (3);
the radius of the second piston (5) is larger than that of the first piston (4);
the liquid injection rod (1) penetrates through the second piston (5) and is fixedly connected with the second piston (5);
the bottom of the liquid injection rod (1) is detachably connected with the upper end of the first piston (4).
2. The fully automatic pulmonary surfactant dispenser of claim 1, wherein:
the upper end of the liquid injection rod (1) is provided with a liquid injection joint (11) which is used for being connected with an external extension tube; the liquid injection joint (11) is internally provided with a duckbill valve (12) for preventing backflow.
3. The fully automatic pulmonary surfactant dispenser of claim 2, wherein:
the outside of the liquid injection joint (11) is also provided with a detachable cap (13).
4. A fully automatic pulmonary surfactant dispenser according to claim 3, wherein:
the cap (13) is in interference fit with the outside of the liquid injection joint (11).
5. The fully automatic pulmonary surfactant dispenser of claim 4, wherein:
the bottom of annotating liquid pole (1) with the concrete mode of connection can be dismantled to the upper end of first piston (4) is, the upper end of first piston (4) is equipped with screw (41) that do not run through, the bottom outside of annotating liquid pole (1) is equipped with screw structure (14), the bottom of annotating liquid pole (1) with first piston (4) carries out threaded connection through screw (41).
6. The fully automatic pulmonary surfactant dispenser of claim 5, wherein:
the outer wall of the upper part of the cylinder body (3) is provided with a fixing component (2).
7. The fully automatic pulmonary surfactant dispenser of claim 6, wherein:
the fixing assembly (2) is an annular piece (21) with a clamping groove (22), an annular chute (31) is formed in the outer wall of the upper portion of the cylinder body (3), and the annular piece (21) can be rotatably installed in the annular chute (31).
8. The fully automatic pulmonary surfactant dispenser of claim 7, wherein:
the side wall of the cylinder body (3) is provided with scales (32).
9. The fully automatic pulmonary surfactant dispenser of claim 8, wherein:
also comprises a liquid sucking needle and a drug administration needle (8).
10. The fully automatic pulmonary surfactant dispenser of claim 9, wherein:
the needle stem of the liquid sucking needle head is vertical, and the needle stem of the drug administration needle head (8) is a 45-degree elbow.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321298498.5U CN219836000U (en) | 2023-05-25 | 2023-05-25 | Full-automatic drug delivery device for lung surfactant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321298498.5U CN219836000U (en) | 2023-05-25 | 2023-05-25 | Full-automatic drug delivery device for lung surfactant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219836000U true CN219836000U (en) | 2023-10-17 |
Family
ID=88300689
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321298498.5U Active CN219836000U (en) | 2023-05-25 | 2023-05-25 | Full-automatic drug delivery device for lung surfactant |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219836000U (en) |
-
2023
- 2023-05-25 CN CN202321298498.5U patent/CN219836000U/en active Active
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